Oral recombinant methioninase (o-rMETase) is superior to injectable rMETase and overcomes acquired gemcitabine resistance in pancreatic cancer
Kawaguchi, Kei, Miyake, Kentaro, Han, Qinghong, Li, Shukuan, Tan, Yuying, Igarashi, Kentaro, Kiyuna, Tasuku, Miyake, Masuyo, Higuchi, Takashi, Oshiro, Hiromichi, Zhang, Zhiying, Razmjooei, Sahar, Wangsiricharoen, Sintawat, Bouvet, Michael, Singh, Shree Ram, Unno, Michiaki, Hoffman, Robert M.
Published in Cancer letters (28.09.2018)
Published in Cancer letters (28.09.2018)
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Journal Article
Combination therapy of tumor-targeting Salmonella typhimurium A1-R and oral recombinant methioninase regresses a BRAF-V600E-negative melanoma
Kawaguchi, Kei, Higuchi, Takashi, Li, Shukuan, Han, Qinghong, Tan, Yuying, Igarashi, Kentaro, Zhao, Ming, Miyake, Kentaro, Kiyuna, Tasuku, Miyake, Masuyo, Ohshiro, Hiromichi, Sugisawa, Norihiko, Zhang, Zhiying, Razmjooei, Sahar, Wangsiricharoen, Sintawat, Chmielowski, Bartosz, Nelson, Scott D., Russell, Tara A., Dry, Sarah M., Li, Yunfeng, Eckardt, Mark A., Singh, Arun S., Singh, Shree Ram, Eilber, Fritz C., Unno, Michiaki, Hoffman, Robert M.
Published in Biochemical and biophysical research communications (18.09.2018)
Published in Biochemical and biophysical research communications (18.09.2018)
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A combination of irinotecan/cisplatinum and irinotecan/temozolomide or tumor-targeting Salmonella typhimurium A1-R arrest doxorubicin- and temozolomide-resistant myxofibrosarcoma in a PDOX mouse model
Kiyuna, Tasuku, Tome, Yasunori, Murakami, Takashi, Miyake, Kentaro, Igarashi, Kentaro, Kawaguchi, Kei, Oshiro, Hiromichi, Higuchi, Takashi, Miyake, Masuyo, Sugisawa, Norihiko, Zhang, Zhiying, Razmjooei, Sahar, Wangsiricharoen, Sintawat, Chmielowski, Bartosz, Nelson, Scott D., Russell, Tara A., Dry, Sarah M., Li, Yunfeng, Eckardt, Mark A., Singh, Arun S., Chawla, Sant, Kanaya, Fuminori, Eilber, Fritz C., Singh, Shree Ram, Zhao, Ming, Hoffman, Robert M.
Published in Biochemical and biophysical research communications (02.11.2018)
Published in Biochemical and biophysical research communications (02.11.2018)
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Journal Article
The combination of gemcitabine and docetaxel arrests a doxorubicin-resistant dedifferentiated liposarcoma in a patient-derived orthotopic xenograft model
Miyake, Kentaro, Higuchi, Takashi, Oshiro, Hiromichi, Zhang, Zhiying, Sugisawa, Norihiko, Park, Jun Ho, Razmjooei, Sahar, Katsuya, Yuki, Barangi, Maryam, Li, Yunfeng, Nelson, Scott D., Murakami, Takashi, Homma, Yuki, Hiroshima, Yukihiko, Matsuyama, Ryusei, Bouvet, Michael, Chawla, Sant P., Singh, Shree Ram, Endo, Itaru, Hoffman, Robert M.
Published in Biomedicine & pharmacotherapy (01.09.2019)
Published in Biomedicine & pharmacotherapy (01.09.2019)
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Journal Article
The combination of gemcitabine and nab-paclitaxel as a novel effective treatment strategy for undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model
Higuchi, Takashi, Kawaguchi, Kei, Miyake, Kentaro, Oshiro, Hiromichi, Zhang, Zhiying, Razmjooei, Sahar, Wangsiricharoen, Sintawat, Igarashi, Kentaro, Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Miwa, Shinji, Nelson, Scott D., Dry, Sarah M., Li, Yunfeng, Chawla, Sant P., Eilber, Frederick C., Singh, Shree Ram, Tsuchiya, Hiroyuki, Hoffman, Robert M.
Published in Biomedicine & pharmacotherapy (01.03.2019)
Published in Biomedicine & pharmacotherapy (01.03.2019)
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Journal Article
Regorafenib regressed a doxorubicin-resistant Ewing’s sarcoma in a patient-derived orthotopic xenograft (PDOX) nude mouse model
Miyake, Kentaro, Kiyuna, Tasuku, Kawaguchi, Kei, Higuchi, Takashi, Oshiro, Hiromichi, Zhang, Zhiying, Wangsiricharoen, Sintawat, Razmjooei, Sahar, Li, Yunfeng, Nelson, Scott D., Murakami, Takashi, Hiroshima, Yukihiko, Matsuyama, Ryusei, Bouvet, Michael, Chawla, Sant P., Singh, Shree Ram, Endo, Itaru, Hoffman, Robert M.
Published in Cancer chemotherapy and pharmacology (01.05.2019)
Published in Cancer chemotherapy and pharmacology (01.05.2019)
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Journal Article
Synergy of oral recombinant methioninase (rMETase) and 5-fluorouracil on poorly differentiated gastric cancer
Miyake, Masuyo, Miyake, Kentaro, Han, Qinghong, Igarashi, Kentaro, Kawaguchi, Kei, Barangi, Maryam, Kiyuna, Tasuku, Sugisawa, Norihiko, Higuchi, Takashi, Oshiro, Hiromichi, Zhang, Zhiying, Razmjooei, Sahar, Bouvet, Michael, Endo, Itaru, Hoffman, Robert M.
Published in Biochemical and biophysical research communications (05.02.2023)
Published in Biochemical and biophysical research communications (05.02.2023)
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Journal Article
Oral Recombinant Methioninase Combined with Caffeine and Doxorubicin Induced Regression of a Doxorubicin-resistant Synovial Sarcoma in a PDOX Mouse Model
Higuchi, Takashi, Kawaguchi, Kei, Miyake, Kentaro, Han, Qinghong, Tan, Yuying, Oshiro, Hiromichi, Sugisawa, Norihiko, Zhang, Zhiying, Razmjooei, Sahar, Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Miwa, Shinji, Igarashi, Kentaro, Chawla, Sant P, Singh, Arun S, Eilber, Frederick C, Singh, Shree Ram, Tsuchiya, Hiroyuki, Hoffman, Robert M
Published in Anticancer research (01.10.2018)
Published in Anticancer research (01.10.2018)
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Journal Article
Oral Recombinant Methioninase Overcomes Colorectal-cancer Liver Metastasis Resistance to the Combination of 5-Fluorouracil and Oxaliplatinum in a Patient-derived Orthotopic Xenograft Mouse Model
Oshiro, Hiromichi, Tome, Yasunori, Kiyuna, Tasuku, Yoon, Sang Nam, Lwin, Thinzar M, Han, Qinghong, Tan, Yuying, Miyake, Kentaro, Higuchi, Takashi, Sugisawa, Norihiko, Katsuya, Yuki, Park, Jun Ho, Zang, Zhiying, Razmjooei, Sahar, Bouvet, Michael, Clary, Bryan, Singh, Shree Ram, Kanaya, Fuminori, Nishida, Kotaro, Hoffman, Robert M
Published in Anticancer research (01.09.2019)
Published in Anticancer research (01.09.2019)
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Journal Article
Oral Recombinant Methioninase, Combined With Oral Caffeine and Injected Cisplatinum, Overcome Cisplatinum-Resistance and Regresses Patient-derived Orthotopic Xenograft Model of Osteosarcoma
Higuchi, Takashi, Oshiro, Hiromichi, Miyake, Kentaro, Sugisawa, Norihiko, Han, Qinghong, Tan, Yuying, Park, Junho, Zhang, Zhiying, Razmjooei, Sahar, Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Miwa, Shinji, Igarashi, Kentaro, Bouvet, Michael, Chawla, Sant P, Singh, Shree Ram, Tsuchiya, Hiroyuki, Hoffman, Robert M
Published in Anticancer research (01.09.2019)
Published in Anticancer research (01.09.2019)
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Journal Article
A novel patient-derived orthotopic xenograft (PDOX) mouse model of highly-aggressive liver metastasis for identification of candidate effective drug-combinations
Zhang, Zhiying, Hu, Kaiwen, Miyake, Kentaro, Kiyuna, Tasuku, Oshiro, Hiromichi, Wangsiricharoen, Sintawat, Kawaguchi, Kei, Higuchi, Takashi, Razmjooei, Sahar, Miyake, Masuyo, Chawla, Sant P, Singh, Shree Ram, Hoffman, Robert M
Published in Scientific reports (18.11.2020)
Published in Scientific reports (18.11.2020)
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Journal Article
A Novel Orthotopic Mouse Model of Lung Metastasis Using Fluorescent Patient-derived Osteosarcoma Cells
Oshiro, Hiromichi, Tome, Yasunori, Miyake, Kentaro, Higuchi, Takashi, Sugisawa, Norihiko, Park, Jun Ho, Zhang, Zhiying, Razmjooei, Sahar, Kanaya, Fuminori, Nishida, Kotaro, Hoffman, Robert M
Published in Anticancer research (01.02.2021)
Published in Anticancer research (01.02.2021)
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Journal Article
Olaratumab combined with doxorubicin and ifosfamide overcomes individual doxorubicin and olaratumab resistance of an undifferentiated soft-tissue sarcoma in a PDOX mouse model
Higuchi, Takashi, Miyake, Kentaro, Sugisawa, Norihiko, Oshiro, Hiromichi, Zhang, Zhiying, Razmjooei, Sahar, Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Miwa, Shinji, Igarashi, Kentaro, Bouvet, Michael, Singh, Shree Ram, Tsuchiya, Hiroyuki, Hoffman, Robert M.
Published in Cancer letters (01.06.2019)
Published in Cancer letters (01.06.2019)
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Journal Article
Peritoneal Metastases in a Patient-derived Orthotopic Xenograft (PDOX) Model of Colon Cancer Imaged Non-invasively via Red Fluorescent Protein Labeled Stromal Cells
Park, Jun Ho, Zhao, Ming, Oshiro, Hiromichi, Miyake, Kentaro, Higuchi, Takashi, Reynoso, Jose, Razmjooei, Sahar, Bouvet, Michael, Clary, Bryan, Zhang, Zhiying, Sugisawa, Norihiko, Yamamoto, Jun, Singh, Shree Ram, Hoffman, Robert M
Published in Anticancer research (01.07.2019)
Published in Anticancer research (01.07.2019)
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Journal Article
Gemcitabine combined with docetaxel precisely regressed a recurrent leiomyosarcoma peritoneal metastasis in a patient-derived orthotopic xenograft (PDOX) model
Miyake, Kentaro, Kiyuna, Tasuku, Miyake, Masuyo, Kawaguchi, Kei, Zhang, Zhiying, Wangsiricharoen, Sintawat, Razmjooei, Sahar, Oshiro, Hiromichi, Higuchi, Takashi, Li, Yunfeng, Nelson, Scott D., Murakami, Takashi, Hiroshima, Yukihiko, Kumamoto, Takafumi, Matsuyama, Ryusei, Bouvet, Michael, Singh, Shree Ram, Chawla, Sant P., Endo, Itaru, Hoffman, Robert M.
Published in Biochemical and biophysical research communications (19.02.2019)
Published in Biochemical and biophysical research communications (19.02.2019)
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Journal Article
Detection of Metastasis in a Patient-derived Orthotopic Xenograft (PDOX) Model of Undifferentiated Pleomorphic Sarcoma with Red Fluorescent Protein
Oshiro, Hiromichi, Kiyuna, Tasuku, Tome, Yasunori, Miyake, Kentaro, Kawaguchi, Kei, Higuchi, Takashi, Miyake, Masuyo, Zhang, Zhiying, Razmjooei, Sahar, Barangi, Maryam, Wangsiricharoen, Sintawat, Nelson, Scott D, Li, Yunfeng, Bouvet, Michael, Singh, Shree Ram, Kanaya, Fuminori, Hoffman, Robert M
Published in Anticancer research (01.01.2019)
Published in Anticancer research (01.01.2019)
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Journal Article
Regorafenib regressed a doxorubicin-resistant Ewing’s sarcoma in a patient-derived orthotopic xenograft (PDOX) nude mouse model
Miyake, Kentaro, Kiyuna, Tasuku, Kawaguchi, Kei, Higuchi, Takashi, Oshiro, Hiromichi, Zhang, Zhiying, Wangsiricharoen, Sintawat, Razmjooei, Sahar, Li, Yunfeng, Nelson, Scott D., Murakami, Takashi, Hiroshima, Yukihiko, Matsuyama, Ryusei, Bouvet, Michael, Chawla, Sant P., Singh, Shree Ram, Endo, Itaru, Hoffman, Robert M.
Published in Cancer chemotherapy and pharmacology (01.05.2019)
Published in Cancer chemotherapy and pharmacology (01.05.2019)
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Journal Article
The combination of olaratumab with gemcitabine and docetaxel arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft mouse model
Higuchi, Takashi, Miyake, Kentaro, Sugisawa, Norihiko, Oshiro, Hiromichi, Zhang, Zhiying, Razmjooei, Sahar, Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Miwa, Shinji, Igarashi, Kentaro, Bouvet, Michael, Singh, Shree Ram, Tsuchiya, Hiroyuki, Hoffman, Robert M.
Published in Cancer chemotherapy and pharmacology (01.06.2019)
Published in Cancer chemotherapy and pharmacology (01.06.2019)
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Journal Article
Combining Tumor-Selective Bacterial Therapy with Salmonella typhimurium A1-R and Cancer Metabolism Targeting with Oral Recombinant Methioninase Regressed an Ewing's Sarcoma in a Patient-Derived Orthotopic Xenograft Model
Miyake, Kentaro, Kiyuna, Tasuku, Li, Shukuan, Han, Qinghong, Tan, Yuying, Zhao, Ming, Oshiro, Hiromichi, Kawaguchi, Kei, Higuchi, Takashi, Zhang, Zhiying, Razmjooei, Sahar, Barangi, Maryam, Wangsiricharoen, Sintawat, Murakami, Takashi, Singh, Arun S, Li, Yunfeng, Nelson, Scott D, Eilber, Fritz C, Bouvet, Michael, Hiroshima, Yukihiko, Chishima, Takashi, Matsuyama, Ryusei, Singh, Shree Ram, Endo, Itaru, Hoffman, Robert M
Published in Chemotherapy (Basel) (01.01.2018)
Published in Chemotherapy (Basel) (01.01.2018)
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Journal Article
Temozolomide targets and arrests a doxorubicin-resistant follicular dendritic-cell sarcoma patient-derived orthotopic xenograft mouse model
Oshiro, Hiromichi, Tome, Yasunori, Kiyuna, Tasuku, Miyake, Kentaro, Kawaguchi, Kei, Higuchi, Takashi, Miyake, Masuyo, Zang, Zhiying, Razmjooei, Sahar, Barangi, Maryam, Wangsiricharoen, Sintawat, Nelson, Scott D., Li, Yunfeng, Bouvet, Michael, Singh, Shree Ram, Kanaya, Fuminori, Hoffman, Robert M.
Published in Tissue & cell (01.06.2019)
Published in Tissue & cell (01.06.2019)
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