Living GenoChemetics by hyphenating synthetic biology and synthetic chemistry in vivo
Sharma, Sunil V., Tong, Xiaoxue, Pubill-Ulldemolins, Cristina, Cartmell, Christopher, Bogosyan, Emma J. A., Rackham, Emma J., Marelli, Enrico, Hamed, Refaat B., Goss, Rebecca J. M.
Published in Nature communications (09.08.2017)
Published in Nature communications (09.08.2017)
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Journal Article
The enzymes of β-lactam biosynthesis
Hamed, Refaat B, Gomez-Castellanos, J. Ruben, Henry, Luc, Ducho, Christian, McDonough, Michael A, Schofield, Christopher J
Published in Natural product reports (01.01.2013)
Published in Natural product reports (01.01.2013)
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Journal Article
Iron-Mediated Cleavage of C----C Bonds in Vicinal Tricarbonyl Compounds in Water
Mecinović, Jasmin, Hamed, Refaat B, Schofield, Christopher J
Published in Angewandte Chemie (International ed.) (30.03.2009)
Published in Angewandte Chemie (International ed.) (30.03.2009)
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Journal Article
A natural solution to photoprotection and isolation of the potent polyene antibiotic, marinomycin A
Bailey, Christopher S, Zarins-Tutt, Joseph S, Agbo, Matthias, Gao, Hong, Diego-Taboada, Alberto, Gan, Maoluo, Hamed, Refaat B, Abraham, Emily R, Mackenzie, Grahame, Evans, P. Andrew, Goss, Rebecca J. M
Published in Chemical science (Cambridge) (28.08.2019)
Published in Chemical science (Cambridge) (28.08.2019)
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Journal Article
Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans
Ge, Wei, Wolf, Alexander, Feng, Tianshu, Ho, Chia-hua, Sekirnik, Rok, Zayer, Adam, Granatino, Nicolas, Cockman, Matthew E, Loenarz, Christoph, Loik, Nikita D, Hardy, Adam P, Claridge, Timothy D W, Hamed, Refaat B, Chowdhury, Rasheduzzaman, Gong, Lingzhi, Robinson, Carol V, Trudgian, David C, Jiang, Miao, Mackeen, Mukram M, Mccullagh, James S, Gordiyenko, Yuliya, Thalhammer, Armin, Yamamoto, Atsushi, Yang, Ming, Liu-Yi, Phebee, Zhang, Zhihong, Schmidt-Zachmann, Marion, Kessler, Benedikt M, Ratcliffe, Peter J, Preston, Gail M, Coleman, Mathew L, Schofield, Christopher J
Published in Nature chemical biology (01.12.2012)
Published in Nature chemical biology (01.12.2012)
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Journal Article
Crotonases: Nature’s Exceedingly Convertible Catalysts
Lohans, Christopher T, Wang, David Y, Wang, Jimmy, Hamed, Refaat B, Schofield, Christopher J
Published in ACS catalysis (06.10.2017)
Published in ACS catalysis (06.10.2017)
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Journal Article
Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains
Yang, Ming, Chowdhury, Rasheduzzaman, Ge, Wei, Hamed, Refaat B, McDonough, Michael A, Claridge, Timothy D.W, Kessler, Benedikt M, Cockman, Matthew E, Ratcliffe, Peter J, Schofield, Christopher J
Published in The FEBS journal (01.04.2011)
Published in The FEBS journal (01.04.2011)
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Journal Article
The expression of MUC1 in human Fallopian tube during the menstrual cycle and in ectopic pregnancy
Al-Azemi, M., Refaat, B., Aplin, J., Ledger, W.
Published in Human reproduction (Oxford) (01.10.2009)
Published in Human reproduction (Oxford) (01.10.2009)
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Journal Article
Biocatalytic production of bicyclic β-lactams with three contiguous chiral centres using engineered crotonases
Hamed, Refaat B., Gomez-Castellanos, J. Ruben, Henry, Luc, Warhaut, Sven, Claridge, Timothy D. W., Schofield, Christopher J.
Published in Communications chemistry (24.01.2019)
Published in Communications chemistry (24.01.2019)
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Journal Article
Monitoring the Activity of 2-Oxoglutarate Dependent Histone Demethylases by NMR Spectroscopy: Direct Observation of Formaldehyde
Hopkinson, Richard J, Hamed, Refaat B, Rose, Nathan R, Claridge, Timothy D.W, Schofield, Christopher J
Published in Chembiochem : a European journal of chemical biology (01.03.2010)
Published in Chembiochem : a European journal of chemical biology (01.03.2010)
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Journal Article
Use of Methylmalonyl-CoA Epimerase in Enhancing Crotonase Stereoselectivity
Hamed, Refaat B., Gomez-Castellanos, J. Ruben, Sean Froese, D., Krysztofinska, Ewelina, Yue, Wyatt W., Schofield, Christopher J.
Published in Chembiochem : a European journal of chemical biology (15.03.2016)
Published in Chembiochem : a European journal of chemical biology (15.03.2016)
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Journal Article
Stereoselective C–C bond formation catalysed by engineered carboxymethylproline synthases
Hamed, Refaat B., Gomez-Castellanos, J. Ruben, Thalhammer, Armin, Harding, Daniel, Ducho, Christian, Claridge, Timothy D. W., Schofield, Christopher J.
Published in Nature chemistry (01.05.2011)
Published in Nature chemistry (01.05.2011)
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Journal Article
Crotonase Catalysis Enables Flexible Production of Functionalized Prolines and Carbapenams
Hamed, Refaat B, Henry, Luc, Gomez-Castellanos, J. Ruben, Mecinović, Jasmin, Ducho, Christian, Sorensen, John L, Claridge, Timothy D. W, Schofield, Christopher J
Published in Journal of the American Chemical Society (11.01.2012)
Published in Journal of the American Chemical Society (11.01.2012)
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