Drug screen in patient cells suggests quinacrine to be repositioned for treatment of acute myeloid leukemia
Eriksson, A, Österroos, A, Hassan, S, Gullbo, J, Rickardson, L, Jarvius, M, Nygren, P, Fryknäs, M, Höglund, M, Larsson, R
Published in Blood cancer journal (New York) (17.04.2015)
Published in Blood cancer journal (New York) (17.04.2015)
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Journal Article
Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles
RICKARDSON, L, FRYKNÄS, M, DHAR, S, LÖVBORG, H, GULLBO, J, RYDAKER, M, NYGREN, P, GUSTAFSSON, M. G, LARSSON, R, ISAKSSON, A
Published in British journal of cancer (22.08.2005)
Published in British journal of cancer (22.08.2005)
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Journal Article
Screening for phenotype selective activity in multidrug resistant cells identifies a novel tubulin active agent insensitive to common forms of cancer drug resistance
Fryknäs, Mårten, Gullbo, Joachim, Wang, Xin, Rickardson, Linda, Jarvius, Malin, Wickström, Malin, Hassan, Saadia, Andersson, Claes, Gustafsson, Mats, Westman, Gunnar, Nygren, Peter, Linder, Stig, Larsson, Rolf
Published in BMC cancer (06.08.2013)
Published in BMC cancer (06.08.2013)
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Journal Article
Phenotype-based drug screening in primary ovarian carcinoma cultures identifies intracellular iron depletion as a promising strategy for cancer treatment
Gullbo, Joachim, Fryknäs, Mårten, Rickardson, Linda, Darcy, Padraig, Hägg, Maria, Wickström, Malin, Hassan, Sadia, Westman, Gunnar, Brnjic, Slavica, Nygren, Peter, Linder, Stig, Larsson, Rolf
Published in Biochemical pharmacology (2011)
Published in Biochemical pharmacology (2011)
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Journal Article
127 Identification of CB3, a novel inhibitor of the ubiquitin-proteasome system
Haglund, C, Fryknäs, M, Larsson, R, Linder, S, Rickardson, L
Published in European journal of cancer supplements (2010)
Published in European journal of cancer supplements (2010)
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Journal Article
Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments
Zhang, Xiaonan, Fryknäs, Mårten, Hernlund, Emma, Fayad, Walid, De Milito, Angelo, Olofsson, Maria Hägg, Gogvadze, Vladimir, Dang, Long, Påhlman, Sven, Schughart, Leoni A. Kunz, Rickardson, Linda, D′Arcy, Padraig, Gullbo, Joachim, Nygren, Peter, Larsson, Rolf, Linder, Stig
Published in Nature communications (2014)
Published in Nature communications (2014)
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Journal Article
Piperlongumine induces inhibition of the ubiquitin–proteasome system in cancer cells
Jarvius, Malin, Fryknäs, Mårten, D’Arcy, Pädraig, Sun, Chao, Rickardson, Linda, Gullbo, Joachim, Haglund, Caroline, Nygren, Peter, Linder, Stig, Larsson, Rolf
Published in Biochemical and biophysical research communications (08.02.2013)
Published in Biochemical and biophysical research communications (08.02.2013)
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Journal Article
Inhibition of proteasome activity, nuclear factor‐KB translocation and cell survival by the antialcoholism drug disulfiram
Lövborg, Henrik, Öberg, Fredrik, Rickardson, Linda, Gullbo, Joachim, Nygren, Peter, Larsson, Rolf
Published in International journal of cancer (15.03.2006)
Published in International journal of cancer (15.03.2006)
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Journal Article
Cytotoxic Effects of Cardiac Glycosides in Colon Cancer Cells, Alone and in Combination with Standard Chemotherapeutic Drugs
Felth, Jenny, Rickardson, Linda, Rosén, Josefin, Wickström, Malin, Fryknäs, Mårten, Lindskog, Magnus, Bohlin, Lars, Gullbo, Joachim
Published in Journal of natural products (Washington, D.C.) (2009)
Published in Journal of natural products (Washington, D.C.) (2009)
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Journal Article
Novel activity of acriflavine against colorectal cancer tumor cells
Hassan, Saadia, Laryea, Daniel, Mahteme, Haile, Felth, Jenny, Fryknäs, Mårten, Fayad, Walid, Linder, Stig, Rickardson, Linda, Gullbo, Joachim, Graf, Wilhelm, Påhlman, Lars, Glimelius, Bengt, Larsson, Rolf, Nygren, Peter
Published in Cancer science (01.12.2011)
Published in Cancer science (01.12.2011)
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Journal Article
Evaluation of the antitumor activity of NOV202, a novel microtubule targeting and vascular disrupting agent
Rickardson, Linda, Kutvonen, Emma, Orasniemi, Satu, Högberg, Marita, Kallio, Marko J, Rehnmark, Stefan
Published in Drug design, development and therapy (01.01.2017)
Published in Drug design, development and therapy (01.01.2017)
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Journal Article
Identification of Agents that Induce Apoptosis of Multicellular Tumour Spheroids: Enrichment for Mitotic Inhibitors with Hydrophobic Properties
Fayad, Walid, Rickardson, Linda, Haglund, Caroline, Olofsson, Maria Hägg, D'Arcy, Padraig, Larsson, Rolf, Linder, Stig, Fryknäs, Mårten
Published in Chemical biology & drug design (01.10.2011)
Published in Chemical biology & drug design (01.10.2011)
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Journal Article
Induction of the lysosomal apoptosis pathway by inhibitors of the ubiquitin‐proteasome system
Berndtsson, Maria, Beaujouin, Melanie, Rickardson, Linda, Havelka, Aleksandra Mandic, Larsson, Rolf, Westman, Jacob, Liaudet‐Coopman, Emmanuelle, Linder, Stig
Published in International journal of cancer (15.03.2009)
Published in International journal of cancer (15.03.2009)
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Journal Article
Gambogic acid is cytotoxic to cancer cells through inhibition of the ubiquitin-proteasome system
Felth, Jenny, Lesiak-Mieczkowska, Karolina, D’Arcy, Padraig, Haglund, Caroline, Gullbo, Joachim, Larsson, Rolf, Linder, Stig, Bohlin, Lars, Fryknäs, Mårten, Rickardson, Linda
Published in Investigational new drugs (01.06.2013)
Published in Investigational new drugs (01.06.2013)
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Journal Article
Stat1 activation attenuates IL-6 induced Stat3 activity but does not alter apoptosis sensitivity in multiple myeloma
Dimberg, Lina Y, Dimberg, Anna, Ivarsson, Karolina, Fryknäs, Mårten, Rickardson, Linda, Tobin, Gerard, Ekman, Simon, Larsson, Rolf, Gullberg, Urban, Nilsson, Kenneth, Öberg, Fredrik, Wiklund, Helena Jernberg
Published in BMC cancer (28.07.2012)
Published in BMC cancer (28.07.2012)
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Journal Article
Screening for Cytotoxic Compounds in Poor-prognostic Chronic Lymphocytic Leukemia
NORBERG, Maria, LINDHAGEN, Elin, KANDURI, Meena, RICKARDSON, Linda, SUNDSTRÖM, Christer, STAMATOPOULOS, Kostas, ROSENQUIST, Richard, ALESKOG, Anna
Published in Anticancer research (01.08.2012)
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Published in Anticancer research (01.08.2012)
Journal Article
Identification of an inhibitor of the ubiquitin-proteasome system that induces accumulation of polyubiquitinated proteins in the absence of blocking of proteasome function
Haglund, Caroline, Mohanty, Chitralekha, Fryknäs, Mårten, D'Arcy, Padraig, Larsson, Rolf, Linder, Stig, Rickardson, Linda
Published in MedChemComm (2014)
Published in MedChemComm (2014)
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Journal Article
Image-based screening for the identification of novel proteasome inhibitors
Rickardson, Linda, Wickström, Malin, Larsson, Rolf, Lövborg, Henrik
Published in Journal of biomolecular screening (01.03.2007)
Published in Journal of biomolecular screening (01.03.2007)
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Journal Article