Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk
Gaudet, Mia M, Kuchenbaecker, Karoline B, Vijai, Joseph, Klein, Robert J, Kirchhoff, Tomas, McGuffog, Lesley, Barrowdale, Daniel, Dunning, Alison M, Lee, Andrew, Dennis, Joe, Healey, Sue, Dicks, Ed, Soucy, Penny, Sinilnikova, Olga M, Pankratz, Vernon S, Wang, Xianshu, Eldridge, Ronald C, Tessier, Daniel C, Vincent, Daniel, Bacot, Francois, Hogervorst, Frans B L, Peock, Susan, Stoppa-Lyonnet, Dominique, Peterlongo, Paolo, Schmutzler, Rita K, Nathanson, Katherine L, Piedmonte, Marion, Singer, Christian F, Thomassen, Mads, Hansen, Thomas v O, Neuhausen, Susan L, Blanco, Ignacio, Greene, Mark H, Garber, Judith, Weitzel, Jeffrey N, Andrulis, Irene L, Goldgar, David E, D'Andrea, Emma, Caldes, Trinidad, Nevanlinna, Heli, Osorio, Ana, van Rensburg, Elizabeth J, Arason, Adalgeir, Rennert, Gad, van den Ouweland, Ans M W, van der Hout, Annemarie H, Kets, Carolien M, Aalfs, Cora M, Wijnen, Juul T, Ausems, Margreet G E M, Frost, Debra, Ellis, Steve, Fineberg, Elena, Platte, Radka, Evans, D Gareth, Jacobs, Chris, Adlard, Julian, Tischkowitz, Marc, Porteous, Mary E, Damiola, Francesca, Golmard, Lisa, Barjhoux, Laure, Longy, Michel, Belotti, Muriel, Ferrer, Sandra Fert, Mazoyer, Sylvie, Spurdle, Amanda B, Manoukian, Siranoush, Barile, Monica, Genuardi, Maurizio, Arnold, Norbert, Meindl, Alfons, Sutter, Christian, Wappenschmidt, Barbara, Domchek, Susan M, Pfeiler, Georg, Friedman, Eitan, Jensen, Uffe Birk, Robson, Mark, Shah, Sohela, Lazaro, Conxi, Mai, Phuong L, Benitez, Javier, Southey, Melissa C, Schmidt, Marjanka K, Fasching, Peter A, Peto, Julian, Humphreys, Manjeet K, Wang, Qin, Michailidou, Kyriaki, Sawyer, Elinor J, Burwinkel, Barbara, Guénel, Pascal, Bojesen, Stig E, Milne, Roger L, Brenner, Hermann, Lochmann, Magdalena, Aittomäki, Kristiina, Dörk, Thilo, Margolin, Sara
Published in PLoS genetics (01.03.2013)
Published in PLoS genetics (01.03.2013)
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Abstract 2566: Comprehensive analysis to identify functional basis of prostate cancer risk SNPs
Middha, Mridu, Xu, Xing, Vaananen, Riina-Minna, Hayes, James, Taimen, Pekka, Gao, Xiaoni, Lilja, Hans G., Pettersson, Kim, Klein, Robert J.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract 1297: Genetic reclassification of prostate-specific antigen levels for personalized prostate cancer screening
Graff, Rebecca E., Hoffmann, Thomas J., Passarelli, Michael N., Emami, Nima C., Sakoda, Lori C., Jorgenson, Eric, Habel, Laurel A., Shan, Jun, Ranatunga, Dilrini K., Quesenberry, Charles P., Chao, Chun R., Ghai, Nirupa R., Aaronson, David, Presti, Joseph, Nordström, Tobias, Wang, Zhaoming, Berndt, Sonja I., Chanock, Stephen J., Mosley, Jonathan D., Klein, Robert J., Middha, Mridu, Lilja, Hans, Melander, Olle, Kvale, Mark N., Kwok, Pui-Yan, Schaefer, Catherine, Risch, Neil, Eeden, Stephen K. Van Den, Witte, John S.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Breast cancer risk prediction using the novel germ-line signatures in epigenome regulatory pathways
Adaniel, Christina, Rendleman, Justin, Smith, Julia Anne, Klein, Robert J., Schnabel, Freya Ruth, Shao, Yongzhao, Offit, Kenneth, Kirchhoff, Tomas
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
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Abstract 1441: Genetic determinants of PSA levels improve prostate cancer screening
Kachuri, Linda, Graff, Rebecca E., Berndt, Sonja I., Machiela, Mitchell, Freedman, Neal D., Chanock, Stephen J., Shelley, John P., Schaffer, Kerry, Mosley, Jonathan D., Goodman, Phyllis J., Till, Cathee, Thompson, Ian, Klein, Robert J., Van Den Eeden, Stephen K., Hoffmann, Thomas J., Witte, John S.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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613 VALIDATION AND CLINICAL ASSOCIATIONS OF RECENTLY REPORTED RCC SUSCEPTIBILITY LOCI
Hakimi, A Ari, Ostrovnaya, Irina, Stratton, Kelly, Hsieh, James J, Coleman, Jonathan, Russo, Paul, Klein, Robert J
Published in The Journal of urology (01.04.2013)
Published in The Journal of urology (01.04.2013)
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Genetic variation in KLK2 and KLK3 is associated with levels of hK2 and PSA in seminal plasma and in serum in young men
Sävblom, Charlotta, Halldén, Christer, Cronin, Angel M., Säll, Torbjörn, Savage, Caroline, Vertosick, Emily A., Klein, Robert J., Giwercman, Aleksander, Lilja, Hans
Published in Clinical chemistry (Baltimore, Md.) (22.11.2013)
Published in Clinical chemistry (Baltimore, Md.) (22.11.2013)
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Clinical and preclinical evaluation of taxane sensitivity in gastric cancer (GC): Relevance of GC histology
Galletti, Giuseppe, Cleveland, Kyle, Matov, Alex, Hayes, James E., Klein, Robert J., Hassane, Duane C., Nicacio, Leonardo V., Giannakakou, Paraskevi, Shah, Manish A.
Published in Journal of clinical oncology (01.02.2013)
Published in Journal of clinical oncology (01.02.2013)
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Validation and genomic interrogation of the MET variant rs11762213 as a predictor of adverse outcomes in clear cell renal cell carcinoma
Hakimi, A. Ari, Ostrovnaya, Irina, Jacobsen, Anders, Coleman, Jonathan A., Russo, Paul, Mano, Roy, Sankin, Alexander, Motzer, Robert John, Purdue, Mark, Pomerantz, Mark, Freedman, Matthew L, Choueiri, Toni K., Hsieh, James, Klein, Robert J.
Published in Journal of clinical oncology (01.02.2014)
Published in Journal of clinical oncology (01.02.2014)
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Genetic and Functional Investigation of Germline JAK2 Alleles That Predispose to Myeloproliferative Neoplasms
Schram, Alison M, Xu, Xing, Kilpivaara, Outi, Mukherjee, Semanti, Viny, Aaron D, Guryanova, Olga, Klein, Robert J, Levine, Ross L
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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Transcriptional regulation and prostate cancer risk loci
Klein, Robert J., Xu, Xing, Hussain, Wasay, Farber, James, Vaananen, Riina-Minna, Taimen, Pekka, Vijai, Joseph, Hayes, James E., Lilja, Hans, Pettersson, Kim, Rubin, Mark A., Demichelis, Francesca, Offit, Kenneth
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
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Polymorphisms at the Microseminoprotein-beta (MSMB) Locus Associated With Physiological Variation in Beta-Microseminoprotein (β-MSP) and Prostate Specific Antigen (PSA) Levels
Xu, Xing, Valtonen-André, Camilla, Sävblom, Charlotta, Halldén, Christer, Lilja, Hans, Klein, Robert J.
Published in Cancer epidemiology, biomarkers & prevention (01.08.2010)
Published in Cancer epidemiology, biomarkers & prevention (01.08.2010)
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Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis
van Rooij, Frank J.A., Qayyum, Rehan, Smith, Albert V., Zhou, Yi, Trompet, Stella, Tanaka, Toshiko, Keller, Margaux F., Chang, Li-Ching, Schmidt, Helena, Yang, Min-Lee, Chen, Ming-Huei, Hayes, James, Johnson, Andrew D., Yanek, Lisa R., Mueller, Christian, Lange, Leslie, Floyd, James S., Ghanbari, Mohsen, Zonderman, Alan B., Jukema, J. Wouter, Hofman, Albert, van Duijn, Cornelia M., Desch, Karl C., Saba, Yasaman, Ozel, Ayse B., Snively, Beverly M., Wu, Jer-Yuarn, Schmidt, Reinhold, Fornage, Myriam, Klein, Robert J., Fox, Caroline S., Matsuda, Koichi, Kamatani, Naoyuki, Wild, Philipp S., Stott, David J., Ford, Ian, Slagboom, P. Eline, Yang, Jaden, Chu, Audrey Y., Lambert, Amy J., Uitterlinden, André G., Franco, Oscar H., Hofer, Edith, Ginsburg, David, Hu, Bella, Keating, Brendan, Schick, Ursula M., Brody, Jennifer A., Li, Jun Z., Chen, Zhao, Zeller, Tanja, Guralnik, Jack M., Chasman, Daniel I., Peters, Luanne L., Kubo, Michiaki, Becker, Diane M., Li, Jin, Eiriksdottir, Gudny, Rotter, Jerome I., Levy, Daniel, Grossmann, Vera, Patel, Kushang V., Chen, Chien-Hsiun, Ridker, Paul M., Tang, Hua, Launer, Lenore J., Rice, Kenneth M., Li-Gao, Ruifang, Ferrucci, Luigi, Evans, Michelle K., Choudhuri, Avik, Trompouki, Eirini, Abraham, Brian J., Yang, Song, Takahashi, Atsushi, Kamatani, Yoichiro, Kooperberg, Charles, Harris, Tamara B., Jee, Sun Ha, Coresh, Josef, Tsai, Fuu-Jen, Longo, Dan L., Chen, Yuan-Tsong, Felix, Janine F., Yang, Qiong, Psaty, Bruce M., Boerwinkle, Eric, Becker, Lewis C., Mook-Kanamori, Dennis O., Wilson, James G., Gudnason, Vilmundur, O'Donnell, Christopher J., Dehghan, Abbas, Cupples, L. Adrienne, Nalls, Michael A., Morris, Andrew P., Okada, Yukinori, Reiner, Alexander P., Zon, Leonard I., Ganesh, Santhi K.
Published in American journal of human genetics (05.01.2017)
Published in American journal of human genetics (05.01.2017)
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Tissue-Specific Enrichment of Lymphoma Risk Loci in Regulatory Elements: e0139360
Hayes, James E, Trynka, Gosia, Vijai, Joseph, Offit, Kenneth, Raychaudhuri, Soumya, Klein, Robert J
Published in PloS one (01.09.2015)
Published in PloS one (01.09.2015)
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Genome sequencing of multiple primary tumors to reveal underlying germline cancer susceptibility
Schrader, Kasmintan A., Stratton, Kelly Lynn, Murali, Rajmohan, Laitman, Yael, Cavallone, Luca, Offit, Lily, Wen, Yong Hannah, Shah, Sohela, Rau-Murthy, Rohini, Manschreck, Christopher, Otegbeye, Ebunoluwa, Corines, Marina, Kauff, Noah D., Klein, Robert J., Robson, Mark E., Stadler, Zsofia Kinga, Friedman, Eitan, Foulkes, William, Vijai, Joseph, Offit, Kenneth
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
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G enetic variants associated with longer telomere length are associated with increased lung cancer risk among never‐smoking women in Asia: a report from the female lung cancer consortium in Asia
Machiela, Mitchell J., Hsiung, Chao Agnes, Shu, Xiao‐Ou, Seow, Wei Jie, Wang, Zhaoming, Matsuo, Keitaro, Hong, Yun‐Chul, Seow, Adeline, Wu, Chen, Hosgood, H. Dean, Chen, Kexin, Wang, Jiu‐Cun, Wen, Wanqing, Cawthon, Richard, Chatterjee, Nilanjan, Hu, Wei, Caporaso, Neil E., Park, Jae Yong, Chen, Chien‐Jen, Kim, Yeul Hong, Kim, Young Tae, Landi, Maria Teresa, Shen, Hongbing, Lawrence, Charles, Burdett, Laurie, Yeager, Meredith, Chang, I‐Shou, Mitsudomi, Tetsuya, Kim, Hee Nam, Chang, Gee‐Chen, Bassig, Bryan A., Tucker, Margaret, Wei, Fusheng, Yin, Zhihua, An, She‐Juan, Qian, Biyun, Lee, Victor Ho Fun, Lu, Daru, Liu, Jianjun, Jeon, Hyo‐Sung, Hsiao, Chin‐Fu, Sung, Jae Sook, Kim, Jin Hee, Gao, Yu‐Tang, Tsai, Ying‐Huang, Jung, Yoo Jin, Guo, Huan, Hu, Zhibin, Hutchinson, Amy, Wang, Wen‐Chang, Klein, Robert J., Chung, Charles C., Oh, In‐Jae, Chen, Kuan‐Yu, Berndt, Sonja I., Wu, Wei, Chang, Jiang, Zhang, Xu‐Chao, Huang, Ming‐Shyan, Zheng, Hong, Wang, Junwen, Zhao, Xueying, Li, Yuqing, Choi, Jin Eun, Su, Wu‐Chou, Park, Kyong Hwa, Sung, Sook Whan, Chen, Yuh‐Min, Liu, Li, Kang, Chang Hyun, Hu, Lingmin, Chen, Chung‐Hsing, Pao, William, Kim, Young‐Chul, Yang, Tsung‐Ying, Xu, Jun, Guan, Peng, Tan, Wen, Su, Jian, Wang, Chih‐Liang, Li, Haixin, Sihoe, Alan Dart Loon, Zhao, Zhenhong, Chen, Ying, Choi, Yi Young, Hung, Jen‐Yu, Kim, Jun Suk, Yoon, Ho‐Il, Cai, Qiuyin, Lin, Chien‐Chung, Park, In Kyu, Xu, Ping, Dong, Jing, Kim, Christopher, He, Qincheng, Perng, Reury‐Perng, Kohno, Takashi, Kweon, Sun‐Seog, Chen, Chih‐Yi, Vermeulen, Roel C.H
Published in International journal of cancer (15.07.2015)
Published in International journal of cancer (15.07.2015)
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A common prostate cancer risk variant 5’ of MSMB (microseminoprotein-beta) is a strong predictor of circulating MSP (microseminoprotein) in multiple populations
Waters, Kevin M., Stram, Daniel O., Le Marchand, Loic, Klein, Robert J., Valtonen-André, Camilla, Peltola, Mari, Kolonel, Laurence N., Henderson, Brian E., Lilja, Hans, Haiman, Christopher A.
Published in Cancer epidemiology, biomarkers & prevention (24.08.2010)
Published in Cancer epidemiology, biomarkers & prevention (24.08.2010)
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Identification of a recurrent germline PAX5 mutation and susceptibility to pre-B cell acute lymphoblastic leukemia
Shah, Sohela, Schrader, Kasmintan A., Waanders, Esmé, Timms, Andrew E., Vijai, Joseph, Miething, Cornelius, Wechsler, Jeremy, Yang, Jun, Hayes, James, Klein, Robert J., Zhang, Jinghui, Wei, Lei, Wu, Gang, Rusch, Michael, Nagahawatte, Panduka, Ma, Jing, Chen, Shann-Ching, Song, Guangchun, Cheng, Jinjun, Meyers, Paul, Bhojwani, Deepa, Jhanwar, Suresh, Maslak, Peter, Fleisher, Martin, Littman, Jason, Offit, Lily, Rau-Murthy, Rohini, Fleischut, Megan Harlan, Corines, Marina, Murali, Rajmohan, Gao, Xiaoni, Manschreck, Christopher, Kitzing, Thomas, Murty, Vundavalli V., Raimondi, Susana, Kuiper, Roland P., Simons, Annet, Schiffman, Joshua D., Onel, Kenan, Plon, Sharon E., Wheeler, David, Ritter, Deborah, Ziegler, David S., Tucker, Kathy, Sutton, Rosemary, Chenevix-Trench, Georgia, Li, Jun, Huntsman, David G., Hansford, Samantha, Senz, Janine, Walsh, Thomas, Lee, Ming, Hahn, Christopher N., Roberts, Kathryn, King, Mary-Claire, Lo, Sarah M., Levine, Ross L., Viale, Agnes, Socci, Nicholas D., Nathanson, Katherine L., Scott, Hamish S., Daly, Mark, Lipkin, Steven M., Lowe, Scott W., Downing, James R., Altshuler, David, Sandlund, John T., Horwitz, Marshall S., Mullighan, Charles G., Offit, Kenneth
Published in Nature genetics (08.09.2013)
Published in Nature genetics (08.09.2013)
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Haplotype structure in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers
Im, Kate M., Kirchhoff, Tomas, Wang, Xianshu, Green, Todd, Chow, Clement Y., Korn, Joshua, Gaudet, Mia M., Fredericksen, Zachary, Shane Pankratz, V., Guiducci, Candace, Crenshaw, Andrew, McGuffog, Lesley, Kartsonaki, Christiana, Morrison, Jonathan, Healey, Sue, Sinilnikova, Olga M., Mai, Phuong L., Greene, Mark H., Piedmonte, Marion, Rubinstein, Wendy S., Hogervorst, Frans B., Rookus, Matti A., Collée, J. Margriet, Hoogerbrugge, Nicoline, Meijers-Heijboer, Hanne E. J., Van Roozendaal, Cees E., Perez-Segura, Pedro, Jakubowska, Anna, Huzarski, Tomasz, Blecharz, Paweł, Nevanlinna, Heli, Aittomäki, Kristiina, Lazaro, Conxi, Blanco, Ignacio, Barkardottir, Rosa B., D’Andrea, Emma, Devilee, Peter, Olopade, Olufunmilayo I., Peissel, Bernard, Bonanni, Bernardo, Peterlongo, Paolo, Singer, Christian F., Rennert, Gad, Lejbkowicz, Flavio, Andrulis, Irene L., Ozcelik, Hilmi, Toland, Amanda Ewart, Caligo, Maria Adelaide, Beattie, Mary S., Chan, Salina, Domchek, Susan M., Nathanson, Katherine L., Rebbeck, Timothy R., Phelan, Catherine, Narod, Steven, John, Esther M., Hopper, John L., Buys, Saundra S., Southey, Melissa C., Terry, Mary-Beth, Tung, Nadine, Hansen, Thomas v. O., Benitez, Javier, Weitzel, Jeffrey N., Garber, Judy, Hamann, Ute, Peock, Susan, Cook, Margaret, Oliver, Clare T., Frost, Debra, Eeles, Ros, Izatt, Louise, Paterson, Joan, Brewer, Carole, Hodgson, Shirley, Porteous, Mary, Walker, Lisa, Rogers, Mark T., Side, Lucy E., Godwin, Andrew K., Wappenschmidt, Barbara, Laitman, Yael, Deissler, Helmut, Varon-Mateeva, Raymonda, Preisler-Adams, Sabine, Kast, Karin, Venat-Bouvet, Laurence, Stoppa-Lyonnet, Dominique, Chenevix-Trench, Georgia, Easton, Douglas F., Klein, Robert J., Daly, Mark J., Friedman, Eitan, Dean, Michael, Clark, Andrew G., Altshuler, David M., Antoniou, Antonis C., Couch, Fergus J., Offit, Kenneth, Gold, Bert
Published in Human genetics (01.11.2011)
Published in Human genetics (01.11.2011)
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