ASN004, A 5T4-targeting scFv-Fc Antibody-Drug Conjugate with High Drug-to-Antibody Ratio, Induces Complete and Durable Tumor Regressions in Preclinical Models
Smith, Roger A, Zammit, David J, Damle, Nitin K, Usansky, Helen, Reddy, Sanjeeva P, Lin, Jun-Hsiang, Mistry, Mahesh, Rao, Niranjan S, Denis, Louis J, Gupta, Sandeep
Published in Molecular cancer therapeutics (01.08.2021)
Published in Molecular cancer therapeutics (01.08.2021)
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Journal Article
The Epithelium-specific ETS Protein EHF/ESE-3 Is a Context-dependent Transcriptional Repressor Downstream of MAPK Signaling Cascades
Tugores, Antonio, Le, Jennifer, Sorokina, Irina, Snijders, A.J., Duyao, Mabel, Reddy, P. Sanjeeva, Carlée, Leone, Ronshaugen, Mathew, Mushegian, Arcady, Watanaskul, Tim, Chu, Sunny, Buckler, Alan, Emtage, Spencer, McCormick, Mary Kay
Published in The Journal of biological chemistry (08.06.2001)
Published in The Journal of biological chemistry (08.06.2001)
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Journal Article
ERK1 ERK2 HETEROCYCLIC INHIBITORS OF ERK1 AND ERK2 AND THEIR USE IN THE TREATMENT OF CANCER
THOMPSON SCOTT K, HALLUR GURULINGAPPA, MULLANGI RAMESH, SMITH ROGER A, ZAINUDDIN MOHD, MULAKALA CHANDRIKA, DEWANG PURUSHOTTAM M, KETHIRI RAGHAVA REDDY, VENKATESAN ARANAPAKAM M, REDDY SANJEEVA P
Year of Publication 02.03.2021
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Year of Publication 02.03.2021
Patent
ERK1 및 ERK2의 헤테로사이클릭 억제제 및 암 치료에서 이의 용도
THOMPSON SCOTT K, HALLUR GURULINGAPPA, MULLANGI RAMESH, SMITH ROGER A, ZAINUDDIN MOHD, MULAKALA CHANDRIKA, DEWANG PURUSHOTTAM M, KETHIRI RAGHAVA REDDY, VENKATESAN ARANAPAKAM M, REDDY SANJEEVA P
Year of Publication 09.02.2018
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Year of Publication 09.02.2018
Patent
Abstract B05: ASN007, an oral ERK1/2 inhibitor, shows strong antitumor activity across a panel of KRAS subtype mutant cancer models
Reddy, Sanjeeva P., Thompson, Scott K., Usansky, Helen, Smith, Roger A., Denis, Louis, Gupta, Sandeeep
Published in Molecular cancer research (01.05.2020)
Published in Molecular cancer research (01.05.2020)
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Journal Article
Abstract 5783: Strong antitumor activity of ASN007, an oral ERK1/2 inhibitor, in PDX tumor models with MAP kinase pathway alterations including KRAS mutations
Reddy, Sanjeeva P., Rao, Niranjan S., Smith, Roger A., Thompson, Scott K., Toker, Sarper
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract B150: ASN007, a novel oral ERK inhibitor, shows robust antitumor activity in RAS mutant cancer models
Reddy, Sanjeeva P., Sivanandhan, Dhanalakshmi, Dewang, Purushottam, Rao, Niranjan, Smith, Roger A., Thompson, Scott K.
Published in Molecular cancer therapeutics (01.01.2018)
Published in Molecular cancer therapeutics (01.01.2018)
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Journal Article
Abstract 4204: ASN002: A novel dual SYK/JAK inhibitor with strong antitumor activity in both hematological and solid tumor xenograft models
Reddy, Sanjeeva P., Rao, Niranjan, Zammit, David, Thompson, Scott K., Smith, Roger A., Denis, Louis
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 158: ASN003, a highly selective inhibitor of B-Raf and PI3 kinases, shows strong antitumor activity in B-Raf inhibitor resistant patient-derived xenograft models
Thompson, Scott K., Smith, Roger A., Rao, Niranjan, Wick, Michael J., Reddy, Sanjeeva P.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 187: ASN0007, a potent ERK12 inhibitor with strong antitumor activity in multiple RAS mutant models
Reddy, Sanjeeva P, Sivanandhan, Dhanalakshmi, Kethiri, Raghava Reddy, Nair, Sreekala, Dewang, Purushottam, Zainuddin, Mohd, Vaithilingam, Krishnakumar, Smith, Roger A, Gupta, Sandeep, Thompson, Scott K
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Abstract 187: ASN0007, a potent ERK1/2 inhibitor with strong antitumor activity in multiple RAS mutant models
Reddy, Sanjeeva P., Sivanandhan, Dhanalakshmi, Kethiri, Raghava Reddy, Nair, Sreekala, Dewang, Purushottam, Zainuddin, Mohd, Vaithilingam, Krishnakumar, Smith, Roger A., Gupta, Sandeep, Thompson, Scott K.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Abstract B100: ASN003, a unique B-RAF inhibitor with additional selective activity against PI3K and mTOR kinases, shows strong antitumor activity in multiple xenograft models
Thompson, Scott K., Jaleel, Mahaboobi, Nyavanandi, Vijay Kumar, Ramachandra, Murali, Subramanya, Hosahalli, Basavaraju, Aravind, Sihorkar, Vaibhav, Smith, Roger A., Rao, Niranjan, Gupta, Sandeep, Reddy, Sanjeeva P.
Published in Molecular cancer therapeutics (01.12.2015)
Published in Molecular cancer therapeutics (01.12.2015)
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Journal Article
Abstract 1693: ASN004, a novel 5T4-targeted Dolaflexin™ antibody drug conjugate, causes complete regression in multiple solid tumor models
Smith, Roger A., Damle, Nitin K., Reddy, Sanjeeva P., Yurkovetskiy, Alex, Bodyak, Natalya, Yin, Mao, Gumerov, Dmitry, Ter-Ovanesyan, Elena, Qin, Liu, Park, Peter U., Lowinger, Timothy B., Gupta, Sandeep
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Abstract B274: Discovery and characterization of a highly selective inhibitor of B-RAF, PI3K, and mTOR kinases with antitumor activity in B-RAF and B-RAF/PI3K pathway double mutant xenograft models
Reddy, Sanjeeva P., Jaleel, Mahaboobi, Nyavanandi, Vijay K., Ramachandra, Murali, Subramanya, Hosahalli, Basavaraju, Aravind, Sihorkar, Vaibhav, Smith, Roger A., Gupta, Sandeep, Thompson, Scott K.
Published in Molecular cancer therapeutics (01.11.2013)
Published in Molecular cancer therapeutics (01.11.2013)
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Journal Article
Isolation and Characterization of a Near-Haploid Human Cell Line
Kotecki, Maciej, Reddy, P.Sanjeeva, Cochran, Brent H.
Published in Experimental cell research (01.11.1999)
Published in Experimental cell research (01.11.1999)
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