Regulation of human telomerase in homeostasis and disease
Roake, Caitlin M., Artandi, Steven E.
Published in Nature reviews. Molecular cell biology (01.07.2020)
Published in Nature reviews. Molecular cell biology (01.07.2020)
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Journal Article
HiChIRP reveals RNA-associated chromosome conformation
Mumbach, Maxwell R., Granja, Jeffrey M., Flynn, Ryan A., Roake, Caitlin M., Satpathy, Ansuman T., Rubin, Adam J., Qi, Yanyan, Jiang, Zhaozhao, Shams, Shadi, Louie, Bryan H., Guo, Jimmy K., Gennert, David G., Corces, M. Ryan, Khavari, Paul A., Atianand, Maninjay K., Artandi, Steven E., Fitzgerald, Katherine A., Greenleaf, William J., Chang, Howard Y.
Published in Nature methods (01.06.2019)
Published in Nature methods (01.06.2019)
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Journal Article
Control of Cellular Aging, Tissue Function, and Cancer by p53 Downstream of Telomeres
Roake, Caitlin M, Artandi, Steven E
Published in Cold Spring Harbor perspectives in medicine (01.05.2017)
Published in Cold Spring Harbor perspectives in medicine (01.05.2017)
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Journal Article
Acinar cell clonal expansion in pancreas homeostasis and carcinogenesis
Neuhöfer, Patrick, Roake, Caitlin M., Kim, Stewart J., Lu, Ryan J., West, Robert B., Charville, Gregory W., Artandi, Steven E.
Published in Nature (London) (30.09.2021)
Published in Nature (London) (30.09.2021)
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Journal Article
Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease
Roake, Caitlin M., Chen, Lu, Chakravarthy, Ananya L., Ferrell, James E., Raffa, Grazia D., Artandi, Steven E.
Published in Molecular cell (16.05.2019)
Published in Molecular cell (16.05.2019)
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Journal Article
An Activity Switch in Human Telomerase Based on RNA Conformation and Shaped by TCAB1
Chen, Lu, Roake, Caitlin M., Freund, Adam, Batista, Pedro J., Tian, Siqi, Yin, Yi A., Gajera, Chandresh R., Lin, Shengda, Lee, Byron, Pech, Matthew F., Venteicher, Andrew S., Das, Rhiju, Chang, Howard Y., Artandi, Steven E.
Published in Cell (28.06.2018)
Published in Cell (28.06.2018)
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Journal Article
Loss of Human TGS1 Hypermethylase Promotes Increased Telomerase RNA and Telomere Elongation
Chen, Lu, Roake, Caitlin M., Galati, Alessandra, Bavasso, Francesca, Micheli, Emanuela, Saggio, Isabella, Schoeftner, Stefan, Cacchione, Stefano, Gatti, Maurizio, Artandi, Steven E., Raffa, Grazia D.
Published in Cell reports (Cambridge) (04.02.2020)
Published in Cell reports (Cambridge) (04.02.2020)
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Journal Article
The S‐adenosylmethionine analog sinefungin inhibits the trimethylguanosine synthase TGS1 to promote telomerase activity and telomere lengthening
Galati, Alessandra, Scatolini, Livia, Micheli, Emanuela, Bavasso, Francesca, Cicconi, Alessandro, Maccallini, Paolo, Chen, Lu, Roake, Caitlin M., Schoeftner, Stefan, Artandi, Steven E., Gatti, Maurizio, Cacchione, Stefano, Raffa, Grazia D.
Published in FEBS letters (01.01.2022)
Published in FEBS letters (01.01.2022)
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Journal Article
Characterization of the cell of origin for small cell lung cancer
Park, Kwon-Sik, Liang, Mei-Chih, Raiser, David M., Zamponi, Raffaella, Roach, Rebecca R., Curtis, Stephen J., Walton, Zandra, Schaffer, Bethany E., Roake, Caitlin M., Zmoos, Anne-Flore, Kriegel, Christina, Wong, Kwok-Kin, Sage, Julien, Kim, Carla F.
Published in Cell cycle (Georgetown, Tex.) (15.08.2011)
Published in Cell cycle (Georgetown, Tex.) (15.08.2011)
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Journal Article
TGS1 impacts snRNA 3'-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration
Chen, Lu, Roake, Caitlin M, Maccallini, Paolo, Bavasso, Francesca, Dehghannasiri, Roozbeh, Santonicola, Pamela, Mendoza-Ferreira, Natalia, Scatolini, Livia, Rizzuti, Ludovico, Esposito, Alessandro, Gallotta, Ivan, Francia, Sofia, Cacchione, Stefano, Galati, Alessandra, Palumbo, Valeria, Kobin, Marie A, Tartaglia, Gian Gaetano, Colantoni, Alessio, Proietti, Gabriele, Wu, Yunming, Hammerschmidt, Matthias, De Pittà, Cristiano, Sales, Gabriele, Salzman, Julia, Pellizzoni, Livio, Wirth, Brunhilde, Di Schiavi, Elia, Gatti, Maurizio, Artandi, Steven E, Raffa, Grazia D
Published in Nucleic acids research (28.11.2022)
Published in Nucleic acids research (28.11.2022)
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Journal Article
Tissue-specific telomere shortening and degenerative changes in a patient with TINF2 mutation and dyskeratosis congenita
Roake, Caitlin M., Juntilla, Marisa, Agarwal-Hashmi, Rajni, Artandi, Steven, Kuo, Christin S.
Published in Human pathology : case reports (01.09.2021)
Published in Human pathology : case reports (01.09.2021)
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Journal Article
Mutant nucleophosmin1 (NPM1) Links Protein Translation with Oncogenic Metabolism in Leukemia
Juntilla, Marisa, Garbuzov, Alina, Ortiz, Natalie, Eberhard, Julia, Roake, Caitlin, Yin, Yi, Gruber, Josh, Artandi, Steven
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Functional Consequences of TCAB1 Mutations in Dyskeratosis Congenita
Sahoo, Sushree Sangita, Roake, Caitlin, Rindle, Liliana, Rössig, Claudia, Schmugge, Markus, Pastor, Victor B, Strahm, Brigitte, Niewisch, Marena R, Ruzaike, Gunda, Artandi, Steven, Niemeyer, Charlotte M, Börries, Melanie, Busch, Hauke, Wlodarski, Marcin
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
TGS1 controls snRNA 3’ end processing, prevents neurodegeneration and ameliorates SMN-dependent neurological phenotypes in vivo
Chen, Lu, Roake, Caitlin M, Maccallini, Paolo, Bavasso, Francesca, Dehghannasiri, Roozbeh, Santonicola, Pamela, Mendoza-Ferreira, Natalia, Scatolini, Livia, Rizzuti, Ludovico, Esposito, Alessandro, Gallotta, Ivan, Francia, Sofia, Cacchione, Stefano, Hammerschmidt, Matthias, De Pittà, Cristiano, Sales, Gabriele, Salzman, Julia, Pellizzoni, Livio, Wirth, Brunhilde, Elia Di Schiavi, Gatti, Maurizio, Artandi, Steven E, Raffa, Grazia D
Published in bioRxiv (27.10.2020)
Published in bioRxiv (27.10.2020)
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