Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms
Hu, Haichuan, Piotrowska, Zofia, Hare, Patricia J., Chen, Huidong, Mulvey, Hillary E., Mayfield, Aislinn, Noeen, Sundus, Kattermann, Krystina, Greenberg, Max, Williams, August, Riley, Amanda K., Wilson, Jarad J., Mao, Ying-Qing, Huang, Ruo-Pan, Banwait, Mandeep K., Ho, Jeffrey, Crowther, Giovanna S., Hariri, Lida P., Heist, Rebecca S., Kodack, David P., Pinello, Luca, Shaw, Alice T., Mino-Kenudson, Mari, Hata, Aaron N., Sequist, Lecia V., Benes, Cyril H., Niederst, Matthew J., Engelman, Jeffrey A.
Published in Cancer cell (08.11.2021)
Published in Cancer cell (08.11.2021)
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Sequential ALK Inhibitors Can Select for Lorlatinib-Resistant Compound ALK Mutations in ALK-Positive Lung Cancer
Yoda, Satoshi, Lin, Jessica J, Lawrence, Michael S, Burke, Benjamin J, Friboulet, Luc, Langenbucher, Adam, Dardaei, Leila, Prutisto-Chang, Kylie, Dagogo-Jack, Ibiayi, Timofeevski, Sergei, Hubbeling, Harper, Gainor, Justin F, Ferris, Lorin A, Riley, Amanda K, Kattermann, Krystina E, Timonina, Daria, Heist, Rebecca S, Iafrate, A John, Benes, Cyril H, Lennerz, Jochen K, Mino-Kenudson, Mari, Engelman, Jeffrey A, Johnson, Ted W, Hata, Aaron N, Shaw, Alice T
Published in Cancer discovery (01.06.2018)
Published in Cancer discovery (01.06.2018)
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Primary Patient-Derived Cancer Cells and Their Potential for Personalized Cancer Patient Care
Kodack, David P., Farago, Anna F., Dastur, Anahita, Held, Matthew A., Dardaei, Leila, Friboulet, Luc, von Flotow, Friedrich, Damon, Leah J., Lee, Dana, Parks, Melissa, Dicecca, Richard, Greenberg, Max, Kattermann, Krystina E., Riley, Amanda K., Fintelmann, Florian J., Rizzo, Coleen, Piotrowska, Zofia, Shaw, Alice T., Gainor, Justin F., Sequist, Lecia V., Niederst, Matthew J., Engelman, Jeffrey A., Benes, Cyril H.
Published in Cell reports (Cambridge) (12.12.2017)
Published in Cell reports (Cambridge) (12.12.2017)
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Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer
Vichas, Athea, Riley, Amanda K, Nkinsi, Naomi T, Kamlapurkar, Shriya, Parrish, Phoebe C R, Lo, April, Duke, Fujiko, Chen, Jennifer, Fung, Iris, Watson, Jacqueline, Rees, Matthew, Gabel, Austin M, Thomas, James D, Bradley, Robert K, Lee, John K, Hatch, Emily M, Baine, Marina K, Rekhtman, Natasha, Ladanyi, Marc, Piccioni, Federica, Berger, Alice H
Published in Nature communications (09.08.2021)
Published in Nature communications (09.08.2021)
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The deubiquitinase USP9X regulates RIT1 protein abundance and oncogenic phenotypes
Riley, Amanda K., Grant, Michael, Snell, Aidan, Cromwell, Elizabeth, Vichas, Athea, Moorthi, Sitapriya, Rominger, Callie, Modukuri, Shrikar P., Urisman, Anatoly, Castel, Pau, Wan, Lixin, Berger, Alice H.
Published in iScience (16.08.2024)
Published in iScience (16.08.2024)
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Landscape of Acquired Resistance to Osimertinib in EGFR -Mutant NSCLC and Clinical Validation of Combined EGFR and RET Inhibition with Osimertinib and BLU-667 for Acquired RET Fusion
Piotrowska, Zofia, Isozaki, Hideko, Lennerz, Jochen K, Gainor, Justin F, Lennes, Inga T, Zhu, Viola W, Marcoux, Nicolas, Banwait, Mandeep K, Digumarthy, Subba R, Su, Wenjia, Yoda, Satoshi, Riley, Amanda K, Nangia, Varuna, Lin, Jessica J, Nagy, Rebecca J, Lanman, Richard B, Dias-Santagata, Dora, Mino-Kenudson, Mari, Iafrate, A John, Heist, Rebecca S, Shaw, Alice T, Evans, Erica K, Clifford, Corinne, Ou, Sai-Hong I, Wolf, Beni, Hata, Aaron N, Sequist, Lecia V
Published in Cancer discovery (01.12.2018)
Published in Cancer discovery (01.12.2018)
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Hepatic Responses of Juvenile Fundulus heteroclitus from Pollution-adapted and Nonadapted Populations Exposed to Elizabeth River Sediment Extract
Riley, Amanda K, Chernick, Melissa, Brown, Daniel R, Hinton, David E, Di Giulio, Richard T
Published in Toxicologic pathology (01.07.2016)
Published in Toxicologic pathology (01.07.2016)
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Abstract 2972: Identification of USP9X as a novel regulator of RIT1 protein abundance and as a potential therapeutic target in RIT1 -driven lung cancer
Riley, Amanda K., Vichas, Athea, Nkinsi, Naomi T., Parrish, Phoebe C., Kamlapurkar, Shriya, Berger, Alice H.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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The deubiquitinase USP9X regulates RIT1 protein abundance and oncogenic phenotypes
Riley, Amanda K, Grant, Michael, Snell, Aidan, Vichas, Athea, Moorthi, Sitapriya, Urisman, Anatoly, Castel, Pau, Wan, Lixin, Berger, Alice H
Published in bioRxiv : the preprint server for biology (01.12.2023)
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Published in bioRxiv : the preprint server for biology (01.12.2023)
Journal Article
The deubiquitinase USP9X regulates RIT1 protein abundance and oncogenic phenotypes
Riley, Amanda K, Grant, Michael, Snell, Aidan, Vichas, Athea, Moorthi, Sitapriya, Urisman, Anatoly, Castel, Pau, Wan, Lixin, Berger, Alice
Published in bioRxiv (01.12.2023)
Published in bioRxiv (01.12.2023)
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