A niche-dependent myeloid transcriptome signature defines dormant myeloma cells
Khoo, Weng Hua, Ledergor, Guy, Weiner, Assaf, Roden, Daniel L., Terry, Rachael L., McDonald, Michelle M., Chai, Ryan C., De Veirman, Kim, Owen, Katie L., Opperman, Khatora S., Vandyke, Kate, Clark, Justine R., Seckinger, Anja, Kovacic, Natasa, Nguyen, Akira, Mohanty, Sindhu T., Pettitt, Jessica A., Xiao, Ya, Corr, Alexander P., Seeliger, Christine, Novotny, Mark, Lasken, Roger S., Nguyen, Tuan V., Oyajobi, Babatunde O., Aftab, Dana, Swarbrick, Alexander, Parker, Belinda, Hewett, Duncan R., Hose, Dirk, Vanderkerken, Karin, Zannettino, Andrew C.W., Amit, Ido, Phan, Tri Giang, Croucher, Peter I.
Published in Blood (04.07.2019)
Published in Blood (04.07.2019)
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Prostate cancer cell‐intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone
Owen, Katie L, Gearing, Linden J, Zanker, Damien J, Brockwell, Natasha K, Khoo, Weng Hua, Roden, Daniel L, Cmero, Marek, Mangiola, Stefano, Hong, Matthew K, Spurling, Alex J, McDonald, Michelle, Chan, Chia‐Ling, Pasam, Anupama, Lyons, Ruth J, Duivenvoorden, Hendrika M, Ryan, Andrew, Butler, Lisa M, Mariadason, John M, Giang Phan, Tri, Hayes, Vanessa M, Sandhu, Shahneen, Swarbrick, Alexander, Corcoran, Niall M, Hertzog, Paul J, Croucher, Peter I, Hovens, Chris, Parker, Belinda S
Published in EMBO reports (04.06.2020)
Published in EMBO reports (04.06.2020)
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DNA barcoding reveals ongoing immunoediting of clonal cancer populations during metastatic progression and immunotherapy response
Baldwin, Louise A., Bartonicek, Nenad, Yang, Jessica, Wu, Sunny Z., Deng, Niantao, Roden, Daniel L., Chan, Chia-Ling, Al-Eryani, Ghamdan, Zanker, Damien J., Parker, Belinda S., Swarbrick, Alexander, Junankar, Simon
Published in Nature communications (07.11.2022)
Published in Nature communications (07.11.2022)
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Cryopreservation of human cancers conserves tumour heterogeneity for single-cell multi-omics analysis
Wu, Sunny Z, Roden, Daniel L, Al-Eryani, Ghamdan, Bartonicek, Nenad, Harvey, Kate, Cazet, Aurélie S, Chan, Chia-Ling, Junankar, Simon, Hui, Mun N, Millar, Ewan A, Beretov, Julia, Horvath, Lisa, Joshua, Anthony M, Stricker, Phillip, Wilmott, James S, Quek, Camelia, Long, Georgina V, Scolyer, Richard A, Yeung, Bertrand Z, Segara, Davendra, Mak, Cindy, Warrier, Sanjay, Powell, Joseph E, O'Toole, Sandra, Lim, Elgene, Swarbrick, Alexander
Published in Genome medicine (10.05.2021)
Published in Genome medicine (10.05.2021)
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ELF5 modulates the estrogen receptor cistrome in breast cancer
Piggin, Catherine L, Roden, Daniel L, Law, Andrew M K, Molloy, Mark P, Krisp, Christoph, Swarbrick, Alexander, Naylor, Matthew J, Kalyuga, Maria, Kaplan, Warren, Oakes, Samantha R, Gallego-Ortega, David, Clark, Susan J, Carroll, Jason S, Bartonicek, Nenad, Ormandy, Christopher J
Published in PLoS genetics (02.01.2020)
Published in PLoS genetics (02.01.2020)
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ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer
Kalyuga, Maria, Gallego-Ortega, David, Lee, Heather J, Roden, Daniel L, Cowley, Mark J, Caldon, C Elizabeth, Stone, Andrew, Allerdice, Stephanie L, Valdes-Mora, Fatima, Launchbury, Rosalind, Statham, Aaron L, Armstrong, Nicola, Alles, M Chehani, Young, Adelaide, Egger, Andrea, Au, Wendy, Piggin, Catherine L, Evans, Cara J, Ledger, Anita, Brummer, Tilman, Oakes, Samantha R, Kaplan, Warren, Gee, Julia M W, Nicholson, Robert I, Sutherland, Robert L, Swarbrick, Alexander, Naylor, Matthew J, Clark, Susan J, Carroll, Jason S, Ormandy, Christopher J
Published in PLoS biology (01.12.2012)
Published in PLoS biology (01.12.2012)
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A mutation in the viral sensor 2'-5'-oligoadenylate synthetase 2 causes failure of lactation
Oakes, Samantha R, Gallego-Ortega, David, Stanford, Prudence M, Junankar, Simon, Au, Wendy Wing Yee, Kikhtyak, Zoya, von Korff, Anita, Sergio, Claudio M, Law, Andrew M K, Castillo, Lesley E, Allerdice, Stephanie L, Young, Adelaide I J, Piggin, Catherine, Whittle, Belinda, Bertram, Edward, Naylor, Matthew J, Roden, Daniel L, Donovan, Jesse, Korennykh, Alexei, Goodnow, Christopher C, O'Bryan, Moira K, Ormandy, Christopher J
Published in PLoS genetics (08.11.2017)
Published in PLoS genetics (08.11.2017)
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Targeting the Id1-Kif11 Axis in Triple-Negative Breast Cancer Using Combination Therapy
Thankamony, Archana P, Murali, Reshma, Karthikeyan, Nitheesh, Varghese, Binitha Anu, Teo, Wee S, McFarland, Andrea, Roden, Daniel L, Holliday, Holly, Konrad, Christina Valbirk, Cazet, Aurelie, Dodson, Eoin, Yang, Jessica, Baker, Laura A, George, Jason T, Levine, Herbert, Jolly, Mohit Kumar, Swarbrick, Alexander, Nair, Radhika
Published in Biomolecules (Basel, Switzerland) (08.09.2020)
Published in Biomolecules (Basel, Switzerland) (08.09.2020)
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Id Proteins Promote a Cancer Stem Cell Phenotype in Mouse Models of Triple Negative Breast Cancer via Negative Regulation of Robo1
Teo, Wee S, Holliday, Holly, Karthikeyan, Nitheesh, Cazet, Aurélie S, Roden, Daniel L, Harvey, Kate, Konrad, Christina Valbirk, Murali, Reshma, Varghese, Binitha Anu, Thankamony, Archana P, Chan, Chia-Ling, McFarland, Andrea, Junankar, Simon, Ye, Sunny, Yang, Jessica, Nikolic, Iva, Shah, Jaynish S, Baker, Laura A, Millar, Ewan K A, Naylor, Matthew J, Ormandy, Christopher J, Lakhani, Sunil R, Kaplan, Warren, Mellick, Albert S, O'Toole, Sandra A, Swarbrick, Alexander, Nair, Radhika
Published in Frontiers in cell and developmental biology (17.07.2020)
Published in Frontiers in cell and developmental biology (17.07.2020)
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Stromal cell diversity associated with immune evasion in human triple‐negative breast cancer
Wu, Sunny Z, Roden, Daniel L, Wang, Chenfei, Holliday, Holly, Harvey, Kate, Cazet, Aurélie S, Murphy, Kendelle J, Pereira, Brooke, Al‐Eryani, Ghamdan, Bartonicek, Nenad, Hou, Rui, Torpy, James R, Junankar, Simon, Chan, Chia‐Ling, Lam, Chuan En, Hui, Mun N, Gluch, Laurence, Beith, Jane, Parker, Andrew, Robbins, Elizabeth, Segara, Davendra, Mak, Cindy, Cooper, Caroline, Warrier, Sanjay, Forrest, Alistair, Powell, Joseph, O'Toole, Sandra, Cox, Thomas R, Timpson, Paul, Lim, Elgene, Liu, X Shirley, Swarbrick, Alexander
Published in The EMBO journal (01.10.2020)
Published in The EMBO journal (01.10.2020)
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Damage-inducible intragenic demethylation of the human TP53 tumor suppressor gene is associated with transcription from an alternative intronic promoter
Blackburn, James, Roden, Daniel L., Ng, Robert, Wu, Jianmin, Bosman, Alexis, Epstein, Richard J.
Published in Molecular carcinogenesis (01.12.2016)
Published in Molecular carcinogenesis (01.12.2016)
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MicroRNA profiling of the pubertal mouse mammary gland identifies miR-184 as a candidate breast tumour suppressor gene
Phua, Yu Wei, Nguyen, Akira, Roden, Daniel L, Elsworth, Benjamin, Deng, Niantao, Nikolic, Iva, Yang, Jessica, Mcfarland, Andrea, Russell, Roslin, Kaplan, Warren, Cowley, Mark J, Nair, Radhika, Zotenko, Elena, O'Toole, Sandra, Tan, Shi-Xiong, James, David E, Clark, Susan J, Kouros-Mehr, Hosein, Swarbrick, Alexander
Published in Breast cancer research : BCR (13.06.2015)
Published in Breast cancer research : BCR (13.06.2015)
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ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype
Junankar, Simon, Baker, Laura A., Roden, Daniel L., Nair, Radhika, Elsworth, Ben, Gallego-Ortega, David, Lacaze, Paul, Cazet, Aurélie, Nikolic, Iva, Teo, Wee Siang, Yang, Jessica, McFarland, Andrea, Harvey, Kate, Naylor, Matthew J., Lakhani, Sunil R., Simpson, Peter T., Raghavendra, Ashwini, Saunus, Jodi, Madore, Jason, Kaplan, Warren, Ormandy, Christopher, Millar, Ewan K. A., O’Toole, Sandra, Yun, Kyuson, Swarbrick, Alexander
Published in Nature communications (27.03.2015)
Published in Nature communications (27.03.2015)
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ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells
Gallego-Ortega, David, Ledger, Anita, Roden, Daniel L, Law, Andrew M K, Magenau, Astrid, Kikhtyak, Zoya, Cho, Christina, Allerdice, Stephanie L, Lee, Heather J, Valdes-Mora, Fatima, Herrmann, David, Salomon, Robert, Young, Adelaide I J, Lee, Brian Y, Sergio, C Marcelo, Kaplan, Warren, Piggin, Catherine, Conway, James R W, Rabinovich, Brian, Millar, Ewan K A, Oakes, Samantha R, Chtanova, Tatyana, Swarbrick, Alexander, Naylor, Matthew J, O'Toole, Sandra, Green, Andrew R, Timpson, Paul, Gee, Julia M W, Ellis, Ian O, Clark, Susan J, Ormandy, Christopher J
Published in PLoS biology (01.12.2015)
Published in PLoS biology (01.12.2015)
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Mouse Model of Mutated in Colorectal Cancer Gene Deletion Reveals Novel Pathways in Inflammation and Cancer
Currey, Nicola, Jahan, Zeenat, Caldon, C. Elizabeth, Tran, Phuong N, Benthani, Fahad, De Lacavalerie, Penelope, Roden, Daniel L, Gloss, Brian S, Campos, Claudia, Bean, Elaine G, Bullman, Amanda, Reibe-Pal, Saskia, Dinger, Marcel E, Febbraio, Mark A, Clarke, Stephen J, Dahlstrom, Jane E, Kohonen-Corish, Maija R.J
Published in Cellular and molecular gastroenterology and hepatology (01.01.2019)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2019)
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ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells: e1002330
Gallego-Ortega, David, Ledger, Anita, Roden, Daniel L, Law, Andrew MK, Magenau, Astrid, Kikhtyak, Zoya, Cho, Christina, Allerdice, Stephanie L, Lee, Heather J, Valdes-Mora, Fatima, Herrmann, David, Salomon, Robert, Young, Adelaide IJ, Lee, Brian Y, Sergio, C Marcelo, Kaplan, Warren, Piggin, Catherine, Conway, James RW, Rabinovich, Brian, Millar, Ewan KA, Oakes, Samantha R, Chtanova, Tatyana, Swarbrick, Alexander, Naylor, Matthew J, O'Toole, Sandra, Green, Andrew R, Timpson, Paul, Gee, Julia MW, Ellis, Ian O, Clark, Susan J, Ormandy, Christopher J
Published in PLoS biology (01.12.2015)
Published in PLoS biology (01.12.2015)
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Mouse Model of Mutated in Colorectal Cancer Gene Deletion Reveals Novel Pathways in Inflammation and CancerSummary
Nicola Currey, Zeenat Jahan, C. Elizabeth Caldon, Phuong N. Tran, Fahad Benthani, Penelope De Lacavalerie, Daniel L. Roden, Brian S. Gloss, Claudia Campos, Elaine G. Bean, Amanda Bullman, Saskia Reibe-Pal, Marcel E. Dinger, Mark A. Febbraio, Stephen J. Clarke, Jane E. Dahlstrom, Maija R.J. Kohonen-Corish
Published in Cellular and molecular gastroenterology and hepatology (01.01.2019)
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Published in Cellular and molecular gastroenterology and hepatology (01.01.2019)
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