Diet-driven microbial ecology underpins associations between cancer immunotherapy outcomes and the gut microbiome
Simpson, Rebecca C., Shanahan, Erin R., Batten, Marcel, Reijers, Irene L. M., Read, Mark, Silva, Ines P., Versluis, Judith M., Ribeiro, Rosilene, Angelatos, Alexandra S., Tan, Jian, Adhikari, Chandra, Menzies, Alexander M., Saw, Robyn P. M., Gonzalez, Maria, Shannon, Kerwin F., Spillane, Andrew J., Velickovic, Rebecca, Lazar, Alexander J., Damania, Ashish V., Mishra, Aditya K., Chelvanambi, Manoj, Banerjee, Anik, Ajami, Nadim J., Wargo, Jennifer A., Macia, Laurence, Holmes, Andrew J., Wilmott, James S., Blank, Christian U., Scolyer, Richard A., Long, Georgina V.
Published in Nature medicine (01.11.2022)
Published in Nature medicine (01.11.2022)
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Representativeness of the Index Lymph Node for Total Nodal Basin in Pathologic Response Assessment After Neoadjuvant Checkpoint Inhibitor Therapy in Patients With Stage III Melanoma
Reijers, Irene L. M, Rawson, Robert V, Colebatch, Andrew J, Rozeman, Elisa A, Menzies, Alex M, van Akkooi, Alexander C. J, Shannon, Kerwin F, Wouters, Michel W, Saw, Robyn P. M, van Houdt, Winan J, Zuur, Charlotte L, Nieweg, Omgo E, Ch’ng, Sydney, Klop, W. Martin C, Spillane, Andrew J, Long, Georgina V, Scolyer, Richard A, van de Wiel, Bart A, Blank, Christian U
Published in JAMA surgery (01.04.2022)
Published in JAMA surgery (01.04.2022)
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Association between pretreatment emotional distress and neoadjuvant immune checkpoint blockade response in melanoma
Fraterman, Itske, Reijers, Irene L. M., Dimitriadis, Petros, Broeks, Annegien, Gonzalez, M., Menzies, A. M. M., Lopez-Yurda, Marta, Kapiteijn, Ellen, van der Veldt, Astrid A. M., Suijkerbuijk, Karijn P. M., Hospers, Geke A. P., Long, Georgina V., Blank, Christian U., van de Poll-Franse, Lonneke V.
Published in Nature medicine (01.12.2023)
Published in Nature medicine (01.12.2023)
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Personalized response-directed surgery and adjuvant therapy after neoadjuvant ipilimumab and nivolumab in high-risk stage III melanoma: the PRADO trial
Reijers, Irene L. M., Menzies, Alexander M., van Akkooi, Alexander C. J., Versluis, Judith M., van den Heuvel, Noëlle M. J., Saw, Robyn P. M., Pennington, Thomas E., Kapiteijn, Ellen, van der Veldt, Astrid A. M., Suijkerbuijk, Karijn P. M., Hospers, Geke A. P., Rozeman, Elisa A., Klop, Willem M. C., van Houdt, Winan J., Sikorska, Karolina, van der Hage, Jos A., Grünhagen, Dirk J., Wouters, Michel W., Witkamp, Arjen J., Zuur, Charlotte L., Lijnsvelt, Judith M., Torres Acosta, Alejandro, Grijpink-Ongering, Lindsay G., Gonzalez, Maria, Jóźwiak, Katarzyna, Bierman, Carolien, Shannon, Kerwin F., Ch’ng, Sydney, Colebatch, Andrew J., Spillane, Andrew J., Haanen, John B. A. G., Rawson, Robert V., van de Wiel, Bart A., van de Poll-Franse, Lonneke V., Scolyer, Richard A., Boekhout, Annelies H., Long, Georgina V., Blank, Christian U.
Published in Nature medicine (01.06.2022)
Published in Nature medicine (01.06.2022)
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Ipilimumab alone or ipilimumab plus anti-PD-1 therapy in patients with metastatic melanoma resistant to anti-PD-(L)1 monotherapy: a multicentre, retrospective, cohort study
Pires da Silva, Ines, Ahmed, Tasnia, Reijers, Irene L M, Weppler, Alison M, Betof Warner, Allison, Patrinely, James Randall, Serra-Bellver, Patricio, Allayous, Clara, Mangana, Joanna, Nguyen, Khang, Zimmer, Lisa, Trojaniello, Claudia, Stout, Dan, Lyle, Megan, Klein, Oliver, Gerard, Camille L, Michielin, Olivier, Haydon, Andrew, Ascierto, Paolo A, Carlino, Matteo S, Lebbe, Celeste, Lorigan, Paul, Johnson, Douglas B, Sandhu, Shahneen, Lo, Serigne N, Blank, Christian U, Menzies, Alexander M, Long, Georgina V
Published in The lancet oncology (01.06.2021)
Published in The lancet oncology (01.06.2021)
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IFN-γ signature enables selection of neoadjuvant treatment in patients with stage III melanoma
Reijers, Irene L M, Rao, Disha, Versluis, Judith M, Menzies, Alexander M, Dimitriadis, Petros, Wouters, Michel W, Spillane, Andrew J, Klop, Willem M C, Broeks, Annegien, Bosch, Linda J W, Lopez-Yurda, Marta, van Houdt, Winan J, Rawson, Robert V, Grijpink-Ongering, Lindsay G, Gonzalez, Maria, Cornelissen, Sten, Bouwman, Jasper, Sanders, Joyce, Plasmeijer, Elsemieke, Elshot, Yannick S, Scolyer, Richard A, van de Wiel, Bart A, Peeper, Daniel S, van Akkooi, Alexander C J, Long, Georgina V, Blank, Christian U
Published in The Journal of experimental medicine (01.05.2023)
Published in The Journal of experimental medicine (01.05.2023)
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Switch to checkpoint inhibition after targeted therapy at time of progression or during ongoing response: A retrospective single‐centre experience in patients with BRAF‐mutated melanoma
Reijers, Irene L. M., Rozeman, Elisa A., Wilgenhof, Sofie, Thienen, Johannes V., Haanen, John B. A. G., Blank, Christian U.
Published in Pigment cell and melanoma research (01.05.2020)
Published in Pigment cell and melanoma research (01.05.2020)
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Inhibitor of Apoptosis Proteins Antagonist Induces T-cell Proliferation after Cross-Presentation by Dendritic Cells
Hoefsmit, Esmée P, van Royen, Paula T, Rao, Disha, Stunnenberg, Johanna A, Dimitriadis, P, Lieftink, Cor, Morris, Ben, Rozeman, Elisa A, Reijers, Irene L M, Lacroix, Ruben, Shehwana, Huma, Ligtenberg, Maarten A, Beijersbergen, Roderick L, Peeper, Daniel S, Blank, Christian U
Published in Cancer immunology research (03.04.2023)
Published in Cancer immunology research (03.04.2023)
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Neoadjuvant ipilimumab plus nivolumab in synchronous clinical stage III melanoma
Versluis, Judith M., Reijers, Irene L.M., Rozeman, Elisa A., Menzies, Alexander M., van Akkooi, Alexander C.J., Wouters, Michel W., Ch'ng, Sydney, Saw, Robyn P.M., Scolyer, Richard A., van de Wiel, Bart A., Schilling, Bastian, Long, Georgina V., Blank, Christian U.
Published in European journal of cancer (1990) (01.05.2021)
Published in European journal of cancer (1990) (01.05.2021)
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Impact of personalized response-directed surgery and adjuvant therapy on survival after neoadjuvant immunotherapy in stage III melanoma: comparison of 3-year data from PRADO and OpACIN-neo
Reijers, Irene LM, Menzies, Alexander M, Lopez-Yurda, Marta, Versluis, Judith M, Rozeman, Elisa A, Saw, Robyn PM, van Houdt, Winan J, Kapiteijn, Ellen, van der Veldt, Astrid AM, Suijkerbuijk, Karijn PM, Eriksson, Hanna, Hospers, Geke AP, MC Klop, Willem, Acosta, Alejandro Torres, Grijpink-Ongering, Lindsay, Gonzalez, Maria, van der Wal, Anja, Al-Mamgani, Abrahim, Spillane, Andrew J, Scolyer, Richard A, van de Wiel, Bart A, van Akkooi, Alexander CJ, Long, Georgina V, Blank, Christian U
Published in European journal of cancer (1990) (19.11.2024)
Published in European journal of cancer (1990) (19.11.2024)
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Systemic LRG1 Expression in Melanoma is Associated with Disease Progression and Recurrence
Hoefsmit, Esmee P, Völlmy, Franziska, Rozeman, Elisa A, Reijers, Irene L M, Versluis, Judith M, Hoekman, Liesbeth, van Akkooi, Alexander C J, Long, Georgina V, Schadendorf, Dirk, Dummer, Reinhard, Altelaar, Maarten, Blank, Christian U
Published in Cancer research communications (01.04.2023)
Published in Cancer research communications (01.04.2023)
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Biomarker-Driven Personalization of Neoadjuvant Immunotherapy in Melanoma
Hoeijmakers, Lotte L, Reijers, Irene L M, Blank, Christian U
Published in Cancer discovery (01.11.2023)
Published in Cancer discovery (01.11.2023)
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Journal Article
Ipilimumab versus ipilimumab plus anti-PD-1 for metastatic melanoma – Authors' reply
da Silva, Ines Pires, Ahmed, Tasnia, Reijers, Irene L M, Warner, Allison Betof, Patrinely, James Randall, Serra-Bellver, Patricio, Allayous, Clara, Mangana, Joanna, Zimmer, Lisa, Trojaniello, Claudia, Klein, Oliver, Gerard, Camille L, Michielin, Olivier, Haydon, Andrew, Ascierto, Paolo A, Carlino, Matteo S, Lebbe, Celeste, Lorigan, Paul, Johnson, Douglas B, Sandhu, Shahneen, Lo, Serigne N, Menzies, Alexander M, Long, Georgina V
Published in The lancet oncology (01.08.2021)
Published in The lancet oncology (01.08.2021)
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Journal Article
Neoadjuvant Nivolumab and Ipilimumab in Resectable Stage III Melanoma
Blank, Christian U, Lucas, Minke W, Scolyer, Richard A, van de Wiel, Bart A, Menzies, Alexander M, Lopez-Yurda, Marta, Hoeijmakers, Lotte L, Saw, Robyn P M, Lijnsvelt, Judith M, Maher, Nigel G, Pulleman, Saskia M, Gonzalez, Maria, Torres Acosta, Alejandro, van Houdt, Winan J, Lo, Serigne N, Kuijpers, Anke M J, Spillane, Andrew, Klop, W Martin C, Pennington, Thomas E, Zuur, Charlotte L, Shannon, Kerwin F, Seinstra, Beatrijs A, Rawson, Robert V, Haanen, John B A G, Ch'ng, Sydney, Naipal, Kishan A T, Stretch, Jonathan, van Thienen, Johannes V, Rtshiladze, Michael A, Wilgenhof, Sofie, Kapoor, Rony, Meerveld-Eggink, Aafke, Grijpink-Ongering, Lindsay G, van Akkooi, Alexander C J, Reijers, Irene L M, Gyorki, David E, Grünhagen, Dirk J, Speetjens, Frank M, Vliek, Sonja B, Placzke, Joanna, Spain, Lavinia, Stassen, Robert C, Amini-Adle, Mona, Lebbé, Céleste, Faries, Mark B, Robert, Caroline, Ascierto, Paolo A, van Rijn, Rozemarijn, van den Berkmortel, Franchette W P J, Piersma, Djura, van der Westhuizen, Andre, Vreugdenhil, Gerard, Aarts, Maureen J B, Stevense-den Boer, Marion A M, Atkinson, Victoria, Khattak, Muhammad, Andrews, Miles C, van den Eertwegh, Alfons J M, Boers-Sonderen, Marye J, Hospers, Geke A P, Carlino, Matteo S, de Groot, Jan-Willem B, Kapiteijn, Ellen, Suijkerbuijk, Karijn P M, Rutkowski, Piotr, Sandhu, Shahneen, van der Veldt, Astrid A M, Long, Georgina V
Published in The New England journal of medicine (07.11.2024)
Published in The New England journal of medicine (07.11.2024)
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