Sensing R-Loop-Associated DNA Damage to Safeguard Genome Stability
Rinaldi, Carlo, Pizzul, Paolo, Longhese, Maria Pia, Bonetti, Diego
Published in Frontiers in cell and developmental biology (11.01.2021)
Published in Frontiers in cell and developmental biology (11.01.2021)
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Journal Article
Beyond motor neurons: expanding the clinical spectrum in Kennedy’s disease
Manzano, Raquel, Sorarú, Gianni, Grunseich, Christopher, Fratta, Pietro, Zuccaro, Emanuela, Pennuto, Maria, Rinaldi, Carlo
Published in Journal of neurology, neurosurgery and psychiatry (01.08.2018)
Published in Journal of neurology, neurosurgery and psychiatry (01.08.2018)
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Journal Article
The PP2A phosphatase counteracts the function of the 9-1-1 axis in checkpoint activation
Casari, Erika, Pizzul, Paolo, Rinaldi, Carlo, Gnugnoli, Marco, Clerici, Michela, Longhese, Maria Pia
Published in Cell reports (Cambridge) (28.11.2023)
Published in Cell reports (Cambridge) (28.11.2023)
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Journal Article
The DNA damage checkpoint: A tale from budding yeast
Pizzul, Paolo, Casari, Erika, Gnugnoli, Marco, Rinaldi, Carlo, Corallo, Flavio, Longhese, Maria Pia
Published in Frontiers in genetics (15.09.2022)
Published in Frontiers in genetics (15.09.2022)
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Journal Article
LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice
Prakasam, Ramachandran, Bonadiman, Angela, Andreotti, Roberta, Zuccaro, Emanuela, Dalfovo, Davide, Marchioretti, Caterina, Tripathy, Debasmita, Petris, Gianluca, Anderson, Eric N., Migazzi, Alice, Tosatto, Laura, Cereseto, Anna, Battaglioli, Elena, Sorarù, Gianni, Lim, Wooi Fang, Rinaldi, Carlo, Sambataro, Fabio, Pourshafie, Naemeh, Grunseich, Christopher, Romanel, Alessandro, Pandey, Udai Bhan, Contestabile, Andrea, Ronzitti, Giuseppe, Basso, Manuela, Pennuto, Maria
Published in Nature communications (06.02.2023)
Published in Nature communications (06.02.2023)
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Journal Article
PRMT inhibitor promotes SMN2 exon 7 inclusion and synergizes with nusinersen to rescue SMA mice
Kordala, Anna J, Stoodley, Jessica, Ahlskog, Nina, Hanifi, Muhammad, Garcia Guerra, Antonio, Bhomra, Amarjit, Lim, Wooi Fang, Murray, Lyndsay M, Talbot, Kevin, Hammond, Suzan M, Wood, Matthew JA, Rinaldi, Carlo
Published in EMBO molecular medicine (08.11.2023)
Published in EMBO molecular medicine (08.11.2023)
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Journal Article
A small-molecule Nrf1 and Nrf2 activator mitigates polyglutamine toxicity in spinal and bulbar muscular atrophy
Bott, Laura C, Badders, Nisha M, Chen, Ke-Lian, Harmison, George G, Bautista, Elaine, Shih, Charles C-Y, Katsuno, Masahisa, Sobue, Gen, Taylor, J Paul, Dantuma, Nico P, Fischbeck, Kenneth H, Rinaldi, Carlo
Published in Human molecular genetics (15.05.2016)
Published in Human molecular genetics (15.05.2016)
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Journal Article
To Fix or Not to Fix: Maintenance of Chromosome Ends Versus Repair of DNA Double-Strand Breaks
Casari, Erika, Gnugnoli, Marco, Rinaldi, Carlo, Pizzul, Paolo, Colombo, Chiara Vittoria, Bonetti, Diego, Longhese, Maria Pia
Published in Cells (Basel, Switzerland) (01.10.2022)
Published in Cells (Basel, Switzerland) (01.10.2022)
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Journal Article
Processing of DNA Double-Strand Breaks by the MRX Complex in a Chromatin Context
Casari, Erika, Rinaldi, Carlo, Marsella, Antonio, Gnugnoli, Marco, Colombo, Chiara Vittoria, Bonetti, Diego, Longhese, Maria Pia
Published in Frontiers in molecular biosciences (07.06.2019)
Published in Frontiers in molecular biosciences (07.06.2019)
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Journal Article
The Role of the Protein Quality Control System in SBMA
Rusmini, Paola, Crippa, Valeria, Cristofani, Riccardo, Rinaldi, Carlo, Cicardi, Maria Elena, Galbiati, Mariarita, Carra, Serena, Malik, Bilal, Greensmith, Linda, Poletti, Angelo
Published in Journal of molecular neuroscience (01.03.2016)
Published in Journal of molecular neuroscience (01.03.2016)
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Journal Article
MiR-298 Counteracts Mutant Androgen Receptor Toxicity in Spinal and Bulbar Muscular Atrophy
Pourshafie, Naemeh, Lee, Philip R, Chen, Ke-lian, Harmison, George G, Bott, Laura C, Katsuno, Masahisa, Sobue, Gen, Burnett, Barrington G, Fischbeck, Kenneth H, Rinaldi, Carlo
Published in Molecular therapy (01.05.2016)
Published in Molecular therapy (01.05.2016)
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Journal Article
Polyglutamine-Expanded Androgen Receptor Alteration of Skeletal Muscle Homeostasis and Myonuclear Aggregation Are Affected by Sex, Age and Muscle Metabolism
Chivet, Mathilde, Marchioretti, Caterina, Pirazzini, Marco, Piol, Diana, Scaramuzzino, Chiara, Polanco, Maria Josè, Romanello, Vanina, Zuccaro, Emanuela, Parodi, Sara, D'Antonio, Maurizio, Rinaldi, Carlo, Sambataro, Fabio, Pegoraro, Elena, Soraru, Gianni, Pandey, Udai Bhan, Sandri, Marco, Basso, Manuela, Pennuto, Maria
Published in Cells (Basel, Switzerland) (30.01.2020)
Published in Cells (Basel, Switzerland) (30.01.2020)
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Journal Article
Targeting the 5′ untranslated region of SMN2 as a therapeutic strategy for spinal muscular atrophy
Winkelsas, Audrey M., Grunseich, Christopher, Harmison, George G., Chwalenia, Katarzyna, Rinaldi, Carlo, Hammond, Suzan M., Johnson, Kory, Bowerman, Melissa, Arya, Sukrat, Talbot, Kevin, Wood, Matthew J., Fischbeck, Kenneth H.
Published in Molecular therapy. Nucleic acids (05.03.2021)
Published in Molecular therapy. Nucleic acids (05.03.2021)
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Journal Article
Insulinlike growth factor (IGF)-1 administration ameliorates disease manifestations in a mouse model of spinal and bulbar muscular atrophy
Rinaldi, Carlo, Bott, Laura C, Chen, Ke-lian, Harmison, George G, Katsuno, Masahisa, Sobue, Gen, Pennuto, Maria, Fischbeck, Kenneth H
Published in Molecular medicine (Cambridge, Mass.) (2012)
Published in Molecular medicine (Cambridge, Mass.) (2012)
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Journal Article
Benign hereditary chorea: Clinical and neuroimaging features in an Italian family
Salvatore, Elena, Di Maio, Luigi, Filla, Alessandro, Ferrara, Alfonso M., Rinaldi, Carlo, Saccà, Francesco, Peluso, Silvio, Macchia, Paolo E., Pappatà, Sabina, De Michele, Giuseppe
Published in Movement disorders (30.07.2010)
Published in Movement disorders (30.07.2010)
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Journal Article
Blood vessel remodeling in pig ovarian follicles during the periovulatory period: an immunohistochemistry and SEM-corrosion casting study
Martelli, Alessandra, Palmerini, Maria Grazia, Russo, Valentina, Rinaldi, Carlo, Bernabò, Nicola, Di Giacinto, Oriana, Berardinelli, Paolo, Nottola, Stefania Annarita, Macchiarelli, Guido, Barboni, Barbara
Published in Reproductive biology and endocrinology (16.07.2009)
Published in Reproductive biology and endocrinology (16.07.2009)
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Journal Article
Stem cell-derived motor neurons from spinal and bulbar muscular atrophy patients
Grunseich, Christopher, Zukosky, Kristen, Kats, Ilona R, Ghosh, Laboni, Harmison, George G, Bott, Laura C, Rinaldi, Carlo, Chen, Ke-lian, Chen, Guibin, Boehm, Manfred, Fischbeck, Kenneth H
Published in Neurobiology of disease (01.10.2014)
Published in Neurobiology of disease (01.10.2014)
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