Design and Construction of a Focused DNA-Encoded Library for Multivalent Chromatin Reader Proteins
Rectenwald, Justin M, Guduru, Shiva Krishna Reddy, Dang, Zhao, Collins, Leonard B, Liao, Yi-En, Norris-Drouin, Jacqueline L, Cholensky, Stephanie H, Kaufmann, Kyle W, Hammond, Scott M, Kireev, Dmitri B, Frye, Stephen V, Pearce, Kenneth H
Published in Molecules (Basel, Switzerland) (22.02.2020)
Published in Molecules (Basel, Switzerland) (22.02.2020)
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Journal Article
Discovery of hit compounds for methyl-lysine reader proteins from a target class DNA-encoded library
Shell, Devan J., Rectenwald, Justin M., Buttery, Peter H., Johnson, Rebecca L., Foley, Caroline A., Guduru, Shiva K.R., Uguen, Mélanie, Rubiano, Juanita Sanchez, Zhang, Xindi, Li, Fengling, Norris-Drouin, Jacqueline L., Axtman, Matthew, Brian Hardy, P., Vedadi, Masoud, Frye, Stephen V., James, Lindsey I., Pearce, Kenneth H.
Published in SLAS discovery (01.12.2022)
Published in SLAS discovery (01.12.2022)
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Journal Article
Discovery of Potent Peptidomimetic Antagonists for Heterochromatin Protein 1 Family Proteins
Lamb, Kelsey N, Dishman, Sarah N, Waybright, Jarod M, Engelberg, Isabelle A, Rectenwald, Justin M, Norris-Drouin, Jacqueline L, Cholensky, Stephanie H, Pearce, Kenneth H, James, Lindsey I, Frye, Stephen V
Published in ACS omega (11.01.2022)
Published in ACS omega (11.01.2022)
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Journal Article
Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader
Potjewyd, Frances, Turner, Anne-Marie W., Beri, Joshua, Rectenwald, Justin M., Norris-Drouin, Jacqueline L., Cholensky, Stephanie H., Margolis, David M., Pearce, Kenneth H., Herring, Laura E., James, Lindsey I.
Published in Cell chemical biology (16.01.2020)
Published in Cell chemical biology (16.01.2020)
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PROTAC Linkerology Leads to an Optimized Bivalent Chemical Degrader of Polycomb Repressive Complex 2 (PRC2) Components
Bashore, Frances M., Foley, Caroline A., Ong, Han Wee, Rectenwald, Justin M., Hanley, Ronan P., Norris-Drouin, Jacqueline L., Cholensky, Stephanie H., Mills, Christine A., Pearce, Kenneth H., Herring, Laura E., Kireev, Dmitri, Frye, Stephen V., James, Lindsey I.
Published in ACS chemical biology (17.03.2023)
Published in ACS chemical biology (17.03.2023)
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Reprogramming CBX8-PRC1 function with a positive allosteric modulator
Suh, Junghyun L., Bsteh, Daniel, Hart, Bryce, Si, Yibo, Weaver, Tyler M., Pribitzer, Carina, Lau, Roy, Soni, Shivani, Ogana, Heather, Rectenwald, Justin M., Norris, Jacqueline L., Cholensky, Stephanie H., Sagum, Cari, Umana, Jessica D., Li, Dongxu, Hardy, Brian, Bedford, Mark T., Mumenthaler, Shannon M., Lenz, Heinz-Josef, Kim, Yong-Mi, Wang, Gang Greg, Pearce, Ken H., James, Lindsey I., Kireev, Dmitri B., Musselman, Catherine A., Frye, Stephen V., Bell, Oliver
Published in Cell chemical biology (21.04.2022)
Published in Cell chemical biology (21.04.2022)
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A Peptidomimetic Ligand Targeting the Chromodomain of MPP8 Reveals HRP2’s Association with the HUSH Complex
Waybright, Jarod M, Clinkscales, Sarah E, Barnash, Kimberly D, Budziszewski, Gabrielle R, Rectenwald, Justin M, Chiarella, Anna M, Norris-Drouin, Jacqueline L, Cholensky, Stephanie H, Pearce, Kenneth H, Herring, Laura E, McGinty, Robert K, Hathaway, Nathaniel A, James, Lindsey I
Published in ACS chemical biology (17.09.2021)
Published in ACS chemical biology (17.09.2021)
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Journal Article
A General TR-FRET Assay Platform for High-Throughput Screening and Characterizing Inhibitors of Methyl-Lysine Reader Proteins
Rectenwald, Justin M., Hardy, P. Brian, Norris-Drouin, Jacqueline L., Cholensky, Stephanie H., James, Lindsey I., Frye, Stephen V., Pearce, Kenneth H.
Published in SLAS discovery (01.07.2019)
Published in SLAS discovery (01.07.2019)
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Potent and Selective SETDB1 Covalent Negative Allosteric Modulator Reduces Methyltransferase Activity in Cells
Uguen, Mélanie, Shell, Devan J, Silva, Madhushika, Deng, Yu, Li, Fengling, Szewczyk, Magdalena M, Yang, Ka, Zhao, Yani, Stashko, Michael A, Norris-Drouin, Jacqueline L, Waybright, Jarod M, Beldar, Serap, Rectenwald, Justin M, Mordant, Angie L, Webb, Thomas S, Herring, Laura E, Arrowsmith, Cheryl H, Ackloo, Suzanne, Gygi, Steven P, McGinty, Robert K, Barsyte-Lovejoy, Dalia, Liu, Pengda, Halabelian, Levon, James, Lindsey I, Pearce, Kenneth H, Frye, Stephen V
Published in bioRxiv (28.09.2024)
Published in bioRxiv (28.09.2024)
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REPROGRAMMING CBX8-PRC1 FUNCTION WITH A POSITIVE ALLOSTERIC MODULATOR
Suh, Junghyun L, Bsteh, Daniel, Si, Yibo, Hart, Bryce, Weaver, Tyler M, Pribitzer, Carina, Lau, Roy, Soni, Shivani, Ogana, Heather, Rectenwald, Justin M, Norris, Jacqueline L, Cholensky, Stephanie H, Sagum, Cari, Umana, Jessica D, Li, Dongxu, Hardy, Brian, Bedford, Mark T, Mumenthaler, Shannon M, Lenz, Heinz-Josef, Yong-Mi, Kim, Wang, Gang Greg, Pearce, Ken H, James, Lindsey I, Kireev, Dmitri B, Musselman, Catherine A, Frye, Stephen V, Bell, Oliver
Published in bioRxiv (23.02.2021)
Published in bioRxiv (23.02.2021)
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