BET inhibition disrupts transcription but retains enhancer-promoter contact
Crump, Nicholas T, Ballabio, Erica, Godfrey, Laura, Thorne, Ross, Repapi, Emmanouela, Kerry, Jon, Tapia, Marta, Hua, Peng, Lagerholm, Christoffer, Filippakopoulos, Panagis, Davies, James O J, Milne, Thomas A
Published in Nature communications (11.01.2021)
Published in Nature communications (11.01.2021)
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Single-cell atlas of colonic CD8 + T cells in ulcerative colitis
Corridoni, Daniele, Antanaviciute, Agne, Gupta, Tarun, Fawkner-Corbett, David, Aulicino, Anna, Jagielowicz, Marta, Parikh, Kaushal, Repapi, Emmanouela, Taylor, Steve, Ishikawa, Dai, Hatano, Ryo, Yamada, Taketo, Xin, Wei, Slawinski, Hubert, Bowden, Rory, Napolitani, Giorgio, Brain, Oliver, Morimoto, Chikao, Koohy, Hashem, Simmons, Alison
Published in Nature medicine (01.09.2020)
Published in Nature medicine (01.09.2020)
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Single-cell analysis reveals the continuum of human lympho-myeloid progenitor cells
Karamitros, Dimitris, Stoilova, Bilyana, Aboukhalil, Zahra, Hamey, Fiona, Reinisch, Andreas, Samitsch, Marina, Quek, Lynn, Otto, Georg, Repapi, Emmanouela, Doondeea, Jessica, Usukhbayar, Batchimeg, Calvo, Julien, Taylor, Stephen, Goardon, Nicolas, Six, Emmanuelle, Pflumio, Francoise, Porcher, Catherine, Majeti, Ravindra, Göttgens, Berthold, Vyas, Paresh
Published in Nature immunology (01.01.2018)
Published in Nature immunology (01.01.2018)
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From Pioneer to Repressor: Bimodal foxd3 Activity Dynamically Remodels Neural Crest Regulatory Landscape In Vivo
Lukoseviciute, Martyna, Gavriouchkina, Daria, Williams, Ruth M., Hochgreb-Hagele, Tatiana, Senanayake, Upeka, Chong-Morrison, Vanessa, Thongjuea, Supat, Repapi, Emmanouela, Mead, Adam, Sauka-Spengler, Tatjana
Published in Developmental cell (03.12.2018)
Published in Developmental cell (03.12.2018)
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DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation
Godfrey, Laura, Crump, Nicholas T, Thorne, Ross, Lau, I-Jun, Repapi, Emmanouela, Dimou, Dimitra, Smith, Alastair L, Harman, Joe R, Telenius, Jelena M, Oudelaar, A Marieke, Downes, Damien J, Vyas, Paresh, Hughes, Jim R, Milne, Thomas A
Published in Nature communications (26.06.2019)
Published in Nature communications (26.06.2019)
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Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease
Gooding, Sarah, Olechnowicz, Sam W Z, Morris, Emma V, Armitage, Andrew E, Arezes, Joao, Frost, Joe, Repapi, Emmanouela, Edwards, James R, Ashley, Neil, Waugh, Craig, Gray, Nicola, Martinez-Hackert, Erik, Lim, Pei Jin, Pasricha, Sant-Rayn, Knowles, Helen, Mead, Adam J, Ramasamy, Karthik, Drakesmith, Hal, Edwards, Claire M
Published in Nature communications (04.10.2019)
Published in Nature communications (04.10.2019)
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The chromatin remodeller ATRX facilitates diverse nuclear processes, in a stochastic manner, in both heterochromatin and euchromatin
Truch, Julia, Downes, Damien J, Scott, Caroline, Gür, E Ravza, Telenius, Jelena M, Repapi, Emmanouela, Schwessinger, Ron, Gosden, Matthew, Brown, Jill M, Taylor, Stephen, Cheong, Pak Leng, Hughes, Jim R, Higgs, Douglas R, Gibbons, Richard J
Published in Nature communications (17.06.2022)
Published in Nature communications (17.06.2022)
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SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells
Chagraoui, Hedia, Kristiansen, Maiken S, Ruiz, Juan Pablo, Serra-Barros, Ana, Richter, Johanna, Hall-Ponselé, Elisa, Gray, Nicki, Waithe, Dominic, Clark, Kevin, Hublitz, Philip, Repapi, Emmanouela, Otto, Georg, Sopp, Paul, Taylor, Stephen, Thongjuea, Supat, Vyas, Paresh, Porcher, Catherine
Published in Nature communications (18.12.2018)
Published in Nature communications (18.12.2018)
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Multi-Modal Characterization of Monocytes in Idiopathic Pulmonary Fibrosis Reveals a Primed Type I Interferon Immune Phenotype
Fraser, Emily, Denney, Laura, Antanaviciute, Agne, Blirando, Karl, Vuppusetty, Chaitanya, Zheng, Yuejuan, Repapi, Emmanouela, Iotchkova, Valentina, Taylor, Stephen, Ashley, Neil, St Noble, Victoria, Benamore, Rachel, Hoyles, Rachel, Clelland, Colin, Rastrick, Joseph M D, Hardman, Clare S, Alham, Nasullah K, Rigby, Rachel E, Simmons, Alison, Rehwinkel, Jan, Ho, Ling-Pei
Published in Frontiers in immunology (05.03.2021)
Published in Frontiers in immunology (05.03.2021)
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MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia
Kerry, Jon, Godfrey, Laura, Repapi, Emmanouela, Tapia, Marta, Blackledge, Neil P., Ma, Helen, Ballabio, Erica, O’Byrne, Sorcha, Ponthan, Frida, Heidenreich, Olaf, Roy, Anindita, Roberts, Irene, Konopleva, Marina, Klose, Robert J., Geng, Huimin, Milne, Thomas A.
Published in Cell reports (Cambridge) (10.01.2017)
Published in Cell reports (Cambridge) (10.01.2017)
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Single cell spatial analysis reveals inflammatory foci of immature neutrophil and CD8 T cells in COVID-19 lungs
Weeratunga, Praveen, Denney, Laura, Bull, Joshua A., Repapi, Emmanouela, Sergeant, Martin, Etherington, Rachel, Vuppussetty, Chaitanya, Turner, Gareth D. H., Clelland, Colin, Woo, Jeongmin, Cross, Amy, Issa, Fadi, de Andrea, Carlos Eduardo, Melero Bermejo, Ignacio, Sims, David, McGowan, Simon, Zurke, Yasemin-Xiomara, Ahern, David J., Gamez, Eddie C., Whalley, Justin, Richards, Duncan, Klenerman, Paul, Monaco, Claudia, Udalova, Irina A., Dong, Tao, Antanaviciute, Agne, Ogg, Graham, Knight, Julian C., Byrne, Helen M., Taylor, Stephen, Ho, Ling-Pei
Published in Nature communications (08.11.2023)
Published in Nature communications (08.11.2023)
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Hepcidin is regulated by promoter-associated histone acetylation and HDAC3
Pasricha, Sant-Rayn, Lim, Pei Jin, Duarte, Tiago L, Casu, Carla, Oosterhuis, Dorenda, Mleczko-Sanecka, Katarzyna, Suciu, Maria, Da Silva, Ana Rita, Al-Hourani, Kinda, Arezes, João, McHugh, Kirsty, Gooding, Sarah, Frost, Joe N, Wray, Katherine, Santos, Ana, Porto, Graça, Repapi, Emmanouela, Gray, Nicki, Draper, Simon J, Ashley, Neil, Soilleux, Elizabeth, Olinga, Peter, Muckenthaler, Martina U, Hughes, Jim R, Rivella, Stefano, Milne, Thomas A, Armitage, Andrew E, Drakesmith, Hal
Published in Nature communications (01.09.2017)
Published in Nature communications (01.09.2017)
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Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation
Di Genua, Cristina, Norfo, Ruggiero, Rodriguez-Meira, Alba, Wen, Wei Xiong, Drissen, Roy, Booth, Christopher A G, Povinelli, Benjamin, Repapi, Emmanouela, Gray, Nicki, Carrelha, Joana, Kettyle, Laura M, Jamieson, Lauren, Neo, Wen Hao, Thongjuea, Supat, Nerlov, Claus, Mead, Adam J
Published in Haematologica (Roma) (01.11.2019)
Published in Haematologica (Roma) (01.11.2019)
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CD1a presentation of endogenous antigens by group 2 innate lymphoid cells
Hardman, Clare S, Chen, Yi-Ling, Salimi, Maryam, Jarrett, Rachael, Johnson, David, Järvinen, Valtteri J, Owens, Raymond J, Repapi, Emmanouela, Cousins, David J, Barlow, Jillian L, McKenzie, Andrew N J, Ogg, Graham
Published in Science immunology (22.12.2017)
Published in Science immunology (22.12.2017)
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Journal Article
Does osteogenic potential of clonal human bone marrow mesenchymal stem/stromal cells correlate with their vascular supportive ability?
Merryweather-Clarke, Alison T, Cook, David, Lara, Barbara Joo, Hua, Peng, Repapi, Emmanouela, Ashley, Neil, Lim, Shiang Y, Watt, Suzanne M
Published in Stem cell research & therapy (19.12.2018)
Published in Stem cell research & therapy (19.12.2018)
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No evidence for age-related differences in mitochondrial RNA quality in the female germline
Hartley, Fiona, Alageel, Arwa, Appeltant, Ruth, Gray, Nicki, Repapi, Emmanouela, Wells, Dagan, Williams, Suzannah A, Poulton, Joanna
Published in Reproduction & fertility (01.07.2022)
Published in Reproduction & fertility (01.07.2022)
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A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample
Obeidat, Ma'en, Wain, Louise V, Shrine, Nick, Kalsheker, Noor, Soler Artigas, Maria, Repapi, Emmanouela, Burton, Paul R, Johnson, Toby, Ramasamy, Adaikalavan, Zhao, Jing Hua, Zhai, Guangju, Huffman, Jennifer E, Vitart, Veronique, Albrecht, Eva, Igl, Wilmar, Hartikainen, Anna-Liisa, Pouta, Anneli, Cadby, Gemma, Hui, Jennie, Palmer, Lyle J, Hadley, David, McArdle, Wendy L, Rudnicka, Alicja R, Barroso, Inês, Loos, Ruth J F, Wareham, Nicholas J, Mangino, Massimo, Soranzo, Nicole, Spector, Tim D, Gläser, Sven, Homuth, Georg, Völzke, Henry, Deloukas, Panos, Granell, Raquel, Henderson, John, Grkovic, Ivica, Jankovic, Stipan, Zgaga, Lina, Polašek, Ozren, Rudan, Igor, Wright, Alan F, Campbell, Harry, Wild, Sarah H, Wilson, James F, Heinrich, Joachim, Imboden, Medea, Probst-Hensch, Nicole M, Gyllensten, Ulf, Johansson, Åsa, Zaboli, Ghazal, Mustelin, Linda, Rantanen, Taina, Surakka, Ida, Kaprio, Jaakko, Jarvelin, Marjo-Riitta, Hayward, Caroline, Evans, David M, Koch, Beate, Musk, Arthur William, Elliott, Paul, Strachan, David P, Tobin, Martin D, Sayers, Ian, Hall, Ian P
Published in PloS one (20.05.2011)
Published in PloS one (20.05.2011)
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The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes
Yip, Bon Ham, Steeples, Violetta, Repapi, Emmanouela, Armstrong, Richard N, Llorian, Miriam, Roy, Swagata, Shaw, Jacqueline, Dolatshad, Hamid, Taylor, Stephen, Verma, Amit, Bartenstein, Matthias, Vyas, Paresh, Cross, Nicholas Cp, Malcovati, Luca, Cazzola, Mario, Hellström-Lindberg, Eva, Ogawa, Seishi, Smith, Christopher Wj, Pellagatti, Andrea, Boultwood, Jacqueline
Published in The Journal of clinical investigation (01.06.2017)
Published in The Journal of clinical investigation (01.06.2017)
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A Comprehensive Analysis of the Impact of HIV on HCV Immune Responses and Its Association with Liver Disease Progression in a Unique Plasma Donor Cohort
Zhang, Yong-Hong, Zhao, Yan, Rajapaksa, Ushani S, Lawrence, Tessa M, Peng, Yan-Chun, Liu, Jinghua, Xu, Keyi, Hu, Ke, Qin, Ling, Liu, Ning, Sun, Huanqin, Yan, Hui-Ping, Repapi, Emmanouela, Rowland-Jones, Sarah, Thimme, Robert, McKeating, Jane A, Dong, Tao
Published in PloS one (25.07.2016)
Published in PloS one (25.07.2016)
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