USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma
Eichhorn, Pieter J A, Rodón, Laura, Gonzàlez-Juncà, Alba, Dirac, Annette, Gili, Magüi, Martínez-Sáez, Elena, Aura, Claudia, Barba, Ignasi, Peg, Vicente, Prat, Aleix, Cuartas, Isabel, Jimenez, Jose, García-Dorado, David, Sahuquillo, Juan, Bernards, Réné, Baselga, José, Seoane, Joan
Published in Nature medicine (01.03.2012)
Published in Nature medicine (01.03.2012)
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TGF-β Receptor Inhibitors Target the CD44(high)/Id1(high) Glioma-Initiating Cell Population in Human Glioblastoma
Anido, Judit, Sáez-Borderías, Andrea, Gonzàlez-Juncà, Alba, Rodón, Laura, Folch, Gerard, Carmona, Maria A, Prieto-Sánchez, Rosa M, Barba, Ignasi, Martínez-Sáez, Elena, Prudkin, Ludmila, Cuartas, Isabel, Raventós, Carolina, Martínez-Ricarte, Francisco, Poca, M Antonia, García-Dorado, David, Lahn, Michael M, Yingling, Jonathan M, Rodón, Jordi, Sahuquillo, Juan, Baselga, José, Seoane, Joan
Published in Cancer cell (14.12.2010)
Published in Cancer cell (14.12.2010)
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USP15 regulates SMURF2 kinetics through C-lobe mediated deubiquitination
Iyengar, Prasanna Vasudevan, Jaynes, Patrick, Rodon, Laura, Lama, Dilraj, Law, Kai Pong, Lim, Yoon Pin, Verma, Chandra, Seoane, Joan, Eichhorn, Pieter Johan Adam
Published in Scientific reports (05.10.2015)
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The CREB coactivator CRTC2 promotes oncogenesis in LKB1-mutant non-small cell lung cancer
Rodón, Laura, Svensson, Robert U, Wiater, Ezra, Chun, Matthew G H, Tsai, Wen-Wei, Eichner, Lillian J, Shaw, Reuben J, Montminy, Marc
Published in Science advances (01.07.2019)
Published in Science advances (01.07.2019)
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Adaptive Transcriptional Responses by CRTC Coactivators in Cancer
Tasoulas, Jason, Rodon, Laura, Kaye, Frederic J, Montminy, Marc, Amelio, Antonio L
Published in Trends in cancer (01.02.2019)
Published in Trends in cancer (01.02.2019)
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Journal Article
TGF-β Receptor Inhibitors Target the CD44high/Id1high Glioma-Initiating Cell Population in Human Glioblastoma
Anido, Judit, Sáez-Borderías, Andrea, Gonzàlez-Juncà, Alba, Rodón, Laura, Folch, Gerard, Carmona, Maria A., Prieto-Sánchez, Rosa M., Barba, Ignasi, Martínez-Sáez, Elena, Prudkin, Ludmila, Cuartas, Isabel, Raventós, Carolina, Martínez-Ricarte, Francisco, Poca, M. Antonia, García-Dorado, David, Lahn, Michael M., Yingling, Jonathan M., Rodón, Jordi, Sahuquillo, Juan, Baselga, José, Seoane, Joan
Published in Cancer cell (14.12.2010)
Published in Cancer cell (14.12.2010)
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Active CREB1 promotes a malignant TGFβ2 autocrine loop in glioblastoma
Rodón, Laura, Gonzàlez-Juncà, Alba, Inda, María del Mar, Sala-Hojman, Ada, Martínez-Sáez, Elena, Seoane, Joan
Published in Cancer discovery (01.10.2014)
Published in Cancer discovery (01.10.2014)
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Abstract 1957: Repotrectinib increases effectiveness of MEK inhibitor trametinib in KRAS mutant cancer models via simultaneous SRC/FAK/JAK2 inhibition
Murray, Brion, Deng, Wei, Zhai, Dayong, Rodon, Laura, Lee, Nathan, Cui, J. Jean
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract 1958: Repotrectinib increases effectiveness of KRAS-G12C inhibitors in KRAS-G12C mutant cancer models via simultaneous SRC/FAK/JAK2 inhibition
Cui, J. Jean, Zhai, Dayong, Deng, Wei, Rodon, Laura, Lee, Nathan, Murray, Brion
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract 1104: Repotrectinib increases effectiveness of MEK inhibitors in KRAS mutant cancer models
Lee, Nathan V., Deng, Wei, Zhai, Dayong, Rodon, Laura, Parra, Ana, Cowell, Jessica, Banisadr, Afsheen, Zhang, Xin, Murray, Brion W.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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The next-generation RET inhibitor TPX-0046 is active in drug-resistant and naïve RET-driven cancer models
Drilon, Alexander E., Zhai, Dayong, Rogers, Evan, Deng, Wei, Zhang, Xin, Ung, Jane, Lee, Dong, Rodon, Laura, Graber, Armin, Zimmerman, Zachary Franklin, Murray, Brion W, Subbiah, Vivek
Published in Journal of clinical oncology (20.05.2020)
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디아릴 매크로시클릭 화합물을 수반하는 병용 요법
LEE NATHAN V, MURRAY BRION W, ZHAI DAYONG, DENG WEI, CUI JINGRONG J, RODON LAURA
Year of Publication 05.10.2022
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Year of Publication 05.10.2022
Patent
Abstract LB-31: USP15 stabilizes the TGF-β receptor I and promotes oncogenesis through the activation of the TGF-β signal in glioblastoma
Eichhorn, Pieter J., Rodon, Laura, Gonzalez-Junca, Alba, Baselga, Jose, Seoane, Joan
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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COMBINATION THERAPY INVOLVING DIARYL MACROCYCLIC COMPOUNDS
LEE, Nathan V, DENG, Wei, MURRAY, Brion W, ZHAI, Dayong, RODON, Laura, CUI, Jingrong J
Year of Publication 14.02.2024
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Year of Publication 14.02.2024
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COMBINATION THERAPY INVOLVING DIARYL MACROCYCLIC COMPOUNDS
Murray, Brion W, Cui, Jingrong J, DENG, Wei, Rodon, Laura, Zhai, Dayong
Year of Publication 01.02.2024
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Year of Publication 01.02.2024
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COMBINATION THERAPY INVOLVING DIARYL MACROCYCLIC COMPOUNDS
DENG, Wei, MURRAY, Brion W, ZHAI, Dayong, RODON, Laura, CUI, Jingrong J
Year of Publication 03.01.2024
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Year of Publication 03.01.2024
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COMBINATION THERAPY INVOLVING DIARYL MACROCYCLIC COMPOUNDS
LEE, Nathan V, DENG, Wei, MURRAY, Brion W, ZHAI, Dayong, RODON, Laura, CUI, Jingrong J
Year of Publication 14.12.2023
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Year of Publication 14.12.2023
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Combination therapy involving diaryl macrocyclic compounds
Murray, Brion W, Cui, Jingrong J, Deng, Wei, Rodon, Laura, Zhai, Dayong, Lee, Nathan V
Year of Publication 06.06.2023
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Year of Publication 06.06.2023
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Combination therapy involving diaryl macrocyclic compounds
Murray, Brion W, Cui, Jingrong J, Deng, Wei, Rodon, Laura, Zhai, Dayong
Year of Publication 23.05.2023
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Year of Publication 23.05.2023
Patent