Identifying the Proteins to Which Small-Molecule Probes and Drugs Bind in Cells
Ong, Shao-En, Schenone, Monica, Margolin, Adam A., Li, Xiaoyu, Do, Kathy, Doud, Mary K., Mani, D. R., Kuai, Letian, Wang, Xiang, Wood, John L., Tolliday, Nicola J., Koehler, Angela N., Marcaurelle, Lisa A., Golub, Todd R., Gould, Robert J., Schreiber, Stuart L., Carr, Steven A.
Published in Proceedings of the National Academy of Sciences - PNAS (24.03.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (24.03.2009)
Get full text
Journal Article
Identification of Regulators of Polyploidization Presents Therapeutic Targets for Treatment of AMKL
Wen, Qiang, Goldenson, Benjamin, Silver, Serena J., Schenone, Monica, Dancik, Vlado, Huang, Zan, Wang, Ling-Zhi, Lewis, Timothy A., An, W. Frank, Li, Xiaoyu, Bray, Mark-Anthony, Thiollier, Clarisse, Diebold, Lauren, Gilles, Laure, Vokes, Martha S., Moore, Christopher B., Bliss-Moreau, Meghan, VerPlank, Lynn, Tolliday, Nicola J., Mishra, Rama, Vemula, Sasidhar, Shi, Jianjian, Wei, Lei, Kapur, Reuben, Lopez, Cécile K., Gerby, Bastien, Ballerini, Paola, Pflumio, Francoise, Gilliland, D. Gary, Goldberg, Liat, Birger, Yehudit, Izraeli, Shai, Gamis, Alan S., Smith, Franklin O., Woods, William G., Taub, Jeffrey, Scherer, Christina A., Bradner, James E., Goh, Boon-Cher, Mercher, Thomas, Carpenter, Anne E., Gould, Robert J., Clemons, Paul A., Carr, Steven A., Root, David E., Schreiber, Stuart L., Stern, Andrew M., Crispino, John D.
Published in Cell (03.08.2012)
Published in Cell (03.08.2012)
Get full text
Journal Article
Safety and efficacy of losmapimod in facioscapulohumeral muscular dystrophy (ReDUX4): a randomised, double-blind, placebo-controlled phase 2b trial
Tawil, Rabi, Wagner, Kathryn R, Hamel, Johanna I, Leung, Doris G, Statland, Jeffrey M, Wang, Leo H, Genge, Angela, Sacconi, Sabrina, Lochmüller, Hanns, Reyes-Leiva, David, Diaz-Manera, Jordi, Alonso-Perez, Jorge, Muelas, Nuria, Vilchez, Juan J, Pestronk, Alan, Gibson, Summer, Goyal, Namita A, Hayward, Lawrence J, Johnson, Nicholas, LoRusso, Samantha, Freimer, Miriam, Shieh, Perry B, Subramony, S H, van Engelen, Baziel, Kools, Joost, Leinhard, Olof Dahlqvist, Widholm, Per, Morabito, Christopher, Moxham, Christopher M, Cadavid, Diego, Mellion, Michelle L, Odueyungbo, Adefowope, Tracewell, William G, Accorsi, Anthony, Ronco, Lucienne, Gould, Robert J, Shoskes, Jennifer, Rojas, Luis Alejandro, Jiang, John G
Published in Lancet neurology (01.05.2024)
Published in Lancet neurology (01.05.2024)
Get full text
Journal Article
Climate Discussion Echoes Tobacco Debate
GOULD, ROBERT J., MAIBACH, EDWARD
Published in Science (American Association for the Advancement of Science) (18.04.2014)
Published in Science (American Association for the Advancement of Science) (18.04.2014)
Get full text
Journal Article
Clinical significance of serum autoantibodies in patients with NAFLD: results from the nonalcoholic steatohepatitis clinical research network
Vuppalanchi, Raj, Gould, Robert J., Wilson, Laura A., Unalp-Arida, Aynur, Cummings, Oscar W., Chalasani, Naga, Kowdley, Kris V.
Published in Hepatology international (01.01.2012)
Published in Hepatology international (01.01.2012)
Get full text
Journal Article
Generation and Characterization of a Human Bradykinin Receptor B1 Transgenic Rat as a Pharmacodynamic Model
Hess, J Fred, Ransom, Richard W, Zeng, Zhizhen, Chang, Raymond S L, Hey, Patricia J, Warren, Lee, Harrell, Charles M, Murphy, Kathryn L, Chen, Tsing-Bau, Miller, Patricia J, Lis, Edward, Reiss, Duane, Gibson, Raymond E, Markowitz, M Kristine, DiPardo, Robert M, Su, Dai-Shi, Bock, Mark G, Gould, Robert J, Pettibone, Douglas J
Published in The Journal of pharmacology and experimental therapeutics (01.08.2004)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2004)
Get full text
Journal Article
A Growth Hormone Secretagogue Prevents Ischemic-Induced Mortality Independently of the Growth Hormone Pathway in Dogs with Chronic Dilated Cardiomyopathy
Shen, You-Tang, Lynch, Joseph J, Hargreaves, Richard J, Gould, Robert J
Published in The Journal of pharmacology and experimental therapeutics (01.08.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2003)
Get full text
Journal Article
A 5-bp deletion in ELOVL4 is associated with two related forms of autosomal dominant macular dystrophy
Petrukhin, Konstantin, Zhang, Kang, Kniazeva, Marina, Han, Min, Li, Wen, Yu, Zhengya, Yang, Zhenglin, Li, Yang, Metzker, Michael L, Allikmets, Rando, Zack, Donald J, Kakuk, Laura E, Lagali, Pamela S, Wong, Paul W, MacDonald, Ian M, Sieving, Paul A, Figueroa, David J, Austin, Christopher P, Gould, Robert J, Ayyagari, Radha
Published in Nature genetics (01.01.2001)
Published in Nature genetics (01.01.2001)
Get full text
Journal Article
An antibody against the exosite of the cloned thrombin receptor inhibits experimental arterial thrombosis in the African green monkey
COOK, J. J, SITKO, G. R, BEDNAR, B, CONDRA, C, MELLOTT, M. J, DONG-MEI FENG, NUTT, R. F, SHAFER, J. A, GOULD, R. J, CONNOLLY, T. M
Published in Circulation (New York, N.Y.) (15.06.1995)
Published in Circulation (New York, N.Y.) (15.06.1995)
Get full text
Journal Article
Non-Peptide Glycoprotein IIb/IIIa Antagonists. 11. Design and in Vivo Evaluation of 3,4-Dihydro-1(1H)-isoquinolinone-Based Antagonists and Ethyl Ester Prodrugs
Hutchinson, John H, Cook, Jacquelynn J, Brashear, Karen M, Breslin, Michael J, Glass, Joan D, Gould, Robert J, Halczenko, Wasyl, Holahan, Marie A, Lynch, Robert J, Sitko, Gary R, Stranieri, Maria T, Hartman, George D
Published in Journal of medicinal chemistry (08.11.1996)
Published in Journal of medicinal chemistry (08.11.1996)
Get full text
Journal Article
Time to Take Action on Climate Communication
BOWMAN, THOMAS E., MAIBACH, EDWARD, MANN, MICHAEL E., SOMERVILLE, RICHARD C. J., SELTSER, BARRY J., FISCHHOFF, BARUCH, GARDINER, STEPHEN M., GOULD, ROBERT J., LEISEROWITZ, ANTHONY, YOHE, GARY
Published in Science (American Association for the Advancement of Science) (19.11.2010)
Published in Science (American Association for the Advancement of Science) (19.11.2010)
Get full text
Journal Article
Effects of the prototype serotonin 5-HT1B/1D receptor agonist sumatriptan and the calcitonin gene-related peptide (CGRP) receptor antagonist CGRP8-37 on myocardial reactive hyperemic response in conscious dogs
LYNCH, Joseph J, SHEN, You-Tang, PITTMAN, Tamara J, ANDERSON, Kenneth D, KOBLAN, Kenneth S, GOULD, Robert J, REGAN, Christopher P, KANE, Stefanie A
Published in European journal of pharmacology (25.11.2009)
Published in European journal of pharmacology (25.11.2009)
Get full text
Journal Article
Non-Peptide Fibrinogen Receptor Antagonists. 7. Design and Synthesis of a Potent, Orally Active Fibrinogen Receptor Antagonist
Duggan, Mark E, Naylor-Olsen, Adel M, Perkins, James J, Anderson, Paul S, Chang, Charles T.-C, Cook, Jacquelynn J, Gould, Robert J, Ihle, Nathan C, Hartman, George D
Published in Journal of medicinal chemistry (01.08.1995)
Published in Journal of medicinal chemistry (01.08.1995)
Get full text
Journal Article
Nonpeptide glycoprotein IIb/IIIa inhibitors: Substituted quinazolinediones and quinazolinones as potent fibrinogen receptor antagonists
Liverton, Nigel J., Armstrong, Donna J., Claremon, David A., Remy, David C., Baldvin, John J., Lynch, Robert J., Zhang, Guixiang, Gould, Robert J.
Published in Bioorganic & medicinal chemistry letters (03.03.1998)
Published in Bioorganic & medicinal chemistry letters (03.03.1998)
Get full text
Journal Article
Non-Peptide Fibrinogen Receptor Antagonists. 2. Optimization of a Tyrosine Template as a Mimic for Arg-Gly-Asp
Egbertson, Melissa S, Chang, Charles T.-C, Duggan, Mark E, Gould, Robert J, Halczenko, Wasyl, Hartman, George D, Laswell, William L, Lynch, Joseph J, Lynch, Robert J
Published in Journal of medicinal chemistry (01.08.1994)
Published in Journal of medicinal chemistry (01.08.1994)
Get full text
Journal Article
Pharmacokinetics and pharmacodynamics of MK-383, a selective non-peptide platelet glycoprotein-IIb/IIIa receptor antagonist, in healthy men
Barrett, J S, Murphy, G, Peerlinck, K, De Lepeleire, I, Gould, R J, Panebianco, D, Hand, E, Deckmyn, H, Vermylen, J, Arnout, J
Published in Clinical pharmacology and therapeutics (01.10.1994)
Published in Clinical pharmacology and therapeutics (01.10.1994)
Get more information
Journal Article
Discovery of a nonpeptidic small molecule antagonist of the human platelet thrombin receptor (PAR-1)
Nantermet, Philippe G, Barrow, James C, Lundell, George F, Pellicore, Janetta M, Rittle, Kenneth E, Young, MaryBeth, Freidinger, Roger M, Connolly, Thomas M, Condra, Cindra, Karczewski, Jerzy, Bednar, Rodney A, Gaul, Stanley L, Gould, Robert J, Prendergast, Kris, Selnick, Harold G
Published in Bioorganic & medicinal chemistry letters (11.02.2002)
Published in Bioorganic & medicinal chemistry letters (11.02.2002)
Get full text
Journal Article