The Clinical Potential of Senolytic Drugs
Kirkland, James L., Tchkonia, Tamara, Zhu, Yi, Niedernhofer, Laura J., Robbins, Paul D.
Published in Journal of the American Geriatrics Society (JAGS) (01.10.2017)
Published in Journal of the American Geriatrics Society (JAGS) (01.10.2017)
Get full text
Journal Article
Regulation of chronic inflammatory and immune processes by extracellular vesicles
Robbins, Paul D, Dorronsoro, Akaitz, Booker, Cori N
Published in The Journal of clinical investigation (01.04.2016)
Published in The Journal of clinical investigation (01.04.2016)
Get full text
Journal Article
Cellular senescence: a key therapeutic target in aging and diseases
Zhang, Lei, Pitcher, Louise E, Yousefzadeh, Matthew J, Niedernhofer, Laura J, Robbins, Paul D, Zhu, Yi
Published in The Journal of clinical investigation (01.08.2022)
Published in The Journal of clinical investigation (01.08.2022)
Get full text
Journal Article
Gene Delivery to Joints by Intra-Articular Injection
Evans, Christopher H, Ghivizzani, Steven C, Robbins, Paul D
Published in Human gene therapy (01.01.2018)
Published in Human gene therapy (01.01.2018)
Get more information
Journal Article
Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span
Robbins, Paul D, Jurk, Diana, Khosla, Sundeep, Kirkland, James L, LeBrasseur, Nathan K, Miller, Jordan D, Passos, João F, Pignolo, Robert J, Tchkonia, Tamar, Niedernhofer, Laura J
Published in Annual review of pharmacology and toxicology (06.01.2021)
Published in Annual review of pharmacology and toxicology (06.01.2021)
Get full text
Journal Article
Nuclear Genomic Instability and Aging
Niedernhofer, Laura J, Gurkar, Aditi U, Wang, Yinsheng, Vijg, Jan, Hoeijmakers, Jan H.J, Robbins, Paul D
Published in Annual review of biochemistry (20.06.2018)
Published in Annual review of biochemistry (20.06.2018)
Get full text
Journal Article
A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues
Saul, Dominik, Kosinsky, Robyn Laura, Atkinson, Elizabeth J., Doolittle, Madison L., Zhang, Xu, LeBrasseur, Nathan K., Pignolo, Robert J., Robbins, Paul D., Niedernhofer, Laura J., Ikeno, Yuji, Jurk, Diana, Passos, João F., Hickson, LaTonya J., Xue, Ailing, Monroe, David G., Tchkonia, Tamara, Kirkland, James L., Farr, Joshua N., Khosla, Sundeep
Published in Nature communications (16.08.2022)
Published in Nature communications (16.08.2022)
Get full text
Journal Article
Identification of HSP90 inhibitors as a novel class of senolytics
Fuhrmann-Stroissnigg, Heike, Ling, Yuan Yuan, Zhao, Jing, McGowan, Sara J., Zhu, Yi, Brooks, Robert W., Grassi, Diego, Gregg, Siobhan Q., Stripay, Jennifer L., Dorronsoro, Akaitz, Corbo, Lana, Tang, Priscilla, Bukata, Christina, Ring, Nadja, Giacca, Mauro, Li, Xuesen, Tchkonia, Tamara, Kirkland, James L., Niedernhofer, Laura J., Robbins, Paul D.
Published in Nature communications (04.09.2017)
Published in Nature communications (04.09.2017)
Get full text
Journal Article
Cellular senescence mediates fibrotic pulmonary disease
Schafer, Marissa J., White, Thomas A., Iijima, Koji, Haak, Andrew J., Ligresti, Giovanni, Atkinson, Elizabeth J., Oberg, Ann L., Birch, Jodie, Salmonowicz, Hanna, Zhu, Yi, Mazula, Daniel L., Brooks, Robert W., Fuhrmann-Stroissnigg, Heike, Pirtskhalava, Tamar, Prakash, Y. S., Tchkonia, Tamara, Robbins, Paul D., Aubry, Marie Christine, Passos, João F., Kirkland, James L., Tschumperlin, Daniel J., Kita, Hirohito, LeBrasseur, Nathan K.
Published in Nature communications (23.02.2017)
Published in Nature communications (23.02.2017)
Get full text
Journal Article
Role of Cellular Senescence in Type II Diabetes
Narasimhan, Akilavalli, Flores, Rafael R, Robbins, Paul D, Niedernhofer, Laura J
Published in Endocrinology (Philadelphia) (01.10.2021)
Published in Endocrinology (Philadelphia) (01.10.2021)
Get full text
Journal Article
Cell-type specific penetrating peptides: therapeutic promises and challenges
Get full text
Journal Article
Book Review
Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors
Zhu, Yi, Tchkonia, Tamara, Fuhrmann‐Stroissnigg, Heike, Dai, Haiming M., Ling, Yuanyuan Y., Stout, Michael B., Pirtskhalava, Tamar, Giorgadze, Nino, Johnson, Kurt O., Giles, Cory B., Wren, Jonathan D., Niedernhofer, Laura J., Robbins, Paul D., Kirkland, James L.
Published in Aging cell (01.06.2016)
Published in Aging cell (01.06.2016)
Get full text
Journal Article
Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice
Yousefzadeh, Matthew J., Zhao, Jing, Bukata, Christina, Wade, Erin A., McGowan, Sara J., Angelini, Luise A., Bank, Michael P., Gurkar, Aditi U., McGuckian, Collin A., Calubag, Mariah F., Kato, Jonathan I., Burd, Christin E., Robbins, Paul D., Niedernhofer, Laura J.
Published in Aging cell (01.03.2020)
Published in Aging cell (01.03.2020)
Get full text
Journal Article
Plasma-derived exosome characterization reveals a distinct microRNA signature in long duration Type 1 diabetes
Garcia-Contreras, Marta, Shah, Sanket H., Tamayo, Alejandro, Robbins, Paul D., Golberg, Ronald B., Mendez, Armando J., Ricordi, Camillo
Published in Scientific reports (20.07.2017)
Published in Scientific reports (20.07.2017)
Get full text
Journal Article
Immune Senescence, Immunosenescence and Aging
Lee, Kyoo-A, Flores, Rafael R, Jang, In Hwa, Saathoff, Ashley, Robbins, Paul D
Published in Frontiers in aging (30.05.2022)
Published in Frontiers in aging (30.05.2022)
Get full text
Journal Article
Local senolysis in aged mice only partially replicates the benefits of systemic senolysis
Farr, Joshua N, Saul, Dominik, Doolittle, Madison L, Kaur, Japneet, Rowsey, Jennifer L, Vos, Stephanie J, Froemming, Mitchell N, Lagnado, Anthony B, Zhu, Yi, Weivoda, Megan, Ikeno, Yuji, Pignolo, Robert J, Niedernhofer, Laura J, Robbins, Paul D, Jurk, Diana, Passos, João F, LeBrasseur, Nathan K, Tchkonia, Tamara, Kirkland, James L, Monroe, David G, Khosla, Sundeep
Published in The Journal of clinical investigation (17.04.2023)
Published in The Journal of clinical investigation (17.04.2023)
Get full text
Journal Article
Cytoskeleton stiffness regulates cellular senescence and innate immune response in Hutchinson–Gilford Progeria Syndrome
Mu, Xiaodong, Tseng, Chieh, Hambright, William S., Matre, Polina, Lin, Chih‐Yi, Chanda, Palas, Chen, Wanqun, Gu, Jianhua, Ravuri, Sudheer, Cui, Yan, Zhong, Ling, Cooke, John P., Niedernhofer, Laura J., Robbins, Paul D., Huard, Johnny
Published in Aging cell (01.08.2020)
Published in Aging cell (01.08.2020)
Get full text
Journal Article