Atomic Structure of PDE4: Insights into Phosphodiesterase Mechanism and Specificity
Xu, Robert X., Hassell, Anne M., Vanderwall, Dana, Lambert, Millard H., Holmes, William D., Luther, Michael A., Rocque, Warren J., Milburn, Michael V., Zhao, Yingdong, Ke, Hengming, Nolte, Robert T.
Published in Science (American Association for the Advancement of Science) (09.06.2000)
Published in Science (American Association for the Advancement of Science) (09.06.2000)
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A comparative analysis of the kinetic mechanism and peptide substrate specificity of human and Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase
Rocque, W.J., McWherter, C.A., Wood, D.C., Gordon, J.I.
Published in The Journal of biological chemistry (15.05.1993)
Published in The Journal of biological chemistry (15.05.1993)
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Kinetic and structural evidence for a sequential ordered Bi Bi mechanism of catalysis by Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase
RUDNICK, D. A, MCWHERTER, C. A, ROCQUE, W. J, LENNON, P. J, GETMAN, D. P, GORDON, J. I
Published in The Journal of biological chemistry (25.05.1991)
Published in The Journal of biological chemistry (25.05.1991)
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Effects of pH on bacterial porin function
Todt, Jill C, Rocque, Warren J, McGroarty, Estelle J
Published in Biochemistry (Easton) (03.11.1992)
Published in Biochemistry (Easton) (03.11.1992)
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Oxindole-Based Inhibitors of Cyclin-Dependent Kinase 2 (CDK2): Design, Synthesis, Enzymatic Activities, and X-ray Crystallographic Analysis
Bramson, H. Neal, Corona, John, Davis, Stephen T, Dickerson, Scott H, Edelstein, Mark, Frye, Stephen V, Gampe, Robert T, Harris, Phil A, Hassell, Anne, Holmes, William D, Hunter, Robert N, Lackey, Karen E, Lovejoy, Brett, Luzzio, Michael J, Montana, Val, Rocque, Warren J, Rusnak, David, Shewchuk, Lisa, Veal, James M, Walker, Duncan H, Kuyper, Lee F
Published in Journal of medicinal chemistry (06.12.2001)
Published in Journal of medicinal chemistry (06.12.2001)
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Human Recombinant Phosphodiesterase 4B2B Binds (R)-Rolipram at a Single Site with Two Affinities
Rocque, Warren J, Tian, Gaochao, Wiseman, Jeffrey S, Holmes, William D, Zajac-Thompson, Irene, Willard, Derril H, Patel, Indravaden R, Wisely, G. Bruce, Clay, William C, Kadwell, Sue H, Hoffman, Christine R, Luther, Michael A
Published in Biochemistry (Easton) (18.11.1997)
Published in Biochemistry (Easton) (18.11.1997)
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Crystal Structure of the Catalytic Domain of the Human Cell Cycle Control Phosphatase, Cdc25A
Fauman, Eric B., Cogswell, John P., Lovejoy, Brett, Rocque, Warren J., Holmes, William, Montana, Valerie G., Piwnica-Worms, Helen, Rink, Martin J., Saper, Mark A.
Published in Cell (15.05.1998)
Published in Cell (15.05.1998)
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Prevention of Chemotherapy-Induced Alopecia in Rats by CDK Inhibitors
Davis, Stephen T., Benson, Bill G., Bramson, H. Neal, Chapman, Dennis E., Dickerson, Scott H., Dold, Karen M., Eberwein, Derek J., Edelstein, Mark, Frye, Stephen V., Gampe, Robert T., Griffin, Robert J., Harris, Philip A., Hassell, Anne M., Holmes, William D., Hunter, Robert N., Knick, Victoria B., Lackey, Karen, Lovejoy, Brett, Luzzio, Michael J., Murray, Doris, Parker, Patricia, Rocque, Warren J., Shewchuk, Lisa, Veal, James M., Walker, Duncan H., Kuyper, Lee F.
Published in Science (American Association for the Advancement of Science) (05.01.2001)
Published in Science (American Association for the Advancement of Science) (05.01.2001)
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Use of Photoactivatable Peptide Substrates of Saccharomyces cerevisiae Myristoyl-CoA:Protein N-Myristoyltransferase (Nmt1p) to Characterize a Myristoyl-CoA-Nmt1p-Peptide Ternary Complex and to Provide Evidence for an Ordered Reaction Mechanism
Rudnick, D A, Rocque, W J, McWherter, C A, Toth, M V, Jackson-Machelski, E, Gordon, J I
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.1993)
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.1993)
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Solution Studies of Recombinant Human Stromal-Cell-Derived Factor-1
Holmes, William D., Consler, Thomas G., Dallas, Walter S., Rocque, Warren J., Willard, Derril H.
Published in Protein expression and purification (01.04.2001)
Published in Protein expression and purification (01.04.2001)
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Identification of Peptides That Inhibit the DNA Binding, trans-Activator, and DNA Replication Functions of the Human Papillomavirus Type 11 E2 Protein
DENG, Su-Jun, PEARCE, Kenneth H, ALEXANDER, Kenneth A, UNDERWOOD, Mark R, DIXON, Eric P, HARTLEY, Kelly A, STANLEY, Thomas B, LOBE, David C, GARVEY, Edward P, KOST, Thomas A, PETTY, Regina L, ROCQUE, Warren J
Published in Journal of Virology (01.03.2004)
Published in Journal of Virology (01.03.2004)
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Phosphorylation of a cAMP-specific phosphodiesterase (HSPDE4B2B) by mitogen-activated protein kinase
Lenhard, J M, Kassel, D B, Rocque, W J, Hamacher, L, Holmes, W D, Patel, I, Hoffman, C, Luther, M
Published in Biochemical journal (15.06.1996)
Published in Biochemical journal (15.06.1996)
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The E1 Helicase of Human Papillomavirus Type 11 Binds to the Origin of Replication with Low Sequence Specificity
Dixon, Eric P., Pahel, Greg L., Rocque, Warren J., Barnes, Julie A., Lobe, David C., Hanlon, Mary H., Alexander, Kenneth A., Chao, Shih-Fong, Lindley, Kathy, Phelps, William C.
Published in Virology (New York, N.Y.) (10.05.2000)
Published in Virology (New York, N.Y.) (10.05.2000)
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Detailed Characterization of a Purified Type 4 Phosphodiesterase, HSPDE4B2B: Differentiation of High- and Low-Affinity (R)-Rolipram Binding
Rocque, Warren J., Holmes, William D., Patel, Indravadan R., Dougherty, Robert W., Ittoop, Olivia, Overton, Laurie, Hoffman, Christine R., Wisely, G.Bruce, Willard, Derril H., Luther, Michael A.
Published in Protein expression and purification (01.03.1997)
Published in Protein expression and purification (01.03.1997)
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Replication-Associated Activities of Purified Human Papillomavirus Type 11 E1 Helicase
Rocque, Warren J., Porter, David J.T., Barnes, Julie A., Dixon, Eric P., Lobe, David C., Su, Jui-Lan, Willard, Derril H., Gaillard, Richard, Condreay, J.Patrick, Clay, William C., Hoffman, Christine R., Overton, Laurie K., Pahel, Greg, Kost, Thomas A., Phelps, William C.
Published in Protein expression and purification (01.03.2000)
Published in Protein expression and purification (01.03.2000)
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Dual Inhibition of Human Type 4 Phosphodiesterase Isostates by (R,R)-(±)-Methyl 3-Acetyl-4-[3-(cyclopentyloxy)-4-methoxyphenyl]-3- methyl-1-pyrrolidinecarboxylate
Tian, Gaochao, Rocque, Warren J, Wiseman, Jeffrey S, Thompson, Irene Z, Holmes, William D, Domanico, Paul L, Stafford, Jeffrey A, Feldman, Paul L, Luther, Michael A
Published in Biochemistry (Easton) (12.05.1998)
Published in Biochemistry (Easton) (12.05.1998)
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