Inhibition of the mammalian target of rapamycin (mTOR) in advanced pancreatic cancer: results of two phase II studies
Javle, Milind M, Shroff, Rachna T, Xiong, Henry, Varadhachary, Gauri A, Fogelman, David, Reddy, Shrikanth A, Davis, Darren, Zhang, Yujian, Wolff, Robert A, Abbruzzese, James L
Published in BMC cancer (14.07.2010)
Published in BMC cancer (14.07.2010)
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The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-κB and c-Myc in pancreatic cancer cells
ASANO, Takayuki, YIXIN YAO, JIJIANG ZHU, DONGHUI LI, ABBRUZZESE, James L, REDDY, Shrikanth A. G
Published in Oncogene (11.11.2004)
Published in Oncogene (11.11.2004)
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PTEN down regulates AP-1 and targets c-fos in human glioma cells Via PI3-kinase/Akt pathway
Koul, Dimpy, Shen, Ruijun, Shishodia, Shishir, Takada, Yasanuri, Bhat, Krishna P, Reddy, Shrikanth A. G, Aggarwal, Bharat B, Yung, W. K. Alfred
Published in Molecular and cellular biochemistry (01.06.2007)
Published in Molecular and cellular biochemistry (01.06.2007)
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Insulin receptor substrate is a mediator of phosphoinositide 3-kinase activation in quiescent pancreatic cancer cells
ASANO, Takayuki, YIXIN YAO, SHIN, Sonyo, MCCUBREY, James, ABBRUZZESE, James L, REDDY, Shrikanth A. G
Published in Cancer research (Chicago, Ill.) (15.10.2005)
Published in Cancer research (Chicago, Ill.) (15.10.2005)
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Tocotrienols inhibit AKT and ERK activation and suppress pancreatic cancer cell proliferation by suppressing the ErbB2 pathway
Shin-Kang, Sonyo, Ramsauer, Victoria P., Lightner, Janet, Chakraborty, Kanishka, Stone, William, Campbell, Sharon, Reddy, Shrikanth A.G., Krishnan, Koyamangalath
Published in Free radical biology & medicine (15.09.2011)
Published in Free radical biology & medicine (15.09.2011)
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Constitutive activation of AKT pathway inhibits TNF-induced apoptosis in mitochondrial DNA-deficient human myelogenous leukemia ML-1a
Suzuki, Seigo, Naito, Akihiro, Asano, Takayuki, Evans, Teresa T, Reddy, Shrikanth A.G, Higuchi, Masahiro
Published in Cancer letters (08.09.2008)
Published in Cancer letters (08.09.2008)
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BSTA promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiation
Yao, Yixin, Suraokar, Milind, Darnay, Bryant G, Hollier, Brett G, Shaiken, Tattym E, Asano, Takayuki, Chen, Chien-Hung, Chang, Benny H-J, Lu, Yiling, Mills, Gordon B, Sarbassov, Dos, Mani, Sendurai A, Abbruzzese, James L, Reddy, Shrikanth A G
Published in Science signaling (08.01.2013)
Published in Science signaling (08.01.2013)
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536 Oncogenic Ki-RAS-miR-21 Signaling Promotes AKT Activation in Pancreatic Cancer Cells Through a Novel AKT-Interacting Protein Bsta
Yao, Yixin, Canizales, Martin, Ramachandran, Vijaya, Arumugam, Thiruvengadam, Logsdon, Craig D, Abbruzzese, James, Guha, Sushovan, Reddy, Shrikanth A
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
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Activator Protein-1 Has an Essential Role in Pancreatic Cancer Cells and Is Regulated by a Novel Akt-Mediated Mechanism
Shin, Sonyo, Asano, Takayuki, Yao, Yixin, Zhang, Ronghua, Claret, Francois-Xavier, Korc, Murray, Sabapathy, Kanaga, Menter, David G, Abbruzzese, James L, Reddy, Shrikanth A G
Published in Molecular cancer research (01.05.2009)
Published in Molecular cancer research (01.05.2009)
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Resistance of Human Ovarian Cancer Cells to Tumor Necrosis Factor α Is a Consequence of Nuclear Factor κB-Mediated Induction of Fas-Associated Death Domain-Like Interleukin-1β-Converting Enzyme-Like Inhibitory Protein
Xiao, Chao Wu, Yan, Xiaojuan, Li, Yulian, Reddy, Shrikanth A. G, Tsang, Benjamin K
Published in Endocrinology (Philadelphia) (01.02.2003)
Published in Endocrinology (Philadelphia) (01.02.2003)
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Hypothesis generation in signaling networks
Ruths, Derek A, Nakhleh, Luay, Iyengar, M Sriram, Reddy, Shrikanth A G, Ram, Prahlad T
Published in Journal of computational biology (01.11.2006)
Published in Journal of computational biology (01.11.2006)
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Erratum: The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-κB and c-Myc in pancreatic cancer cells
Asano, Takayuki, Yao, Yixin, Zhu, Jijiang, Li, Donghui, Abbruzzese, James L, Reddy, Shrikanth AG
Published in Oncogene (16.06.2005)
Published in Oncogene (16.06.2005)
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Alleviating the Suppression of Glycogen Synthase Kinase-3β by Akt Leads to the Phosphorylation of cAMP-response Element-binding Protein and Its Transactivation in Intact Cell Nuclei
Salas, Thomas R., Reddy, Shrikanth A., Clifford, John L., Davis, Roger J., Kikuchi, Akira, Lippman, Scott M., Menter, David G.
Published in The Journal of biological chemistry (17.10.2003)
Published in The Journal of biological chemistry (17.10.2003)
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Inhibition of the mammalian target of rapamycin
Javle, Milind M, Varadhachary, Gauri A, Xiong, Henry, Shroff, Rachna T, Zhang, Yujian, Wolff, Robert A, Davis, Darren, Reddy, Shrikanth A, Fogelman, David, Abbruzzese, James L
Published in BMC cancer (14.07.2010)
Published in BMC cancer (14.07.2010)
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Journal Article
The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-kappaB and c-Myc in pancreatic cancer cells
Asano, Takayuki, Yao, Yixin, Zhu, Jijiang, Li, Donghui, Abbruzzese, James L, Reddy, Shrikanth A G
Published in Oncogene (11.11.2004)
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Published in Oncogene (11.11.2004)
Journal Article
The PI 3-kinase Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF- B and c-Myc in pancreatic cancer cells
Asano, Takayuki, Yao, Yixin, Zhu, Jijiang, Li, Donghui, Abbruzzese, James L, Reddy, Shrikanth A G
Published in Oncogene (11.11.2004)
Published in Oncogene (11.11.2004)
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