In vitro characterization of SLV308 (7-[4-methyl-1-piperazinyl]-2(3H)-benzoxazolone, monohydrochloride): A novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist
Glennon, Jeffrey C., Van Scharrenburg, Guus, Ronken, Eric, Hesselink, Mayke B., Reinders, Jan-Hendrik, Van Der Neut, Martina, Long, Stephen K., Feenstra, Rolf W., McCreary, Andrew C.
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Published in Synapse (New York, N.Y.) (15.12.2006)
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Potent dihydroquinolinone dopamine D2 partial agonist/serotonin reuptake inhibitors for the treatment of schizophrenia
YINFA YAN, PING ZHOU, CARRICK, Tikva, MARQUIS, Karen L, PAUSCH, Mark H, ROBICHAUD, Albert J, ROTELLA, David P, FEENSTRA, Rolf, KRUSE, Chris G, REINDERS, Jan-Hendrik, VAN DER NEUT, Martina, LAI, Margaret, ZHANG, Jean, KOWAL, Dianne M
Published in Bioorganic & medicinal chemistry letters (01.05.2010)
Published in Bioorganic & medicinal chemistry letters (01.05.2010)
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Tetrahydrocarbazole-based serotonin reuptake inhibitor/dopamine D2 partial agonists for the potential treatment of schizophrenia
ROTELLA, David P, MCFARLANE, Geraldine R, MCCREARY, Andrew, KRUSE, Chris G, SULLIVAN, Kelly, PRUTHI, Farhana, LAI, Margaret, ZHANG, Jean, KOWAL, Dianne M, CARRICK, Tikva, GRAUER, Steven M, NAVARRA, Rachel L, GREENFIELD, Alexander, GRAF, Radka, BRENNAN, Julie, MARQUIS, Karen L, PAUSCH, Mark H, GROSANU, Cristina, ROBICHAUD, Albert J, DENNY, Rajiah Aldrin, FEENSTRA, Rolf W, NUNEZ-GARCIA, Sara, REINDERS, Jan-Hendrik, VAN DER NEUT, Martina
Published in Bioorganic & medicinal chemistry letters (01.10.2009)
Published in Bioorganic & medicinal chemistry letters (01.10.2009)
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Principal Component Analysis Differentiates the Receptor Binding Profiles of Three Antipsychotic Drug Candidates from Current Antipsychotic Drugs
Lange, Jos H. M, Reinders, Jan-Hendrik, Tolboom, Jeroen T. B. M, Glennon, Jeffrey C, Coolen, Hein K. A. C, Kruse, Chris G
Published in Journal of medicinal chemistry (18.10.2007)
Published in Journal of medicinal chemistry (18.10.2007)
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Design and Synthesis of an orally active GPIIb/IIIa antagonist based on a phenylpiperazine scaffold
van Maarseveen, Jan H, den Hartog, Jack A.J, Tipker, Koos, Reinders, Jan-Hendrik, Brakkee, Joost, Schön, Uwe, Kehrbach, Wolfgang, Kruse, Chris G
Published in Bioorganic & medicinal chemistry letters (16.06.1998)
Published in Bioorganic & medicinal chemistry letters (16.06.1998)
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Potent dihydroquinolinone dopamine D 2 partial agonist/serotonin reuptake inhibitors for the treatment of schizophrenia
Yan, Yinfa, Zhou, Ping, Rotella, David P., Feenstra, Rolf, Kruse, Chris G., Reinders, Jan-Hendrik, Neut, Martina van der, Lai, Margaret, Zhang, Jean, Kowal, Dianne M., Carrick, Tikva, Marquis, Karen L., Pausch, Mark H., Robichaud, Albert J.
Published in Bioorganic & medicinal chemistry letters (01.05.2010)
Published in Bioorganic & medicinal chemistry letters (01.05.2010)
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Isolation of a storage and secretory organelle containing Von Willebrand protein from cultured human endothelial cells
Reinders, Jan Hendrik, De Groot, Philip G., Gonsalves, Mervin D., Zandbergen, Joke, Loesberg, Cornelia, Van Mourik, Jan A.
Published in Biochimica et biophysica acta (20.07.1984)
Published in Biochimica et biophysica acta (20.07.1984)
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Tetrahydrocarbazole-based serotonin reuptake inhibitor/dopamine D 2 partial agonists for the potential treatment of schizophrenia
Rotella, David P., McFarlane, Geraldine R., Greenfield, Alexander, Grosanu, Cristina, Robichaud, Albert J., Denny, Rajiah Aldrin, Feenstra, Rolf W., Núñez-García, Sara, Reinders, Jan-Hendrik, Neut, Martina van der, McCreary, Andrew, Kruse, Chris G., Sullivan, Kelly, Pruthi, Farhana, Lai, Margaret, Zhang, Jean, Kowal, Dianne M., Carrick, Tikva, Grauer, Steven M., Navarra, Rachel L., Graf, Radka, Brennan, Julie, Marquis, Karen L., Pausch, Mark H.
Published in Bioorganic & medicinal chemistry letters (01.10.2009)
Published in Bioorganic & medicinal chemistry letters (01.10.2009)
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Potent dihydroquinolinone dopamine D sub(2) partial agonist/serotonin reuptake inhibitors for the treatment of schizophrenia
Yan, Yinfa, Zhou, Ping, Rotella, David P, Feenstra, Rolf, Kruse, Chris G, Reinders, Jan-Hendrik, Van der Neut, Martina, Lai, Margaret, Zhang, Jean, Kowal, Dianne M, Carrick, Tikva, Marquis, Karen L, Pausch, Mark H, Robichaud, Albert J
Published in Bioorganic & medicinal chemistry letters (01.05.2010)
Published in Bioorganic & medicinal chemistry letters (01.05.2010)
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7-Azaindole derivatives as potential partial nicotinic agonists
Stoit, Axel R., den Hartog, Arnold P., Mons, Harry, van Schaik, Sjoerd, Barkhuijsen, Nynke, Stroomer, Cees, Coolen, Hein K.A.C., Reinders, Jan Hendrik, Adolfs, Tiny J.P., van der Neut, Martina, Keizer, Hiskias, Kruse, Chris G.
Published in Bioorganic & medicinal chemistry (2008)
Published in Bioorganic & medicinal chemistry (2008)
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Tetrahydrocarbazole-based serotonin reuptake inhibitor/dopamine D sub(2) partial agonists for the potential treatment of schizophrenia
Rotella, David P, McFarlane, Geraldine R, Greenfield, Alexander, Grosanu, Cristina, Robichaud, Albert J, Denny, Rajiah Aldrin, Feenstra, Rolf W, Nunez-Garcia, Sara, Reinders, Jan-Hendrik, Van der Neut, Martina, McCreary, Andrew, Kruse, Chris G, Sullivan, Kelly, Pruthi, Farhana, Lai, Margaret, Zhang, Jean, Kowal, Dianne M, Carrick, Tikva, Grauer, Steven M, Navarra, Rachel L, Graf, Radka, Brennan, Julie, Marquis, Karen L, Pausch, Mark H
Published in Bioorganic & medicinal chemistry letters (01.10.2009)
Published in Bioorganic & medicinal chemistry letters (01.10.2009)
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SLV313 (1 -(2,3 -dihydro -benzo [1,4 ]dioxin -5 -yl ) -4-[5-(4-fluoro-phenyl)-pyridin-3-ylmethyl]-piperazine monohydrochloride) : A novel dopamine D2 receptor antagonist and 5-HTIA receptor agonist potential antipsychotic drug
MCCREARY, Andrew C, GLENNON, Jeffrey C, FEENSTRA, Rolf W, KRUSE, Chris G, ASHBY, Charles R, MELTZER, Herbert Y, ZHU LI, REINDERS, Jan-Hendrik, HESSELINK, Mayke B, LONG, Stephen K, HERREMANS, Arnoud H, VAN STUIVENBERG, Herman
Published in Neuropsychopharmacology (New York, N.Y.) (2007)
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Published in Neuropsychopharmacology (New York, N.Y.) (2007)
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SLV313 (1-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-4- [5-(4-fluoro-phenyl)-pyridin-3-ylmethyl]-piperazine monohydrochloride): a novel dopamine D2 receptor antagonist and 5-HT1A receptor agonist potential antipsychotic drug
McCreary, Andrew C, Glennon, Jeffrey C, Ashby, Jr, Charles R, Meltzer, Herbert Y, Li, Zhu, Reinders, Jan-Hendrik, Hesselink, Mayke B, Long, Stephen K, Herremans, Arnoud H, van Stuivenberg, Herman, Feenstra, Rolf W, Kruse, Chris G
Published in Neuropsychopharmacology (New York, N.Y.) (01.01.2007)
Published in Neuropsychopharmacology (New York, N.Y.) (01.01.2007)
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Comparison of secretion and subcellular localization of von Willebrand protein with that of thrombospondin and fibronectin in cultured human vascular endothelial cells
Reinders, Jan Hendrik, de Groot, Philip G., Dawes, Joan, Hunter, Nikolas R., van Heugten, Henricus A.A., Zandbergen, Joke, Gonsalves, Mervin D., van Mourik, Jan A.
Published in Biochimica et biophysica acta. Molecular cell research (21.03.1985)
Published in Biochimica et biophysica acta. Molecular cell research (21.03.1985)
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Perturbation of cultured human vascular endothelial cells by phorbol ester or thrombin alters the cellular von Willebrand factor distribution
Reinders, J H, Vervoorn, R C, Verweij, C L, van Mourik, J A, de Groot, P G
Published in Journal of cellular physiology (01.10.1987)
Published in Journal of cellular physiology (01.10.1987)
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