Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease
Hernández-Alvarez, María Isabel, Sebastián, David, Vives, Sara, Ivanova, Saška, Bartoccioni, Paola, Kakimoto, Pamela, Plana, Natalia, Veiga, Sónia R., Hernández, Vanessa, Vasconcelos, Nuno, Peddinti, Gopal, Adrover, Anna, Jové, Mariona, Pamplona, Reinald, Gordaliza-Alaguero, Isabel, Calvo, Enrique, Cabré, Noemí, Castro, Rui, Kuzmanic, Antonija, Boutant, Marie, Sala, David, Hyotylainen, Tuulia, Orešič, Matej, Fort, Joana, Errasti-Murugarren, Ekaitz, Rodrígues, Cecilia M.P., Orozco, Modesto, Joven, Jorge, Cantó, Carles, Palacin, Manuel, Fernández-Veledo, Sonia, Vendrell, Joan, Zorzano, Antonio
Published in Cell (02.05.2019)
Published in Cell (02.05.2019)
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miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease
Castro, Rui E, Ferreira, Duarte M.S, Afonso, Marta B, Borralho, Pedro M, Machado, Mariana V, Cortez-Pinto, Helena, Rodrigues, Cecília M.P
Published in Journal of hepatology (01.01.2013)
Published in Journal of hepatology (01.01.2013)
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Necroptosis is a key pathogenic event in human and experimental murine models of non-alcoholic steatohepatitis
Afonso, Marta B, Rodrigues, Pedro M, Carvalho, Tânia, Caridade, Marta, Borralho, Paula, Cortez-Pinto, Helena, Castro, Rui E, Rodrigues, Cecília M P
Published in Clinical science (1979) (01.10.2015)
Published in Clinical science (1979) (01.10.2015)
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Bile acids: regulation of apoptosis by ursodeoxycholic acid
Amaral, Joana D., Viana, Ricardo J.S., Ramalho, Rita M., Steer, Clifford J., Rodrigues, Cecília M.P.
Published in Journal of lipid research (01.09.2009)
Published in Journal of lipid research (01.09.2009)
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Glucocorticoid receptor-dependent therapeutic efficacy of tauroursodeoxycholic acid in preclinical models of spinocerebellar ataxia type 3
Duarte-Silva, Sara, Da Silva, Jorge Diogo, Monteiro-Fernandes, Daniela, Costa, Marta Daniela, Neves-Carvalho, Andreia, Raposo, Mafalda, Soares-Cunha, Carina, Correia, Joana S, Nogueira-Goncalves, Gonçalo, Fernandes, Henrique S, Oliveira, Stephanie, Ferreira-Fernandes, Ana Rita, Rodrigues, Fernando, Pereira-Sousa, Joana, Vilasboas-Campos, Daniela, Guerreiro, Sara, Campos, Jonas, Meireles-Costa, Liliana, Rodrigues, Cecilia M.P., Cabantous, Stephanie, Sousa, Sergio F, Lima, Manuela, Teixeira-Castro, Andreia, Maciel, Patricia
Published in The Journal of clinical investigation (01.03.2024)
Published in The Journal of clinical investigation (01.03.2024)
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Necrosome Formation and Necroptosis in Experimental Cholestasis
Afonso, Marta B, Rodrigues, Cecília M P
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2019)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2019)
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Measuring the Impact of Bile Acids on the Membrane Order of Primary Hepatocytes and Isolated Mitochondria by Fluorescence Imaging and Spectroscopy
Sousa, Tânia, Castro, Rui E, Coutinho, Ana, Rodrigues, Cecília M P, Prieto, Manuel, Fernandes, Fábio
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2019)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2019)
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Journal Article
Tauroursodeoxycholic acid suppresses amyloid β-induced synaptic toxicity in vitro and in APP/PS1 mice
Ramalho, Rita M, Nunes, Ana F, Dias, Raquel B, Amaral, Joana D, Lo, Adrian C, D'Hooge, Rudi, Sebastião, Ana M, Rodrigues, Cecilia M.P
Published in Neurobiology of aging (01.02.2013)
Published in Neurobiology of aging (01.02.2013)
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Monoterpene bisindole alkaloids, from the African medicinal plant Tabernaemontana elegans, induce apoptosis in HCT116 human colon carcinoma cells
Mansoor, Tayyab A., Borralho, Pedro M., Dewanjee, Saikat, Mulhovo, Silva, Rodrigues, Cecília M.P., Ferreira, Maria-José U.
Published in Journal of ethnopharmacology (16.09.2013)
Published in Journal of ethnopharmacology (16.09.2013)
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Tauroursodeoxycholic Acid, A Bile Acid, is Neuroprotective in a Transgenic Animal Model of Huntington's Disease
Keene, C. Dirk, Cecilia M.P. Rodrigues, Eich, Tacjana, Chhabra, Manik S., Steer, Clifford J., Low, Walter C.
Published in Proceedings of the National Academy of Sciences - PNAS (06.08.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (06.08.2002)
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The necroptosis-inducing pseudokinase mixed lineage kinase domain-like regulates the adipogenic differentiation of pre-adipocytes
Magusto, Julie, Beaupère, Carine, Afonso, Marta B., Auclair, Martine, Delaunay, Jean-Louis, Soret, Pierre-Antoine, Courtois, Gilles, Aït-Slimane, Tounsia, Housset, Chantal, Jéru, Isabelle, Fève, Bruno, Ratziu, Vlad, Rodrigues, Cecilia M.P., Gautheron, Jérémie
Published in iScience (21.10.2022)
Published in iScience (21.10.2022)
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Targeting the p53 pathway of apoptosis
Amaral, Joana D, Xavier, Joana M, Steer, Clifford J, Rodrigues, Cecília M P
Published in Current pharmaceutical design (01.07.2010)
Published in Current pharmaceutical design (01.07.2010)
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Lytic cell death in metabolic liver disease
Gautheron, Jérémie, Gores, Gregory J., Rodrigues, Cecília M.P.
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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Development Of a Microfluidic Colorectal Cancer Cell Culture System with Integrated Optical Sensors for Rapid Phage Selection
Condelipes, Pedro G.M., Fontes, Pedro M., Nikolaidou, Katerina, Marques, Vanda, Bras, Eduardo J.S., Afonso, Marta B., Rodrigues, Cecilia M.P., Goncalves, Joao, Chu, V., Conde, Joao Pedro
Published in 2020 IEEE Sensors (25.10.2020)
Published in 2020 IEEE Sensors (25.10.2020)
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Conference Proceeding
Cell death targets and potential modulators in Alzheimer's disease
Castro, Rui E, Santos, Maria M M, Glória, Paulo M C, Ribeiro, Carlos J A, Ferreira, Duarte M S, Xavier, Joana M, Moreira, Rui, Rodrigues, Cecília M P
Published in Current pharmaceutical design (01.01.2010)
Published in Current pharmaceutical design (01.01.2010)
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Delivering the promise of miRNA cancer therapeutics
Pereira, Diane M., Rodrigues, Pedro M., Borralho, Pedro M., Rodrigues, Cecília M.P.
Published in Drug discovery today (01.03.2013)
Published in Drug discovery today (01.03.2013)
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A Bile Acid Protects against Motor and Cognitive Deficits and Reduces Striatal Degeneration in the 3-Nitropropionic Acid Model of Huntington's Disease
Keene, C.Dirk, Rodrigues, Cecilia M.P., Eich, Tacjana, Linehan-Stieers, Cheryle, Abt, Anna, Kren, Betsy T., Steer, Clifford J., Low, Walter C.
Published in Experimental neurology (01.10.2001)
Published in Experimental neurology (01.10.2001)
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Conference Proceeding