Opicapone as an adjunct to levodopa in patients with Parkinson's disease and end-of-dose motor fluctuations: a randomised, double-blind, controlled trial
Ferreira, Joaquim J, Prof, Lees, Andrew, Prof, Rocha, José-Francisco, BSc, Poewe, Werner, Prof, Rascol, Olivier, Prof, Soares-da-Silva, Patrício, Prof
Published in Lancet neurology (01.02.2016)
Published in Lancet neurology (01.02.2016)
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Effect of Opicapone on Levodopa Pharmacokinetics in Patients with Fluctuating Parkinson's Disease
Ferreira, Joaquim J., Poewe, Werner, Rascol, Olivier, Stocchi, Fabrizio, Antonini, Angelo, Moreira, Joana, Guimarães, Bruno, Rocha, José‐Francisco, Soares‐da‐Silva, Patrício
Published in Movement disorders (01.11.2022)
Published in Movement disorders (01.11.2022)
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Opicapone as Adjunct to Levodopa Therapy in Patients With Parkinson Disease and Motor Fluctuations: A Randomized Clinical Trial
Lees, Andrew J, Ferreira, Joaquim, Rascol, Olivier, Poewe, Werner, Rocha, José-Francisco, McCrory, Michelle, Soares-da-Silva, Patricio
Published in JAMA neurology (01.02.2017)
Published in JAMA neurology (01.02.2017)
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Safety, Tolerability, and Pharmacokinetics of FAAH Inhibitor BIA 10‐2474: A Double‐Blind, Randomized, Placebo‐Controlled Study in Healthy Volunteers
Rocha, José‐Francisco, Santos, Ana, Gama, Helena, Moser, Paul, Falcão, Amílcar, Pressman, Peter, Wallace Hayes, A., Soares‐da‐Silva, Patricio
Published in Clinical pharmacology and therapeutics (01.02.2022)
Published in Clinical pharmacology and therapeutics (01.02.2022)
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Journal Article
Pharmacokinetic and safety profile of trans-resveratrol in a rising multiple-dose study in healthy volunteers
Almeida, Luis, Vaz-da-Silva, Manuel, Falcão, Amílcar, Soares, Eva, Costa, Raquel, Loureiro, Ana I, Fernandes-Lopes, Carlos, Rocha, José-Francisco, Nunes, Teresa, Wright, Lyndon, Soares-da-Silva, Patrício
Published in Molecular nutrition & food research (01.05.2009)
Published in Molecular nutrition & food research (01.05.2009)
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OFF-times before, during, and after nighttime sleep periods in Parkinson's disease patients with motor fluctuations and the effects of opicapone: A post hoc analysis of diary data from BIPARK-1 and -2
Hauser, Robert A., Videnovic, Aleksandar, Soares-da-Silva, Patrício, Liang, Grace S., Olson, Kurt, Jen, Eric, Rocha, José-Francisco, Klepitskaya, Olga
Published in Parkinsonism & related disorders (01.06.2024)
Published in Parkinsonism & related disorders (01.06.2024)
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Efficacy and safety of eslicarbazepine acetate as adjunctive therapy for refractory focal-onset seizures in children: A double-blind, randomized, placebo-controlled, parallel-group, multicenter, phase-III clinical trial
Kirkham, Fenella, Auvin, Stéphane, Moreira, Joana, Gama, Helena, Falcão, Amílcar C., Rocha, José-Francisco, Soares-da-Silva, Patrício
Published in Epilepsy & behavior (01.04.2020)
Published in Epilepsy & behavior (01.04.2020)
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Steady‐state plasma and cerebrospinal fluid pharmacokinetics and tolerability of eslicarbazepine acetate and oxcarbazepine in healthy volunteers
Nunes, Teresa, Rocha, José Francisco, Falcão, Amílcar, Almeida, Luis, Soares‐da‐Silva, Patrício
Published in Epilepsia (Copenhagen) (01.01.2013)
Published in Epilepsia (Copenhagen) (01.01.2013)
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Effect of opicapone and entacapone upon levodopa pharmacokinetics during three daily levodopa administrations
Rocha, José-Francisco, Falcão, Amílcar, Santos, Ana, Pinto, Roberto, Lopes, Nelson, Nunes, Teresa, Wright, Lyndon C., Vaz-da-Silva, Manuel, Soares-da-Silva, Patrício
Published in European journal of clinical pharmacology (01.09.2014)
Published in European journal of clinical pharmacology (01.09.2014)
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Concerns Regarding Opicapone as Adjunct to Levodopa Therapy-Reply
Lees, Andrew J, Rocha, José-Francisco, Soares-da-Silva, Patricio
Published in JAMA neurology (01.07.2017)
Published in JAMA neurology (01.07.2017)
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The Added Benefit of Opicapone When Used Early in Parkinson's Disease Patients With Levodopa-Induced Motor Fluctuations: A Post-hoc Analysis of BIPARK-I and -II
Rocha, José-Francisco, Ebersbach, Georg, Lees, Andrew, Tolosa, Eduardo, Ferreira, Joaquim J., Poewe, Werner, Rascol, Olivier, Stocchi, Fabrizio, Antonini, Angelo, Magalhães, Diogo, Gama, Helena, Soares-da-Silva, Patrício
Published in Frontiers in neurology (05.11.2021)
Published in Frontiers in neurology (05.11.2021)
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Journal Article
Effect of opicapone multiple‐dose regimens on levodopa pharmacokinetics
Rocha, José‐Francisco, Sicard, Éric, Fauchoux, Nicolas, Falcão, Amílcar, Santos, Ana, Loureiro, Ana I., Pinto, Roberto, Bonifácio, Maria João, Nunes, Teresa, Almeida, Luís, Soares‐da‐Silva, Patrício
Published in British journal of clinical pharmacology (01.03.2017)
Published in British journal of clinical pharmacology (01.03.2017)
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Journal Article
Pharmacokinetics of trans-resveratrol following repeated administration in healthy elderly and young subjects
Nunes, Teresa, Almeida, Luis, Rocha, José-Francisco, Falcão, Amílcar, Fernandes-Lopes, Carlos, Loureiro, Ana I, Wright, Lyndon, Vaz-da-Silva, M, Soares-da-Silva, Patrício
Published in Journal of clinical pharmacology (01.12.2009)
Published in Journal of clinical pharmacology (01.12.2009)
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Safety, Tolerability and Efficacy of Eslicarbazepine Acetate as Adjunctive Therapy in Patients Aged ≥ 65 Years with Focal Seizures
Costa, Raquel, Steinhoff, Bernhard, Gama, Helena, Ikedo, Fábio, Rocha, José-Francisco, Soares-da-Silva, Patrício
Published in Drugs & aging (01.12.2018)
Published in Drugs & aging (01.12.2018)
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Journal Article
The safety/tolerability of opicapone when used early in Parkinson's disease patients with levodopa-induced motor fluctuations: A post-hoc analysis of BIPARK-I and II
Rocha, José-Francisco, Ebersbach, Georg, Lees, Andrew, Tolosa, Eduardo, Ferreira, Joaquim J., Poewe, Werner, Rascol, Olivier, Stocchi, Fabrizio, Antonini, Angelo, Magalhães, Diogo, Gama, Helena, Soares-da-Silva, Patrício
Published in Frontiers in neurology (23.08.2022)
Published in Frontiers in neurology (23.08.2022)
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Journal Article
Pooled efficacy and safety of eslicarbazepine acetate as add‐on treatment in patients with focal‐onset seizures: Data from four double‐blind placebo‐controlled pivotal phase III clinical studies
Elger, Christian, Koepp, Mathias, Trinka, Eugen, Villanueva, Vicente, Chaves, João, Ben‐Menachen, Elinor, Kowacs, Pedro A., Gil‐Nagel, António, Moreira, Joana, Gama, Helena, Rocha, José‐Francisco, Soares‐da‐Silva, Patrício
Published in CNS neuroscience & therapeutics (01.12.2017)
Published in CNS neuroscience & therapeutics (01.12.2017)
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Opicapone to Treat Early Wearing‐off in Parkinson's Disease Patients: The Korean ADOPTION Trial
Lee, Jee‐Young, Ma, Hyeo‐il, Ferreira, Joaquim J., Rocha, José‐Francisco, Sung, Young Hee, Song, In‐Uk, Ahn, Tae‐Beom, Kwon, Do Young, Cheon, Sang‐Myung, Kim, Jong‐Min, Lee, Chong Sik, Lee, Phil Hyu, Park, Jeong‐Ho, Lee, Jae‐Hyeok, Park, Mee Young, Kim, Sang Jin, Baik, Jong Sam, Choi, Seong‐Min, Shin, Hae‐Won, Lee, Ho‐Won, Kang, Suk Yun, Jeon, Beomseok
Published in Movement disorders clinical practice (Hoboken, N.J.) (01.06.2024)
Published in Movement disorders clinical practice (Hoboken, N.J.) (01.06.2024)
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