Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice
Kraft, Andrew W, Hu, Xiaoyan, Yoon, Hyejin, Yan, Ping, Xiao, Qingli, Wang, Yan, Gil, So Chon, Brown, Jennifer, Wilhelmsson, Ulrika, Restivo, Jessica L, Cirrito, John R, Holtzman, David M, Kim, Jungsu, Pekny, Milos, Lee, Jin-Moo
Published in The FASEB journal (01.01.2013)
Published in The FASEB journal (01.01.2013)
Get more information
Journal Article
Serotonin signaling is associated with lower amyloid-β levels and plaques in transgenic mice and humans
Cirrito, John R, Disabato, Brianne M, Restivo, Jessica L, Verges, Deborah K, Goebel, Whitney D, Sathyan, Anshul, Hayreh, Davinder, D'Angelo, Gina, Benzinger, Tammie, Yoon, Hyejin, Kim, Jungsu, Morris, John C, Mintun, Mark A, Sheline, Yvette I
Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2011)
Get full text
Journal Article
A spectrum of exercise training reduces soluble Aβ in a dose-dependent manner in a mouse model of Alzheimer's disease
Moore, Kaitlin M, Girens, Renee E, Larson, Sara K, Jones, Maria R, Restivo, Jessica L, Holtzman, David M, Cirrito, John R, Yuede, Carla M, Zimmerman, Scott D, Timson, Benjamin F
Published in Neurobiology of disease (01.01.2016)
Published in Neurobiology of disease (01.01.2016)
Get full text
Journal Article
In vivo measurement of apolipoprotein E from the brain interstitial fluid using microdialysis
Ulrich, Jason D, Burchett, Jack M, Restivo, Jessica L, Schuler, Dorothy R, Verghese, Philip B, Mahan, Thomas E, Landreth, Gary E, Castellano, Joseph M, Jiang, Hong, Cirrito, John R, Holtzman, David M
Published in Molecular neurodegeneration (19.04.2013)
Published in Molecular neurodegeneration (19.04.2013)
Get full text
Journal Article
ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models
CRAMER, Paige E, CIRRITO, John R, BRUNDEN, Kurt R, WILSON, Donald A, LANDRETH, Gary E, WESSON, Daniel W, DANIEL LEE, C. Y, COLLEEN KARLO, J, ZINN, Adriana E, CASALI, Brad T, RESTIVO, Jessica L, GOEBET, Whitney D, JAMES, Michael J
Published in Science (American Association for the Advancement of Science) (23.03.2012)
Published in Science (American Association for the Advancement of Science) (23.03.2012)
Get full text
Journal Article
microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the Brain
Kim, Jaekwang, Yoon, Hyejin, Horie, Takahiro, Burchett, Jack M, Restivo, Jessica L, Rotllan, Noemi, Ramírez, Cristina M, Verghese, Philip B, Ihara, Masafumi, Hoe, Hyang-Sook, Esau, Christine, Fernández-Hernando, Carlos, Holtzman, David M, Cirrito, John R, Ono, Koh, Kim, Jungsu
Published in The Journal of neuroscience (04.11.2015)
Published in The Journal of neuroscience (04.11.2015)
Get full text
Journal Article
Acute dosing of latrepirdine (Dimebon), a possible Alzheimer therapeutic, elevates extracellular amyloid-beta levels in vitro and in vivo
Steele, John W, Kim, Soong H, Cirrito, John R, Verges, Deborah K, Restivo, Jessica L, Westaway, David, Fraser, Paul, Hyslop, Peter St George, Sano, Mary, Bezprozvanny, Ilya, Ehrlich, Michelle E, Holtzman, David M, Gandy, Sam
Published in Molecular neurodegeneration (17.12.2009)
Published in Molecular neurodegeneration (17.12.2009)
Get full text
Journal Article
Rapid in vivo measurement of β-amyloid reveals biphasic clearance kinetics in an Alzheimer's mouse model
Yuede, Carla M, Lee, Hyo, Restivo, Jessica L, Davis, Todd A, Hettinger, Jane C, Wallace, Clare E, Young, Katherine L, Hayne, Margaret R, Bu, Guojun, Li, Chen-Zhong, Cirrito, John R
Published in The Journal of experimental medicine (02.05.2016)
Published in The Journal of experimental medicine (02.05.2016)
Get full text
Journal Article
Opposing synaptic regulation of amyloid-β metabolism by NMDA receptors in vivo
Verges, Deborah K, Restivo, Jessica L, Goebel, Whitney D, Holtzman, David M, Cirrito, John R
Published in The Journal of neuroscience (03.08.2011)
Published in The Journal of neuroscience (03.08.2011)
Get full text
Journal Article
Emergence of a seizure phenotype in aged apolipoprotein epsilon 4 targeted replacement mice
Hunter, Jesse M, Cirrito, John R, Restivo, Jessica L, Kinley, Robert D, Sullivan, Patrick M, Holtzman, David M, Koger, Deanna, Delong, Cynthia, Lin, Suizhen, Zhao, Lingzhi, Liu, Feng, Bales, Kelly, Paul, Steven M
Published in Brain research (27.07.2012)
Published in Brain research (27.07.2012)
Get full text
Journal Article
Acute dosing of latrepirdine (Dimebon(TM)), a possible Alzheimer therapeutic, elevates extracellular amyloid-[beta] levels in vitro and in vivo
Steele, John W, Kim, Soong H, Cirrito, John R, Verges, Deborah K, Restivo, Jessica L, Westaway, David, Fraser, Paul, Hyslop, Peter St George, Sano, Mary, Bezprozvanny, Ilya, Ehrlich, Michelle E, Holtzman, David M, Gandy, Sam
Published in Molecular neurodegeneration (01.01.2009)
Published in Molecular neurodegeneration (01.01.2009)
Get full text
Journal Article
Rapid in vivo measurement of β-amyloid reveals biphasic clearance kinetics in an Alzheimer’s mouse model
Yuede, Carla M., Lee, Hyo, Restivo, Jessica L., Davis, Todd A., Hettinger, Jane C., Wallace, Clare E., Young, Katherine L., Hayne, Margaret R., Bu, Guojun, Li, Chen-zhong, Cirrito, John R.
Published in The Journal of cell biology (25.04.2016)
Published in The Journal of cell biology (25.04.2016)
Get full text
Journal Article
ApoE-Directed Therapeutics Rapidly Clear ß-Amyloid and Reverse Deficits in AD Mouse Models
Cramer, Paige E., Cirrito, John R., Wesson, Daniel W., Lee, C. Y. Daniel, Karlo, J. Colleen, Zinn, Adriana E., Casali, Brad T., Restivo, Jessica L., Goebel, Whitney D., James, Michael J., Brunden, Kurt R., Wilson, Donald A., Landreth, Gary E.
Published in Science (American Association for the Advancement of Science) (23.03.2012)
Get full text
Published in Science (American Association for the Advancement of Science) (23.03.2012)
Journal Article
ApoE-Directed Therapeutics Rapidly Clear [beta]-Amyloid and Reverse Deficits in AD Mouse Models
Cramer, Paige E, Cirrito, John R, Wesson, Daniel W, Lee, C Y Daniel, Karlo, J Colleen, Zinn, Adriana E, Casali, Brad T, Restivo, Jessica L, Goebel, Whitney D, James, Michael J, Brunden, Kurt R, Wilson, Donald A, Landreth, Gary E
Published in Science (American Association for the Advancement of Science) (23.03.2012)
Published in Science (American Association for the Advancement of Science) (23.03.2012)
Get full text
Journal Article
Serotonin signaling is associated with lower amyloid-[Beta] levels and plaques in transgenic mice and humans
Cirrito, John R, Disabato, Brianne M, Restivo, Jessica L, Verges, Deborah K, Goebel, Whitney D, Sathyan, Anshul, Hayreh, Davinder, D'Angelo, Gina, Benzinger, Tammie, Yoon, Hyejin, Kim, Jungsu, Morris, John C, Mintun, Mark A, Sheline, Yvette I
Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2011)
Get full text
Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2011)
Journal Article