Identification and optimisation of novel sulfonamide, selective vasopressin V₁B receptor antagonists
Baker, James, Bingham, Matilda, Blackburn-Munro, Ruth, Cai, Jiaqiang, Craighead, Mark, Gilfillan, Robert, Goan, Kate, Jaap, David, Milne, Rachel, Richard Morphy, J, Napier, Susan, Presland, Jeremy, Spinks, Gayle, Thomson, Fiona
Published in Bioorganic & medicinal chemistry letters (15.06.2011)
Published in Bioorganic & medicinal chemistry letters (15.06.2011)
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Synthesis and SAR studies of novel 2-(6-aminomethylaryl-2-aryl-4-oxo-quinazolin-3(4H)-yl)acetamide Vasopressin V₁b receptor antagonists
Napier, Susan E, Letourneau, Jeffrey J, Ansari, Nasrin, Auld, Douglas S, Baker, James, Best, Stuart, Campbell-Wan, Leigh, Chan, Ray, Craighead, Mark, Desai, Hema, Ho, Koc-Kan, MacSweeney, Cliona, Milne, Rachel, Richard Morphy, J, Neagu, Irina, Ohlmeyer, Michael H.J, Pick, Jack, Presland, Jeremy, Riviello, Chris, Zanetakos, Heather A, Zhao, Jiuqiao, Webb, Maria L
Published in Bioorganic & medicinal chemistry letters (15.06.2011)
Published in Bioorganic & medicinal chemistry letters (15.06.2011)
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Synthesis and SAR studies of novel 2-(6-aminomethylaryl-2-aryl-4-oxo-quinazolin-3(4 H)-yl)acetamide Vasopressin V 1b receptor antagonists
Napier, Susan E., Letourneau, Jeffrey J., Ansari, Nasrin, Auld, Douglas S., Baker, James, Best, Stuart, Campbell-Wan, Leigh, Chan, Ray, Craighead, Mark, Desai, Hema, Ho, Koc-Kan, MacSweeney, Cliona, Milne, Rachel, Richard Morphy, J., Neagu, Irina, Ohlmeyer, Michael H.J., Pick, Jack, Presland, Jeremy, Riviello, Chris, Zanetakos, Heather A., Zhao, Jiuqiao, Webb, Maria L.
Published in Bioorganic & medicinal chemistry letters (15.06.2011)
Published in Bioorganic & medicinal chemistry letters (15.06.2011)
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Journal Article
Identification and optimisation of novel sulfonamide, selective vasopressin V 1B receptor antagonists
Baker, James, Bingham, Matilda, Blackburn-Munro, Ruth, Cai, Jiaqiang, Craighead, Mark, Gilfillan, Robert, Goan, Kate, Jaap, David, Milne, Rachel, Richard Morphy, J., Napier, Susan, Presland, Jeremy, Spinks, Gayle, Thomson, Fiona
Published in Bioorganic & medicinal chemistry letters (15.06.2011)
Published in Bioorganic & medicinal chemistry letters (15.06.2011)
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Discovery and optimisation of a selective non-steroidal glucocorticoid receptor antagonist
Brown, Angus R., Bosies, Michael, Cameron, Helen, Clark, John, Cowley, Angela, Craighead, Mark, Elmore, Moira A., Firth, Alistair, Goodwin, Richard, Goutcher, Susan, Grant, Emma, Grassie, Morag, Grove, Simon J.A., Hamilton, Niall M., Hampson, Hannah, Hillier, Alison, Ho, Koc-Kan, Kiczun, Michael, Kingsbury, Celia, Kultgen, Steven G., Littlewood, Peter T.A., Lusher, Scott J., MacDonald, Susan, McIntosh, Lorraine, McIntyre, Theresa, Mistry, Ashvin, Morphy, J. Richard, Nimz, Olaf, Ohlmeyer, Michael, Pick, Jack, Rankovic, Zoran, Sherborne, Brad, Smith, Alasdair, Speake, Michael, Spinks, Gayle, Thomson, Fiona, Watson, Lynn, Weston, Mark
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
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Journal Article
Synthesis and SAR studies of novel 2-(4-oxo-2-aryl-quinazolin-3(4H)-yl)acetamide vasopressin V₁b receptor antagonists
Napier, Susan E, Letourneau, Jeffrey J, Ansari, Nasrin, Auld, Douglas S, Baker, James, Best, Stuart, Campbell-Wan, Leigh, Chan, Jui-Hsiang, Craighead, Mark, Desai, Hema, Goan, Katharine A, Ho, Koc-Kan, Hulskotte, Ellen G.J, MacSweeney, Cliona P, Milne, Rachel, Morphy, J. Richard, Neagu, Irina, Ohlmeyer, Michael H.J, Peeters, Ard W.M.M, Presland, Jeremy, Riviello, Chris, Ruigt, Ge S.F, Thomson, Fiona J, Zanetakos, Heather A, Zhao, Jiuqiao, Webb, Maria L
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
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Identification and optimization of novel 2-(4-oxo-2-aryl-quinazolin-3(4 H)-yl)acetamide vasopressin V3 (V1b) receptor antagonists
Letourneau, Jeffrey J., Riviello, Christopher M., Li, Hong, Cole, Andrew G., Ho, Koc-Kan, Zanetakos, Heather A., Desai, Hema, Zhao, Jiuqiao, Auld, Douglas S., Napier, Susan E., Thomson, Fiona J., Goan, Katharine A., Morphy, J. Richard, Ohlmeyer, Michael H.J., Webb, Maria L.
Published in Bioorganic & medicinal chemistry letters (15.09.2010)
Published in Bioorganic & medicinal chemistry letters (15.09.2010)
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Synthesis of Tertiary Amines Using a Polystyrene (REM) Resin
Brown, Angus R, Rees, David C, Rankovic, Zoran, Morphy, J. Richard
Published in Journal of the American Chemical Society (09.04.1997)
Published in Journal of the American Chemical Society (09.04.1997)
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The First Potent and Selective Inhibitors of the Glycine Transporter Type 2
Caulfield, Wilson L, Collie, Iain T, Dickins, Rachel S, Epemolu, Ola, McGuire, Ross, Hill, David R, McVey, Gillian, Morphy, J. Richard, Rankovic, Zoran, Sundaram, Hardy
Published in Journal of medicinal chemistry (16.08.2001)
Published in Journal of medicinal chemistry (16.08.2001)
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2-(Aminomethyl)-benzamide-based glycine transporter type-2 inhibitors
Ho, Koc-Kan, Appell, Kenneth C., Baldwin, John J., Bohnstedt, Adolph C., Dong, Guizhen, Guo, Tao, Horlick, Robert, Islam, Khondaker R., Kultgen, Steven G., Masterson, Christopher M., McDonald, Edward, McMillan, Kirk, Morphy, J.Richard, Rankovic, Zoran, Sundaram, Hardy, Webb, Maria
Published in Bioorganic & medicinal chemistry letters (19.01.2004)
Published in Bioorganic & medicinal chemistry letters (19.01.2004)
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Synthesis and SAR studies of 3-phenoxypropyl piperidine analogues as ORL1 (NOP) receptor agonists
Palin, Ronald, Barn, David R., Clark, John K., Cottney, Jean E., Cowley, Phillip M., Crockatt, Marc, Evans, Louise, Feilden, Helen, Goodwin, Richard R., Griekspoor, Frank, Grove, Simon J.A., Houghton, Andrea K., Jones, Philip S., Morphy, Richard J., Smith, Alasdair R.C., Sundaram, Hardy, Vrolijk, David, Weston, Mark A., Wishart, Grant, Wren, Paul
Published in Bioorganic & medicinal chemistry letters (01.02.2005)
Published in Bioorganic & medicinal chemistry letters (01.02.2005)
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Journal Article
Synthesis and SAR studies of novel 2-(4-oxo-2-aryl-quinazolin-3(4 H)-yl)acetamide vasopressin V 1b receptor antagonists
Napier, Susan E., Letourneau, Jeffrey J., Ansari, Nasrin, Auld, Douglas S., Baker, James, Best, Stuart, Campbell-Wan, Leigh, Chan, Jui-Hsiang, Craighead, Mark, Desai, Hema, Goan, Katharine A., Ho, Koc-Kan, Hulskotte, Ellen G.J., MacSweeney, Cliona P., Milne, Rachel, Morphy, J. Richard, Neagu, Irina, Ohlmeyer, Michael H.J., Peeters, Ard W.M.M., Presland, Jeremy, Riviello, Chris, Ruigt, Ge S.F., Thomson, Fiona J., Zanetakos, Heather A., Zhao, Jiuqiao, Webb, Maria L.
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
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Optimization of Reaction Conditions for REM Resin-Bound Quaternization Reactions
Cameron, Kenneth S, Morphy, J. Richard, Rankovic, Zoran, York, Mark
Published in Journal of combinatorial chemistry (01.05.2002)
Published in Journal of combinatorial chemistry (01.05.2002)
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