Assessment of the drug interaction potential and single- and repeat-dose pharmacokinetics of the BRAF inhibitor dabrafenib
Suttle, A Benjamin, Grossmann, Kenneth F, Ouellet, Daniele, Richards-Peterson, Lauren E, Aktan, Gursel, Gordon, Michael S, LoRusso, Patricia M, Infante, Jeffrey R, Sharma, Sunil, Kendra, Kari, Patel, Manish, Pant, Shubham, Arkenau, Hendrik-Tobias, Middleton, Mark R, Blackman, Samuel C, Botbyl, Jeff, Carson, Stanley W
Published in Journal of clinical pharmacology (01.04.2015)
Published in Journal of clinical pharmacology (01.04.2015)
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Concomitant oral and intravenous pharmacokinetics of dabrafenib, a BRAF inhibitor, in patients with BRAF V600 mutation-positive solid tumors
Denton, Cathrine L, Minthorn, Elisabeth, Carson, Stanley W, Young, Graeme C, Richards-Peterson, Lauren E, Botbyl, Jeffrey, Han, Chao, Morrison, Royce A, Blackman, Samuel C, Ouellet, Daniele
Published in Journal of clinical pharmacology (01.09.2013)
Published in Journal of clinical pharmacology (01.09.2013)
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Prediction of the Transporter-Mediated Drug-Drug Interaction Potential of Dabrafenib and Its Major Circulating Metabolites
Ellens, Harma, Johnson, Marta, Lawrence, Sarah K, Watson, Cory, Chen, Liangfu, Richards-Peterson, Lauren E
Published in Drug metabolism and disposition (01.06.2017)
Published in Drug metabolism and disposition (01.06.2017)
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Metabolism and disposition of oral dabrafenib in cancer patients: proposed participation of aryl nitrogen in carbon-carbon bond cleavage via decarboxylation following enzymatic oxidation
Bershas, David A, Ouellet, Daniele, Mamaril-Fishman, Donna B, Nebot, Noelia, Carson, Stanley W, Blackman, Samuel C, Morrison, Royce A, Adams, Jerry L, Jurusik, Kristen E, Knecht, Dana M, Gorycki, Peter D, Richards-Peterson, Lauren E
Published in Drug metabolism and disposition (01.12.2013)
Published in Drug metabolism and disposition (01.12.2013)
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Effect of DPC 333 [(2R)-2-{(3R)-3-amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin -1-yl}-N-hydroxy-4-methylpentanamide], a human tumor necrosis factor α-converting enzyme inhibitor, on the disposition of methotrexate: A transporter-based drug-drug interaction case study
GANG LUO, GARNER, C. Edwin, LEE, Frank W, GAN, Liang-Shang, HAO XIONG, HANBO HU, RICHARDS, Lauren E, BROUWER, Kim L. R, JINGWU DUAN, DECICCO, Carl P, MADUSKUIE, Thomas, SHEN, Helen
Published in Drug metabolism and disposition (01.06.2007)
Published in Drug metabolism and disposition (01.06.2007)
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Elimination Pathways of [14C]Losoxantrone in Four Cancer Patients
JOSHI, Amita S, PIENIASZEK, Henry J, VOKES, Everett E, VOGELZANG, Nicholas J, DAVIDSON, Anna F, RICHARDS, Lauren E, CHAI, Min F, FINIZIO, Michael, RATAIN, Mark J
Published in Drug metabolism and disposition (01.02.2001)
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Published in Drug metabolism and disposition (01.02.2001)
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Mechanism-based inactivation of cytochrome P-450 by heteroatom-substituted cyclopropanes and formation of ring-opened products
Guengerich, F. Peter, Willard, Randolph J, Shea, J. Paul, Richards, Lauren E, Macdonald, Timothy L
Published in Journal of the American Chemical Society (01.10.1984)
Published in Journal of the American Chemical Society (01.10.1984)
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Effect of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide], a Human Tumor Necrosis Factor α-Converting Enzyme Inhibitor, on the Disposition of Methotrexate: A Transporter-Based Drug-Drug Interaction Case Study
Gang Luo, C. Edwin Garner, Hao Xiong, Hanbo Hu, Lauren E. Richards, Kim L. R. Brouwer, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Helen Shen, Frank W. Lee, Liang-Shang Gan
Published in Drug metabolism and disposition (01.06.2007)
Published in Drug metabolism and disposition (01.06.2007)
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Abstract 3773: Absolute bioavailability of BRAF inhibitor GSK2118436: Use of a microtracer study in patients with cancer
Denton, Cathrine L., Carson, Stanley W., Young, Graeme C., Richards-Peterson, Lauren E., Botbyl, Jeffrey, Morrison, Royce A., Blackman, Samuel C., Ouellet, Daniele
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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CANCER TREATMENT METHOD
GUCKERT, MARY, E, RUDO, SHARON, BEHBAHANI, ROYA, RICHARDS, ERIC, M, SWANN, R., SUZANNE, DABROWSKI, CHRISTINE, E, GOODMAN, VICKI, L, CARSON, ROBIN, L, PATEL, KIRAN, A, GILMER, TONA, M, LANE, STEPHEN, R, MARTIN, ANNE-MARIE, SUN, PENG, CORNFELD, MARK, J, OUELLET, DANIELE, HUGHES-EARLE, ANGELA, LEGOS, JEFFREY, J, RICHARDS-PETERSON, LAUREN, E
Year of Publication 04.12.2014
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Year of Publication 04.12.2014
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