In Silico Prediction of Cytochrome P450 2D6 and 3A4 Inhibition Using Gaussian Kernel Weighted k-Nearest Neighbor and Extended Connectivity Fingerprints, Including Structural Fragment Analysis of Inhibitors versus Noninhibitors
Jensen, Berith F, Vind, Christian, Brockhoff, Per B, Refsgaard, Hanne H. F
Published in Journal of medicinal chemistry (08.02.2007)
Published in Journal of medicinal chemistry (08.02.2007)
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Journal Article
Molecular Engineering of Insulin Icodec, the First Acylated Insulin Analog for Once-Weekly Administration in Humans
Kjeldsen, Thomas B, Hubálek, František, Hjørringgaard, Claudia U, Tagmose, Tina M, Nishimura, Erica, Stidsen, Carsten E, Porsgaard, Trine, Fledelius, Christian, Refsgaard, Hanne H. F, Gram-Nielsen, Sanne, Naver, Helle, Pridal, Lone, Hoeg-Jensen, Thomas, Jeppesen, Claus Bekker, Manfè, Valentina, Ludvigsen, Svend, Lautrup-Larsen, Inger, Madsen, Peter
Published in Journal of medicinal chemistry (08.07.2021)
Published in Journal of medicinal chemistry (08.07.2021)
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Journal Article
Elucidating the Mechanism of Absorption of Fast-Acting Insulin Aspart: The Role of Niacinamide
Kildegaard, Jonas, Buckley, Stephen T., Nielsen, Rasmus H., Povlsen, Gro K., Seested, Torben, Ribel, Ulla, Olsen, Helle B., Ludvigsen, Svend, Jeppesen, Claus B., Refsgaard, Hanne H. F., Bendtsen, Kristian M., Kristensen, Niels R., Hostrup, Susanne, Sturis, Jeppe
Published in Pharmaceutical research (01.03.2019)
Published in Pharmaceutical research (01.03.2019)
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Journal Article
Molecular engineering of safe and efficacious oral basal insulin
Hubálek, Frantisek, Refsgaard, Hanne H. F., Gram-Nielsen, Sanne, Madsen, Peter, Nishimura, Erica, Münzel, Martin, Brand, Christian Lehn, Stidsen, Carsten Enggaard, Claussen, Christian Hove, Wulff, Erik Max, Pridal, Lone, Ribel, Ulla, Kildegaard, Jonas, Porsgaard, Trine, Johansson, Eva, Steensgaard, Dorte Bjerre, Hovgaard, Lars, Glendorf, Tine, Hansen, Bo Falck, Jensen, Maja Kirkegaard, Nielsen, Peter Kresten, Ludvigsen, Svend, Rugh, Susanne, Garibay, Patrick W., Moore, Mary Courtney, Cherrington, Alan D., Kjeldsen, Thomas
Published in Nature communications (27.07.2020)
Published in Nature communications (27.07.2020)
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Journal Article
Author Correction: Molecular engineering of safe and efficacious oral basal insulin
Hubálek, Frantisek, Refsgaard, Hanne H. F., Gram-Nielsen, Sanne, Madsen, Peter, Nishimura, Erica, Münzel, Martin, Brand, Christian Lehn, Stidsen, Carsten Enggaard, Claussen, Christian Hove, Wulff, Erik Max, Pridal, Lone, Ribel, Ulla, Kildegaard, Jonas, Porsgaard, Trine, Johansson, Eva, Steensgaard, Dorte Bjerre, Hovgaard, Lars, Glendorf, Tine, Hansen, Bo Falck, Jensen, Maja Kirkegaard, Nielsen, Peter Kresten, Ludvigsen, Svend, Rugh, Susanne, Garibay, Patrick W., Moore, Mary Courtney, Cherrington, Alan D., Kjeldsen, Thomas
Published in Nature communications (20.08.2020)
Published in Nature communications (20.08.2020)
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Journal Article
Modifications of Proteins by Polyunsaturated Fatty Acid Peroxidation Products
Hanne H. F. Refsgaard, Tsai, Lin, Stadtman, Earl R.
Published in Proceedings of the National Academy of Sciences - PNAS (18.01.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (18.01.2000)
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Journal Article
Predicting human half-life for insulin analogs: An inter-drug approach
Bendtsen, Kristian M., Harder, Magnus W.H., Glendorf, Tine, Kjeldsen, Thomas B., Kristensen, Niels R., Refsgaard, Hanne H.F.
Published in European journal of pharmaceutics and biopharmaceutics (01.08.2024)
Published in European journal of pharmaceutics and biopharmaceutics (01.08.2024)
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Journal Article
Engineering of Orally Available, Ultralong-Acting Insulin Analogues: Discovery of OI338 and OI320
Kjeldsen, Thomas B., Hubalek, Frantisek, Tagmose, Tina M., Pridal, Lone, Refsgaard, Hanne H. F., Porsgaard, Trine, Gram-Nielsen, Sanne, Hovgaard, Lars, Valore, Henrik, Munzel, Martin, Hjorringgaard, Claudia U., Jeppesen, Claus Bekker, Manfe, Valentina, Hoeg-Jensen, Thomas, Ludvigsen, Svend, Nielsen, Peter Kresten, Lautrup-Larsen, Inger, Stidsen, Carsten E., Wulff, Erik M., Garibay, Patrick W., Kodra, Janos T., Nishimura, Erica, Madsen, Peter
Published in Journal of medicinal chemistry (14.01.2021)
Published in Journal of medicinal chemistry (14.01.2021)
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Journal Article
Glucose-sensitive insulin with attenuation of hypoglycaemia
Hoeg-Jensen, Thomas, Kruse, Thomas, Brand, Christian L., Sturis, Jeppe, Fledelius, Christian, Nielsen, Peter K., Nishimura, Erica, Madsen, Alice R., Lykke, Lennart, Halskov, Kim S., Koščová, Simona, Kotek, Vladislav, Davis, Anthony P., Tromans, Robert A., Tomsett, Michael, Peñuelas-Haro, Guillem, Leonard, Daniel J., Orchard, Michael G., Chapman, Andy, Invernizzi, Gaetano, Johansson, Eva, Granata, Daniele, Hansen, Bo F., Pedersen, Thomas A., Kildegaard, Jonas, Pedersen, Karen-Margrethe, Refsgaard, Hanne H. F., Alifrangis, Lene, Fels, Johannes J., Neutzsky-Wulff, Anita V., Sauerberg, Per, Slaaby, Rita
Published in Nature (London) (24.10.2024)
Published in Nature (London) (24.10.2024)
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Journal Article
The counterregulatory response to hypoglycaemia in the pig
Gradel, Anna Katrina J., Kildegaard, Jonas, Ludvigsen, Trine P., Porsgaard, Trine, Schou‐Pedersen, Anne Marie V., Fels, Johannes J., Lykkesfeldt, Jens, Refsgaard, Hanne H. F.
Published in Basic & clinical pharmacology & toxicology (01.10.2020)
Published in Basic & clinical pharmacology & toxicology (01.10.2020)
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Journal Article
Molecular Representations in Machine-Learning-Based Prediction of PK Parameters for Insulin Analogs
Einarson, Kasper A., Bendtsen, Kristian M., Li, Kang, Thomsen, Maria, Kristensen, Niels R., Winther, Ole, Fulle, Simone, Clemmensen, Line, Refsgaard, Hanne H.F.
Published in ACS omega (04.07.2023)
Published in ACS omega (04.07.2023)
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Journal Article
Spatial distribution of soluble insulin in pig subcutaneous tissue: Effect of needle length, injection speed and injected volume
Thomsen, Maria, Rasmussen, Christian Hove, Refsgaard, Hanne H.F., Pedersen, Karen-Margrethe, Kirk, Rikke K., Poulsen, Mette, Feidenhans'l, Robert
Published in European journal of pharmaceutical sciences (15.11.2015)
Published in European journal of pharmaceutical sciences (15.11.2015)
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Journal Article
In silico modelling of permeation enhancement potency in Caco-2 monolayers based on molecular descriptors and random forest
Welling, Søren H., Clemmensen, Line K.H., Buckley, Stephen T., Hovgaard, Lars, Brockhoff, Per B., Refsgaard, Hanne H.F.
Published in European journal of pharmaceutics and biopharmaceutics (01.08.2015)
Published in European journal of pharmaceutics and biopharmaceutics (01.08.2015)
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Journal Article
Flavor Release Measurement by Atmospheric Pressure Chemical Ionization Ion Trap Mass Spectrometry, Construction of Interface and Mathematical Modeling of Release Profiles
Haahr, Anne-Mette, Madsen, Henrik, Smedsgaard, Jørn, Bredie, Wender L. P, Stahnke, Louise H, Refsgaard, Hanne H. F
Published in Analytical chemistry (Washington) (01.02.2003)
Published in Analytical chemistry (Washington) (01.02.2003)
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Journal Article
Increase of Neuronal Histamine in Obese Rats Is Associated with Decreases in Body Weight and Plasma Triglycerides
Malmlöf, Kjell, Golozoubova, Valeria, Peschke, Bernd, Wulff, Birgitte S, Refsgaard, Hanne H.F, Johansen, Peter B, Cremers, Thomas, Rimvall, Karin
Published in Obesity (Silver Spring, Md.) (01.12.2006)
Published in Obesity (Silver Spring, Md.) (01.12.2006)
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Journal Article
In silico prediction of cytochrome P450 inhibitors
Refsgaard, Hanne H. F., Jensen, Berith F., Christensen, Inge Thøger, Hagen, Nina, Brockhoff, Per B.
Published in Drug development research (01.05.2006)
Published in Drug development research (01.05.2006)
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