Tyrosine Kinase Inhibitors. 18. 6-Substituted 4-Anilinoquinazolines and 4-Anilinopyrido[3,4-d]pyrimidines as Soluble, Irreversible Inhibitors of the Epidermal Growth Factor Receptor
Smaill, Jeff B, Showalter, H. D. Hollis, Zhou, Hairong, Bridges, Alexander J, McNamara, Dennis J, Fry, David W, Nelson, James M, Sherwood, Veronika, Vincent, Patrick W, Roberts, Bill J, Elliott, William L, Denny, William A
Published in Journal of medicinal chemistry (01.02.2001)
Published in Journal of medicinal chemistry (01.02.2001)
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Synthesis and Tyrosine Kinase Inhibitory Activity of a Series of 2-Amino-8H-pyrido[2,3-d]pyrimidines: Identification of Potent, Selective Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitors
Boschelli, Diane H, Wu, Zhipei, Klutchko, Sylvester R, Showalter, H. D. Hollis, Hamby, James M, Lu, Gina H, Major, Terry C, Dahring, Tawny K, Batley, Brian, Panek, Robert L, Keiser, Joan, Hartl, Brian G, Kraker, Alan J, Klohs, Wayne D, Roberts, Bill J, Patmore, Sandra, Elliott, William L, Steinkampf, Randy, Bradford, Laura A, Hallak, Hussein, Doherty, Annette M
Published in Journal of medicinal chemistry (22.10.1998)
Published in Journal of medicinal chemistry (22.10.1998)
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Tyrosine Kinase Inhibitors. 13. Structure−Activity Relationships for Soluble 7-Substituted 4-[(3-Bromophenyl)amino]pyrido[4,3-d]pyrimidines Designed as Inhibitors of the Tyrosine Kinase Activity of the Epidermal Growth Factor Receptor
Thompson, Andrew M, Murray, Donna K, Elliott, William L, Fry, David W, Nelson, James A, Hollis Showalter, H. D, Roberts, Bill J, Vincent, Patrick W, Denny, William A
Published in Journal of medicinal chemistry (21.11.1997)
Published in Journal of medicinal chemistry (21.11.1997)
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3-(3,5-Dimethoxyphenyl)-1,6-naphthyridine-2,7-diamines and Related 2-Urea Derivatives Are Potent and Selective Inhibitors of the FGF Receptor-1 Tyrosine Kinase
Thompson, Andrew M, Connolly, Cleo J. C, Hamby, James M, Boushelle, Stacey, Hartl, Brian G, Amar, Aneesa M, Kraker, Alan J, Driscoll, Denise L, Steinkampf, Randall W, Patmore, Sandra J, Vincent, Patrick W, Roberts, Bill J, Elliott, William L, Klohs, Wayne, Leopold, Wilbur R, Showalter, H. D. Hollis, Denny, William A
Published in Journal of medicinal chemistry (02.11.2000)
Published in Journal of medicinal chemistry (02.11.2000)
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Tyrosine Kinase Inhibitors. 6. Structure−Activity Relationships among N- and 3-Substituted 2,2‘-Diselenobis(1H-indoles) for Inhibition of Protein Tyrosine Kinases and Comparative in Vitro and in Vivo Studies against Selected Sulfur Congeners
Showalter, H. D. Hollis, Sercel, Anthony D, Leja, Boguslawa M, Wolfangel, Craig D, Ambroso, Linda A, Elliott, William L, Fry, David W, Kraker, Alan J, Howard, Curtis T, Lu, Gina H, Moore, Charles W, Nelson, James M, Roberts, Bill J, Vincent, Patrick W, Denny, William A, Thompson, Andrew M
Published in Journal of medicinal chemistry (14.02.1997)
Published in Journal of medicinal chemistry (14.02.1997)
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Journal Article
Synthesis and Tyrosine Kinase Inhibitory Activity of a Series of 2-Amino-8 H -pyrido[2,3- d ]pyrimidines: Identification of Potent, Selective Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitors
Boschelli, Diane H., Wu, Zhipei, Klutchko, Sylvester R., Showalter, H. D. Hollis, Hamby, James M., Lu, Gina H., Major, Terry C., Dahring, Tawny K., Batley, Brian, Panek, Robert L., Keiser, Joan, Hartl, Brian G., Kraker, Alan J., Klohs, Wayne D., Roberts, Bill J., Patmore, Sandra, Elliott, William L., Steinkampf, Randy, Bradford, Laura A., Hallak, Hussein, Doherty, Annette M.
Published in Journal of medicinal chemistry (01.10.1998)
Published in Journal of medicinal chemistry (01.10.1998)
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Journal Article