Enabling the formation of native mAb, Fab′ and Fc-conjugates using a bis-disulfide bridging reagent to achieve tunable payload-to-antibody ratios (PARs)
Thoreau, Fabien, Rochet, Léa N. C, Baker, James R, Chudasama, Vijay
Published in Chemical science (Cambridge) (05.04.2023)
Published in Chemical science (Cambridge) (05.04.2023)
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Journal Article
Modular Semisynthetic Approach to Generate T Cell-Dependent Bispecific Constructs from Recombinant IgG1 Antibodies
Shajan, Irene, Rochet, Léa N. C., Tracey, Shannon R., Benazza, Rania, Jackowska, Bianka, Hernandez-Alba, Oscar, Cianférani, Sarah, Scott, Christopher J., van Delft, Floris L., Chudasama, Vijay, Albada, Bauke
Published in Bioconjugate chemistry (16.09.2024)
Published in Bioconjugate chemistry (16.09.2024)
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Journal Article
Rapid Access to Potent Bispecific T Cell Engagers Using Biogenic Tyrosine Click Chemistry
Shajan, Irene, Rochet, Léa N. C., Tracey, Shannon R., Jackowska, Bianka, Benazza, Rania, Hernandez-Alba, Oscar, Cianférani, Sarah, Scott, Christopher J., van Delft, Floris L., Chudasama, Vijay, Albada, Bauke
Published in Bioconjugate chemistry (20.12.2023)
Published in Bioconjugate chemistry (20.12.2023)
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A novel thiol-labile cysteine protecting group for peptide synthesis based on a pyridazinedione (PD) scaffold
Spears, Richard J, McMahon, Clíona, Shamsabadi, Monika, Bahou, Calise, Thanasi, Ioanna A, Rochet, Léa N. C, Forte, Nafsika, Thoreau, Fabien, Baker, James R, Chudasama, Vijay
Published in Chemical communications (Cambridge, England) (13.01.2022)
Published in Chemical communications (Cambridge, England) (13.01.2022)
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Journal Article
Hydrogel Cross-Linking via Thiol-Reactive Pyridazinediones
Bahou, Calise, Spears, Richard J., Ramírez Rosales, Angela M., Rochet, Léa N. C., Barber, Lydia J., Stankevich, Ksenia S., Miranda, Juliana F., Butcher, Tobias C., Kerrigan, Adam M., Lazarov, Vlado K., Grey, William, Chudasama, Vijay, Spicer, Christopher D.
Published in Biomacromolecules (13.11.2023)
Published in Biomacromolecules (13.11.2023)
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Journal Article
Macrocyclic Dual‐Locked “Turn‐On” Drug for Selective and Traceless Release in Cancer Cells
Schauenburg, Dominik, Gao, Bingjie, Rochet, Léa N. C., Schüler, Darijan, Coelho, Jaime A. S., Ng, David Y. W., Chudasama, Vijay, Kuan, Seah Ling, Weil, Tanja
Published in Angewandte Chemie International Edition (24.04.2024)
Published in Angewandte Chemie International Edition (24.04.2024)
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Journal Article
The BMI1 polycomb protein represses cyclin G2-induced autophagy to support proliferation in chronic myeloid leukemia cells
Mourgues, L, Imbert, V, Nebout, M, Colosetti, P, Neffati, Z, Lagadec, P, Verhoeyen, E, Peng, C, Duprez, E, Legros, L, Rochet, N, Maguer-Satta, V, Nicolini, F-E, Mary, D, Peyron, J-F
Published in Leukemia (01.10.2015)
Published in Leukemia (01.10.2015)
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Journal Article
Use of pyridazinediones for tuneable and reversible covalent cysteine modification applied to peptides, proteins and hydrogels
Rochet, Léa N. C, Bahou, Calise, Wojciechowski, Jonathan P, Koutsopetras, Ilias, Britton, Phyllida, Spears, Richard J, Thanasi, Ioanna A, Shao, Baihao, Zhong, Lisha, Bu ar, Dejan-Krešimir, Aliev, Abil E, Porter, Michael J, Stevens, Molly M, Baker, James R, Chudasama, Vijay
Published in Chemical science (Cambridge) (06.12.2023)
Published in Chemical science (Cambridge) (06.12.2023)
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Journal Article
Modular Chemical Construction of IgG-like Mono- and Bispecific Synthetic Antibodies (SynAbs)
Thoreau, Fabien, Szijj, Peter A., Greene, Michelle K., Rochet, Léa N. C., Thanasi, Ioanna A., Blayney, Jaine K., Maruani, Antoine, Baker, James R., Scott, Christopher J., Chudasama, Vijay
Published in ACS central science (22.03.2023)
Published in ACS central science (22.03.2023)
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Journal Article
Modular Synthesis of Semiconducting Graft Copolymers to Achieve “Clickable” Fluorescent Nanoparticles with Long Circulation and Specific Cancer Targeting
Creamer, Adam, Fiego, Alessandra Lo, Agliano, Alice, Prados‐Martin, Lino, Høgset, Håkon, Najer, Adrian, Richards, Daniel A., Wojciechowski, Jonathan P., Foote, James E. J., Kim, Nayoung, Monahan, Amy, Tang, Jiaqing, Shamsabadi, André, Rochet, Léa N. C., Thanasi, Ioanna A., Ballina, Laura R., Rapley, Charlotte L., Turnock, Stephen, Love, Elizabeth A., Bugeon, Laurence, Dallman, Margaret J., Heeney, Martin, Kramer‐Marek, Gabriela, Chudasama, Vijay, Fenaroli, Federico, Stevens, Molly M.
Published in Advanced materials (Weinheim) (01.05.2024)
Published in Advanced materials (Weinheim) (01.05.2024)
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Journal Article
Whole-Abdominal Irradiation Using Intensity Modulated Radiation Therapy for Select Patients With Regionally Advanced or Recurrent Uterine Cancer
Russo, A.L, Turcotte, J.C, Rochet, N, Russell, A.H
Published in International journal of radiation oncology, biology, physics (01.11.2015)
Published in International journal of radiation oncology, biology, physics (01.11.2015)
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Journal Article
Molecular effects of gallium on osteoclastic differentiation of mouse and human monocytes
Verron, E., Loubat, A., Carle, G.F., Vignes-Colombeix, C., Strazic, I., Guicheux, J., Rochet, N., Bouler, J.M., Scimeca, J.C.
Published in Biochemical pharmacology (01.03.2012)
Published in Biochemical pharmacology (01.03.2012)
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A silanized hydroxypropyl methylcellulose hydrogel for the three-dimensional culture of chondrocytes
Vinatier, C., Magne, D., Weiss, P., Trojani, C., Rochet, N., Carle, G.F., Vignes-Colombeix, C., Chadjichristos, C., Galera, P., Daculsi, G., Guicheux, J.
Published in Biomaterials (01.11.2005)
Published in Biomaterials (01.11.2005)
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Journal Article
Consolidative Whole Abdomen Radiation Therapy After Surgery and Carboplatin-Taxol-based Chemotherapy for Advanced Epithelial Uterine Endometrial Malignancy: Feasibility and Clinical Outcomes
Rochet, N, Kahn, R.S, Niemierko, A, Delaney, T.F, Russell, A.H
Published in International journal of radiation oncology, biology, physics (01.11.2012)
Published in International journal of radiation oncology, biology, physics (01.11.2012)
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Journal Article
Multicriteria Optimization in Intensity Modulated Radiation Therapy Treatment Planning for Large Target Volumes: First Experience With Whole Abdomen Radiation Therapy
Rochet, N, Russell, A.H, Jee, K.K, Bortfeld, T.R, Craft, D.L
Published in International journal of radiation oncology, biology, physics (01.11.2012)
Published in International journal of radiation oncology, biology, physics (01.11.2012)
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Journal Article
Synthesis and Characterization of Biomimetic Strontium Substituted Carbonated Calcium-Deficient Hydroxyapatite Deposited on Carbon Fiber Cloths
Bonnamy, S., Picard, Q., Olivier, Florian, Delpeux, S., Fayon, F., Rochet, N., Chancolon, J., Warmont, F.
Published in Key engineering materials (01.11.2017)
Published in Key engineering materials (01.11.2017)
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Journal Article
Human adipose tissue-derived multipotent stem cells differentiate in vitro and in vivo into osteocyte-like cells
Elabd, Christian, Chiellini, Chiara, Massoudi, Ali, Cochet, Olivia, Zaragosi, Laure-Emmanuelle, Trojani, Christophe, Michiels, Jean-François, Weiss, Pierre, Carle, Georges, Rochet, Nathalie, Dechesne, Claude A., Ailhaud, Gérard, Dani, Christian, Amri, Ez-Zoubir
Published in Biochemical and biophysical research communications (21.09.2007)
Published in Biochemical and biophysical research communications (21.09.2007)
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Journal Article
Advances in Whole Abdominal Irradiation: What Protons, VMAT, and IMRT Using Multicriteria Optimization Can Offer
Rochet, N, Batin, E, Depauw, N, Jee, K, Kooy, H.M, Khan, F.H, Paetzold, P.J, Russell, A.H, Bortfeld, T.R, Craft, D.L
Published in International journal of radiation oncology, biology, physics (01.10.2013)
Published in International journal of radiation oncology, biology, physics (01.10.2013)
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Journal Article
Deep Inspiration Breath-Hold Technique in Left-Sided Breast Cancer Radiation Therapy: Evaluating Cardiac Contact Distance as a Predictor of Cardiac Exposure
Rochet, N, Drake, J.I, Harrington, K, Wolfgang, J.A, Napolitano, B, Sadek, B.T, Shenouda, M.N, Keruakous, A.R, Niemierko, A, Taghian, A
Published in International journal of radiation oncology, biology, physics (01.10.2013)
Published in International journal of radiation oncology, biology, physics (01.10.2013)
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