Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders
Yang, Chengran, Farias, Fabiana H. G., Ibanez, Laura, Suhy, Adam, Sadler, Brooke, Fernandez, Maria Victoria, Wang, Fengxian, Bradley, Joseph L., Eiffert, Brett, Bahena, Jorge A., Budde, John P., Li, Zeran, Dube, Umber, Sung, Yun Ju, Mihindukulasuriya, Kathie A., Morris, John C., Fagan, Anne M., Perrin, Richard J., Benitez, Bruno A., Rhinn, Herve, Harari, Oscar, Cruchaga, Carlos
Published in Nature neuroscience (01.09.2021)
Published in Nature neuroscience (01.09.2021)
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A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain
Del-Aguila, Jorge L, Li, Zeran, Dube, Umber, Mihindukulasuriya, Kathie A, Budde, John P, Fernandez, Maria Victoria, Ibanez, Laura, Bradley, Joseph, Wang, Fengxian, Bergmann, Kristy, Davenport, Richard, Morris, John C, Holtzman, David M, Perrin, Richard J, Benitez, Bruno A, Dougherty, Joseph, Cruchaga, Carlos, Harari, Oscar
Published in Alzheimer's research & therapy (09.08.2019)
Published in Alzheimer's research & therapy (09.08.2019)
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Increasing participant diversity in AD research: Plans for digital screening, blood testing, and a community‐engaged approach in the Alzheimer's Disease Neuroimaging Initiative 4
Weiner, Michael W., Veitch, Dallas P., Miller, Melanie J., Aisen, Paul S., Albala, Bruce, Beckett, Laurel A., Green, Robert C., Harvey, Danielle, Jack, Clifford R., Jagust, William, Landau, Susan M., Morris, John C., Nosheny, Rachel, Okonkwo, Ozioma C., Perrin, Richard J., Petersen, Ronald C., Rivera‐Mindt, Monica, Saykin, Andrew J., Shaw, Leslie M, Toga, Arthur W., Tosun, Duygu, Trojanowski, John Q.
Published in Alzheimer's & dementia (01.01.2023)
Published in Alzheimer's & dementia (01.01.2023)
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Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers
Brase, Logan, You, Shih-Feng, D’Oliveira Albanus, Ricardo, Del-Aguila, Jorge L., Dai, Yaoyi, Novotny, Brenna C., Soriano-Tarraga, Carolina, Dykstra, Taitea, Fernandez, Maria Victoria, Budde, John P., Bergmann, Kristy, Morris, John C., Bateman, Randall J., Perrin, Richard J., McDade, Eric, Xiong, Chengjie, Goate, Alison M., Farlow, Martin, Sutherland, Greg T., Kipnis, Jonathan, Karch, Celeste M., Benitez, Bruno A., Harari, Oscar
Published in Nature communications (21.04.2023)
Published in Nature communications (21.04.2023)
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Mendelian randomization and genetic colocalization infer the effects of the multi-tissue proteome on 211 complex disease-related phenotypes
Yang, Chengran, Fagan, Anne M, Perrin, Richard J, Rhinn, Herve, Harari, Oscar, Cruchaga, Carlos
Published in Genome medicine (12.12.2022)
Published in Genome medicine (12.12.2022)
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Accelerated longitudinal changes and ordering of Alzheimer disease biomarkers across the adult lifespan
Luo, Jingqin, Agboola, Folasade, Grant, Elizabeth, Morris, John C, Masters, Colin L, Albert, Marilyn S, Johnson, Sterling C, McDade, Eric M, Fagan, Anne M, Benzinger, Tammie L S, Hassenstab, Jason, Bateman, Randall J, Perrin, Richard J, Wang, Guoqiao, Li, Yan, Gordon, Brian, Cruchaga, Carlos, Day, Gregory S, Levin, Johannes, Vöglein, Jonathan, Ikeuchi, Takeshi, Suzuki, Kazushi, Allegri, Ricardo F, Xiong, Chengjie
Published in Brain (London, England : 1878) (19.12.2022)
Published in Brain (London, England : 1878) (19.12.2022)
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Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue
Dhavale, Dhruva D., Barclay, Alexander M., Borcik, Collin G., Basore, Katherine, Berthold, Deborah A., Gordon, Isabelle R., Liu, Jialu, Milchberg, Moses H., O’Shea, Jennifer Y., Rau, Michael J., Smith, Zachary, Sen, Soumyo, Summers, Brock, Smith, John, Warmuth, Owen A., Perrin, Richard J., Perlmutter, Joel S., Chen, Qian, Fitzpatrick, James A. J., Schwieters, Charles D., Tajkhorshid, Emad, Rienstra, Chad M., Kotzbauer, Paul T.
Published in Nature communications (29.03.2024)
Published in Nature communications (29.03.2024)
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Multiplexed immunoassay panel identifies novel CSF biomarkers for Alzheimer's disease diagnosis and prognosis
Craig-Schapiro, Rebecca, Kuhn, Max, Xiong, Chengjie, Pickering, Eve H, Liu, Jingxia, Misko, Thomas P, Perrin, Richard J, Bales, Kelly R, Soares, Holly, Fagan, Anne M, Holtzman, David M
Published in PloS one (19.04.2011)
Published in PloS one (19.04.2011)
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TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers
Del-Aguila, Jorge L, Benitez, Bruno A, Li, Zeran, Dube, Umber, Mihindukulasuriya, Kathie A, Budde, John P, Farias, Fabiana H G, Fernández, Maria Victoria, Ibanez, Laura, Jiang, Shan, Perrin, Richard J, Cairns, Nigel J, Morris, John C, Harari, Oscar, Cruchaga, Carlos
Published in Molecular neurodegeneration (08.05.2019)
Published in Molecular neurodegeneration (08.05.2019)
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Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer's disease
Eteleeb, Abdallah M, Novotny, Brenna C, Tarraga, Carolina Soriano, Sohn, Christopher, Dhungel, Eliza, Brase, Logan, Nallapu, Aasritha, Buss, Jared, Farias, Fabiana, Bergmann, Kristy, Bradley, Joseph, Norton, Joanne, Gentsch, Jen, Wang, Fengxian, Davis, Albert A, Morris, John C, Karch, Celeste M, Perrin, Richard J, Benitez, Bruno A, Harari, Oscar
Published in PLoS biology (30.04.2024)
Published in PLoS biology (30.04.2024)
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Multimodal brain age estimates relate to Alzheimer disease biomarkers and cognition in early stages: a cross-sectional observational study
Millar, Peter R, Gordon, Brian A, Luckett, Patrick H, Benzinger, Tammie L S, Cruchaga, Carlos, Fagan, Anne M, Hassenstab, Jason J, Perrin, Richard J, Schindler, Suzanne E, Allegri, Ricardo F, Day, Gregory S, Farlow, Martin R, Mori, Hiroshi, Nübling, Georg, Bateman, Randall J, Morris, John C, Ances, Beau M
Published in eLife (06.01.2023)
Published in eLife (06.01.2023)
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Covariance-based vs. correlation-based functional connectivity dissociates healthy aging from Alzheimer disease
Strain, Jeremy F., Brier, Matthew R., Tanenbaum, Aaron, Gordon, Brian A., McCarthy, John E., Dincer, Aylin, Marcus, Daniel S., Chhatwal, Jasmeer P., Graff-Radford, Neill R., Day, Gregory S., la Fougère, Christian, Perrin, Richard J., Salloway, Stephen, Schofield, Peter R., Yakushev, Igor, Ikeuchi, Takeshi, Vöglein, Jonathan, Morris, John C., Benzinger, Tammie L.S., Bateman, Randall J., Ances, Beau M., Snyder, Abraham Z.
Published in NeuroImage (Orlando, Fla.) (01.11.2022)
Published in NeuroImage (Orlando, Fla.) (01.11.2022)
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Regional correlation of biochemical measures of amyloid and tau phosphorylation in the brain
Horie, Kanta, Barthélemy, Nicolas R, Mallipeddi, Nipun, Li, Yan, Franklin, Erin E, Perrin, Richard J, Bateman, Randall J, Sato, Chihiro
Published in Acta neuropathologica communications (27.08.2020)
Published in Acta neuropathologica communications (27.08.2020)
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Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer's disease
Wang, Lihua, Nykänen, Niko-Petteri, Western, Daniel, Gorijala, Priyanka, Timsina, Jigyasha, Li, Fuhai, Wang, Zhaohua, Ali, Muhammad, Yang, Chengran, Liu, Menghan, Brock, William, Marquié, Marta, Boada, Mercè, Alvarez, Ignacio, Aguilar, Miquel, Pastor, Pau, Ruiz, Agustín, Puerta, Raquel, Orellana, Adelina, Rutledge, Jarod, Oh, Hamilton, Greicius, Michael D, Le Guen, Yann, Perrin, Richard J, Wyss-Coray, Tony, Jefferson, Angela, Hohman, Timothy J, Graff-Radford, Neill, Mori, Hiroshi, Goate, Alison, Levin, Johannes, Sung, Yun Ju, Cruchaga, Carlos
Published in Molecular neurodegeneration (03.01.2024)
Published in Molecular neurodegeneration (03.01.2024)
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Detection of neoantigen-specific T cells following a personalized vaccine in a patient with glioblastoma
Johanns, Tanner M, Miller, Christopher A, Liu, Connor J, Perrin, Richard J, Bender, Diane, Kobayashi, Dale K, Campian, Jian L, Chicoine, Michael R, Dacey, Ralph G, Huang, Jiayi, Fritsch, Edward F, Gillanders, William E, Artyomov, Maxim N, Mardis, Elaine R, Schreiber, Robert D, Dunn, Gavin P
Published in Oncoimmunology (01.01.2019)
Published in Oncoimmunology (01.01.2019)
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Identification and validation of novel cerebrospinal fluid biomarkers for staging early Alzheimer's disease
Perrin, Richard J, Craig-Schapiro, Rebecca, Malone, James P, Shah, Aarti R, Gilmore, Petra, Davis, Alan E, Roe, Catherine M, Peskind, Elaine R, Li, Ge, Galasko, Douglas R, Clark, Christopher M, Quinn, Joseph F, Kaye, Jeffrey A, Morris, John C, Holtzman, David M, Townsend, R Reid, Fagan, Anne M
Published in PloS one (12.01.2011)
Published in PloS one (12.01.2011)
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Brain collection, standardized neuropathologic assessment, and comorbidity in Alzheimer's Disease Neuroimaging Initiative 2 participants
Franklin, Erin E, Perrin, Richard J, Vincent, Benjamin, Baxter, Michael, Morris, John C, Cairns, Nigel J
Published in Alzheimer's & dementia (01.07.2015)
Published in Alzheimer's & dementia (01.07.2015)
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Neuroinflammation and Myelin Status in Alzheimer’s Disease, Parkinson’s Disease, and Normal Aging Brains: A Small Sample Study
Xu, Jinbin, Morris, John C., Perlmutter, Joel S., Wang, Yong, Wang, Qing, Perrin, Richard J., Han, Fei, Benzinger, Tammie L. S.
Published in Parkinson's disease (2019)
Published in Parkinson's disease (2019)
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Neuropathologic assessment of participants in two multi-center longitudinal observational studies: The Alzheimer Disease Neuroimaging Initiative (ADNI) and the Dominantly Inherited Alzheimer Network (DIAN)
Cairns, Nigel J., Perrin, Richard J., Franklin, Erin E., Carter, Deborah, Vincent, Benjamin, Xie, Mingqiang, Bateman, Randall J., Benzinger, Tammie, Friedrichsen, Karl, Brooks, William S., Halliday, Glenda M., McLean, Catriona, Ghetti, Bernardino, Morris, John C.
Published in Neuropathology (01.08.2015)
Published in Neuropathology (01.08.2015)
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