ModraDoc006, an oral docetaxel formulation in combination with ritonavir (ModraDoc006/r), in metastatic castration‐resistant prostate cancer patients: A phase Ib study
Vermunt, Marit A. C., Robbrecht, Debbie G. J., Devriese, Lot A., Janssen, Julie M., Thijssen, Bas, Keessen, Marianne, Eijk, Maarten, Kessels, Rob, Eskens, Ferry A. L. M., Beijnen, Jos H., Mehra, Niven, Bergman, Andries M.
Published in Cancer reports (01.08.2021)
Published in Cancer reports (01.08.2021)
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A first-in-human phase 1 and pharmacological study of TAS-119, a novel selective Aurora A kinase inhibitor in patients with advanced solid tumours
Robbrecht, Debbie G J, Lopez, Juanita, Calvo, Emiliano, He, Xiaomin, Hiroshi, Hirai, Soni, Nital, Cook, Natalie, Dowlati, Afshin, Fasolo, Angelica, Moreno, Victor, Eskens, Ferry A L M, de Bono, Johann S
Published in British journal of cancer (19.01.2021)
Published in British journal of cancer (19.01.2021)
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A blood-based immune marker for resistance to pembrolizumab in patients with metastatic urothelial cancer
Rijnders, Maud, Robbrecht, Debbie G. J., Oostvogels, Astrid A. M., van Brakel, Mandy, Boormans, Joost L., Aarts, Maureen J. B., Balcioglu, Hayri E., Hamberg, Paul, Voortman, Jens, Westgeest, Hans M., Lolkema, Martijn P., de Wit, Ronald, van der Veldt, Astrid A. M., Debets, Reno
Published in Cancer Immunology, Immunotherapy (01.03.2023)
Published in Cancer Immunology, Immunotherapy (01.03.2023)
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Gene-expression-based T-Cell-to-Stroma Enrichment (TSE) score predicts response to immune checkpoint inhibitors in urothelial cancer
Rijnders, Maud, Nakauma-González, J Alberto, Robbrecht, Debbie G J, Gil-Jimenez, Alberto, Balcioglu, Hayri E, Oostvogels, Astrid A M, Aarts, Maureen J B, Boormans, Joost L, Hamberg, Paul, van der Heijden, Michiel S, Szabados, Bernadett E, van Leenders, Geert J L H, Mehra, Niven, Voortman, Jens, Westgeest, Hans M, de Wit, Ronald, van der Veldt, Astrid A M, Debets, Reno, Lolkema, Martijn P
Published in Nature communications (14.02.2024)
Published in Nature communications (14.02.2024)
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Genome‐wide aneuploidy detected by mFast‐SeqS in circulating cell‐free DNA is associated with poor response to pembrolizumab in patients with advanced urothelial cancer
Mendelaar, Pauline A. J., Robbrecht, Debbie G. J., Rijnders, Maud, Wit, Ronald, Weerd, Vanja, Deger, Teoman, Westgeest, Hans M., Aarts, Maureen J. B., Voortman, Jens, Martens, John W. M., Veldt, Astrid A. M., Nakauma‐González, José Alberto, Wilting, Saskia M., Lolkema, Martijn
Published in Molecular oncology (01.05.2022)
Published in Molecular oncology (01.05.2022)
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Patients with Biallelic BRCA1/2 Inactivation Respond to Olaparib Treatment Across Histologic Tumor Types
van der Wijngaart, Hanneke, Hoes, Louisa R, van Berge Henegouwen, J Maxime, van der Velden, Daphne L, Zeverijn, Laurien J, Roepman, Paul, van Werkhoven, Erik, de Leng, Wendy W J, Jansen, Anne M L, Mehra, Niven, Robbrecht, Debbie G J, Labots, Mariette, de Groot, Derk Jan A, Hoeben, Ann, Hamberg, Paul, Gelderblom, Hans, Voest, Emile E, Verheul, Henk M W
Published in Clinical cancer research (15.11.2021)
Published in Clinical cancer research (15.11.2021)
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Quantification and clinical validation of the selective MET kinase inhibitor DO-2 and its metabolites DO-5 and M3 in human plasma
Sikkema, Barend J., Mathijssen, Ron H.J., Robbrecht, Debbie G.J., Perera, Timothy P.S., Koolen, Stijn L.W., de Bruijn, Peter
Published in Journal of pharmaceutical and biomedical analysis (15.03.2024)
Published in Journal of pharmaceutical and biomedical analysis (15.03.2024)
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Anti-PD-1 Efficacy in Patients with Metastatic Urothelial Cancer Associates with Intratumoral Juxtaposition of T Helper-Type 1 and CD8 + T cells
Rijnders, Maud, Balcioglu, Hayri E, Robbrecht, Debbie G J, Oostvogels, Astrid A M, Wijers, Rebecca, Aarts, Maureen J B, Hamberg, Paul, van Leenders, Geert J L H, Nakauma-González, J Alberto, Voortman, Jens, Westgeest, Hans M, Boormans, Joost L, de Wit, Ronald, Lolkema, Martijn P, van der Veldt, Astrid A M, Debets, Reno
Published in Clinical cancer research (01.01.2022)
Published in Clinical cancer research (01.01.2022)
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Are primary tumors suitable for biomarker-guided treatment of metastatic urothelial cancer?
Scholtes, Mathijs P., van Leenders, Geert J. L. H., Robbrecht, Debbie G. J., Boormans, Joost L., Zuiverloon, Tahlita C. M.
Published in Translational andrology and urology (31.08.2024)
Published in Translational andrology and urology (31.08.2024)
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Molecularly guided therapy versus chemotherapy after disease control in unfavourable cancer of unknown primary (CUPISCO): an open-label, randomised, phase 2 study
Krämer, Alwin, Bochtler, Tilmann, Pauli, Chantal, Shiu, Kai-Keen, Cook, Natalie, de Menezes, Juliana Janoski, Pazo-Cid, Roberto A, Losa, Ferran, Robbrecht, Debbie GJ, Tomášek, Jiří, Arslan, Cagatay, Özgüroğlu, Mustafa, Stahl, Michael, Bigot, Frédéric, Kim, Sun Young, Naito, Yoichi, Italiano, Antoine, Chalabi, Nasséra, Durán-Pacheco, Gonzalo, Michaud, Chantal, Scarato, Jeremy, Thomas, Marlene, Ross, Jeffrey S, Moch, Holger, Mileshkin, Linda
Published in The Lancet (British edition) (10.08.2024)
Published in The Lancet (British edition) (10.08.2024)
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Treatment Patterns and Use of Immune Checkpoint Inhibitors Among Patients with Metastatic Bladder Cancer in a Dutch Nationwide Cohort
Richters, Anke, Robbrecht, Debbie G J, Meijer, Richard P, van der Heijden, Antoine G, Kiemeney, Lambertus A L M, van den Bosch, Joan, Suelmann, Britt B M, Özdemir, Berna C, Mehra, Niven, Aben, Katja K H
Published in European urology open science (Online) (01.01.2024)
Published in European urology open science (Online) (01.01.2024)
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