The Fetal Mouse Is a Sensitive Genotoxicity Model That Exposes Lentiviral-associated Mutagenesis Resulting in Liver Oncogenesis
Nowrouzi, Ali, Cheung, Wing T, Li, Tingting, Zhang, Xuegong, Arens, Anne, Paruzynski, Anna, Waddington, Simon N, Osejindu, Emma, Reja, Safia, von Kalle, Christof, Wang, Yoahe, Al-Allaf, Faisal, Gregory, Lisa, Themis, Matthew, Holder, Maxine, Dighe, Niraja, Ruthe, Alaine, Buckley, Suzanne MK, Bigger, Brian, Montini, Eugenio, Thrasher, Adrian J, Andrews, Robert, Roberts, Terry P, Newbold, Robert F, Coutelle, Charles, Schmidt, Manfred, Themis, Mike
Published in Molecular therapy (01.02.2013)
Published in Molecular therapy (01.02.2013)
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Journal Article
Oncogenesis following vector delivery in the fetal mouse appears to be independent of WPRE-presence in vector constructs and supports this animal model for assessment of vector-associated genotoxicity
Nowrouzi, Ali, Cheung, Wing, Li, Tingting, Zhang, Xuegong, Arens, Anne, Paruzynski, Anna, Waddington, Simon N, Osejindu, Emma, Reja, Safia, von Kalle, Christof
Published in Molecular therapy (01.09.2012)
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Published in Molecular therapy (01.09.2012)
Journal Article