Down-regulation of the expression of cyclooxygenase-2 and prostaglandin E2 by interleukin-4 is mediated via a reduction in the expression of prostanoid EP4 receptors in HCA-7 human colon cancer cells
Kitagawa, Kana, Hamaguchi, Ayaka, Fukushima, Keijo, Nakano, Yuki, Regan, John W., Mashimo, Masato, Fujino, Hiromichi
Published in European journal of pharmacology (05.04.2022)
Published in European journal of pharmacology (05.04.2022)
Get full text
Journal Article
Prostaglandin E2 Induced Functional Expression of Early Growth Response Factor-1 by EP4, but Not EP2, Prostanoid Receptors via the Phosphatidylinositol 3-Kinase and Extracellular Signal-regulated Kinases
Fujino, Hiromichi, Xu, Wei, Regan, John W
Published in The Journal of biological chemistry (04.04.2003)
Published in The Journal of biological chemistry (04.04.2003)
Get full text
Journal Article
Enzymes and Receptors of Prostaglandin Pathways with Arachidonic Acid-derived Versus Eicosapentaenoic Acid-derived Substrates and Products
Wada, Masayuki, DeLong, Cynthia J., Hong, Yu H., Rieke, Caroline J., Song, Inseok, Sidhu, Ranjinder S., Yuan, Chong, Warnock, Mark, Schmaier, Alvin H., Yokoyama, Chieko, Smyth, Emer M., Wilson, Stephen J., FitzGerald, Garret A., Garavito, R. Michael, Sui, De Xin, Regan, John W., Smith, William L.
Published in The Journal of biological chemistry (03.08.2007)
Published in The Journal of biological chemistry (03.08.2007)
Get full text
Journal Article
Human DP and EP2 prostanoid receptors take on distinct forms depending on the diverse binding of different ligands
Suganami, Akiko, Fujino, Hiromichi, Okura, Iori, Yanagisawa, Naoki, Sugiyama, Hajime, Regan, John W., Tamura, Yutaka, Murayama, Toshihiko
Published in The FEBS journal (01.11.2016)
Published in The FEBS journal (01.11.2016)
Get full text
Journal Article
Phosphorylation of Glycogen Synthase Kinase-3 and Stimulation of T-cell Factor Signaling following Activation of EP2 and EP4 Prostanoid Receptors by Prostaglandin E2
Fujino, Hiromichi, West, Kimberly A., Regan, John W.
Published in The Journal of biological chemistry (25.01.2002)
Published in The Journal of biological chemistry (25.01.2002)
Get full text
Journal Article
Prostaglandin E2-stimulated prostanoid EP4 receptors induce prolonged de novo prostaglandin E2 synthesis through biphasic phosphorylation of extracellular signal-regulated kinases mediated by activation of protein kinase A in HCA-7 human colon cancer cells
Fujino, Hiromichi, Seira, Naofumi, Kurata, Naoki, Araki, Yumi, Nakamura, Hiroyuki, Regan, John W., Murayama, Toshihiko
Published in European journal of pharmacology (05.12.2015)
Published in European journal of pharmacology (05.12.2015)
Get full text
Journal Article
Anti-cancer Effects of MW-03, a Novel Indole Compound, by Inducing 15-Hydroxyprostaglandin Dehydrogenase and Cellular Growth Inhibition in the LS174T Human Colon Cancer Cell Line
Seira, Naofumi, Yanagisawa, Naoki, Suganami, Akiko, Honda, Takuya, Wasai, Makiko, Regan, John W., Fukushima, Keijo, Yamaguchi, Naoto, Tamura, Yutaka, Arai, Takayoshi, Murayama, Toshihiko, Fujino, Hiromichi
Published in Biological & pharmaceutical bulletin (2017)
Published in Biological & pharmaceutical bulletin (2017)
Get full text
Journal Article
Prostaglandin E₂ regulates cellular migration via induction of vascular endothelial growth factor receptor-1 in HCA-7 human colon cancer cells
Fujino, Hiromichi, Toyomura, Kaori, Chen, Xiao-bo, Regan, John W, Murayama, Toshihiko
Published in Biochemical pharmacology (01.02.2011)
Published in Biochemical pharmacology (01.02.2011)
Get full text
Journal Article
Prostanoid receptors and phosphatidylinositol 3-kinase: a pathway to cancer?
Fujino, Hiromichi, Regan, John W.
Published in Trends in pharmacological sciences (Regular ed.) (01.07.2003)
Published in Trends in pharmacological sciences (Regular ed.) (01.07.2003)
Get full text
Journal Article
A novel indole compound, AWT-489, inhibits prostaglandin D2-induced CD55 expression by acting on DP prostanoid receptors as an antagonist in LS174T human colon cancer cells
Oyama, Satomi, Fujino, Hiromichi, Yamazaki, Risa, Okura, Iori, Regan, John W., Awata, Atsuko, Arai, Takayoshi, Murayama, Toshihiko
Published in Archives of biochemistry and biophysics (01.01.2014)
Published in Archives of biochemistry and biophysics (01.01.2014)
Get full text
Journal Article
The induction of S100p expression by the Prostaglandin E2 (PGE2)/EP4 receptor signaling pathway in colon cancer cells
Chandramouli, Anupama, Mercado-Pimentel, Melania E., Hutchinson, Anthony, Gibadulinová, Adriana, Olson, Erik R., Dickinson, Sally, Shañas, Reneé, Davenport, Jennifer, Owens, Janae, Bhattacharyya, Achyut K., Regan, John W., Pastorekova, Silvia, Arumugam, Thiruvengadam, Logsdon, Craig D., Nelson, Mark A.
Published in Cancer biology & therapy (15.11.2010)
Published in Cancer biology & therapy (15.11.2010)
Get full text
Journal Article
Down-regulation of the expression of cyclooxygenase-2 and prostaglandin E 2 by interleukin-4 is mediated via a reduction in the expression of prostanoid EP4 receptors in HCA-7 human colon cancer cells
Kitagawa, Kana, Hamaguchi, Ayaka, Fukushima, Keijo, Nakano, Yuki, Regan, John W, Mashimo, Masato, Fujino, Hiromichi
Published in European journal of pharmacology (05.04.2022)
Published in European journal of pharmacology (05.04.2022)
Get full text
Journal Article
Short chain fatty acid butyrate uptake reduces expressions of prostanoid EP4 receptors and their mediation of cyclooxygenase-2 induction in HCA-7 human colon cancer cells
Kurata, Naoki, Tokashiki, Natsumi, Fukushima, Keijo, Misao, Takaya, Hasuoka, Nanae, Kitagawa, Kana, Mashimo, Masato, Regan, John W., Murayama, Toshihiko, Fujino, Hiromichi
Published in European journal of pharmacology (15.06.2019)
Published in European journal of pharmacology (15.06.2019)
Get full text
Journal Article
15-Keto-PGE2 acts as a biased/partial agonist to terminate PGE2-evoked signaling
Endo, Suzu, Suganami, Akiko, Fukushima, Keijo, Senoo, Kanaho, Araki, Yumi, Regan, John W., Mashimo, Masato, Tamura, Yutaka, Fujino, Hiromichi
Published in The Journal of biological chemistry (18.09.2020)
Published in The Journal of biological chemistry (18.09.2020)
Get full text
Journal Article
FP Prostanoid Receptor-Mediated Induction of the Expression of Early Growth Response Factor-1 by Activation of a Ras/Raf/Mitogen-Activated Protein Kinase Signaling Cascade
Xu, Wei, Chou, Chih-Ling, Sun, Haipeng, Fujino, Hiromichi, Chen, Qin M, Regan, John W
Published in Molecular pharmacology (01.01.2008)
Published in Molecular pharmacology (01.01.2008)
Get full text
Journal Article