The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets
Peacock, Thomas P., Goldhill, Daniel H., Zhou, Jie, Baillon, Laury, Frise, Rebecca, Swann, Olivia C., Kugathasan, Ruthiran, Penn, Rebecca, Brown, Jonathan C., Sanchez-David, Raul Y., Braga, Luca, Williamson, Maia Kavanagh, Hassard, Jack A., Staller, Ecco, Hanley, Brian, Osborn, Michael, Giacca, Mauro, Davidson, Andrew D., Matthews, David A., Barclay, Wendy S.
Published in Nature microbiology (01.07.2021)
Published in Nature microbiology (01.07.2021)
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Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults
Killingley, Ben, Mann, Alex J., Kalinova, Mariya, Boyers, Alison, Goonawardane, Niluka, Zhou, Jie, Lindsell, Kate, Hare, Samanjit S., Brown, Jonathan, Frise, Rebecca, Smith, Emma, Hopkins, Claire, Noulin, Nicolas, Löndt, Brandon, Wilkinson, Tom, Harden, Stephen, McShane, Helen, Baillet, Mark, Gilbert, Anthony, Jacobs, Michael, Charman, Christine, Mande, Priya, Nguyen-Van-Tam, Jonathan S., Semple, Malcolm G., Read, Robert C., Ferguson, Neil M., Openshaw, Peter J., Rapeport, Garth, Barclay, Wendy S., Catchpole, Andrew P., Chiu, Christopher
Published in Nature medicine (01.05.2022)
Published in Nature medicine (01.05.2022)
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An Influenza A virus can evolve to use human ANP32E through altering polymerase dimerization
Sheppard, Carol M., Goldhill, Daniel H., Swann, Olivia C., Staller, Ecco, Penn, Rebecca, Platt, Olivia K., Sukhova, Ksenia, Baillon, Laury, Frise, Rebecca, Peacock, Thomas P., Fodor, Ervin, Barclay, Wendy S.
Published in Nature communications (10.10.2023)
Published in Nature communications (10.10.2023)
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Characterising viable virus from air exhaled by H1N1 influenza-infected ferrets reveals the importance of haemagglutinin stability for airborne infectivity
Singanayagam, Anika, Zhou, Jie, Elderfield, Ruth A, Frise, Rebecca, Ashcroft, Jonathan, Galiano, Monica, Miah, Shahjahan, Nicolaou, Laura, Barclay, Wendy S
Published in PLoS pathogens (25.02.2020)
Published in PLoS pathogens (25.02.2020)
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Journal Article
Favipiravir-resistant influenza A virus shows potential for transmission
Goldhill, Daniel H, Yan, Ada, Frise, Rebecca, Zhou, Jie, Shelley, Jennifer, Gallego Cortés, Ana, Miah, Shahjahan, Akinbami, Omolola, Galiano, Monica, Zambon, Maria, Lackenby, Angie, Barclay, Wendy S
Published in PLoS pathogens (01.06.2021)
Published in PLoS pathogens (01.06.2021)
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Journal Article
Evaluating the fitness of PA/I38T-substituted influenza A viruses with reduced baloxavir susceptibility in a competitive mixtures ferret model
Lee, Leo Yy, Zhou, Jie, Koszalka, Paulina, Frise, Rebecca, Farrukee, Rubaiyea, Baba, Keiko, Miah, Shahjahan, Shishido, Takao, Galiano, Monica, Hashimoto, Takashi, Omoto, Shinya, Uehara, Takeki, Mifsud, Edin J, Collinson, Neil, Kuhlbusch, Klaus, Clinch, Barry, Wildum, Steffen, Barclay, Wendy S, Hurt, Aeron C
Published in PLoS pathogens (06.05.2021)
Published in PLoS pathogens (06.05.2021)
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Journal Article
Baloxavir treatment of ferrets infected with influenza A(H1N1)pdm09 virus reduces onward transmission
Lee, Leo Yi Yang, Zhou, Jie, Frise, Rebecca, Goldhill, Daniel H, Koszalka, Paulina, Mifsud, Edin J, Baba, Kaoru, Noda, Takahiro, Ando, Yoshinori, Sato, Kenji, Yuki, Aoe-Ishikawa, Shishido, Takao, Uehara, Takeki, Wildum, Steffen, Zwanziger, Elke, Collinson, Neil, Kuhlbusch, Klaus, Clinch, Barry, Hurt, Aeron C, Barclay, Wendy S
Published in PLoS pathogens (01.04.2020)
Published in PLoS pathogens (01.04.2020)
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RNAi-based small molecule repositioning reveals clinically approved urea-based kinase inhibitors as broadly active antivirals
Lesch, Markus, Luckner, Madlen, Meyer, Michael, Weege, Friderike, Gravenstein, Isabella, Raftery, Martin, Sieben, Christian, Martin-Sancho, Laura, Imai-Matsushima, Aki, Welke, Robert-William, Frise, Rebecca, Barclay, Wendy, Schönrich, Günther, Herrmann, Andreas, Meyer, Thomas F, Karlas, Alexander
Published in PLoS pathogens (01.03.2019)
Published in PLoS pathogens (01.03.2019)
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Internal genes of a highly pathogenic H5N1 influenza virus determine high viral replication in myeloid cells and severe outcome of infection in mice
Li, Hui, Bradley, Konrad C, Long, Jason S, Frise, Rebecca, Ashcroft, Jonathan W, Hartgroves, Lorian C, Shelton, Holly, Makris, Spyridon, Johansson, Cecilia, Cao, Bin, Barclay, Wendy S
Published in PLoS pathogens (01.01.2018)
Published in PLoS pathogens (01.01.2018)
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Evaluation of a human mucosal tissue explant model for SARS-CoV-2 replication
Gordhan, Bhavna Gowan, Herrera, Carolina, Pillay, Azure-Dee, Seiphetlo, Thabiso, Ealand, Christopher Shawn, Machowski, Edith, Singh, Natasha, Seatholo, Ntombexolo, Otwombe, Kennedy, Lebina, Limakatso, Frise, Rebecca, Scarlatti, Gabriella, Chiodi, Francesca, Martinson, Neil, Fox, Julie, Kana, Bavesh Davandra
Published in PloS one (28.09.2023)
Published in PloS one (28.09.2023)
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Journal Article
Contact transmission of influenza virus between ferrets imposes a looser bottleneck than respiratory droplet transmission allowing propagation of antiviral resistance
Frise, Rebecca, Bradley, Konrad, van Doremalen, Neeltje, Galiano, Monica, Elderfield, Ruth A., Stilwell, Peter, Ashcroft, Jonathan W., Fernandez-Alonso, Mirian, Miah, Shahjahan, Lackenby, Angie, Roberts, Kim L., Donnelly, Christl A., Barclay, Wendy S.
Published in Scientific reports (19.07.2016)
Published in Scientific reports (19.07.2016)
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Species difference in ANP32A underlies influenza A virus polymerase host restriction
Long, Jason S., Giotis, Efstathios S., Moncorgé, Olivier, Frise, Rebecca, Mistry, Bhakti, James, Joe, Morisson, Mireille, Iqbal, Munir, Vignal, Alain, Skinner, Michael A., Barclay, Wendy S.
Published in Nature (London) (07.01.2016)
Published in Nature (London) (07.01.2016)
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Journal Article
Clinical and laboratory evaluation of SARS-CoV-2 lateral flow assays for use in a national COVID-19 seroprevalence survey
Flower, Barnaby, Brown, Jonathan C, Simmons, Bryony, Moshe, Maya, Frise, Rebecca, Penn, Rebecca, Kugathasan, Ruthiran, Petersen, Claire, Daunt, Anna, Ashby, Deborah, Riley, Steven, Atchison, Christina Joanne, Taylor, Graham P, Satkunarajah, Sutha, Naar, Lenny, Klaber, Robert, Badhan, Anjna, Rosadas, Carolina, Khan, Maryam, Fernandez, Natalia, Sureda-Vives, Macià, Cheeseman, Hannah M, O'Hara, Jessica, Fontana, Gianluca, Pallett, Scott J C, Rayment, Michael, Jones, Rachael, Moore, Luke S P, McClure, Myra O, Cherepanov, Peter, Tedder, Richard, Ashrafian, Hutan, Shattock, Robin, Ward, Helen, Darzi, Ara, Elliot, Paul, Barclay, Wendy S, Cooke, Graham S
Published in Thorax (01.12.2020)
Published in Thorax (01.12.2020)
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Levels of Influenza A Virus Defective Viral Genomes Determine Pathogenesis in the BALB/c Mouse Model
Penn, Rebecca, Tregoning, John S, Flight, Katie E, Baillon, Laury, Frise, Rebecca, Goldhill, Daniel H, Johansson, Cecilia, Barclay, Wendy S
Published in Journal of virology (09.11.2022)
Published in Journal of virology (09.11.2022)
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Journal Article
Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge
Killingley, Ben, Mann, Alex, Kalinova, Mariya, Boyers, Alison, Goonawardane, Niluka, Zhou, Jie, Lindsell, Kate, Hare, Samanjit S, Brown, Jonathan, Frise, Rebecca, Smith, Emma, Hopkins, Claire, Noulin, Nicolas, Londt, Brandon, Wilkinson, Tom, Harden, Stephen, McShane, Helen, Baillet, Mark, Gilbert, Anthony, Jacobs, Michael, Charman, Christine, Mande, Priya, Nguyen-Van-Tam, Jonathan S, Semple, Malcolm G, Read, Robert C, Ferguson, Neil M, Openshaw, Peter J, Rapeport, Garth, Barclay, Wendy S, Catchpole, Andrew P, Chiu, Christopher
Published in Nature Medicine (01.02.2022)
Published in Nature Medicine (01.02.2022)
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SARS-CoV-2 lateral flow assays for possible use in national covid-19 seroprevalence surveys (React 2): diagnostic accuracy study
Moshe, Maya, Daunt, Anna, Flower, Barnaby, Simmons, Bryony, Brown, Jonathan C, Frise, Rebecca, Penn, Rebecca, Kugathasan, Ruthiran, Petersen, Claire, Stockmann, Helen, Ashby, Deborah, Riley, Steven, Atchison, Christina, Taylor, Graham P, Satkunarajah, Sutha, Naar, Lenny, Klaber, Robert, Badhan, Anjna, Rosadas, Carolina, Marchesin, Federica, Fernandez, Natalia, Sureda-Vives, Macià, Cheeseman, Hannah, O’Hara, Jessica, Shattock, Robin, Fontana, Gianluca, Pallett, Scott J C, Rayment, Michael, Jones, Rachael, Moore, Luke S P, Ashrafian, Hutan, Cherapanov, Peter, Tedder, Richard, McClure, Myra, Ward, Helen, Darzi, Ara, Elliott, Paul, Cooke, Graham S, Barclay, Wendy S
Published in BMJ (Online) (02.03.2021)
Published in BMJ (Online) (02.03.2021)
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Mammalian ANP32A and ANP32B Proteins Drive Differential Polymerase Adaptations in Avian Influenza Virus
Peacock, Thomas P, Sheppard, Carol M, Lister, Margaret G, Staller, Ecco, Frise, Rebecca, Swann, Olivia C, Goldhill, Daniel H, Long, Jason S, Barclay, Wendy S
Published in Journal of virology (31.05.2023)
Published in Journal of virology (31.05.2023)
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A self-amplifying RNA vaccine protects against SARS-CoV-2 (D614G) and Alpha variant of concern (B.1.1.7) in a transmission-challenge hamster model
Frise, Rebecca, Baillon, Laury, Zhou, Jie, Kugathasan, Ruthiran, Peacock, Thomas P., Brown, Jonathan C., Samnuan, Karnyart, McKay, Paul F., Shattock, Robin J., Barclay, Wendy S.
Published in Vaccine (03.05.2022)
Published in Vaccine (03.05.2022)
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Rapid, Portable, and Electricity-free Sample Extraction Method for Enhanced Molecular Diagnostics in Resource-Limited Settings
Pennisi, Ivana, Cavuto, Matthew L., Miglietta, Luca, Malpartida-Cardenas, Kenny, Stringer, Oliver W., Mantikas, Katerina-Theresa, Reid, Ruth, Frise, Rebecca, Moser, Nicolas, Randell, Paul, Davies, Frances, Bolt, Frances, Barclay, Wendy, Holmes, Alison, Georgiou, Pantelis, Rodriguez-Manzano, Jesus
Published in Analytical chemistry (Washington) (16.07.2024)
Published in Analytical chemistry (Washington) (16.07.2024)
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