Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome–positive chronic myelogenous leukemia in chronic phase following imatinib resistance and intolerance
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Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia
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Activity of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in the Blast Crisis of Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia with the Philadelphia Chromosome
Druker, Brian J, Sawyers, Charles L, Kantarjian, Hagop, Resta, Debra J, Reese, Sofia Fernandes, Ford, John M, Capdeville, Renaud, Talpaz, Moshe
Published in The New England journal of medicine (05.04.2001)
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Pharmacokinetics and Pharmacodynamics of Imatinib in a Phase I Trial With Chronic Myeloid Leukemia Patients
Peng, Bin, Hayes, Michael, Resta, Debra, Racine-Poon, Amy, Druker, Brian J, Talpaz, Moshe, Sawyers, Charles L, Rosamilia, Marianne, Ford, John, Lloyd, Peter, Capdeville, Renaud
Published in Journal of clinical oncology (01.03.2004)
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Imatinib mesylate (STI571) therapy for Philadelphia chromosome–positive chronic myelogenous leukemia in blast phase
Kantarjian, Hagop M., Cortes, Jorge, O'Brien, Susan, Giles, Francis J., Albitar, Maher, Rios, Mary Beth, Shan, Jianqin, Faderl, Stefan, Garcia-Manero, Guillermo, Thomas, Deborah A., Resta, Debra, Talpaz, Moshe
Published in Blood (15.05.2002)
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Treatment of Philadelphia Chromosome-positive, Accelerated-phase Chronic Myelogenous Leukemia with Imatinib Mesylate
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Published in Clinical cancer research (01.07.2002)
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Published in Clinical cancer research (01.07.2002)
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Hematologic and Cytogenetic Responses to Imatinib Mesylate in Chronic Myelogenous Leukemia
Kantarjian, Hagop, Sawyers, Charles, Hochhaus, Andreas, Guilhot, Francois, Schiffer, Charles, Gambacorti-Passerini, Carlo, Niederwieser, Dietger, Resta, Debra, Capdeville, Renaud, Zoellner, Ulrike, Talpaz, Moshe, Druker, Brian
Published in The New England journal of medicine (28.02.2002)
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The significance of myelosuppression during therapy with imatinib mesylate in patients with chronic myelogenous leukemia in chronic phase
Sneed, Thomas B., Kantarjian, Hagop M., Talpaz, Moshe, O'Brien, Susan, Rios, Mary Beth, Bekele, B. Nebiyou, Zhou, Xian, Resta, Debra, Wierda, William, Faderl, Stefan, Giles, Francis, Cortes, Jorge E.
Published in Cancer (01.01.2004)
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Imatinib mesylate for Philadelphia chromosome-positive, chronic-phase myeloid leukemia after failure of interferon-α: Follow-up results
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Published in Clinical cancer research (01.07.2002)
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Published in Clinical cancer research (01.07.2002)
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A Phase II Study of Nilotinib, a Novel Inhibitor of c-Kit, PDGFR, and Bcr-Abl, Administered to Patients with Systemic Mastocytosis
Hochhaus, Andreas, Ottmann, Oliver G., Lauber, STephanie, Hughes, Timothy, Verhoef, Gregor, Schwarer, Anthony P., Gratwohl, Alois, Rafferty, Teresa, Resta, Debra, Gattermann, Norbert
Published in Blood (16.11.2006)
Published in Blood (16.11.2006)
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Chronic myeloid leukemia following therapy with imatinib mesylate (Gleevec): Bone marrow histopathology and correlation with genetic status
FRATER, John L, TALLMAN, Martin S, VARIAKOJIS, Daina, DRUKER, Brian J, RESTA, Debra, RILEY, Mary Beth, HRISINKO, Mary Ann, PETERSON, Loann C
Published in American journal of clinical pathology (01.06.2003)
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Bcr-abl kinase inhibition as the basis of therapy for cml
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Published in Experimental hematology (01.07.2000)
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Imatinib Mesylate for Philadelphia Chromosome-positive, Chronic-Phase Myeloid Leukemia after Failure of Interferon-α
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Published in Clinical cancer research (01.07.2002)
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Published in Clinical cancer research (01.07.2002)
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Phase I trial of subcutaneous interleukin 3 in patients with refractory malignancy: hematological, immunological, and pharmacodynamic findings
BUKOWSKI, R. M, OLENCKI, T, RESTA, D, ELSON, P, FINKE, J, GUNN, H, MCLAIN, D, BUDD, G. T, SANDSTROM, K, TUASON, L, REDOVAN, C, RAYMAN, P, TUBBS, R
Published in Clinical cancer research (01.02.1996)
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Published in Clinical cancer research (01.02.1996)
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Phase I trial of recombinant interleukin 3 before and after carboplatin/etoposide chemotherapy in patients with solid tumors: a southwest oncology group study
RINEHART, J, MARGOLIN, K. A, TRIOZZI, P, HERSH, E, CAMPION, M, RESTA, D, LEVITT, D
Published in Clinical cancer research (01.10.1995)
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Published in Clinical cancer research (01.10.1995)
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Pharmacodynamics of daily subcutaneous recombinant human interleukin-3 in normal volunteers
Huhn, R D, Yurkow, E J, Kuhn, J G, Clarke, L, Gunn, H, Resta, D, Shah, R, Myers, L A, Seibold, J R
Published in Clinical pharmacology and therapeutics (01.01.1995)
Published in Clinical pharmacology and therapeutics (01.01.1995)
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In vivo effects of interleukin 3 in HIV type 1-infected patients with cytopenia
Scadden, D T, Levine, J D, Bresnahan, J, Gere, J, McGrath, J, Wang, Z, Resta, D J, Young, D, Hammer, S M
Published in AIDS research and human retroviruses (01.06.1995)
Published in AIDS research and human retroviruses (01.06.1995)
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