CpG methylation regulates allelic expression of GDF5 by modulating binding of SP1 and SP3 repressor proteins to the osteoarthritis susceptibility SNP rs143383
Reynard, Louise N., Bui, Catherine, Syddall, Catherine M., Loughlin, John
Published in Human genetics (01.08.2014)
Published in Human genetics (01.08.2014)
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Characterization of the Cartilage DNA Methylome in Knee and Hip Osteoarthritis
Rushton, Michael D., Reynard, Louise N., Barter, Matt J., Refaie, Ramsay, Rankin, Kenneth S., Young, David A., Loughlin, John
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.09.2014)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.09.2014)
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Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency
Dickinson, Rachel Emma, Griffin, Helen, Bigley, Venetia, Reynard, Louise N., Hussain, Rafiqul, Haniffa, Muzlifah, Lakey, Jeremy H., Rahman, Thahira, Wang, Xiao-Nong, McGovern, Naomi, Pagan, Sarah, Cookson, Sharon, McDonald, David, Chua, Ignatius, Wallis, Jonathan, Cant, Andrew, Wright, Michael, Keavney, Bernard, Chinnery, Patrick F., Loughlin, John, Hambleton, Sophie, Santibanez-Koref, Mauro, Collin, Matthew
Published in Blood (08.09.2011)
Published in Blood (08.09.2011)
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Functional Characterization of the Osteoarthritis Genetic Risk Residing at ALDH1A2 Identifies rs12915901 as a Key Target Variant
Shepherd, Colin, Zhu, Dongxing, Skelton, Andrew J., Combe, Jennifer, Threadgold, Harrison, Zhu, Linyi, Vincent, Tonia L., Stuart, Paul, Reynard, Louise N., Loughlin, John
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.10.2018)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.10.2018)
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A Bayesian network approach incorporating imputation of missing data enables exploratory analysis of complex causal biological relationships
Howey, Richard, Clark, Alexander D, Naamane, Najib, Reynard, Louise N, Pratt, Arthur G, Cordell, Heather J
Published in PLoS genetics (29.09.2021)
Published in PLoS genetics (29.09.2021)
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cAMP response element-binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis
Bui, Catherine, Barter, Matt J, Scott, Jenny L, Xu, Yaobo, Galler, Martin, Reynard, Louise N, Rowan, Andrew D, Young, David A
Published in The FASEB journal (01.07.2012)
Published in The FASEB journal (01.07.2012)
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Correlation of Infinium HumanMethylation450K and MethylationEPIC BeadChip arrays in cartilage
Cheung, Kathleen, Burgers, Marjolein J, Young, David A, Cockell, Simon, Reynard, Louise N
Published in Epigenetics (02.07.2020)
Published in Epigenetics (02.07.2020)
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A consistent and potentially exploitable response during chondrogenesis of mesenchymal stem cells from osteoarthritis patients to the protein encoded by the susceptibility gene GDF5
Ratnayake, Madhushika, Tselepi, Maria, Bloxham, Robert, Plöger, Frank, Reynard, Louise N, Loughlin, John
Published in PloS one (08.05.2017)
Published in PloS one (08.05.2017)
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Dual Proteolytic Pathways Govern Glycolysis and Immune Competence
Lu, Wei, Zhang, Yu, McDonald, David O., Jing, Huie, Carroll, Bernadette, Robertson, Nic, Zhang, Qian, Griffin, Helen, Sanderson, Sharon, Lakey, Jeremy H., Morgan, Neil V., Reynard, Louise N., Zheng, Lixin, Murdock, Heardley M., Turvey, Stuart E., Hackett, Scott J., Prestidge, Tim, Hall, Julie M., Cant, Andrew J., Matthews, Helen F., Koref, Mauro F. Santibanez, Simon, Anna Katharina, Korolchuk, Viktor I., Lenardo, Michael J., Hambleton, Sophie, Su, Helen C.
Published in Cell (18.12.2014)
Published in Cell (18.12.2014)
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Expression Analysis of the Mouse Multi-Copy X-Linked Gene Xlr-Related, Meiosis-Regulated (Xmr), Reveals That Xmr Encodes a Spermatid-Expressed Cytoplasmic Protein, SLX/XMR
Reynard, Louise N, Turner, James M.A, Cocquet, Julie, Mahadevaiah, Shantha K, Touré, Aminata, Höög, Christer, Burgoyne, Paul S
Published in Biology of reproduction (01.08.2007)
Published in Biology of reproduction (01.08.2007)
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Prioritization of PLEC and GRINA as Osteoarthritis Risk Genes Through the Identification and Characterization of Novel Methylation Quantitative Trait Loci
Rice, Sarah J., Tselepi, Maria, Sorial, Antony K., Aubourg, Guillaume, Shepherd, Colin, Almarza, David, Skelton, Andrew J., Pangou, Ioanna, Deehan, David, Reynard, Louise N., Loughlin, John
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.08.2019)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.08.2019)
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