Assessing Variant-Dependent Heterogeneity in β-Amyloid Burden in Autosomal Dominant Alzheimer’s Disease: a cross-sectional and longitudinal study
Chhatwal, Jasmeer P, Schultz, Stephanie A, McDade, Eric, Schultz, Aaron P, Liu, Lei, Hanseeuw, Bernard J, Joseph-Mathurin, Nelly, Feldman, Rebecca, Fitzpatrick, Colleen D, Sparks, Kathryn P, Levin, Johannes, Berman, Sarah B, Renton, Alan E, Esposito, Bianca T, Vitoria Fernandez, Maria, Ju Sung, Yun, Hong Lee, Jae, Klunk, William E, Hofmann, Anna, Noble, James M, Graff-Radford, Neill, Mori, Hiroshi, Salloway, Steven M, Masters, Colin L, Martins, Ralph, Karch, Celeste M, Xiong, Chengjie, Cruchaga, Carlos, Perrin, Richard J, Gordon, Brian A, Benzinger, Tammie LS, Fox, Nick C, Schofield, Peter R, Fagan, Anne M, Goate, Alison M, Morris, John C, Bateman, Randall J, Johnson, Keith A, Sperling, Reisa A
Published in Lancet neurology (01.02.2022)
Published in Lancet neurology (01.02.2022)
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Longitudinal head-to-head comparison of 11C-PiB and 18F-florbetapir PET in a Phase 2/3 clinical trial of anti-amyloid-β monoclonal antibodies in dominantly inherited Alzheimer disease
Chen, Charles D., McCullough, Austin, Gordon, Brian, Joseph-Mathurin, Nelly, Flores, Shaney, McKay, Nicole S., Hobbs, Diana A., Hornbeck, Russ, Fagan, Anne M., Cruchaga, Carlos, Goate, Alison M., Perrin, Richard J., Wang, Guoqiao, Li, Yan, Shi, Xinyu, Xiong, Chengjie, Pontecorvo, Michael J., Klein, Gregory, Su, Yi, Klunk, William E., Jack, Clifford, Koeppe, Robert, Snider, B. Joy, Berman, Sarah B., Roberson, Erik D., Brosch, Jared, Surti, Ghulam, Jiménez-Velázquez, Ivonne Z., Galasko, Douglas, Honig, Lawrence S., Brooks, William S., Clarnette, Roger, Wallon, David, Dubois, Bruno, Pariente, Jérémie, Pasquier, Florence, Sanchez-Valle, Raquel, Shcherbinin, Sergey, Higgins, Ixavier, Tunali, Ilke, Masters, Colin L., van Dyck, Christopher H., Masellis, Mario, Hsiung, Robin, Gauthier, Serge, Salloway, Steve, Clifford, David B., Mills, Susan, Supnet-Bell, Charlene, McDade, Eric, Bateman, Randall J., Benzinger, Tammie L.S.
Published in European journal of nuclear medicine and molecular imaging (05.04.2023)
Published in European journal of nuclear medicine and molecular imaging (05.04.2023)
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IC‐P‐046: CEREBRAL AMYLOID ANGIOPATHY IS MORE SEVERE IN AUTOSOMAL DOMINANT AD CASES WITH CEREBRAL MICROHEMORRHAGES: RESULTS FROM THE DIAN STUDY
Joseph-Mathurin, Nelly, Perrin, Richard J., Cairns, Nigel J., Franklin, Erin E., Xiong, Chengjie, Preboske, Gregory M., Jack, Clifford R., Morris, John C., Bateman, Randall, Benzinger, Tammie L.S.
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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Journal Article
CEREBRAL AMYLOID ANGIOPATHY IS MORE SEVERE IN AUTOSOMAL DOMINANT AD CASES WITH CEREBRAL MICROHEMORRHAGES: RESULTS FROM THE DIAN STUDY
Joseph-Mathurin, Nelly, Perrin, Richard J., Cairns, Nigel J., Franklin, Erin E., Xiong, Chengjie, Preboske, Gregory M., Jack, Clifford R., Morris, John C., Bateman, Randall, Benzinger, Tammie L.S.
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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P2‐253: ANTEMORTEM CSF α‐SYNUCLEIN PREDICTS TIME UNTIL DEATH IN AN AUTOPSY COHORT
Henson, Rachel L., Amtashar, Fatima S., Schindler, Suzanne E., Perrin, Richard J., Vanderstichele, Hugo Marcel, Venkataraman, Iswariya, Morris, John C., Fagan, Anne M.
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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Journal Article
ANTEMORTEM CSF α-SYNUCLEIN PREDICTS TIME UNTIL DEATH IN AN AUTOPSY COHORT
Henson, Rachel L., Amtashar, Fatima S., Schindler, Suzanne E., Perrin, Richard J., Vanderstichele, Hugo Marcel, Venkataraman, Iswariya, Morris, John C., Fagan, Anne M.
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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Journal Article
CEREBRAL AMYLOID ANGIOPATHY IS MORE SEVERE IN AUTOSOMAL DOMINANT AD CASES WITH CEREBRAL MICROHEMORRHAGES: RESULTS FROM THE DIAN STUDY
Joseph-Mathurin, Nelly, Perrin, Richard J., Cairns, Nigel J., Franklin, Erin E., Xiong, Chengjie, Preboske, Gregory M., Jack, Clifford R., Morris, John C., Bateman, Randall, Benzinger, Tammie L.S.
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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Journal Article
P3‐432: CEREBRAL AMYLOID ANGIOPATHY IS MORE SEVERE IN AUTOSOMAL DOMINANT AD CASES WITH CEREBRAL MICROHEMORRHAGES: RESULTS FROM THE DIAN STUDY
Joseph-Mathurin, Nelly, Perrin, Richard J., Cairns, Nigel J., Franklin, Erin E., Xiong, Chengjie, Preboske, Gregory M., Jack, Clifford R., Morris, John C., Bateman, Randall, Benzinger, Tammie L.S.
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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Journal Article
Longitudinal cascades of Alzheimer disease biomarkers across the entire adult lifespan among cognitively normal adults
Xiong, Chengjie, Luo, Jingqin, Agboola, Folasade, Grant, Elizabeth A., Masters, Colin L., Albert, Marilyn S., Johnson, Sterling C., McDade, Eric, Fagan, Anne M., Benzinger, Tammie L.S., Hassenstab, Jason, Bateman, Randall J., Moulder, Krista L., Perrin, Richard J., Cruchaga, Carlos, Morris, John C.
Published in Alzheimer's & dementia (01.12.2021)
Published in Alzheimer's & dementia (01.12.2021)
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Journal Article
Imaging measures of molecular pathology and neurodegeneration in dominantly‐inherited and sporadic early‐onset Alzheimer’s Disease
Iaccarino, Leonardo, Llibre‐Guerra, Jorge J., Edwards, Lauren, Mundada, Nidhi, Strom, Amelia, Tsoy, Elena, Li, Yan, Gordon, Brian A., Schindler, Suzanne E., Fagan, Anne M., Benzinger, Tammie L.S., Wang, Guoqiao, Hassenstab, Jason, Morris, John C., Xiong, Chengjie, Perrin, Richard J., Soleimani‐Meigooni, David N., Miller, Zachary A., Kramer, Joel H., Rosen, Howard J., La Joie, Renaud, Miller, Bruce L., Bateman, Randall J., Rabinovici, Gil D.
Published in Alzheimer's & dementia (01.12.2021)
Published in Alzheimer's & dementia (01.12.2021)
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α‐Synuclein seed amplification assay detects Lewy body co‐pathology in autosomal dominant Alzheimer's disease late in the disease course and dependent on Lewy pathology burden
Levin, Johannes, Baiardi, Simone, Quadalti, Corinne, Rossi, Marcello, Mammana, Angela, Vöglein, Jonathan, Bernhardt, Alexander, Perrin, Richard J., Jucker, Mathias, Preische, Oliver, Hofmann, Anna, Höglinger, Günter U., Cairns, Nigel J., Franklin, Erin E., Chrem, Patricio, Cruchaga, Carlos, Berman, Sarah B., Chhatwal, Jasmeer P., Daniels, Alisha, Day, Gregory S., Ryan, Natalie S., Goate, Alison M., Gordon, Brian A., Huey, Edward D., Ibanez, Laura, Karch, Celeste M., Lee, Jae‐Hong, Llibre‐Guerra, Jorge, Lopera, Francisco, Masters, Colin L., Morris, John C., Noble, James M., Renton, Alan E., Roh, Jee Hoon, Frosch, Matthew P., Keene, C. Dirk, McLean, Catriona, Sanchez‐Valle, Raquel, Schofield, Peter R., Supnet‐Bell, Charlene, Xiong, Chengjie, Giese, Armin, Hansson, Oskar, Bateman, Randall J., McDade, Eric, Parchi, Piero
Published in Alzheimer's & dementia (01.06.2024)
Published in Alzheimer's & dementia (01.06.2024)
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Journal Article
Cross‐sectional comparison of the role of tau burden among Down Syndrome Alzheimer disease and autosomal‐dominant Alzheimer disease
Wisch, Julie K., Gordon, Brian A., Boerwinkle, Anna H., Flores, Shaney, McKay, Nicole S., Henson, Rachel L., Thippabhotla, Sharmila, Kennedy, James Tyler, Butt, Omar Hameed, Chen, Charles D., Handen, Benjamin L., Christian, Bradley T., Head, Elizabeth, Mapstone, Mark, Tudorascu, Dana, Zammit, Matthew D, Cohen, Annie, Johnson, Sterling C, Fagan, Anne M., Klunk, William E, Rafii, Michael S, O'Bryant, Sid E., Price, Julie C, Schupf, Nicole, Laymon, Charles M, Yassa, Michael A., Keator, David B., Krinsky‐McHale, Sharon J, Lai, Florence, Rosas, H. Diana, Hartley, Sigan, Zaman, Shahid, Lott, Ira T, Silverman, Wayne, Lao, Patrick J., Brickman, Adam M., Lee, Joseph H., Allegri, Ricardo Francisco, Berman, Sarah, Chhatwal, Jasmeer P., Chui, Helena C, Cruchaga, Carlos, Farlow, Martin R., Fox, Nick C, Goate, Alison, Day, Gregory S., Graff‐Radford, Neill R, Jucker, Mathias, Lee, Jae‐Hong, Levin, Johannes, Martins, Ralph N, Mori, Hiroshi, Perrin, Richard J., Salloway, Stephen, Sanchez‐Valle, Raquel, Schofield, Peter W., Xiong, Chengjie, Schindler, Suzanne E., Morris, John C, Karch, Celeste M., Hassenstab, Jason J., Benzinger, Tammie L.S., McDade, Eric, Bateman, Randall J., Ances, Beau
Published in Alzheimer's & dementia (01.12.2023)
Published in Alzheimer's & dementia (01.12.2023)
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Journal Article
Changes in cortical thickness along the Alzheimer disease continuum in people with Down syndrome
Kennedy, James Tyler, Dincer, Aylin, Thippabhotla, Sharmila, Roman, June, Wisch, Julie K., Gordon, Brian A., Boerwinkle, Anna H., Flores, Shaney, Chen, Charles D., Benzinger, Tammie L.S., Klunk, William E, Rafii, Michael S, O'Bryant, Sid E., Price, Julie C, Yassa, Michael A., Sathishkumar, Mithra, McMillan, Liv, Brickman, Adam M., Lao, Patrick J., Laymon, Charles M, Krinsky‐McHale, Sharon J, Lai, Florence, Rosas, H. Diana, Hartley, Sigan, Zaman, Shahid, Lott, Ira T, Silverman, Wayne, Lee, Joseph H., Allegri, Ricardo Francisco, Berman, Sarah, Chhatwal, Jasmeer P., Chui, Helena C, Cruchaga, Carlos, Farlow, Martin R., Goate, Alison, Day, Gregory S., Graff‐Radford, Neill R, Jucker, Mathias, Lee, Jae‐Hong, Levin, Johannes, Martins, Ralph N, Mori, Hiroshi, Perrin, Richard J., Salloway, Stephen, Sanchez‐Valle, Raquel, Xiong, Chengjie, Karch, Celeste M., Hassenstab, Jason J., McDade, Eric, Bateman, Randall J., Handen, Benjamin L., Head, Elizabeth, Mapstone, Mark, Christian, Bradley T., Ances, Beau, Schofield, Peter R, Network, Dominantly Inherited Alzheimer
Published in Alzheimer's & dementia (01.12.2023)
Published in Alzheimer's & dementia (01.12.2023)
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Journal Article
Refinement of Neurofilament light Dynamics in CSF and Blood for familial Alzheimer’s Disease
Hofmann, Anna, Haesler, Lisa M., Preische, Oliver, Gräber‐Sultan, Susanne, Obermüller, Ulrike, Vöglein, Jonathan, Levin, Johannes, Laske, Christoph, Fitzpatrick, Colleen D, Levin, Raina, Joseph‐Mathurin, Nelly, Chen, Charles D., Cruchaga, Carlos, Goate, Alison, Allegri, Ricardo Francisco, Benzinger, Tammie L.S., Berman, Sarah, Chui, Helena C, Fagan, Anne M., Farlow, Martin R., Fox, Nick C, Day, Gregory S., Hassenstab, Jason J., Jack, Clifford R., Lee, Jae‐Hong, Levey, Allan I., Martins, Ralph N, Mori, Hiroshi, Noble, James M, Perrin, Richard J., Sperling, Reisa A., Rosa‐Neto, Pedro, Salloway, Stephen, Sanchez‐Valle, Raquel, Schofield, Peter R, Xiong, Chengjie, Karch, Celeste M., Graff‐Radford, Neill R, Gordon, Brian A., Morris, John C, McDade, Eric, Bateman, Randall J., Chhatwal, Jasmeer P., Jucker, Mathias, Schultz, Stephanie A.
Published in Alzheimer's & dementia (01.12.2023)
Published in Alzheimer's & dementia (01.12.2023)
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Journal Article
Plasma glial fibrillary acidic protein in autosomal dominant Alzheimer’s disease: associations with β-amyloid-PET, neurodegeneration and cognition
Chatterjee, Pratishtha, Vermunt, Lisa, Gordon, Brian A., Pedrini, Steve, Boonkamp, Lynn, Armstrong, Nicola J., Xiong, Chengjie, Singh, Abhay K., Li, Yan, Sohrabi, Hamid R., Taddei, Kevin, Molloy, Mark P., Benzinger, Tammie L.S., Morris, John C., Karch, Celeste M., Berman, Sarah B., Chhatwal, Jasmeer, Cruchaga, Carlos, Graff-Radford, Neill R., Day, Gregory S, Farlow, Martin, Fox, Nick C., Goate, Alison M., Hassenstab, Jason, Lee, Jae-Hong, Levin, Johannes, McDade, Eric, Mori, Hiroshi, Perrin, Richard J., Sanchez-Valle, Raquel, Schofield, Peter R., Levey, Allan, Jucker, Mathias, Masters, Colin L., Fagan, Anne M., Bateman, Randall J., Martins, Ralph N., Teunissen, Charlotte E.
Published in Alzheimer's & dementia (28.12.2022)
Published in Alzheimer's & dementia (28.12.2022)
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Journal Article
Clinical, cognitive and biomarker profiles in dominantly‐inherited versus sporadic early‐onset Alzheimer’s disease
Llibre‐Guerra, Jorge J, Iaccarino, Leonardo, Li, Yan, Edwards, Lauren, McDade, Eric, Strom, Amelia, Gordon, Brian A., Mundada, Nidhi, Schindler, Suzanne E., Tsoy, Elena, Fagan, Anne M, La Joie, Renaud, Benzinger, Tammie L.S., Soleimani‐Meigooni, David N., Aschenbrenner, Andrew J., Miller, Zachary A., Wang, Guoqiao, Kramer, Joel H, Hassenstab, Jason, Rosen, Howard J., Morris, John C., Miller, Bruce L., Xiong, Chengjie, Perrin, Richard J., Rabinovici, Gil D., Bateman, Randall J.
Published in Alzheimer's & dementia (01.12.2021)
Published in Alzheimer's & dementia (01.12.2021)
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AD‐causing variants that affect PSEN1 transmembrane domains are associated with faster neurodegeneration and cognitive decline compared to those affecting cytoplasmic domains
Schultz, Stephanie A., Allegri, Ricardo Francisco, Schultz, Aaron P., Goate, Alison, Levey, Allan I., Fagan, Anne M., Hanseeuw, Bernard J, Koeppe, Robert A., Gordon, Brian A., Cruchaga, Carlos, Karch, Celeste M., Chen, Charles D., Xiong, Chengjie, Jack, Clifford R., Fitzpatrick, Colleen D, McDade, Eric, Chui, Helena C, Mori, Hiroshi, Lee, Jae‐Hong, Noble, James M, Hassenstab, Jason J., Levin, Johannes, Morris, John C., Johnson, Keith A., Liu, Lei, Farlow, Martin R., Jucker, Mathias, Farrell, Michelle E., Graff‐Radford, Neill R., Joseph‐Mathurin, Nelly, Fox, Nick C, Schofield, Peter R, Martins, Ralph N, Sanchez‐Valle, Raquel, Perrin, Richard J., Berman, Sarah, Salloway, Stephen P., Shirzadi, Zahra, Rosa‐Neto, Pedro, Benzinger, Tammie L.S., Bateman, Randall J., Sperling, Reisa A., Chhatwal, Jasmeer P.
Published in Alzheimer's & dementia (01.12.2022)
Published in Alzheimer's & dementia (01.12.2022)
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Journal Article
Modeling autosomal dominant Alzheimer's disease with machine learning
Luckett, Patrick H., McCullough, Austin, Gordon, Brian A., Strain, Jeremy, Flores, Shaney, Dincer, Aylin, McCarthy, John, Kuffner, Todd, Stern, Ari, Meeker, Karin L., Berman, Sarah B., Chhatwal, Jasmeer P., Cruchaga, Carlos, Fagan, Anne M., Farlow, Martin R., Fox, Nick C., Jucker, Mathias, Levin, Johannes, Masters, Colin L., Mori, Hiroshi, Noble, James M., Salloway, Stephen, Schofield, Peter R., Brickman, Adam M., Brooks, William S., Cash, David M., Fulham, Michael J., Ghetti, Bernardino, Jack, Clifford R., Vöglein, Jonathan, Klunk, William, Koeppe, Robert, Oh, Hwamee, Su, Yi, Weiner, Michael, Wang, Qing, Swisher, Laura, Marcus, Dan, Koudelis, Deborah, Joseph‐Mathurin, Nelly, Cash, Lisa, Hornbeck, Russ, Xiong, Chengjie, Perrin, Richard J., Karch, Celeste M., Hassenstab, Jason, McDade, Eric, Morris, John C., Benzinger, Tammie L.S., Bateman, Randall J., Ances, Beau M.
Published in Alzheimer's & dementia (01.06.2021)
Published in Alzheimer's & dementia (01.06.2021)
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VALIDATING NON-AMYLOID, NON-TAU CSF BIOMARKERS FOR ALZHEIMER'S DISEASE IN THE PRE-SYMPTOMATIC, MCI, AND DEMENTIA STAGES: A MULTI-CENTER STUDY
Gangishetti, Umesh, Perrin, Richard J., Arnold, Steven E., Fagan, Anne M., Morris, John C., Trojanowski, John Q., Hu, William T.
Published in Alzheimer's & dementia (01.07.2017)
Published in Alzheimer's & dementia (01.07.2017)
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Journal Article
Biomarker clustering in autosomal dominant Alzheimer's disease
Luckett, Patrick H., Chen, Charlie, Gordon, Brian A., Wisch, Julie, Berman, Sarah B., Chhatwal, Jasmeer P., Cruchaga, Carlos, Fagan, Anne M., Farlow, Martin R., Fox, Nick C., Jucker, Mathias, Levin, Johannes, Masters, Colin L., Mori, Hiroshi, Noble, James M., Salloway, Stephen, Schofield, Peter R., Brickman, Adam M., Brooks, William S., Cash, David M., Fulham, Michael J., Ghetti, Bernardino, Jack, Clifford R., Vöglein, Jonathan, Klunk, William E., Koeppe, Robert, Su, Yi, Weiner, Michael, Wang, Qing, Marcus, Daniel, Koudelis, Deborah, Joseph‐Mathurin, Nelly, Cash, Lisa, Hornbeck, Russ, Xiong, Chengjie, Perrin, Richard J., Karch, Celeste M., Hassenstab, Jason, McDade, Eric, Morris, John C., Benzinger, Tammie L.S., Bateman, Randall J., Ances, Beau M.
Published in Alzheimer's & dementia (01.01.2023)
Published in Alzheimer's & dementia (01.01.2023)
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