Spatial immunophenotypes predict response to anti-PD1 treatment and capture distinct paths of T cell evasion in triple negative breast cancer
Hammerl, Dora, Martens, John W. M., Timmermans, Mieke, Smid, Marcel, Trapman-Jansen, Anita M., Foekens, Renée, Isaeva, Olga I., Voorwerk, Leonie, Balcioglu, Hayri E., Wijers, Rebecca, Nederlof, Iris, Salgado, Roberto, Horlings, Hugo, Kok, Marleen, Debets, Reno
Published in Nature communications (27.09.2021)
Published in Nature communications (27.09.2021)
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Journal Article
Adoptive T Cell Therapy: New Avenues Leading to Safe Targets and Powerful Allies
Hammerl, Dora, Rieder, Dietmar, Martens, John W.M., Trajanoski, Zlatko, Debets, Reno
Published in Trends in immunology (01.11.2018)
Published in Trends in immunology (01.11.2018)
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Journal Article
Enhanced recruitment of genetically modified CX3CR1-positive human T cells into Fractalkine/CX3CL1 expressing tumors: importance of the chemokine gradient
Siddiqui, Imran, Erreni, Marco, van Brakel, Mandy, Debets, Reno, Allavena, Paola
Published in Journal for immunotherapy of cancer (19.04.2016)
Published in Journal for immunotherapy of cancer (19.04.2016)
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Journal Article
Cancer germline antigens and tumor-agnostic CD8+ T cell evasion
Kortleve, Dian, Coelho, Rui M.L., Hammerl, Dora, Debets, Reno
Published in Trends in immunology (01.05.2022)
Published in Trends in immunology (01.05.2022)
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Journal Article
T-cell Receptors for Clinical Therapy: In Vitro Assessment of Toxicity Risk
Kunert, Andre, Obenaus, Matthias, Lamers, Cor H J, Blankenstein, Thomas, Debets, Reno
Published in Clinical cancer research (15.10.2017)
Published in Clinical cancer research (15.10.2017)
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Journal Article
Transient cell-in-cell formation underlies tumor relapse and resistance to immunotherapy
Gutwillig, Amit, Santana-Magal, Nadine, Farhat-Younis, Leen, Rasoulouniriana, Diana, Madi, Asaf, Luxenburg, Chen, Cohen, Jonathan, Padmanabhan, Krishnanand, Shomron, Noam, Shapira, Guy, Gleiberman, Annette, Parikh, Roma, Levy, Carmit, Feinmesser, Meora, Hershkovitz, Dov, Zemser-Werner, Valentina, Zlotnik, Oran, Kroon, Sanne, Hardt, Wolf-Dietrich, Debets, Reno, Reticker-Flynn, Nathan Edward, Rider, Peleg, Carmi, Yaron
Published in eLife (20.09.2022)
Published in eLife (20.09.2022)
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Journal Article
Triple-Negative Breast Cancer and Predictive Markers of Response to Neoadjuvant Chemotherapy: A Systematic Review
van den Ende, Nadine S, Nguyen, Anh H, Jager, Agnes, Kok, Marleen, Debets, Reno, van Deurzen, Carolien H M
Published in International journal of molecular sciences (03.02.2023)
Published in International journal of molecular sciences (03.02.2023)
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Journal Article
Immunotherapy in Glioblastoma: Current Shortcomings and Future Perspectives
Weenink, Bas, French, Pim J, Sillevis Smitt, Peter A E, Debets, Reno, Geurts, Marjolein
Published in Cancers (22.03.2020)
Published in Cancers (22.03.2020)
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Journal Article
Curdlan, zymosan and a yeast-derived β-glucan reshape tumor-associated macrophages into producers of inflammatory chemo-attractants
de Graaff, Priscilla, Berrevoets, Cor, Rӧsch, Christiane, Schols, Henk A., Verhoef, Kees, Wichers, Harry J., Debets, Reno, Govers, Coen
Published in Cancer Immunology, Immunotherapy (01.02.2021)
Published in Cancer Immunology, Immunotherapy (01.02.2021)
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Journal Article
Epithelial-Mesenchymal Transition in Human Prostate Cancer Demonstrates Enhanced Immune Evasion Marked by IDO1 Expression
Kolijn, Kimberley, Verhoef, Esther I, Smid, Marcel, Böttcher, René, Jenster, Guido W, Debets, Reno, van Leenders, Geert J L H
Published in Cancer research (Chicago, Ill.) (15.08.2018)
Published in Cancer research (Chicago, Ill.) (15.08.2018)
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Journal Article
Overt Thyroid Dysfunction and Anti-Thyroid Antibodies Predict Response to Anti-PD-1 Immunotherapy in Cancer Patients
Basak, Edwin A, van der Meer, Jan W M, Hurkmans, Daan P, Schreurs, Marco W J, Oomen-de Hoop, Esther, van der Veldt, Astrid A M, Bins, Sander, Joosse, Arjen, Koolen, Stijn L W, Debets, Reno, Peeters, Robin P, Aerts, Joachim G J V, Mathijssen, Ron H J, Medici, Marco
Published in Thyroid (New York, N.Y.) (01.07.2020)
Published in Thyroid (New York, N.Y.) (01.07.2020)
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Journal Article
T lymphocytes facilitate brain metastasis of breast cancer by inducing Guanylate-Binding Protein 1 expression
Mustafa, Dana A. M., Pedrosa, Rute M. S. M., Smid, Marcel, van der Weiden, Marcel, de Weerd, Vanja, Nigg, Alex L., Berrevoets, Cor, Zeneyedpour, Lona, Priego, Neibla, Valiente, Manuel, Luider, Theo M., Debets, Reno, Martens, John W. M., Foekens, John A., Sieuwerts, Anieta M., Kros, Johan M.
Published in Acta neuropathologica (01.04.2018)
Published in Acta neuropathologica (01.04.2018)
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Journal Article
Tumor-infiltrating lymphocytes and ductal carcinoma in situ of the breast: friends or foes?
Agahozo, Marie Colombe, Hammerl, Dora, Debets, Reno, Kok, Marleen, van Deurzen, Carolien H M
Published in Modern pathology (01.07.2018)
Published in Modern pathology (01.07.2018)
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Journal Article
Correlation between nivolumab exposure and treatment outcomes in non–small-cell lung cancer
Basak, Edwin A., Koolen, Stijn L.W., Hurkmans, Daan P., Schreurs, Marco W.J., Bins, Sander, Oomen – de Hoop, Esther, Wijkhuijs, Annemarie J.M., Besten, Ilse den, Sleijfer, Stefan, Debets, Reno, van der Veldt, Astrid A.M., Aerts, Joachim G.J.V., Mathijssen, Ron H.J.
Published in European journal of cancer (1990) (01.03.2019)
Published in European journal of cancer (1990) (01.03.2019)
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Journal Article
Low-grade glioma harbors few CD8 T cells, which is accompanied by decreased expression of chemo-attractants, not immunogenic antigens
Weenink, Bas, Draaisma, Kaspar, Ooi, Han Z., Kros, Johan M., Sillevis Smitt, Peter A. E., Debets, Reno, French, Pim J.
Published in Scientific reports (10.10.2019)
Published in Scientific reports (10.10.2019)
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Journal Article
The in vivo therapeutic efficacy of the oncolytic adenovirus Delta24-RGD is mediated by tumor-specific immunity
Kleijn, Anne, Kloezeman, Jenneke, Treffers-Westerlaken, Elike, Fulci, Giulia, Leenstra, Sieger, Dirven, Clemens, Debets, Reno, Lamfers, Martine
Published in PloS one (27.05.2014)
Published in PloS one (27.05.2014)
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Journal Article
Differential quantities of immune checkpoint-expressing CD8 T cells in soft tissue sarcoma subtypes
Klaver, Yarne, Rijnders, Maud, Oostvogels, Astrid, Wijers, Rebecca, Smid, Marcel, Grünhagen, Dirk, Verhoef, Kees, Sleijfer, Stefan, Lamers, Cor, Debets, Reno
Published in Journal for immunotherapy of cancer (01.08.2020)
Published in Journal for immunotherapy of cancer (01.08.2020)
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Journal Article
Continuous Exposure to Non-Soluble β-Glucans Induces Trained Immunity in M-CSF-Differentiated Macrophages
Moerings, Bart G. J., de Graaff, Priscilla, Furber, Matthew, Witkamp, Renger F., Debets, Reno, Mes, Jurriaan J., van Bergenhenegouwen, Jeroen, Govers, Coen
Published in Frontiers in immunology (02.06.2021)
Published in Frontiers in immunology (02.06.2021)
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Journal Article
Vγ9Vδ2 T Cells Concurrently Kill Cancer Cells and Cross-Present Tumor Antigens
Holmen Olofsson, Gitte, Idorn, Manja, Carnaz Simões, Ana Micaela, Aehnlich, Pia, Skadborg, Signe Koggersbøl, Noessner, Elfriede, Debets, Reno, Moser, Bernhard, Met, Özcan, thor Straten, Per
Published in Frontiers in immunology (02.06.2021)
Published in Frontiers in immunology (02.06.2021)
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Journal Article
HYpofractionated, dose-redistributed RAdiotherapy with protons and photons to combat radiation-induced immunosuppression in head and neck squamous cell carcinoma: study protocol of the phase I HYDRA trial
Elbers, Joris B W, Gunsch, Pascal A, Debets, Reno, Keereweer, Stijn, van Meerten, Esther, Zindler, Jaap, van Norden, Yvette, Hoogeman, Mischa S, Verduijn, Gerda M, Kroesen, Michiel, Nout, Remi A
Published in BMC cancer (13.06.2023)
Published in BMC cancer (13.06.2023)
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