Immunotherapy of cytomegalovirus infection by low-dose adoptive transfer of antiviral CD8 T cells relies on substantial post-transfer expansion of central memory cells but not effector-memory cells
Holtappels, Rafaela, Becker, Sara, Hamdan, Sara, Freitag, Kirsten, Podlech, Jürgen, Lemmermann, Niels A, Reddehase, Matthias J
Published in PLoS pathogens (16.11.2023)
Published in PLoS pathogens (16.11.2023)
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Cytomegalovirus inhibitors of programmed cell death restrict antigen cross-presentation in the priming of antiviral CD8 T cells
Ebert, Stefan, Böhm, Verena, Büttner, Julia K, Brune, Wolfram, Brinkmann, Melanie M, Holtappels, Rafaela, Reddehase, Matthias J, Lemmermann, Niels A. W
Published in PLoS pathogens (15.08.2024)
Published in PLoS pathogens (15.08.2024)
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Journal Article
Modulation of cytomegalovirus immune evasion identifies direct antigen presentation as the predominant mode of CD8 T-cell priming during immune reconstitution after hematopoietic cell transplantation
Holtappels, Rafaela, Büttner, Julia K, Freitag, Kirsten, Reddehase, Matthias J, Lemmermann, Niels A
Published in Frontiers in immunology (15.02.2024)
Published in Frontiers in immunology (15.02.2024)
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IL-33/ST2 pathway drives regulatory T cell dependent suppression of liver damage upon cytomegalovirus infection
Popovic, Branka, Golemac, Mijo, Podlech, Jürgen, Zeleznjak, Jelena, Bilic-Zulle, Lidija, Lukic, Miodrag L, Cicin-Sain, Luka, Reddehase, Matthias J, Sparwasser, Tim, Krmpotic, Astrid, Jonjic, Stipan
Published in PLoS pathogens (01.04.2017)
Published in PLoS pathogens (01.04.2017)
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Stochastic Episodes of Latent Cytomegalovirus Transcription Drive CD8 T-Cell "Memory Inflation" and Avoid Immune Evasion
Griessl, Marion, Renzaho, Angelique, Freitag, Kirsten, Seckert, Christof K, Reddehase, Matthias J, Lemmermann, Niels A W
Published in Frontiers in immunology (22.04.2021)
Published in Frontiers in immunology (22.04.2021)
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Journal Article
Host-Adapted Gene Families Involved in Murine Cytomegalovirus Immune Evasion
Becker, Sara, Fink, Annette, Podlech, Jürgen, Reddehase, Matthias J, Lemmermann, Niels A
Published in Viruses (11.01.2022)
Published in Viruses (11.01.2022)
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Journal Article
Direct antigen presentation is the canonical pathway of cytomegalovirus CD8 T-cell priming regulated by balanced immune evasion ensuring a strong antiviral response
Büttner, Julia K, Becker, Sara, Fink, Annette, Brinkmann, Melanie M, Holtappels, Rafaela, Reddehase, Matthias J, Lemmermann, Niels A
Published in Frontiers in immunology (12.12.2023)
Published in Frontiers in immunology (12.12.2023)
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Journal Article
Memory CD8 T Cells Protect against Cytomegalovirus Disease by Formation of Nodular Inflammatory Foci Preventing Intra-Tissue Virus Spread
Holtappels, Rafaela, Podlech, Jürgen, Freitag, Kirsten, Lemmermann, Niels A., Reddehase, Matthias J.
Published in Viruses (25.05.2022)
Published in Viruses (25.05.2022)
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Coincident airway exposure to low-potency allergen and cytomegalovirus sensitizes for allergic airway disease by viral activation of migratory dendritic cells
Reuter, Sebastian, Lemmermann, Niels A W, Maxeiner, Joachim, Podlech, Jürgen, Beckert, Hendrik, Freitag, Kirsten, Teschner, Daniel, Ries, Frederic, Taube, Christian, Buhl, Roland, Reddehase, Matthias J, Holtappels, Rafaela
Published in PLoS pathogens (01.03.2019)
Published in PLoS pathogens (01.03.2019)
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Peptide Processing Is Critical for T-Cell Memory Inflation and May Be Optimized to Improve Immune Protection by CMV-Based Vaccine Vectors
Dekhtiarenko, Iryna, Ratts, Robert B, Blatnik, Renata, Lee, Lian N, Fischer, Sonja, Borkner, Lisa, Oduro, Jennifer D, Marandu, Thomas F, Hoppe, Stephanie, Ruzsics, Zsolt, Sonnemann, Julia K, Mansouri, Mandana, Meyer, Christine, Lemmermann, Niels A W, Holtappels, Rafaela, Arens, Ramon, Klenerman, Paul, Früh, Klaus, Reddehase, Matthias J, Riemer, Angelika B, Cicin-Sain, Luka
Published in PLoS pathogens (15.12.2016)
Published in PLoS pathogens (15.12.2016)
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Non-redundant and redundant roles of cytomegalovirus gH/gL complexes in host organ entry and intra-tissue spread
Lemmermann, Niels A W, Krmpotic, Astrid, Podlech, Jürgen, Brizic, Ilija, Prager, Adrian, Adler, Heiko, Karbach, Astrid, Wu, Yiquan, Jonjic, Stipan, Reddehase, Matthias J, Adler, Barbara
Published in PLoS pathogens (01.02.2015)
Published in PLoS pathogens (01.02.2015)
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The viral chemokine MCK-2 of murine cytomegalovirus promotes infection as part of a gH/gL/MCK-2 complex
Wagner, Felicia M, Brizic, Ilija, Prager, Adrian, Trsan, Tihana, Arapovic, Maja, Lemmermann, Niels A W, Podlech, Jürgen, Reddehase, Matthias J, Lemnitzer, Frederic, Bosse, Jens Bernhard, Gimpfl, Martina, Marcinowski, Lisa, MacDonald, Margaret, Adler, Heiko, Koszinowski, Ulrich H, Adler, Barbara
Published in PLoS pathogens (01.07.2013)
Published in PLoS pathogens (01.07.2013)
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The NK Cell Response to Mouse Cytomegalovirus Infection Affects the Level and Kinetics of the Early CD8+ T-Cell Response
MITROVIC, Maja, ARAPOVIC, Jurica, JORDAN, Stefan, FODIL-CORNU, Nassima, EBERT, Stefan, VIDAL, Silvia M, KRMPOTIC, Astrid, REDDEHASE, Matthias J, JONJIC, Stipan
Published in Journal of Virology (01.02.2012)
Published in Journal of Virology (01.02.2012)
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Therapeutic Vaccination of Hematopoietic Cell Transplantation Recipients Improves Protective CD8 T-Cell Immunotherapy of Cytomegalovirus Infection
Gergely, Kerstin M, Podlech, Jürgen, Becker, Sara, Freitag, Kirsten, Krauter, Steffi, Büscher, Nicole, Holtappels, Rafaela, Plachter, Bodo, Reddehase, Matthias J, Lemmermann, Niels A W
Published in Frontiers in immunology (19.08.2021)
Published in Frontiers in immunology (19.08.2021)
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Journal Article
Mast cells expedite control of pulmonary murine cytomegalovirus infection by enhancing the recruitment of protective CD8 T cells to the lungs
Ebert, Stefan, Becker, Marc, Lemmermann, Niels A W, Büttner, Julia K, Michel, Anastasija, Taube, Christian, Podlech, Jürgen, Böhm, Verena, Freitag, Kirsten, Thomas, Doris, Holtappels, Rafaela, Reddehase, Matthias J, Stassen, Michael
Published in PLoS pathogens (01.04.2014)
Published in PLoS pathogens (01.04.2014)
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Evaluating Human T-Cell Therapy of Cytomegalovirus Organ Disease in HLA-Transgenic Mice
Thomas, Simone, Klobuch, Sebastian, Podlech, Jürgen, Plachter, Bodo, Hoffmann, Petra, Renzaho, Angelique, Theobald, Matthias, Reddehase, Matthias J, Herr, Wolfgang, Lemmermann, Niels A W
Published in PLoS pathogens (01.07.2015)
Published in PLoS pathogens (01.07.2015)
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Journal Article
The murine cytomegalovirus M35 protein antagonizes type I IFN induction downstream of pattern recognition receptors by targeting NF-κB mediated transcription
Chan, Baca, Gonçalves Magalhães, Vladimir, Lemmermann, Niels A W, Juranić Lisnić, Vanda, Stempel, Markus, Bussey, Kendra A, Reimer, Elisa, Podlech, Jürgen, Lienenklaus, Stefan, Reddehase, Matthias J, Jonjić, Stipan, Brinkmann, Melanie M
Published in PLoS pathogens (01.05.2017)
Published in PLoS pathogens (01.05.2017)
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