Combenefit: an interactive platform for the analysis and visualization of drug combinations
Di Veroli, Giovanni Y, Fornari, Chiara, Wang, Dennis, Mollard, Séverine, Bramhall, Jo L, Richards, Frances M, Jodrell, Duncan I
Published in Bioinformatics (Oxford, England) (15.09.2016)
Published in Bioinformatics (Oxford, England) (15.09.2016)
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Journal Article
CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response
Biasci, Daniele, Smoragiewicz, Martin, Connell, Claire M., Wang, Zhikai, Gao, Ya, Thaventhiran, James E. D., Basu, Bristi, Magiera, Lukasz, Johnson, T. Isaac, Bax, Lisa, Gopinathan, Aarthi, Isherwood, Christopher, Gallagher, Ferdia A., Pawula, Maria, Hudecova, Irena, Gale, Davina, Rosenfeld, Nitzan, Barmpounakis, Petros, Popa, Elizabeta Cristina, Brais, Rebecca, Godfrey, Edmund, Mirk, Fraz, Richards, Frances M., Fearon, Douglas T., Janowitz, Tobias, Jodrell, Duncan I.
Published in Proceedings of the National Academy of Sciences - PNAS (17.11.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (17.11.2020)
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Journal Article
Understanding the Complexity of Porous Graphitic Carbon (PGC) Chromatography: Modulation of Mobile-Stationary Phase Interactions Overcomes Loss of Retention and Reduces Variability
Bapiro, Tashinga E, Richards, Frances M, Jodrell, Duncan I
Published in Analytical chemistry (Washington) (21.06.2016)
Published in Analytical chemistry (Washington) (21.06.2016)
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Journal Article
Anti-tumour effects of a specific anti-ADAM17 antibody in an ovarian cancer model in vivo
Richards, Frances M, Tape, Christopher J, Jodrell, Duncan I, Murphy, Gillian
Published in PloS one (11.07.2012)
Published in PloS one (11.07.2012)
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Journal Article
An automated fitting procedure and software for dose-response curves with multiphasic features
Di Veroli, Giovanni Y, Fornari, Chiara, Goldlust, Ian, Mills, Graham, Koh, Siang Boon, Bramhall, Jo L, Richards, Frances M, Jodrell, Duncan I
Published in Scientific reports (01.10.2015)
Published in Scientific reports (01.10.2015)
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Journal Article
Complete loss of ATM function augments replication catastrophe induced by ATR inhibition and gemcitabine in pancreatic cancer models
Dunlop, Charles R, Wallez, Yann, Johnson, Timothy Isaac, Bernaldo de Quirós Fernández, Sandra, Durant, Stephen T, Cadogan, Elaine B, Lau, Alan, Richards, Frances M, Jodrell, Duncan I
Published in British journal of cancer (27.10.2020)
Published in British journal of cancer (27.10.2020)
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Journal Article
Targeting melanoma's MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors
Sale, Matthew J, Minihane, Emma, Monks, Noel R, Gilley, Rebecca, Richards, Frances M, Schifferli, Kevin P, Andersen, Courtney L, Davies, Emma J, Vicente, Mario Aladren, Ozono, Eiko, Markovets, Aleksandra, Dry, Jonathan R, Drew, Lisa, Flemington, Vikki, Proia, Theresa, Jodrell, Duncan I, Smith, Paul D, Cook, Simon J
Published in Nature communications (14.11.2019)
Published in Nature communications (14.11.2019)
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Journal Article
Development of In Vitro Co-Culture Model in Anti-Cancer Drug Development Cascade
Xu, Ruiling, Richards, Frances M
Published in Combinatorial chemistry & high throughput screening (01.01.2017)
Published in Combinatorial chemistry & high throughput screening (01.01.2017)
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Journal Article
Anti-stromal treatment together with chemotherapy targets multiple signalling pathways in pancreatic adenocarcinoma
Carapuça, Elisabete F, Gemenetzidis, Emilios, Feig, Christine, Bapiro, Tashinga E, Williams, Michael D, Wilson, Abigail S, Delvecchio, Francesca R, Arumugam, Prabhu, Grose, Richard P, Lemoine, Nicholas R, Richards, Frances M, Kocher, Hemant M
Published in The Journal of pathology (01.07.2016)
Published in The Journal of pathology (01.07.2016)
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Journal Article
The ATR Inhibitor AZD6738 Synergizes with Gemcitabine In Vitro and In Vivo to Induce Pancreatic Ductal Adenocarcinoma Regression
Wallez, Yann, Dunlop, Charles R, Johnson, Timothy Isaac, Koh, Siang-Boon, Fornari, Chiara, Yates, James W T, Bernaldo de Quirós Fernández, Sandra, Lau, Alan, Richards, Frances M, Jodrell, Duncan I
Published in Molecular cancer therapeutics (01.08.2018)
Published in Molecular cancer therapeutics (01.08.2018)
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Journal Article
Method To Visualize the Intratumor Distribution and Impact of Gemcitabine in Pancreatic Ductal Adenocarcinoma by Multimodal Imaging
Strittmatter, Nicole, Richards, Frances M, Race, Alan M, Ling, Stephanie, Sutton, Daniel, Nilsson, Anna, Wallez, Yann, Barnes, Jennifer, Maglennon, Gareth, Gopinathan, Aarthi, Brais, Rebecca, Wong, Edmond, Serra, Maria Paola, Atkinson, James, Smith, Aaron, Wilson, Joanne, Hamm, Gregory, Johnson, Timothy I, Dunlop, Charles R, Kaistha, Brajesh P, Bunch, Josephine, Sansom, Owen J, Takats, Zoltan, Andrén, Per E, Lau, Alan, Barry, Simon T, Goodwin, Richard J. A, Jodrell, Duncan I
Published in Analytical chemistry (Washington) (25.01.2022)
Published in Analytical chemistry (Washington) (25.01.2022)
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Journal Article
SPARC independent drug delivery and antitumour effects of nab-paclitaxel in genetically engineered mice
Neesse, Albrecht, Frese, Kristopher K, Chan, Derek S, Bapiro, Tashinga E, Howat, William J, Richards, Frances M, Ellenrieder, Volker, Jodrell, Duncan I, Tuveson, David A
Published in Gut (01.06.2014)
Published in Gut (01.06.2014)
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Journal Article
Mechanistic Distinctions between CHK1 and WEE1 Inhibition Guide the Scheduling of Triple Therapy with Gemcitabine
Koh, Siang-Boon, Wallez, Yann, Dunlop, Charles R, Bernaldo de Quirós Fernández, Sandra, Bapiro, Tashinga E, Richards, Frances M, Jodrell, Duncan I
Published in Cancer research (Chicago, Ill.) (01.06.2018)
Published in Cancer research (Chicago, Ill.) (01.06.2018)
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Journal Article
Suppression of Endothelial Cell FAK Expression Reduces Pancreatic Ductal Adenocarcinoma Metastasis after Gemcitabine Treatment
Roy-Luzarraga, Marina, Reynolds, Louise E, de Luxán-Delgado, Beatriz, Maiques, Oscar, Wisniewski, Laura, Newport, Emma, Rajeeve, Vinothini, Drake, Rebecca J G, Gómez-Escudero, Jesús, Richards, Frances M, Weller, Céline, Dormann, Christof, Meng, Ya-Ming, Vermeulen, Peter B, Saur, Dieter, Sanz-Moreno, Victoria, Wong, Ping-Pui, Géraud, Cyrill, Cutillas, Pedro R, Hodivala-Dilke, Kairbaan
Published in Cancer research (Chicago, Ill.) (16.05.2022)
Published in Cancer research (Chicago, Ill.) (16.05.2022)
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Journal Article
Modelling of the cancer cell cycle as a tool for rational drug development: A systems pharmacology approach to cyclotherapy
Jackson, Robert C, Di Veroli, Giovanni Y, Koh, Siang-Boon, Goldlust, Ian, Richards, Frances M, Jodrell, Duncan I
Published in PLoS computational biology (01.05.2017)
Published in PLoS computational biology (01.05.2017)
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Journal Article
Size-tuneable and immunocompatible polymer nanocarriers for drug delivery in pancreatic cancer
Popov, Andrea Bistrovi, Melle, Francesca, Linnane, Emily, González-López, Cristina, Ahmed, Ishtiaq, Parshad, Badri, Franck, Christoph O, Rahmoune, Hassan, Richards, Frances M, Muñoz-Espín, Daniel, Jodrell, Duncan I, Fairen-Jimenez, David, Fruk, Ljiljana
Published in Nanoscale (05.05.2022)
Published in Nanoscale (05.05.2022)
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Journal Article
Depletion of Macrophages Improves Therapeutic Response to Gemcitabine in Murine Pancreas Cancer
Buchholz, Soeren M, Goetze, Robert G, Singh, Shiv K, Ammer-Herrmenau, Christoph, Richards, Frances M, Jodrell, Duncan I, Buchholz, Malte, Michl, Patrick, Ellenrieder, Volker, Hessmann, Elisabeth, Neesse, Albrecht
Published in Cancers (20.07.2020)
Published in Cancers (20.07.2020)
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Journal Article
T Cell-Mediated Antitumor Immunity Cooperatively Induced By TGFβR1 Antagonism and Gemcitabine Counteracts Reformation of the Stromal Barrier in Pancreatic Cancer
Li, Dandan, Schaub, Nicholas, Guerin, Theresa M, Bapiro, Tashinga E, Richards, Frances M, Chen, Vicky, Talsania, Keyur, Kumar, Parimal, Gilbert, Debra J, Schlomer, Jerome J, Kim, Seong-Jin, Sorber, Rebecca, Teper, Yaroslav, Bautista, Wendy, Palena, Claudia, Ock, Chan-Young, Jodrell, Duncan I, Pate, Nathan, Mehta, Monika, Zhao, Yongmei, Kozlov, Serguei, Rudloff, Udo
Published in Molecular cancer therapeutics (01.10.2021)
Published in Molecular cancer therapeutics (01.10.2021)
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Journal Article