Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis
Richardson, Tom G, Sanderson, Eleanor, Palmer, Tom M, Ala-Korpela, Mika, Ference, Brian A, Davey Smith, George, Holmes, Michael V
Published in PLoS medicine (01.03.2020)
Published in PLoS medicine (01.03.2020)
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Journal Article
Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation
Richardson, Tom G, Leyden, Genevieve M, Wang, Qin, Bell, Joshua A, Elsworth, Benjamin, Davey Smith, George, Holmes, Michael V
Published in PLoS biology (25.02.2022)
Published in PLoS biology (25.02.2022)
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Journal Article
Association between genetically proxied PCSK9 inhibition and prostate cancer risk: A Mendelian randomisation study
Fang, Si, Yarmolinsky, James, Gill, Dipender, Bull, Caroline J, Perks, Claire M, Davey Smith, George, Gaunt, Tom R, Richardson, Tom G
Published in PLoS medicine (03.01.2023)
Published in PLoS medicine (03.01.2023)
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Journal Article
A lifecourse mendelian randomization study highlights the long-term influence of childhood body size on later life heart structure
O'Nunain, Katie, Park, Chloe, Urquijo, Helena, Leyden, Genevieve M, Hughes, Alun D, Davey Smith, George, Richardson, Tom G
Published in PLoS biology (09.06.2022)
Published in PLoS biology (09.06.2022)
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Journal Article
Combined Effect of PNPLA3, TM6SF2, and HSD17B13 Variants on Risk of Cirrhosis and Hepatocellular Carcinoma in the General Population
Gellert‐Kristensen, Helene, Richardson, Tom G., Davey Smith, George, Nordestgaard, Børge G., Tybjærg‐Hansen, Anne, Stender, Stefan
Published in Hepatology (Baltimore, Md.) (01.09.2020)
Published in Hepatology (Baltimore, Md.) (01.09.2020)
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Journal Article
An atlas of polygenic risk score associations to highlight putative causal relationships across the human phenome
Richardson, Tom G, Harrison, Sean, Hemani, Gibran, Davey Smith, George
Published in eLife (05.03.2019)
Published in eLife (05.03.2019)
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Journal Article
Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases
Zheng, Jie, Haberland, Valeriia, Baird, Denis, Walker, Venexia, Haycock, Philip C., Hurle, Mark R., Gutteridge, Alex, Erola, Pau, Liu, Yi, Luo, Shan, Robinson, Jamie, Richardson, Tom G., Staley, James R., Elsworth, Benjamin, Burgess, Stephen, Sun, Benjamin B., Danesh, John, Runz, Heiko, Maranville, Joseph C., Martin, Hannah M., Yarmolinsky, James, Laurin, Charles, Holmes, Michael V., Liu, Jimmy Z., Estrada, Karol, Santos, Rita, McCarthy, Linda, Waterworth, Dawn, Nelson, Matthew R., Smith, George Davey, Butterworth, Adam S., Hemani, Gibran, Scott, Robert A., Gaunt, Tom R.
Published in Nature genetics (01.10.2020)
Published in Nature genetics (01.10.2020)
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Journal Article
Genetic predictors of participation in optional components of UK Biobank
Tyrrell, Jessica, Zheng, Jie, Beaumont, Robin, Hinton, Kathryn, Richardson, Tom G., Wood, Andrew R., Davey Smith, George, Frayling, Timothy M., Tilling, Kate
Published in Nature communications (09.02.2021)
Published in Nature communications (09.02.2021)
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Journal Article
Integrative multiomics analysis highlights immune-cell regulatory mechanisms and shared genetic architecture for 14 immune-associated diseases and cancer outcomes
Prince, Claire, Mitchell, Ruth E., Richardson, Tom G.
Published in American journal of human genetics (02.12.2021)
Published in American journal of human genetics (02.12.2021)
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Journal Article
Characterizing the Causal Pathway for Genetic Variants Associated with Neurological Phenotypes Using Human Brain-Derived Proteome Data
Kibinge, Nelson K., Relton, Caroline L., Gaunt, Tom R., Richardson, Tom G.
Published in American journal of human genetics (04.06.2020)
Published in American journal of human genetics (04.06.2020)
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Journal Article
Separating the genetics of childhood and adult obesity: a validation study of genetic scores for body mass index in adolescence and adulthood in the HUNT Study
Brandkvist, Maria, Bjørngaard, Johan Håkon, Ødegård, Rønnaug Astri, Åsvold, Bjørn Olav, Smith, George Davey, Brumpton, Ben, Hveem, Kristian, Richardson, Tom G, Vie, Gunnhild Åberge
Published in Human molecular genetics (25.02.2021)
Published in Human molecular genetics (25.02.2021)
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Journal Article
Evaluating the direct effects of childhood adiposity on adult systemic metabolism: a multivariable Mendelian randomization analysis
Richardson, Tom G, Mykkänen, Juha, Pahkala, Katja, Ala-Korpela, Mika, Bell, Joshua A, Taylor, Kurt, Viikari, Jorma, Lehtimäki, Terho, Raitakari, Olli, Davey Smith, George
Published in International journal of epidemiology (10.11.2021)
Published in International journal of epidemiology (10.11.2021)
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Journal Article
Life course effects of genetic susceptibility to higher body size on body fat and lean mass: prospective cohort study
Waterfield, Scott, Richardson, Tom G, Davey Smith, George, O’Keeffe, Linda M, Bell, Joshua A
Published in International journal of epidemiology (05.10.2023)
Published in International journal of epidemiology (05.10.2023)
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Journal Article