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PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 3: Comparative assessement of prediction methods of human clearance

PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 3: Comparative assessement of prediction methods of human clearance

by Ring, Barbara J., Chien, Jenny Y., Adkison, Kimberly K., Jones, Hannah M., Rowland, Malcolm, Jones, Rhys Do, Yates, James W.T., Ku, M. Sherry, Gibson, Christopher R., He, Handan, Vuppugalla, Ragini, Marathe, Punit, Fischer, Volker, Dutta, Sandeep, Sinha, Vikash K., Björnsson, Thorir, Lavé, Thierry, Poulin, Patrick
Published in Journal of pharmaceutical sciences (01.10.2011)

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Low-Turnover Drug Molecules: A Current Challenge for Drug Metabolism Scientists

Low-Turnover Drug Molecules: A Current Challenge for Drug Metabolism Scientists

by Hutzler, J Matthew, Ring, Barbara J, Anderson, Shelby R
Published in Drug metabolism and disposition (01.12.2015)

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PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: Prediction of plasma concentration–time profiles in human by using the physiologically‐based pharmacokinetic modeling approach

PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: Prediction of plasma concentration–time profiles in human by using the physiologically‐based pharmacokinetic modeling approach

by Poulin, Patrick, Jones, Rhys D.O., Jones, Hannah M., Gibson, Christopher R., Rowland, Malcolm, Chien, Jenny Y., Ring, Barbara J., Adkison, Kimberly K., Ku, M. Sherry, He, Handan, Vuppugalla, Ragini, Marathe, Punit, Fischer, Volker, Dutta, Sandeep, Sinha, Vikash K., Björnsson, Thorir, Lavé, Thierry, Yates, James W.T.
Published in Journal of pharmaceutical sciences (01.10.2011)

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INTERACTIONS OF TWO MAJOR METABOLITES OF PRASUGREL, A THIENOPYRIDINE ANTIPLATELET AGENT, WITH THE CYTOCHROMES P450

INTERACTIONS OF TWO MAJOR METABOLITES OF PRASUGREL, A THIENOPYRIDINE ANTIPLATELET AGENT, WITH THE CYTOCHROMES P450

by FAYER REHMEL, Jessica L, ECKSTEIN, James A, FARID, Nagy A, HEIM, John B, KASPER, Steve C, KURIHARA, Atsushi, WRIGHTON, Steven A, RING, Barbara J
Published in Drug metabolism and disposition (01.04.2006)

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PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 2: Comparative assessment of prediction methods of human volume of distribution

PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 2: Comparative assessment of prediction methods of human volume of distribution

by Jones, Rhys Do, Jones, Hannah M., Rowland, Malcolm, Gibson, Christopher R., Yates, James W.T., Chien, Jenny Y., Ring, Barbara J., Adkison, Kimberly K., Ku, M. Sherry, He, Handan, Vuppugalla, Ragini, Marathe, Punit, Fischer, Volker, Dutta, Sandeep, Sinha, Vikash K., Björnsson, Thorir, Lavé, Thierry, Poulin, Patrick
Published in Journal of pharmaceutical sciences (01.10.2011)

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Comparative Metabolic Capabilities of CYP3A4, CYP3A5, and CYP3A7

Comparative Metabolic Capabilities of CYP3A4, CYP3A5, and CYP3A7

by WILLIAMS, J. Andrew, RING, Barbara J, CANTRELL, Varon E, JONES, David R, ECKSTEIN, James, RUTERBORIES, Kenneth, HAMMAN, Mitchell A, HALL, Stephen D, WRIGHTON, Steven A
Published in Drug metabolism and disposition (01.08.2002)

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Clinical pharmacokinetics of atomoxetine

Clinical pharmacokinetics of atomoxetine

by SAUER, John-Michael, RING, Barbara J, WITCHER, Jennifer W
Published in Clinical pharmacokinetics (01.01.2005)

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Hepatic CYP2B6 Expression: Gender and Ethnic Differences and Relationship to CYP2B6 Genotype and CAR (Constitutive Androstane Receptor) Expression

Hepatic CYP2B6 Expression: Gender and Ethnic Differences and Relationship to CYP2B6 Genotype and CAR (Constitutive Androstane Receptor) Expression

by Lamba, Vishal, Lamba, Jatinder, Yasuda, Kazuto, Strom, Stephen, Davila, Julio, Hancock, Michael L, Fackenthal, James D, Rogan, Peter K, Ring, Barbara, Wrighton, Steven A, Schuetz, Erin G
Published in The Journal of pharmacology and experimental therapeutics (01.12.2003)

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PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 4: Prediction of plasma concentration–time profiles in human from in vivo preclinical data by using the Wajima approach

PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 4: Prediction of plasma concentration–time profiles in human from in vivo preclinical data by using the Wajima approach

by Vuppugalla, Ragini, Marathe, Punit, He, Handan, Jones, Rhys D.O., Yates, James W.T., Jones, Hannah M., Gibson, Christopher R., Chien, Jenny Y., Ring, Barbara J., Adkison, Kimberly K., Ku, M. Sherry, Fischer, Volker, Dutta, Sandeep, Sinha, Vikash K., Björnsson, Thorir, Lavé, Thierry, Poulin, Patrick
Published in Journal of pharmaceutical sciences (01.10.2011)

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THE EFFECT OF INCUBATION CONDITIONS ON THE ENZYME KINETICS OF UDP-GLUCURONOSYLTRANSFERASES

THE EFFECT OF INCUBATION CONDITIONS ON THE ENZYME KINETICS OF UDP-GLUCURONOSYLTRANSFERASES

by SOARS, Matthew G, RING, Barbara J, WRIGHTON, Steven A
Published in Drug metabolism and disposition (01.06.2003)

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Pharmacogenomics of gemcitabine metabolism: functional analysis of genetic variants in cytidine deaminase and deoxycytidine kinase

Pharmacogenomics of gemcitabine metabolism: functional analysis of genetic variants in cytidine deaminase and deoxycytidine kinase

by Baker, Jessica A Roseberry, Wickremsinhe, Enaksha R, Li, Claire H, Oluyedun, Olukayode A, Dantzig, Anne H, Hall, Stephen D, Qian, Yue-Wei, Ring, Barbara J, Wrighton, Steven A, Guo, Yingying
Published in Drug metabolism and disposition (01.03.2013)

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PhRMA CPCDC Initiative on Predictive Models of Human Pharmacokinetics, Part 1: Goals, Properties of the Phrma Dataset, and Comparison with Literature Datasets

PhRMA CPCDC Initiative on Predictive Models of Human Pharmacokinetics, Part 1: Goals, Properties of the Phrma Dataset, and Comparison with Literature Datasets

by Poulin, Patrick, Jones, Hannah M., Jones, Rhys Do, Yates, James W.T., Gibson, Christopher R., Chien, Jenny Y., Ring, Barbara J., Adkison, Kimberly K., He, Handan, Vuppugalla, Ragini, Marathe, Punit, Fischer, Volker, Dutta, Sandeep, Sinha, Vikash K., Björnsson, Thorir, Lavé, Thierry, Sherry Ku, M.
Published in Journal of pharmaceutical sciences (01.10.2011)

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Disposition and Metabolism of Semagacestat, a γ-Secretase Inhibitor, in Humans

Disposition and Metabolism of Semagacestat, a γ-Secretase Inhibitor, in Humans

by PING YI, HADDEN, Chad, KULANTHAIVEL, Palaniappan, CALVERT, Nathan, ANNES, William, BROWN, Thomas, BARBUCH, Robert J, CHAUDHARY, Archana, AYAN-OSHODI, Mosun A, RING, Barbara J
Published in Drug metabolism and disposition (01.04.2010)

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Differential Modulation of UDP-Glucuronosyltransferase 1A1 (UGT1A1)-Catalyzed Estradiol-3-glucuronidation by the Addition of UGT1A1 Substrates and Other Compounds to Human Liver Microsomes

Differential Modulation of UDP-Glucuronosyltransferase 1A1 (UGT1A1)-Catalyzed Estradiol-3-glucuronidation by the Addition of UGT1A1 Substrates and Other Compounds to Human Liver Microsomes

by WILLIAMS, J. Andrew, RING, Barbara J, CANTRELL, Varon E, CAMPANALE, Kristina, JONES, David R, HALL, Stephen D, WRIGHTON, Steven A
Published in Drug metabolism and disposition (01.11.2002)

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Predictions of the in vivo clearance of drugs from rate of loss using human liver microsomes for phase I and phase II biotransformations

Predictions of the in vivo clearance of drugs from rate of loss using human liver microsomes for phase I and phase II biotransformations

by MOHUTSKY, Michael A, CHIEN, Jenny Y, RING, Barbara J, WRIGHTON, Steven A
Published in Pharmaceutical research (01.04.2006)

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Identification of the Human Cytochromes P450 Responsible for Atomoxetine Metabolism

Identification of the Human Cytochromes P450 Responsible for Atomoxetine Metabolism

by RING, Barbara J, GILLESPIE, Jennifer S, ECKSTEIN, James A, WRIGHTON, Steven A
Published in Drug metabolism and disposition (01.03.2002)

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Effect of tadalafil on cytochrome P450 3A4-mediated clearance: studies in vitro and in vivo

Effect of tadalafil on cytochrome P450 3A4-mediated clearance: studies in vitro and in vivo

by Ring, Barbara J, Patterson, Beverley E, Mitchell, Malcolm I, Vandenbranden, Mark, Gillespie, Jennifer, Bedding, Alun W, Jewell, Hayley, Payne, Christopher D, Forgue, S Thomas, Eckstein, James, Wrighton, Steven A, Phillips, Diane L
Published in Clinical pharmacology and therapeutics (01.01.2005)

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NEW CYTOCHROME P450 2D656 ALLELE IDENTIFIED BY GENOTYPE/PHENOTYPE ANALYSIS OF CRYOPRESERVED HUMAN HEPATOCYTES

NEW CYTOCHROME P450 2D656 ALLELE IDENTIFIED BY GENOTYPE/PHENOTYPE ANALYSIS OF CRYOPRESERVED HUMAN HEPATOCYTES

by LI LI, PAN, Run-Mei, PORTER, Todd D, JENSEN, Neil S, SILBER, Paul, RUSSO, Guy, TINE, John A, HEIM, John, RING, Barbara, WEDLUND, Peter J
Published in Drug metabolism and disposition (01.08.2006)

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Atomoxetine Hydrochloride: Clinical Drug-Drug Interaction Prediction and Outcome

Atomoxetine Hydrochloride: Clinical Drug-Drug Interaction Prediction and Outcome

by Sauer, John-Michael, Long, Amanda J, Ring, Barbara, Gillespie, Jennifer S, Sanburn, Nathan P, DeSante, Karl A, Petullo, David, VandenBranden, Mark R, Jensen, Charles B, Wrighton, Steven A, Smith, Brian P, Read, Holly A, Witcher, Jennifer W
Published in The Journal of pharmacology and experimental therapeutics (01.02.2004)

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Three- and Four-Dimensional Quantitative Structure Activity Relationship Analyses of Cytochrome P-450 3A4 Inhibitors

Three- and Four-Dimensional Quantitative Structure Activity Relationship Analyses of Cytochrome P-450 3A4 Inhibitors

by Ekins, S, Bravi, G, Binkley, S, Gillespie, J S, Ring, B J, Wikel, J H, Wrighton, S A
Published in The Journal of pharmacology and experimental therapeutics (01.07.1999)

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