Positioning of second‐line treatment for advanced gastric and gastroesophageal junction adenocarcinoma
Pericay, Carles, Rivera, Fernando, Gomez‐Martin, Carlos, Nuñez, Inmaculada, Cassinello, Alejo, Imedio, Esteban Rodrigo
Published in Cancer medicine (Malden, MA) (01.12.2016)
Published in Cancer medicine (Malden, MA) (01.12.2016)
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Adavosertib with Chemotherapy in Patients with Primary Platinum-Resistant Ovarian, Fallopian Tube, or Peritoneal Cancer: An Open-Label, Four-Arm, Phase II Study
Moore, Kathleen N, Chambers, Setsuko K, Hamilton, Erika P, Chen, Lee-May, Oza, Amit M, Ghamande, Sharad A, Konecny, Gottfried E, Plaxe, Steven C, Spitz, Daniel L, Geenen, Jill J J, Troso-Sandoval, Tiffany A, Cragun, Janiel M, Rodrigo Imedio, Esteban, Kumar, Sanjeev, Mugundu, Ganesh M, Lai, Zhongwu, Chmielecki, Juliann, Jones, Suzanne F, Spigel, David R, Cadoo, Karen A
Published in Clinical cancer research (01.01.2022)
Published in Clinical cancer research (01.01.2022)
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391 A first-in-human study of intratumoral SAR441000, an mRNA mixture encoding IL-12sc, interferon alpha2b, GM-CSF and IL-15sushi as monotherapy and in combination with cemiplimab in advanced solid tumors
Bechter, Oliver, Utikal, Jochen, Baurain, Jean-Francois, Massard, Christophe, Sahin, Ugur, Derhovanessian, Evelyna, Ozoux, Marie-Laure, Marpadga, Rahul, Imedio, Esteban-Rodrigo, Acquavella, Nicolas, Loquai, Carmen
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Safety and efficacy of sorafenib in the treatment of advanced hepatocellular carcinoma: a single center experience
Imedio, Esteban Rodrigo, Beveridge, Roberto Díaz, Urtasun, Jorge Aparicio, Campos, Gema Bruixola, Estellés, David Lorente, Esparcia, María Fonfría, Daroqui, Javier Caballero, Huerta, Ángel Segura, Órtiz, Alejandra Giménez, Salcedo, Joaquin Montalar
Published in Medical oncology (Northwood, London, England) (01.05.2014)
Published in Medical oncology (Northwood, London, England) (01.05.2014)
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A phase 1 dose-finding and dose-expansion study evaluating the safety, tolerability, pharmacokinetics, and efficacy of a highly selective WEE1 inhibitor (Debio 0123) in adult patients with advanced solid tumors
Papadopoulos, Kyriakos P., Sharma, Manish, Dummer, Reinhard, Rodrigo Imedio, Esteban, Yge, Marie-Laurence, Micallef, Sandrine, Bellon, Anne, Stathis, Anastasios
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Debio 0123-101: A phase 1 trial of Debio 0123 in combination with carboplatin in advanced solid tumors—Safety, pharmacokinetic, and preliminary antitumor activity data
Gelderblom, Hans, Jalving, Mathilde, Desar, Ingrid, Saavedra, Omar, Gietema, Jourik A., van Ravensteijn, Stefan, Ajmone Marsan, Nina, Bellon, Anne, Micallef, Sandrine, Luong, Noemie, Piggott, Luke, Frederiksen Franzen, Rikke, Rodrigo Imedio, Esteban
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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RTID-03. A PHASE 1/2 STUDY OF THE WEE1 INHIBITOR DEBIO 0123 IN COMBINATION WITH TEMOZOLOMIDE +- RADIOTHERAPY IN ADULTS WITH RECURRENT OR NEWLY DIAGNOSED GLIOBLASTOMA
Roth, Patrick, Papadopoulos, Kyriakos P, Vieito, Maria, Yang, Jonathan, Majd, Nazanin, Sepúlveda, Juan, Schaff, Lauren, Moreno, Victor, Pérez -Larraya, Jaime Gállego, Micallef, Sandrine, Bellon, Anne, Omar, Mokhtar, Imedio, Esteban Rodrigo, Piggott, Luke, Rodriguez-Freixinos, Victor, Rodon, Jordi
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
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A phase Ib study of adavosertib, a selective Wee1 inhibitor, in patients with locally advanced or metastatic solid tumors
Falchook, Gerald S, Sachdev, Jasgit, Imedio, Esteban Rodrigo, Kumar, Sanjeev, Mugundu, Ganesh M, Jenkins, Suzanne, Chmielecki, Juliann, Jones, Suzanne, Spigel, David R, Johnson, Melissa
Published in Investigational new drugs (01.06.2023)
Published in Investigational new drugs (01.06.2023)
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Abstract OT2-08-02: Capivasertib and paclitaxel in first-line treatment of patients with metastatic triple-negative breast cancer: A phase III trial (CAPItello-290)
Schmid, Peter, Cortes, Javier, Robson, Mark, Iwata, Hiroji, Hegg, Roberto, Verma, Sunil, Nechaeva, Marina, Xu, Binghe, Haddad, Vincent, Imedio, Esteban Rodrigo, Schiavon, Gaia, Foxley, Andrew, Park, Yeon Hee
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Published in Cancer research (Chicago, Ill.) (15.02.2020)
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Abstract CT022: A Phase Ib study of Wee1 inhibitor adavosertib in patients with advanced solid tumors
Falchook, Gerald S., Sachdev, Jasgit, Imedio, Esteban Rodrigo, Kumar, Sanjeev, Mugundu, Ganesh, Chmielecki, Juliann, Jones, Suzanne, Spigel, David R., Johnson, Melissa
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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A phase III trial of capivasertib and paclitaxel in first-line treatment of patients with metastatic triple-negative breast cancer (CAPItello290)
Schmid, Peter, Cortes, Javier, Robson, Mark E., Iwata, Hiroji, Hegg, Roberto, Nechaeva, Marina, Xu, Binghe, Verma, Sunil, Haddad, Vincent, Rodrigo Imedio, Esteban, Schiavon, Gaia, Foxley, Andrew, Park, Yeon Hee
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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A Phase Ib Study Assessing the Safety, Tolerability, and Efficacy of the First-in-Class Wee1 Inhibitor Adavosertib (AZD1775) as Monotherapy in Patients with Advanced Solid Tumors
Bauer, Todd M., Moore, Kathleen N., Rader, Janet S., Simpkins, Fiona, Mita, Alain C., Beck, J. Thaddeus, Hart, Lowell, Chu, Quincy, Oza, Amit, Tinker, Anna V., Imedio, Esteban Rodrigo, Kumar, Sanjeev, Mugundu, Ganesh, Jenkins, Suzanne, Chmielecki, Juliann, Jones, Suzanne, Spigel, David, Fu, Siqing
Published in Targeted oncology (01.07.2023)
Published in Targeted oncology (01.07.2023)
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Abstract CT025: Phase Ib study of adavosertib in combination with olaparib in patients with refractory solid tumors: Dose escalation
Hamilton, Erika, Falchook, Gerald S., Wang, Judy S., Fu, Siqing, Oza, Amit, Karen, So, Imedio, Esteban Rodrigo, Kumar, Sanjeev, Ottesen, Lone, Mugundu, Ganesh M., Chmielecki, Juliann, Jones, Suzanne, Spigel, David R., Li, Bob T.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Open-label, multicenter, phase I study to assess safety and tolerability of adavosertib plus durvalumab in patients with advanced solid tumors
Patel, Manish R., Falchook, Gerald Steven, Wang, Judy Sing-Zan, Rodrigo Imedio, Esteban, Kumar, Sanjeev, Motlagh, Pejvack, Miah, Kowser, Mugundu, Ganesh M., Jones, Suzanne Fields, Spigel, David R., Hamilton, Erika Paige
Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
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Abstract CT012: Open-label, multicenter, Phase Ib study to assess safety, tolerability and efficacy of adavosertib monotherapy in patients with advanced solid tumors: Expansion cohorts
Bauer, Todd M., Moore, Kathleen, Rader, Janet S., Simpkins, Fiona, Mita, Alain, Beck, J Thaddeus, Hart, Lowell, Chu, Quincy, Oza, Amit, Tinker, Anna V., So, Karen, Imedio, Esteban Rodrigo, Kumar, Sanjeev, Mugundu, Ganesh M., Jenkins, Suzanne, Chmielecki, Juliann, Jones, Suzanne, Spigel, David R., Fu, Siqing
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Adavosertib with chemotherapy (CT) in patients (pts) with platinum-resistant ovarian cancer (PPROC): An open label, four-arm, phase II study
Moore, Kathleen N., Chambers, Setsuko K., Hamilton, Erika Paige, Chen, Lee-may, Oza, Amit M., Ghamande, Sharad A., Konecny, Gottfried E., Plaxe, Steven C., Spitz, Daniel Lewis, Geenen, Jill J.J., Troso-Sandoval, Tiffany A., Cragun, Janiel M., Rodrigo Imedio, Esteban, Kumar, Sanjeev, Mugundu, Ganesh M., Lai, Zhongwu, Chmielecki, Juliann, Jones, Suzanne Fields, Spigel, David R., Cadoo, Karen Anne
Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
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Journal Article
Abstract CT064: Impact of food and high gastric pH on the bioavailability of the WEE1 inhibitor Debio 0123 assessed in a phase 1 dose escalation study
Bellon, Anne, Saavedra, Omar, Desar, Ingrid M., Jalving, Mathilde, Gietema, Jourik A., van Herpen, Carla, van Ravensteijn, Stefan, Imedio, Esteban Rodrigo, van Haren, Sylvia, Wirth, Melanie, Micallef, Sandrine, Dozio, Vito, Franzen, Rikke Frederiksen, Roubaudi-Fraschini, Marie-Claude, Nicolas-Metral, Valerie, Gelderblom, Hans
Published in Cancer research (Chicago, Ill.) (05.04.2024)
Published in Cancer research (Chicago, Ill.) (05.04.2024)
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Phase II trial of afatinib in patients with advanced/metastatic urothelial carcinoma (UC) with genetic alterations in ERBB receptors 1-3 who failed on platinum-based chemotherapy (CT)
Font Pous, Albert, Puente, Javier, Castellano, Daniel E., Real, Francisco X., Climent, Miguel A., Gonzalez del Alba, Aranzazu Aranzazu, Oudard, Stephane, Vazquez Mazon, Federico Jose, Morales Barrera, Rafael, Virizuela, Juan Virizuela, Sala, Nuria, Pérez-Valderrama, Begoña, Garcia del Muro, Xavier, Fernandez, Pedro L., Jares, Pedro, Aldecoa, Iban, Gibson, Neil, Serra, Josep, Rodrigo Imedio, Esteban, Mellado, Begona
Published in Journal of clinical oncology (20.02.2018)
Published in Journal of clinical oncology (20.02.2018)
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