Structure Based Prediction of Neoantigen Immunogenicity
Riley, Timothy P, Keller, Grant L J, Smith, Angela R, Davancaze, Lauren M, Arbuiso, Alyssa G, Devlin, Jason R, Baker, Brian M
Published in Frontiers in immunology (28.08.2019)
Published in Frontiers in immunology (28.08.2019)
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Journal Article
Enhancing the Prefusion Conformational Stability of SARS-CoV-2 Spike Protein Through Structure-Guided Design
Riley, Timothy P, Chou, Hui-Ting, Hu, Ruozhen, Bzymek, Krzysztof P, Correia, Ana R, Partin, Alexander C, Li, Danqing, Gong, Danyang, Wang, Zhulun, Yu, Xinchao, Manzanillo, Paolo, Garces, Fernando
Published in Frontiers in immunology (22.04.2021)
Published in Frontiers in immunology (22.04.2021)
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Journal Article
How structural adaptability exists alongside HLA-A2 bias in the human αβ TCR repertoire
Blevins, Sydney J., Pierce, Brian G., Singh, Nishant K., Riley, Timothy P., Wang, Yuan, Spear, Timothy T., Nishimura, Michael I., Weng, Zhiping, Baker, Brian M.
Published in Proceedings of the National Academy of Sciences - PNAS (01.03.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (01.03.2016)
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Journal Article
Geometric parameters that affect the behavior of logic-gated CAR T cells
Partin, Alexander C, Bruno, Richele, Shafaattalab, Sanam, Vander Mause, Erica, Winters, Aaron, Daris, Mark, Gahrs, Casey, Jette, Claudia A, DiAndreth, Breanna, Sandberg, Mark L, Hamburger, Agnes E, Kamb, Alexander, Riley, Timothy P
Published in Frontiers in immunology (2024)
Published in Frontiers in immunology (2024)
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Journal Article
Toward generalizable prediction of antibody thermostability using machine learning on sequence and structure features
Harmalkar, Ameya, Rao, Roshan, Richard Xie, Yuxuan, Honer, Jonas, Deisting, Wibke, Anlahr, Jonas, Hoenig, Anja, Czwikla, Julia, Sienz-Widmann, Eva, Rau, Doris, Rice, Austin J, Riley, Timothy P, Li, Danqing, Catterall, Hannah B, Tinberg, Christine E, Gray, Jeffrey J, Wei, Kathy Y
Published in mAbs (2023)
Published in mAbs (2023)
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Journal Article
Rational selection of building blocks for the assembly of bispecific antibodies
Gong, Danyang, Riley, Timothy P, Bzymek, Krzysztof P, Correia, Ana R, Li, Danqing, Spahr, Christopher, Robinson, John H, Case, Ryan B, Wang, Zhulun, Garces, Fernando
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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Journal Article
Next generation Fc scaffold for multispecific antibodies
Estes, Bram, Sudom, Athena, Gong, Danyang, Whittington, Douglas A., Li, Vivian, Mohr, Christopher, Li, Danqing, Riley, Timothy P., Shi, Stone D.-H., Zhang, Jun, Garces, Fernando, Wang, Zhulun
Published in iScience (17.12.2021)
Published in iScience (17.12.2021)
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Journal Article
Protocol for high-throughput cloning, expression, purification, and evaluation of bispecific antibodies
Li, Danqing, Partin, Alexander C., Zhao, Liangjun, Chen, Irwin, Michaels, Mark L., Wang, Zhulun, Garces, Fernando, Gong, Danyang, Riley, Timothy P.
Published in STAR protocols (17.06.2022)
Published in STAR protocols (17.06.2022)
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Journal Article
HLA-A∗02-gated safety switch for cancer therapy has exquisite specificity for its allelic target antigen
Mock, Jee-Young, Winters, Aaron, Riley, Timothy P., Bruno, Richele, Naradikian, Martin S., Sharma, Shruti, Jette, Claudia A., Elshimali, Ryan, Gahrs, Casey, Toledo-Warshaviak, Dora, West, Anthony P., Kamb, Alexander, Hamburger, Agnes E.
Published in Molecular therapy. Oncolytics (15.12.2022)
Published in Molecular therapy. Oncolytics (15.12.2022)
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Journal Article
T cell receptor cross-reactivity expanded by dramatic peptide–MHC adaptability
Riley, Timothy P., Hellman, Lance M., Gee, Marvin H., Mendoza, Juan L., Alonso, Jesus A., Foley, Kendra C., Nishimura, Michael I., Vander Kooi, Craig W., Garcia, K. Christopher, Baker, Brian M.
Published in Nature chemical biology (01.10.2018)
Published in Nature chemical biology (01.10.2018)
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Journal Article
Improving T Cell Receptor On-Target Specificity via Structure-Guided Design
Hellman, Lance M., Foley, Kendra C., Singh, Nishant K., Alonso, Jesus A., Riley, Timothy P., Devlin, Jason R., Ayres, Cory M., Keller, Grant L.J., Zhang, Yuting, Vander Kooi, Craig W., Nishimura, Michael I., Baker, Brian M.
Published in Molecular therapy (06.02.2019)
Published in Molecular therapy (06.02.2019)
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Journal Article
TRPM3 expression and control of glutamate release from primary vagal afferent neurons
Ragozzino, Forrest J, Arnold, Rachel A, Fenwick, Axel J, Riley, Timothy P, Lindberg, Jonathan E M, Peterson, BreeAnne, Peters, James H
Published in Journal of neurophysiology (01.01.2021)
Published in Journal of neurophysiology (01.01.2021)
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Journal Article
Deep Mutational Scans as a Guide to Engineering High Affinity T Cell Receptor Interactions with Peptide-bound Major Histocompatibility Complex
Harris, Daniel T., Wang, Ningyan, Riley, Timothy P., Anderson, Scott D., Singh, Nishant K., Procko, Erik, Baker, Brian M., Kranz, David M.
Published in The Journal of biological chemistry (18.11.2016)
Published in The Journal of biological chemistry (18.11.2016)
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Journal Article
Differential scanning fluorimetry based assessments of the thermal and kinetic stability of peptide–MHC complexes
Hellman, Lance M., Yin, Liusong, Wang, Yuan, Blevins, Sydney J., Riley, Timothy P., Belden, Orrin S., Spear, Timothy T., Nishimura, Michael I., Stern, Lawrence J., Baker, Brian M.
Published in Journal of immunological methods (01.05.2016)
Published in Journal of immunological methods (01.05.2016)
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Journal Article
Modeling Sequence-Dependent Peptide Fluctuations in Immunologic Recognition
Ayres, Cory M, Riley, Timothy P, Corcelli, Steven A, Baker, Brian M
Published in Journal of chemical information and modeling (28.08.2017)
Published in Journal of chemical information and modeling (28.08.2017)
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Journal Article
Computational Modeling of T Cell Receptor Complexes
Riley, Timothy P, Singh, Nishant K, Pierce, Brian G, Weng, Zhiping, Baker, Brian M
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2016)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2016)
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Journal Article
A generalized framework for computational design and mutational scanning of T-cell receptor binding interfaces
Riley, Timothy P, Ayres, Cory M, Hellman, Lance M, Singh, Nishant K, Cosiano, Michael, Cimons, Jennifer M, Anderson, Michael J, Piepenbrink, Kurt H, Pierce, Brian G, Weng, Zhiping, Baker, Brian M
Published in Protein engineering, design and selection (01.12.2016)
Published in Protein engineering, design and selection (01.12.2016)
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Journal Article
Molecular properties of gp100‐reactive T‐cell receptors drive the cytokine profile and antitumor efficacy of transgenic host T cells
Eby, Jonathan M., Smith, Angela R., Riley, Timothy P., Cosgrove, Cormac, Ankney, Christian M., Henning, Steven W., Paulos, Chrystal M., Garrett‐Mayer, Elizabeth, Luiten, Rosalie M., Nishimura, Michael I., Baker, Brian M., Le Poole, I. Caroline
Published in Pigment cell and melanoma research (01.01.2019)
Published in Pigment cell and melanoma research (01.01.2019)
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Journal Article