Evidence for a novel, effective approach to targeting carcinoma catabolism exploiting the first-in-class, anti-cancer mitochondrial drug, CPI-613
Guardado Rivas, Moises O, Stuart, Shawn D, Thach, Daniel, Dahan, Michael, Shorr, Robert, Zachar, Zuzana, Bingham, Paul M
Published in PloS one (08.06.2022)
Published in PloS one (08.06.2022)
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Non-redox-active lipoate derivates disrupt cancer cell mitochondrial metabolism and are potent anticancer agents in vivo
ZACHAR, Zuzana, MARECEK, James, LEE, King, RODRIGUEZ, Robert, SHORR, Robert, BINGHAM, Paul M, MATURO, Claudia, GUPTA, Sunita, STUART, Shawn D, HOWELL, Katy, SCHAUBLE, Alexandra, LEM, Joanna, PIRAMZADIAN, Arin, KARNIK, Sameer
Published in Journal of molecular medicine (Berlin, Germany) (01.11.2011)
Published in Journal of molecular medicine (Berlin, Germany) (01.11.2011)
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Molecular cloning and expression of the major protein kinase C substrate of platelets
Tyers, M, Rachubinski, R A, Stewart, M I, Varrichio, A M, Shorr, R G, Haslam, R J, Harley, C B
Published in Nature (London) (02.06.1988)
Published in Nature (London) (02.06.1988)
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Advances in lipid nanodispersions for parenteral drug delivery and targeting
Constantinides, Panayiotis P., Chaubal, Mahesh V., Shorr, Robert
Published in Advanced drug delivery reviews (17.03.2008)
Published in Advanced drug delivery reviews (17.03.2008)
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Conference Proceeding
Non-redox-active lipoate derivates disrupt cancer cell mitochondrial metabolism and are potent anticancer agents in vivo
Zachar, Zuzana, Marecek, James, Maturo, Claudia, Gupta, Sunita, Stuart, Shawn D., Howell, Katy, Schauble, Alexandra, Lem, Joanna, Piramzadian, Arin, Karnik, Sameer, Lee, King, Rodriguez, Robert, Shorr, Robert, Bingham, Paul M.
Published in Journal of molecular medicine (Berlin, Germany) (01.11.2011)
Published in Journal of molecular medicine (Berlin, Germany) (01.11.2011)
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Abstract 4861: Initial preclinical evaluation of a novel inhibitor of mitochondrial metabolism against prostate cancer
Sai, Kiran K. Solingapuram, Sattiraju, Anirudh, Zachar, Zuzana, Dahan, Michael S., Shorr, Robert, Pardee, Timothy S., Bingham, Paul M., Mintz, Akiva
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Physiological Effect of Polyethylene Glycol Conjugation on Stroma-Free Bovine Hemoglobin in the Conscious Dog After Partial Exchange Transfusion
Conover, Charles D., Lejeune, Laura, Shum, Kwok, Gilbert, Carl, Shorr, Robert G. L.
Published in Artificial organs (01.05.1997)
Published in Artificial organs (01.05.1997)
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Evidence for a novel, effective approach to targeting carcinoma catabolism exploiting the first-in-class, anti-cancer mitochondrial drug, CPI-613
Moises O Guardado Rivas, Shawn D Stuart, Daniel Thach, Michael Dahan, Robert Shorr, Zuzana Zachar, Paul M Bingham
Published in PloS one (01.01.2022)
Published in PloS one (01.01.2022)
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Poly(ethylene glycol) Fluorescent Linkers
Pendri, Annapurna, Martinez, Anthony, Xia, Jing, Shorr, Robert G. L, Greenwald, Richard B
Published in Bioconjugate chemistry (01.09.1995)
Published in Bioconjugate chemistry (01.09.1995)
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Randomized, placebo-controlled trial of trimethobenzamide to control nausea and vomiting during initiation and continued treatment with subcutaneous apomorphine injection
Hauser, Robert A, Isaacson, Stuart, Clinch, Thomas
Published in Parkinsonism & related disorders (01.11.2014)
Published in Parkinsonism & related disorders (01.11.2014)
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Abstract 1122: Lipoic acid analogs induce ROS, leading to potent mitochondrial enzyme inhibition, metabolic dysfunction and cell death in tumor cells
Stuart, Shawn D., Zachar, Zuzana, Gupta, Sunita, Rodriguez, Robert, Shorr, Robert, Bingham, Paul M.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Translational assessment of mitochondrial dysfunction of pancreatic cancer from in vitro gene microarray and animal efficacy studies, to early clinical studies, via the novel tumor-specific anti-mitochondrial agent, CPI-613
Lee, King C, Maturo, Claudia, Perera, Candida N, Luddy, John, Rodriguez, Robert, Shorr, Robert
Published in Annals of translational medicine (01.09.2014)
Published in Annals of translational medicine (01.09.2014)
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Nanomedicine-nanoemulsion formulation improves safety and efficacy of the anti-cancer drug paclitaxel according to preclinical assessment
Lee, King C, Maturo, Claudia, Rodriguez, Robert, Nguyen, Hoang-Lan, Shorr, Robert
Published in Journal of nanoscience and nanotechnology (01.08.2011)
Published in Journal of nanoscience and nanotechnology (01.08.2011)
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An Efficient, Economical Synthesis of the Novel Anti-tumor Agent CPI-613
Gibson, Frank S, Gupta, Deepak, Shorr, Robert, Rodriguez, Robert
Published in Organic process research & development (15.07.2011)
Published in Organic process research & development (15.07.2011)
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