NTP42, a novel antagonist of the thromboxane receptor, attenuates experimentally induced pulmonary arterial hypertension
Mulvaney, Eamon P, Reid, Helen M, Bialesova, Lucia, Bouchard, Annie, Salvail, Dany, Kinsella, B Therese
Published in BMC pulmonary medicine (06.04.2020)
Published in BMC pulmonary medicine (06.04.2020)
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Journal Article
Evaluation of NTP42 , a novel thromboxane receptor antagonist, in a first-in-human phase I clinical trial
Reid, Helen M, Maginn, Mark, Perkins, C Michael, Mulvaney, Eamon P, Boyce, Malcolm, Yamamoto, Takahiro, Kinsella, B Therese
Published in Frontiers in pharmacology (21.12.2023)
Published in Frontiers in pharmacology (21.12.2023)
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Journal Article
The thromboxane receptor antagonist NTP42 promotes beneficial adaptation and preserves cardiac function in experimental models of right heart overload
Mulvaney, Eamon P, Renzo, Fabiana, Adão, Rui, Dupre, Emilie, Bialesova, Lucia, Salvatore, Viviana, Reid, Helen M, Conceição, Glória, Grynblat, Julien, Llucià-Valldeperas, Aida, Michel, Jean-Baptiste, Brás-Silva, Carmen, Laurent, Charles E, Howard, Luke S, Montani, David, Humbert, Marc, Vonk Noordegraaf, Anton, Perros, Frédéric, Mendes-Ferreira, Pedro, Kinsella, B Therese
Published in Frontiers in cardiovascular medicine (14.12.2022)
Published in Frontiers in cardiovascular medicine (14.12.2022)
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Journal Article
Efficacy of the thromboxane receptor antagonist NTP42 alone, or in combination with sildenafil, in the sugen/hypoxia-induced model of pulmonary arterial hypertension
Mulvaney, Eamon P., Reid, Helen M., Bialesova, Lucia, Mendes-Ferreira, Pedro, Adão, Rui, Brás-Silva, Carmen, Kinsella, B. Therese
Published in European journal of pharmacology (15.12.2020)
Published in European journal of pharmacology (15.12.2020)
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Journal Article
Interaction of the human prostacyclin receptor with Rab11. Characterization of a novel Rab11 binding domain within α-helix 8 that is regulated by palmitoylation
Reid, Helen M, Mulvaney, Eamon P, Turner, Elizebeth C, Kinsella, B Therese
Published in The Journal of biological chemistry (03.08.2018)
Published in The Journal of biological chemistry (03.08.2018)
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Journal Article
Urocortin-2 improves right ventricular function and attenuates pulmonary arterial hypertension
Adão, Rui, Mendes-Ferreira, Pedro, Santos-Ribeiro, Diana, Maia-Rocha, Carolina, Pimentel, Luís D, Monteiro-Pinto, Cláudia, Mulvaney, Eamon P, Reid, Helen M, Kinsella, B Therese, Potus, François, Breuils-Bonnet, Sandra, Rademaker, Miriam T, Provencher, Steeve, Bonnet, Sébastien, Leite-Moreira, Adelino F, Brás-Silva, Carmen
Published in Cardiovascular research (01.07.2018)
Published in Cardiovascular research (01.07.2018)
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Journal Article
Prostacyclin receptors: Transcriptional regulation and novel signalling mechanisms
Reid, Helen M., Kinsella, B. Therese
Published in Prostaglandins & other lipid mediators (01.09.2015)
Published in Prostaglandins & other lipid mediators (01.09.2015)
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Journal Article
Identification of an interaction between the TPα and TPβ isoforms of the human thromboxane A2 receptor with protein kinase C-related kinase (PRK) 1. Implications for prostate cancer
Turner, Elizebeth C, Kavanagh, David J, Mulvaney, Eamon P, McLean, Caitriona, Wikström, Katarina, Reid, Helen M, Kinsella, B Therese
Published in The Journal of biological chemistry (03.08.2018)
Published in The Journal of biological chemistry (03.08.2018)
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Journal Article
IHG-1 increases mitochondrial fusion and bioenergetic function
Hickey, Fionnuala B, Corcoran, James B, Griffin, Brenda, Bhreathnach, Una, Mortiboys, Heather, Reid, Helen M, Andrews, Darrell, Byrne, Shane, Furlong, Fiona, Martin, Finian, Godson, Catherine, Murphy, Madeline
Published in Diabetes (New York, N.Y.) (01.12.2014)
Published in Diabetes (New York, N.Y.) (01.12.2014)
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Journal Article
Differential expression of the TPα and TPβ isoforms of the human T Prostanoid receptor during chronic inflammation of the prostate: Role for FOXP1 in the transcriptional regulation of TPβ during monocyte-macrophage differentiation
Mulvaney, Eamon P., O'Sullivan, Áine G., Eivers, Sarah B., Reid, Helen M., Kinsella, B. Therese
Published in Experimental and molecular pathology (01.10.2019)
Published in Experimental and molecular pathology (01.10.2019)
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Journal Article
In Vitro and in Vivo Pharmacological Characterization of BM-613 [N-n-Pentyl-Nâ²-[2-(4â²-methylphenylamino)-5-nitrobenzenesulfonyl]urea], a Novel Dual Thromboxane Synthase Inhibitor and Thromboxane Receptor Antagonist
Hanson, Julien, Rolin, Stephanie, Reynaud, Denis, Qiao, Na, Kelley, Leanne P, Reid, Helen M, Valentin, François, Tippins, John, Kinsella, B Therese, Masereel, Bernard, Pace-Asciak, Cecil, Pirotte, Bernard, Dogné, Jean-Michel
Published in The Journal of pharmacology and experimental therapeutics (01.04.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2005)
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Journal Article
Interaction of the Human Prostacyclin Receptor with Rab11: CHARACTERIZATION OF A NOVEL Rab11 BINDING DOMAIN WITHIN α-HELIX 8 THAT IS REGULATED BY PALMITOYLATION
Reid, Helen M., Mulvaney, Eamon P., Turner, Elizebeth C., Kinsella, B. Therese
Published in The Journal of biological chemistry (11.06.2010)
Published in The Journal of biological chemistry (11.06.2010)
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Journal Article
Transcriptional regulation of the human thromboxane A2 receptor gene by Wilms' tumor (WT)1 and hypermethylated in cancer (HIC) 1 in prostate and breast cancers
Keating, Garret L., Reid, Helen M., Eivers, Sarah B., Mulvaney, Eamon P., Kinsella, B. Therese
Published in Biochimica et biophysica acta (01.06.2014)
Published in Biochimica et biophysica acta (01.06.2014)
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Journal Article
Identification of a novel endoplasmic reticulum export motif within the eighth α-helical domain (α-H8) of the human prostacyclin receptor
Donnellan, Peter D., Kimbembe, Cisca C., Reid, Helen M., Kinsella, B. Therese
Published in Biochimica et biophysica acta (01.04.2011)
Published in Biochimica et biophysica acta (01.04.2011)
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Journal Article
Interaction of the human prostacyclin receptor and the NHERF4 family member intestinal and kidney enriched PDZ protein (IKEPP)
Reid, Helen M., Turner, Elizebeth C., Mulvaney, Eamon P., Hyland, Paula B., McLean, Caitriona, Kinsella, B. Therese
Published in Biochimica et biophysica acta (01.10.2012)
Published in Biochimica et biophysica acta (01.10.2012)
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