Endothelial TLR4 activation impairs intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS–NO–nitrite signaling
Yazji, Ibrahim, Sodhi, Chhinder P., Lee, Elizabeth K., Good, Misty, Egan, Charlotte E., Afrazi, Amin, Neal, Matthew D., Jia, Hongpeng, Lin, Joyce, Ma, Congrong, Branca, Maria F., Prindle, Thomas, Richardson, Ward M., Ozolek, John, Billiar, Timothy R., Binion, David G., Gladwin, Mark T., Hackam, David J.
Published in Proceedings of the National Academy of Sciences - PNAS (04.06.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (04.06.2013)
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A critical role for TLR4 induction of autophagy in the regulation of enterocyte migration and the pathogenesis of necrotizing enterocolitis
Neal, Matthew D, Sodhi, Chhinder P, Dyer, Mitchell, Craig, Brian T, Good, Misty, Jia, Hongpeng, Yazji, Ibrahim, Afrazi, Amin, Richardson, Ward M, Beer-Stolz, Donna, Ma, Congrong, Prindle, Thomas, Grant, Zachary, Branca, Maria F, Ozolek, John, Hackam, David J
Published in The Journal of immunology (1950) (01.04.2013)
Published in The Journal of immunology (1950) (01.04.2013)
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Recognizing life-threatening bleeding in pediatric trauma: A standard for when to activate massive transfusion protocol
Morgan, Katrina M, Gaines, Barbara A, Richardson, Ward M, Strotmeyer, Stephen, Leeper, Christine M
Published in The journal of trauma and acute care surgery (01.01.2023)
Published in The journal of trauma and acute care surgery (01.01.2023)
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Toll-like receptor-4 inhibits enterocyte proliferation via impaired beta-catenin signaling in necrotizing enterocolitis
Sodhi, Chhinder P, Shi, Xia-Hua, Richardson, Ward M, Grant, Zachary S, Shapiro, Richard A, Prindle, Jr, Thomas, Branca, Maria, Russo, Anthony, Gribar, Steven C, Ma, Congrong, Hackam, David J
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2010)
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2010)
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Reciprocal Expression and Signaling of TLR4 and TLR9 in the Pathogenesis and Treatment of Necrotizing Enterocolitis
Gribar, Steven C, Sodhi, Chhinder P, Richardson, Ward M, Anand, Rahul J, Gittes, George K, Branca, Maria F, Jakub, Adam, Shi, Xia-hua, Shah, Sohail, Ozolek, John A, Hackam, David J
Published in The Journal of immunology (1950) (01.01.2009)
Published in The Journal of immunology (1950) (01.01.2009)
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New Functional Impairment After Hospital Discharge by Traumatic Brain Injury Mechanism in Younger Than 3 Years Old Admitted to the PICU in a Single Center Retrospective Study
McNamara, Caitlin R, Kalinowski, Anne, Horvat, Christopher M, Gaines, Barbara A, Richardson, Ward M, Simon, Dennis W, Kochanek, Patrick M, Berger, Rachel P, Fink, Ericka L
Published in Pediatric critical care medicine (01.03.2024)
Published in Pediatric critical care medicine (01.03.2024)
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Association of Thromboelastography with Progression of Hemorrhagic Injury in Children with Traumatic Brain Injury
Abou Khalil, Elissa, Gaines, Barbara A., Kellogg, Robert G., Simon, Dennis W., Morgan, Katrina M., Richardson, Ward M., Leeper, Christine M.
Published in Neurocritical care (01.04.2023)
Published in Neurocritical care (01.04.2023)
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Journal Article
Multiorgan Dysfunction Syndrome in Abusive and Accidental Pediatric Traumatic Brain Injury
McNamara, Caitlin R., Even, Katelyn M., Kalinowski, Anne, Horvat, Christopher M., Gaines, Barbara A., Richardson, Ward M., Simon, Dennis W., Kochanek, Patrick M., Berger, Rachel P., Fink, Ericka L.
Published in Neurocritical care (01.06.2024)
Published in Neurocritical care (01.06.2024)
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Nucleotide-binding oligomerization domain-2 inhibits toll-like receptor-4 signaling in the intestinal epithelium
Richardson, Ward M, Sodhi, Chhinder P, Russo, Anthony, Siggers, Richard H, Afrazi, Amin, Gribar, Steven C, Neal, Matthew D, Dai, Shipan, Prindle, Jr, Thomas, Branca, Maria, Ma, Congrong, Ozolek, John, Hackam, David J
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2010)
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2010)
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Autophagy regulates TLR4 signaling in enterocytes in the pathogenesis of necrotizing enterocolitis
Neal, Matthew D., MD, Sodhi, Chhinder P., PhD, Richardson, Ward M., MD, Russo, Anthony M., BS, Afrazi, Amin, BS, Dai, Shipan, PhD, Hackam, David J., MD, PhD, FACS
Published in Journal of the American College of Surgeons (2010)
Published in Journal of the American College of Surgeons (2010)
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The proinflammatory danger molecule HMGB1 signals via the innate immune receptor TLR4 in the intestinal microvasculature: A novel paradigm in the pathogenesis of NEC
Richardson, Ward M., MD, Afrazi, Amin, BS, Sodhi, Chhinder C., PhD, Russo, Anthony, BS, Branca, Maria F., BS, Prindle, Thomas, BS, Hackam, David J., MD, PhD, FACS
Published in Journal of the American College of Surgeons (2009)
Published in Journal of the American College of Surgeons (2009)
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The NOD2 agonist muramyl-di-peptide (MDP) reverses the inhibitory effects of TLR4 activation on enterocyte proliferation through effects on beta-catenin signaling, and attenuates the severity of experimental necrotizing enterocolitis
Richardson, Ward M., MD, Shi, Xiao-Hua, PhD, Gribar, Steven C., MD, Branca, Maria, BA, Dubowski, Theresa, BA, Li, Jun, Sodhi, Chhindler, PhD, Hackam, David J., MD, PhD, FACS
Published in Journal of the American College of Surgeons (2008)
Published in Journal of the American College of Surgeons (2008)
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Journal Article
78. NOD2 Activation Leads to an Inhibition of TLR4-Mediated Signaling in Enterocytes: A Role for Receptor Cross-Talk in the Pathogenesis of Intestinal Inflammation
Richardson, Ward M, Atsina, Komli-Kofi, Gribar, Steven C, Sodhi, C.P, Li, Jun, Branca, Maria F, Dubowski, Theresa D, Hackam, David J
Published in The Journal of surgical research (2008)
Published in The Journal of surgical research (2008)
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Journal Article
Toll-like receptor 9 (TLR9) activation attenuates TLR4-mediated signaling in enterocytes and reduces the severity of experimental necrotizing enterocolitis
Gribar, Steven C., MD, Richardson, Ward M., MD, Kohler, Jeffrey W., BS, Branca, Maria F., BS, Dubowski, Theresa D., BS, Li, Jun, PhD, Sodhi, Chhinder P., MD, PhD, Hackam, David J., MD, PhD, FACS
Published in Journal of the American College of Surgeons (2008)
Published in Journal of the American College of Surgeons (2008)
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204. The TLR9 Agonist CpG-DNA Protects Against LPS-Induced Enterocyte Apoptosis Through the Up-Regulation of Heat Shock Protein 70 and Reduces the Severity of Necrotizing Enterocolitis in Mice
Gribar, Steven C, Evans, Anna C, Richardson, Ward M, Anand, Rahul J, Kohler, Jeffrey W, Branca, Maria F, Dubowski, Theresa D, Li, Jun, Sodhi, Chhinder P, Hackam, David J
Published in The Journal of surgical research (2008)
Published in The Journal of surgical research (2008)
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Journal Article
A Critical Role for Toll-like Receptor-4 Induction of Autophagy in the Regulation of Enterocyte Migration and the Pathogenesis of Necrotizing Enterocolitis
Neal, Matthew D., Sodhi, Chhinder P., Dyer, Mitchell, Craig, Brian T., Good, Misty, Jia, Hongpeng, Yazji, Ibrahim, Afrazi, Amin, Richardson, Ward M., Beer-Stolz, Donna, Prindle, Thomas, Grant, Zachary, Branca, Maria F., Ozolek, John, Hackam, David J.
Published in The Journal of immunology (1950) (01.03.2013)
Published in The Journal of immunology (1950) (01.03.2013)
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Journal Article