Use of the γ-H2AX assay to monitor DNA damage and repair in translational cancer research
Ivashkevich, Alesia, Redon, Christophe E, Nakamura, Asako J, Martin, Roger F, Martin, Olga A
Published in Cancer letters (31.12.2012)
Published in Cancer letters (31.12.2012)
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Journal Article
Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assay
Ji, Jiuping, Zhang, Yiping, Redon, Christophe E, Reinhold, William C, Chen, Alice P, Fogli, Laura K, Holbeck, Susan L, Parchment, Ralph E, Hollingshead, Melinda, Tomaszewski, Joseph E, Dudon, Quentin, Pommier, Yves, Doroshow, James H, Bonner, William M
Published in PloS one (03.02.2017)
Published in PloS one (03.02.2017)
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Journal Article
SLFN11 Blocks Stressed Replication Forks Independently of ATR
Murai, Junko, Tang, Sai-Wen, Leo, Elisabetta, Baechler, Simone A., Redon, Christophe E., Zhang, Hongliang, Al Abo, Muthana, Rajapakse, Vinodh N., Nakamura, Eijiro, Jenkins, Lisa M. Miller, Aladjem, Mirit I., Pommier, Yves
Published in Molecular cell (01.02.2018)
Published in Molecular cell (01.02.2018)
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Journal Article
Regulation of cell cycle drivers by Cullin-RING ubiquitin ligases
Jang, Sang-Min, Redon, Christophe E, Thakur, Bhushan L, Bahta, Meriam K, Aladjem, Mirit I
Published in Experimental & molecular medicine (01.10.2020)
Published in Experimental & molecular medicine (01.10.2020)
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Journal Article
Mitochondrial topoisomerase I is critical for mitochondrial integrity and cellular energy metabolism
Douarre, Céline, Sourbier, Carole, Dalla Rosa, Ilaria, Brata Das, Benu, Redon, Christophe E, Zhang, Hongliang, Neckers, Len, Pommier, Yves
Published in PloS one (20.07.2012)
Published in PloS one (20.07.2012)
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Journal Article
BRCA2 associates with MCM10 to suppress PRIMPOL-mediated repriming and single-stranded gap formation after DNA damage
Kang, Zhihua, Fu, Pan, Alcivar, Allen L, Fu, Haiqing, Redon, Christophe, Foo, Tzeh Keong, Zuo, Yamei, Ye, Caiyong, Baxley, Ryan, Madireddy, Advaitha, Buisson, Remi, Bielinsky, Anja-Katrin, Zou, Lee, Shen, Zhiyuan, Aladjem, Mirit I, Xia, Bing
Published in Nature communications (13.10.2021)
Published in Nature communications (13.10.2021)
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Journal Article
γH2AX and cancer
Bonner, William M, Redon, Christophe E, Dickey, Jennifer S, Nakamura, Asako J, Sedelnikova, Olga A, Solier, Stéphanie, Pommier, Yves
Published in Nature reviews. Cancer (01.12.2008)
Published in Nature reviews. Cancer (01.12.2008)
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Journal Article
Preventing excess replication origin activation to ensure genome stability
Thakur, Bhushan L., Ray, Anagh, Redon, Christophe E., Aladjem, Mirit I.
Published in Trends in genetics (01.02.2022)
Published in Trends in genetics (01.02.2022)
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Histone variant H2A.J accumulates in senescent cells and promotes inflammatory gene expression
Contrepois, Kévin, Coudereau, Clément, Benayoun, Bérénice A, Schuler, Nadine, Roux, Pierre-François, Bischof, Oliver, Courbeyrette, Régis, Carvalho, Cyril, Thuret, Jean-Yves, Ma, Zhihai, Derbois, Céline, Nevers, Marie-Claire, Volland, Hervé, Redon, Christophe E, Bonner, William M, Deleuze, Jean-François, Wiel, Clotilde, Bernard, David, Snyder, Michael P, Rübe, Claudia E, Olaso, Robert, Fenaille, François, Mann, Carl
Published in Nature communications (10.05.2017)
Published in Nature communications (10.05.2017)
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Journal Article
Dual Roles of Poly(dA:dT) Tracts in Replication Initiation and Fork Collapse
Tubbs, Anthony, Sridharan, Sriram, van Wietmarschen, Niek, Maman, Yaakov, Callen, Elsa, Stanlie, Andre, Wu, Wei, Wu, Xia, Day, Amanda, Wong, Nancy, Yin, Mianmian, Canela, Andres, Fu, Haiqing, Redon, Christophe, Pruitt, Steven C., Jaszczyszyn, Yan, Aladjem, Mirit I., Aplan, Peter D., Hyrien, Olivier, Nussenzweig, André
Published in Cell (23.08.2018)
Published in Cell (23.08.2018)
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Journal Article
Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress
Thomas, Anish, Takahashi, Nobuyuki, Rajapakse, Vinodh N, Zhang, Xiaohu, Sun, Yilun, Ceribelli, Michele, Wilson, Kelli M, Zhang, Yang, Beck, Erin, Sciuto, Linda, Nichols, Samantha, Elenbaas, Brian, Puc, Janusz, Dahmen, Heike, Zimmermann, Astrid, Varonin, Jillian, Schultz, Christopher W, Kim, Sehyun, Shimellis, Hirity, Desai, Parth, Klumpp-Thomas, Carleen, Chen, Lu, Travers, Jameson, McKnight, Crystal, Michael, Sam, Itkin, Zina, Lee, Sunmin, Yuno, Akira, Lee, Min-Jung, Redon, Christophe E, Kindrick, Jessica D, Peer, Cody J, Wei, Jun S, Aladjem, Mirit I, Figg, William Douglas, Steinberg, Seth M, Trepel, Jane B, Zenke, Frank T, Pommier, Yves, Khan, Javed, Thomas, Craig J
Published in Cancer cell (12.04.2021)
Published in Cancer cell (12.04.2021)
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Journal Article
Role of oxidatively induced DNA lesions in human pathogenesis
Sedelnikova, Olga A., Redon, Christophe E., Dickey, Jennifer S., Nakamura, Asako J., Georgakilas, Alexandros G., Bonner, William M.
Published in Mutation research (01.04.2010)
Published in Mutation research (01.04.2010)
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Journal Article
Conference Proceeding
Phase I Study of ATR Inhibitor M6620 in Combination With Topotecan in Patients With Advanced Solid Tumors
Thomas, Anish, Redon, Christophe E, Sciuto, Linda, Padiernos, Emerson, Ji, Jiuping, Lee, Min-Jung, Yuno, Akira, Lee, Sunmin, Zhang, Yiping, Tran, Lan, Yutzy, William, Rajan, Arun, Guha, Udayan, Chen, Haobin, Hassan, Raffit, Alewine, Christine C, Szabo, Eva, Bates, Susan E, Kinders, Robert J, Steinberg, Seth M, Doroshow, James H, Aladjem, Mirit I, Trepel, Jane B, Pommier, Yves
Published in Journal of clinical oncology (01.06.2018)
Published in Journal of clinical oncology (01.06.2018)
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Journal Article
Mito-tempol and dexrazoxane exhibit cardioprotective and chemotherapeutic effects through specific protein oxidation and autophagy in a syngeneic breast tumor preclinical model
Dickey, Jennifer S, Gonzalez, Yanira, Aryal, Baikuntha, Mog, Steven, Nakamura, Asako J, Redon, Christophe E, Baxa, Ulrich, Rosen, Elliot, Cheng, Gang, Zielonka, Jacek, Parekh, Palak, Mason, Karen P, Joseph, Joy, Kalyanaraman, Balaraman, Bonner, William, Herman, Eugene, Shacter, Emily, Rao, V Ashutosh
Published in PloS one (05.08.2013)
Published in PloS one (05.08.2013)
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Journal Article
Convergence of SIRT1 and ATR signaling to modulate replication origin dormancy
Thakur, Bhushan L, Baris, Adrian M, Fu, Haiqing, Redon, Christophe E, Pongor, Lorinc S, Mosavarpour, Sara, Gross, Jacob M, Jang, Sang-Min, Sebastian, Robin, Utani, Koichi, Jenkins, Lisa M, Indig, Fred E, Aladjem, Mirit I
Published in Nucleic acids research (20.05.2022)
Published in Nucleic acids research (20.05.2022)
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