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Drugging DNA Damage Repair Pathways for Trinucleotide Repeat Expansion Diseases
Benn, Caroline L., Gibson, Karl R., Reynolds, David S.
Published in Journal of Huntington's disease (01.01.2021)
Published in Journal of Huntington's disease (01.01.2021)
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Inhibition of TRPM8 Channels Reduces Pain in the Cold Pressor Test in Humans
Winchester, Wendy J., Gore, Katrina, Glatt, Sophie, Petit, Wendy, Gardiner, Jennifer C., Conlon, Kelly, Postlethwaite, Michael, Saintot, Pierre-Philippe, Roberts, Sonia, Gosset, James R., Matsuura, Tomomi, Andrews, Mark D., Glossop, Paul A., Palmer, Michael J., Clear, Nicola, Collins, Susie, Beaumont, Kevin, Reynolds, David S.
Published in The Journal of pharmacology and experimental therapeutics (01.11.2014)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2014)
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The mouse beam walking assay offers improved sensitivity over the mouse rotarod in determining motor coordination deficits induced by benzodiazepines
Stanley, Joanna L, Lincoln, Rachael J, Brown, Terry A, McDonald, Louise M, Dawson, Gerard R, Reynolds, David S
Published in Journal of psychopharmacology (Oxford) (01.05.2005)
Published in Journal of psychopharmacology (Oxford) (01.05.2005)
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STOP knockout and NMDA NR1 hypomorphic mice exhibit deficits in sensorimotor gating
Fradley, Rosa L., O’Meara, Gillian F., Newman, Richard J., Andrieux, Annie, Job, Didier, Reynolds, David S.
Published in Behavioural brain research (08.09.2005)
Published in Behavioural brain research (08.09.2005)
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Design and Identification of a Novel, Functionally Subtype Selective GABAA Positive Allosteric Modulator (PF-06372865)
Owen, Robert M, Blakemore, David, Cao, Lishuang, Flanagan, Neil, Fish, Rebecca, Gibson, Karl R, Gurrell, Rachel, Huh, Chan Woo, Kammonen, Juha, Mortimer-Cassen, Elisabeth, Nickolls, Sarah A, Omoto, Kiyoyuki, Owen, Dafydd, Pike, Andy, Pryde, David C, Reynolds, David S, Roeloffs, Rosemarie, Rose, Colin, Stead, Clara, Takeuchi, Mifune, Warmus, Joseph S, Watson, Christine
Published in Journal of medicinal chemistry (27.06.2019)
Published in Journal of medicinal chemistry (27.06.2019)
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Pharmacology in translation: the preclinical and early clinical profile of the novel α2/3 functionally selective GABAA receptor positive allosteric modulator PF‐06372865
Nickolls, Sarah A, Gurrell, Rachel, Amerongen, Guido, Kammonen, Juha, Cao, Lishuang, Brown, Adam R, Stead, Clara, Mead, Andy, Watson, Christine, Hsu, Cathleen, Owen, Robert M, Pike, Andy, Fish, Rebecca L, Chen, Laigao, Qiu, Ruolun, Morris, Evan D, Feng, Gang, Whitlock, Mark, Gorman, Donal, Gerven, Joop, Reynolds, David S, Dua, Pinky, Butt, Richard P
Published in British journal of pharmacology (01.02.2018)
Published in British journal of pharmacology (01.02.2018)
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Design and identification of a novel, functionally subtype selective GABA A positive allosteric modulator (PF-06372865)
Owen, Robert M., Blakemore, David C, Cao, Lishuang, Flanagan, Neil, Fish, Rebecca, Gibson, Karl R, Gurrell, Rachel, Huh, Chan Woo, Kammonen, Juha, Mortimer-Cassen, Elisabeth, Nickolls, Sarah, Omoto, Kiyoyuki, Owen, Dafydd R, Pike, Andrew, Pryde, David C., Reynolds, David, Roeloffs, Rosemarie, Rose, Colin R., Stead, Clara, Takeuchi, Mifune, Warmus, Joseph S, Watson, Christine
Published in Journal of medicinal chemistry (27.06.2019)
Published in Journal of medicinal chemistry (27.06.2019)
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Photosensitive epilepsy: Robust clinical efficacy of a selective GABA potentiator
Gurrell, Rachel, Gorman, Donal, Whitlock, Mark, Ogden, Adam, Reynolds, David S, DiVentura, Bree, Abou-Khalil, Bassel, Gelfand, Michael, Pollard, John, Hogan, R Edward, Krauss, Gregory, Sperling, Michael, Vazquez, Blanca, Wechsler, Robert T, Friedman, Daniel, Butt, Richard P, French, Jacqueline
Published in Neurology (09.04.2019)
Published in Neurology (09.04.2019)
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Evidence That Sedative Effects of Benzodiazepines Involve Unexpected GABAA Receptor Subtypes: Quantitative Observation Studies in Rhesus Monkeys
Duke, Angela N., Meng, Zhiqiang, Platt, Donna M., Atack, John R., Dawson, Gerard R., Reynolds, David S., Tiruveedhula, V. V. N. Phani Babu, Li, Guanguan, Stephen, Michael Rajesh, Sieghart, Werner, Cook, James M., Rowlett, James K.
Published in The Journal of pharmacology and experimental therapeutics (01.07.2018)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2018)
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Evidence That Sedative Effects of Benzodiazepines Involve Unexpected GABA A Receptor Subtypes: Quantitative Observation Studies in Rhesus Monkeys
Duke, Angela N, Meng, Zhiqiang, Platt, Donna M, Atack, John R, Dawson, Gerard R, Reynolds, David S, Tiruveedhula, V V N Phani Babu, Li, Guanguan, Stephen, Michael Rajesh, Sieghart, Werner, Cook, James M, Rowlett, James K
Published in The Journal of pharmacology and experimental therapeutics (01.07.2018)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2018)
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γ-Aminobutyric Acid Type A Receptor β2 Subunit Mediates the Hypothermic Effect of Etomidate in Mice
Cirone, Jennifer, Rosahl, Thomas W., Reynolds, David S., Newman, Richard J., O'Meara, Gillian F., Hutson, Peter H., Wafford, Keith A.
Published in Anesthesiology (Philadelphia) (01.06.2004)
Published in Anesthesiology (Philadelphia) (01.06.2004)
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Time‐Resolved Spectroscopy and Photometry of CT Serpentis and V825 Herculis
Ringwald, F. A., Chase, Daniel W., Reynolds, David S.
Published in Publications of the Astronomical Society of the Pacific (01.11.2005)
Published in Publications of the Astronomical Society of the Pacific (01.11.2005)
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A randomised, placebo-controlled clinical trial with the α2/3/5 subunit selective GABAA positive allosteric modulator PF-06372865 in patients with chronic low back pain
Gurrell, Rachel, Dua, Pinky, Feng, Gang, Sudworth, Maria, Whitlock, Mark, Reynolds, David S., Butt, Richard P.
Published in Pain (Amsterdam) (01.09.2018)
Published in Pain (Amsterdam) (01.09.2018)
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Sedation and Anesthesia Mediated by Distinct GABAA Receptor Isoforms
Reynolds, David S, Rosahl, Thomas W, Cirone, Jennifer, O'Meara, Gillian F, Haythornthwaite, Alison, Newman, Richard J, Myers, Janice, Sur, Cyrille, Howell, Owain, Rutter, A. Richard, Atack, John, Macaulay, Alison J, Hadingham, Karen L, Hutson, Peter H, Belelli, Delia, Lambert, Jeremy J, Dawson, Gerard R, McKernan, Ruth, Whiting, Paul J, Wafford, Keith A
Published in The Journal of neuroscience (17.09.2003)
Published in The Journal of neuroscience (17.09.2003)
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