Trimethylamine-N-Oxide Promotes Age-Related Vascular Oxidative Stress and Endothelial Dysfunction in Mice and Healthy Humans
Brunt, Vienna E, Gioscia-Ryan, Rachel A, Casso, Abigail G, VanDongen, Nicholas S, Ziemba, Brian P, Sapinsley, Zachary J, Richey, James J, Zigler, Melanie C, Neilson, Andrew P, Davy, Kevin P, Seals, Douglas R
Published in Hypertension (Dallas, Tex. 1979) (01.07.2020)
Published in Hypertension (Dallas, Tex. 1979) (01.07.2020)
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Suppression of the gut microbiome ameliorates age‐related arterial dysfunction and oxidative stress in mice
Brunt, Vienna E., Gioscia‐Ryan, Rachel A., Richey, James J., Zigler, Melanie C., Cuevas, Lauren M., Gonzalez, Antonio, Vázquez‐Baeza, Yoshiki, Battson, Micah L., Smithson, Andrew T., Gilley, Andrew D., Ackermann, Gail, Neilson, Andrew P., Weir, Tiffany, Davy, Kevin P., Knight, Rob, Seals, Douglas R.
Published in The Journal of physiology (01.05.2019)
Published in The Journal of physiology (01.05.2019)
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Gut Microbiome-Derived Metabolite Trimethylamine N-Oxide Induces Aortic Stiffening and Increases Systolic Blood Pressure With Aging in Mice and Humans
Brunt, Vienna E, Casso, Abigail G, Gioscia-Ryan, Rachel A, Sapinsley, Zachary J, Ziemba, Brian P, Clayton, Zachary S, Bazzoni, Amy E, VanDongen, Nicholas S, Richey, James J, Hutton, David A, Zigler, Melanie C, Neilson, Andrew P, Davy, Kevin P, Seals, Douglas R
Published in Hypertension (Dallas, Tex. 1979) (01.08.2021)
Published in Hypertension (Dallas, Tex. 1979) (01.08.2021)
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Lifelong voluntary aerobic exercise prevents age‐ and Western diet‐ induced vascular dysfunction, mitochondrial oxidative stress and inflammation in mice
Gioscia‐Ryan, Rachel A., Clayton, Zachary S., Zigler, Melanie C., Richey, James J., Cuevas, Lauren M., Rossman, Matthew J., Battson, Micah L., Ziemba, Brian P., Hutton, David A., VanDongen, Nicholas S., Seals, Douglas R.
Published in The Journal of physiology (01.02.2021)
Published in The Journal of physiology (01.02.2021)
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Short-term time-restricted feeding is safe and feasible in non-obese healthy midlife and older adults
Martens, Christopher R., Rossman, Matthew J., Mazzo, Melissa R., Jankowski, Lindsey R., Nagy, Erzsebet E., Denman, Blair A., Richey, James J., Johnson, Sarah A., Ziemba, Brian P., Wang, Yang, Peterson, Courtney M., Chonchol, Michel, Seals, Douglas R.
Published in GeroScience (01.04.2020)
Published in GeroScience (01.04.2020)
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Suppression of trimethylamine N-oxide with DMB mitigates vascular dysfunction, exercise intolerance, and frailty associated with a Western-style diet in mice
Brunt, Vienna E., Greenberg, Nathan T., Sapinsley, Zachary J., Casso, Abigail G., Richey, James J., VanDongen, Nicholas S., Gioscia-Ryan, Rachel A., Ziemba, Brian P., Neilson, Andrew P., Davy, Kevin P., Seals, Douglas R.
Published in Journal of applied physiology (1985) (01.10.2022)
Published in Journal of applied physiology (1985) (01.10.2022)
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Short‐term interleukin‐37 treatment improves vascular endothelial function, endurance exercise capacity, and whole‐body glucose metabolism in old mice
Ballak, Dov B., Brunt, Vienna E., Sapinsley, Zachary J., Ziemba, Brian P., Richey, James J., Zigler, Melanie C., Johnson, Lawrence C., Gioscia‐Ryan, Rachel A., Culp‐Hill, Rachel, Eisenmesser, Elan Z., D'Alessandro, Angelo, Dinarello, Charles A., Seals, Douglas R.
Published in Aging cell (01.01.2020)
Published in Aging cell (01.01.2020)
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2.7: The Gut-Derived Metabolite Trimethylamine N-Oxide Induces Large Elastic Artery Stiffening and Endothelial Dysfunction in Young Mice
Brunt, Vienna, Gioscia-Ryan, Rachel, Sapinsley, Zachary, Zigler, Melanie, Richey, James, Seals, Douglas
Published in Artery research (01.12.2017)
Published in Artery research (01.12.2017)
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Oral health as a gateway to overall health and well-being: Surveillance of the geriatric population in the United States
Hung, Man, Moffat, Ryan, Gill, Gagandeep, Lauren, Evelyn, Ruiz-Negrón, Bianca, Rosales, Megan N, Richey, James, Licari, Frank W
Published in Special care in dentistry (01.07.2019)
Published in Special care in dentistry (01.07.2019)
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The gut-derived metabolite trimethylamine N-oxide induces large elastic artery stiffening and endothelial dysfunction in young mice
Brunt, Vienna, Gioscia-Ryan, Rachel, Sapinsley, Zachary, Zigler, Melanie, Richey, James, Seals, Douglas
Published in Artery research (01.12.2017)
Published in Artery research (01.12.2017)
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2.7 THE GUT-DERIVED METABOLITE TRIMETHYLAMINE N-OXIDE INDUCES LARGE ELASTIC ARTERY STIFFENING AND ENDOTHELIAL DYSFUNCTION IN YOUNG MICE
Brunt, Vienna, Gioscia-Ryan, Rachel, Sapinsley, Zachary, Zigler, Melanie, Richey, James, Seals, Douglas
Published in Artery research (2017)
Published in Artery research (2017)
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