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Published in Cell (31.05.2018)
Published in Cell (31.05.2018)
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Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB
Brummelkamp, Thijn R, Nijman, Sebastian M B, Dirac, Annette M G, Bernards, René
Published in Nature (London) (14.08.2003)
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Published in Nature (London) (14.08.2003)
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An Experimenter’s Guide to Glioblastoma Invasion Pathways
de Gooijer, Mark C., Guillén Navarro, Miriam, Bernards, Rene, Wurdinger, Thomas, van Tellingen, Olaf
Published in Trends in molecular medicine (01.09.2018)
Published in Trends in molecular medicine (01.09.2018)
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Identifying mutant-specific multi-drug combinations using comparative network reconstruction
Bosdriesz, Evert, Fernandes Neto, João M., Sieber, Anja, Bernards, René, Blüthgen, Nils, Wessels, Lodewyk F.A.
Published in iScience (19.08.2022)
Published in iScience (19.08.2022)
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MammaPrint and BluePrint Molecular Diagnostics Using Targeted RNA Next-Generation Sequencing Technology
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Published in The Journal of molecular diagnostics : JMD (01.09.2019)
Published in The Journal of molecular diagnostics : JMD (01.09.2019)
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A roadmap for the next decade in cancer research
Bernards, René, Jaffee, Elizabeth, Joyce, Johanna A, Lowe, Scott W, Mardis, Elaine R, Morrison, Sean J, Polyak, Kornelia, Sears, Cynthia L, Vousden, Karen H, Zhang, Zemin
Published in Nature cancer (01.01.2020)
Published in Nature cancer (01.01.2020)
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A System-wide Approach to Monitor Responses to Synergistic BRAF and EGFR Inhibition in Colorectal Cancer Cells
Ressa, Anna, Bosdriesz, Evert, de Ligt, Joep, Mainardi, Sara, Maddalo, Gianluca, Prahallad, Anirudh, Jager, Myrthe, de la Fonteijne, Lisanne, Fitzpatrick, Martin, Groten, Stijn, Altelaar, A.F. Maarten, Bernards, René, Cuppen, Edwin, Wessels, Lodewyk, Heck, Albert J.R.
Published in Molecular & cellular proteomics (01.10.2018)
Published in Molecular & cellular proteomics (01.10.2018)
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The consensus molecular subtypes of colorectal cancer
Guinney, Justin, Dienstmann, Rodrigo, Wang, Xin, de Reyniès, Aurélien, Schlicker, Andreas, Soneson, Charlotte, Marisa, Laetitia, Roepman, Paul, Nyamundanda, Gift, Angelino, Paolo, Bot, Brian M, Morris, Jeffrey S, Simon, Iris M, Gerster, Sarah, Fessler, Evelyn, De Sousa E Melo, Felipe, Missiaglia, Edoardo, Ramay, Hena, Barras, David, Homicsko, Krisztian, Maru, Dipen, Manyam, Ganiraju C, Broom, Bradley, Boige, Valerie, Perez-Villamil, Beatriz, Laderas, Ted, Salazar, Ramon, Gray, Joe W, Hanahan, Douglas, Tabernero, Josep, Bernards, Rene, Friend, Stephen H, Laurent-Puig, Pierre, Medema, Jan Paul, Sadanandam, Anguraj, Wessels, Lodewyk, Delorenzi, Mauro, Kopetz, Scott, Vermeulen, Louis, Tejpar, Sabine
Published in Nature medicine (01.11.2015)
Published in Nature medicine (01.11.2015)
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BRCA1-like signature in triple negative breast cancer: Molecular and clinical characterization reveals subgroups with therapeutic potential
Severson, Tesa M., Peeters, Justine, Majewski, Ian, Michaut, Magali, Bosma, Astrid, Schouten, Philip C., Chin, Suet-Feung, Pereira, Bernard, Goldgraben, Mae A., Bismeijer, Tycho, Kluin, Roelof J.C., Muris, Jettie J.F., Jirström, Karin, Kerkhoven, Ron M., Wessels, Lodewyk, Caldas, Carlos, Bernards, René, Simon, Iris M., Linn, Sabine
Published in Molecular oncology (01.10.2015)
Published in Molecular oncology (01.10.2015)
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An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors
Bernards, René, Beijersbergen, Roderick L, Brummelkamp, Thijn R, Fabius, Armida W M, Mullenders, Jasper, Madiredjo, Mandy, Velds, Arno, Kerkhoven, Ron M
Published in Nature chemical biology (01.04.2006)
Published in Nature chemical biology (01.04.2006)
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Publisher Correction: Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability
Geijer, Marit E., Zhou, Di, Selvam, Kathiresan, Steurer, Barbara, Mukherjee, Chirantani, Evers, Bastiaan, Cugusi, Simona, van Toorn, Marvin, van der Woude, Melanie, Janssens, Roel C., Kok, Yannick P., Gong, Wenzhi, Raams, Anja, Lo, Calvin S. Y., Lebbink, Joyce H. G., Geverts, Bart, Plummer, Dalton A., Bezstarosti, Karel, Theil, Arjan F., Mitter, Richard, Houtsmuller, Adriaan B., Vermeulen, Wim, Demmers, Jeroen A. A., Li, Shisheng, van Vugt, Marcel A. T. M., Lans, Hannes, Bernards, René, Svejstrup, Jesper Q., Ray Chaudhuri, Arnab, Wyrick, John J., Marteijn, Jurgen A.
Published in Nature cell biology (01.07.2021)
Published in Nature cell biology (01.07.2021)
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Targeting of vulnerabilities of drug-tolerant persisters identified through functional genetics delays tumor relapse
Chen, Mengnuo, Mainardi, Sara, Lieftink, Cor, Velds, Arno, de Rink, Iris, Yang, Chen, Kuiken, Hendrik J., Morris, Ben, Edwards, Finn, Jochems, Fleur, van Tellingen, Olaf, Boeije, Manon, Proost, Natalie, Jansen, Robin A., Qin, Shifan, Jin, Haojie, Koen van der Mijn, J.C., Schepers, Arnout, Venkatesan, Subramanian, Qin, Wenxin, Beijersbergen, Roderick L., Wang, Liqin, Bernards, René
Published in Cell reports. Medicine (19.03.2024)
Published in Cell reports. Medicine (19.03.2024)
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Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma
Sun, Chong, Wang, Liqin, Huang, Sidong, Heynen, Guus J. J. E., Prahallad, Anirudh, Robert, Caroline, Haanen, John, Blank, Christian, Wesseling, Jelle, Willems, Stefan M., Zecchin, Davide, Hobor, Sebastijan, Bajpe, Prashanth K., Lieftink, Cor, Mateus, Christina, Vagner, Stephan, Grernrum, Wipawadee, Hofland, Ingrid, Schlicker, Andreas, Wessels, Lodewyk F. A., Beijersbergen, Roderick L., Bardelli, Alberto, Di Nicolantonio, Federica, Eggermont, Alexander M. M., Bernards, Rene
Published in Nature (London) (03.04.2014)
Published in Nature (London) (03.04.2014)
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NF-κB drives acquired resistance to a novel mutant-selective EGFR inhibitor
Galvani, Elena, Sun, Jing, Leon, Leticia G, Sciarrillo, Rocco, Narayan, Ravi S, Sjin, Robert Tjin Tham, Lee, Kwangho, Ohashi, Kadoaki, Heideman, Daniëlle A M, Alfieri, Roberta R, Heynen, Guus J, Bernards, René, Smit, Egbert F, Pao, William, Peters, Godefridus J, Giovannetti, Elisa
Published in Oncotarget (15.12.2015)
Published in Oncotarget (15.12.2015)
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A combined oncogenic pathway signature of BRAF, KRAS and PI3KCA mutation improves colorectal cancer classification and cetuximab treatment prediction
Tian, Sun, Simon, Iris, Moreno, Victor, Roepman, Paul, Tabernero, Josep, Snel, Mireille, van't Veer, Laura, Salazar, Ramon, Bernards, Rene, Capella, Gabriel
Published in Gut (01.04.2013)
Published in Gut (01.04.2013)
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Correction to: A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers
Šuštić, Tonći, van Wageningen, Sake, Bosdriesz, Evert, Reid, Robert J D, Dittmar, John, Lieftink, Cor, Beijersbergen, Roderick L, Wessels, Lodewyk F A, Rothstein, Rodney, Bernards, René
Published in Genome medicine (10.02.2021)
Published in Genome medicine (10.02.2021)
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Reply to Eliezer M. Van Allen, Levi A. Garraway and Jonathan E. Rosenberg's Letter to the Editor re: Floris H. Groenendijk, Jeroen de Jong, Elisabeth E. Fransen van de Putte, et al. ERBB2 Mutations Characterize a Subgroup of Muscle-invasive Bladder Cancers with Excellent Response to Neoadjuvant Chemotherapy. Eur Urol. In press. http://dx.doi.org/10.1016/j.eururo.2015.01.014
Groenendijk, Floris H, Fransen van de Putte, Elisabeth E, van Rhijn, Bas W.G, Bernards, René, van der Heijden, Michiel S
Published in European urology (01.08.2015)
Published in European urology (01.08.2015)
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