Evolution of the Petasis−Ferrier Union/Rearrangement Tactic: Construction of Architecturally Complex Natural Products Possessing the Ubiquitous cis-2,6-Substituted Tetrahydropyran Structural Element
Smith, Amos B, Fox, Richard J, Razler, Thomas M
Published in Accounts of chemical research (01.05.2008)
Published in Accounts of chemical research (01.05.2008)
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A Preparatively Convenient Ligand-Free Catalytic PEG 2000 Suzuki−Miyaura Coupling
Razler, Thomas M, Hsiao, Yi, Qian, Feng, Fu, Ruiling, Khan, Rana Kashif, Doubleday, Wendel
Published in Journal of organic chemistry (06.02.2009)
Published in Journal of organic chemistry (06.02.2009)
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Development of a Practical Synthesis of Functionalized Azaxanthene-Derived Nonsteroidal Glucocorticoid Receptor Modulators
Conlon, David A, Natalie, Kenneth J, Cuniere, Nicolas, Razler, Thomas M, Zhu, Jason, de Mas, Nuria, Tymonko, Steven, Fraunhoffer, Kenneth J, Sortore, Eric, Rosso, Victor W, Xu, Zhongmin, Adams, Monica L, Patel, Anisha, Huang, Jun, Gong, Hua, Weinstein, David S, Quiroz, Fernando, Chen, Doris C
Published in Organic process research & development (20.05.2016)
Published in Organic process research & development (20.05.2016)
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Adventures in Atropisomerism: Total Synthesis of a Complex Active Pharmaceutical Ingredient with Two Chirality Axes
Beutner, Gregory, Carrasquillo, Ronald, Geng, Peng, Hsiao, Yi, Huang, Eric C, Janey, Jacob, Katipally, Kishta, Kolotuchin, Sergei, La Porte, Thomas, Lee, Andrew, Lobben, Paul, Lora-Gonzalez, Federico, Mack, Brendan, Mudryk, Boguslaw, Qiu, Yuping, Qian, Xinhua, Ramirez, Antonio, Razler, Thomas M, Rosner, Thorsten, Shi, Zhongping, Simmons, Eric, Stevens, Jason, Wang, Jianji, Wei, Carolyn, Wisniewski, Steven R, Zhu, Ye
Published in Organic letters (06.07.2018)
Published in Organic letters (06.07.2018)
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Systematic Optimization of a Robust Telescoped Process for a BTK Inhibitor with Atropisomer Control by High-Throughput Experimentation, Design of Experiments, and Linear Regression
Gonzalez, Federico Lora, Wisniewski, Steven R, Katipally, Kishta, Stevens, Jason M, Rosso, Victor, Mack, Brendan, Razler, Thomas M
Published in Organic process research & development (21.06.2019)
Published in Organic process research & development (21.06.2019)
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Development of a Kilogram-Scale Process for the Enantioselective Synthesis of 3‑Isopropenyl-cyclohexan-1-one via Rh/DTBM-SEGPHOS-Catalyzed Asymmetric Hayashi Addition Enabled by 1,3-Diol Additives
Simmons, Eric M, Mudryk, Boguslaw, Lee, Andrew G, Qiu, Yuping, Razler, Thomas M, Hsiao, Yi
Published in Organic process research & development (20.10.2017)
Published in Organic process research & development (20.10.2017)
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Adventures in Atropisomerism: Development of a Robust, Diastereoselective, Lithium-Catalyzed Atropisomer-Forming Active Pharmaceutical Ingredient Step
Wisniewski, Steven R, Carrasquillo-Flores, Ronald, Lora Gonzalez, Federico, Ramirez, Antonio, Casey, Matthew, Soumeillant, Maxime, Razler, Thomas M, Mack, Brendan
Published in Organic process research & development (19.10.2018)
Published in Organic process research & development (19.10.2018)
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Scalability and Predictability of Polymorph Transformations Under High Shear
Carrasquillo-Flores, Ronald, Wisniewski, Steven R, Daftary, Vivek, Lora-Gonzalez, Federico, Rosenbaum, Tamar, Wethman, Robert, Huang, Ming-Hsing, Wasylyk, John M, Selekman, Joshua, Choi, Candi, Mack, Brendan, Razler, Thomas M, Engstrom, Joshua
Published in Organic process research & development (16.04.2021)
Published in Organic process research & development (16.04.2021)
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A Second-Generation Total Synthesis of (+)-Phorboxazole A
Smith, Amos B, Razler, Thomas M, Ciavarri, Jeffrey P, Hirose, Tomoyasu, Ishikawa, Tomoyasu, Meis, Regina M
Published in Journal of organic chemistry (15.02.2008)
Published in Journal of organic chemistry (15.02.2008)
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Degradation Kinetics and Mechanism of an Oxadiazole Derivative, Design of a Stable Drug Product for BMS-708163, a γ-Secretase Inhibitor Drug Candidate
Hartley, Ruiling F., Huang, Yande, Cassidy, Michael, Razler, Thomas M., Qian, Feng, Hussain, Munir A.
Published in Journal of pharmaceutical sciences (01.09.2012)
Published in Journal of pharmaceutical sciences (01.09.2012)
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Synthesis and Biological Evaluation of Phorboxazole Congeners Leading to the Discovery and Preparative-Scale Synthesis of (+)-Chlorophorboxazole A Possessing Picomolar Human Solid Tumor Cell Growth Inhibitory Activity
Smith, Amos B, Razler, Thomas M, Meis, Regina M, Pettit, George R
Published in Journal of organic chemistry (15.02.2008)
Published in Journal of organic chemistry (15.02.2008)
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Phorboxazole synthetic studies: design, synthesis and biological evaluation of phorboxazole A and hemi-phorboxazole A related analogues
Smith, Amos B., Hogan, Anne-Marie L., Liu, Zhuqing, Razler, Thomas M., Meis, Regina M., Morinaka, Brandon I., Molinski, Tadeusz F.
Published in Tetrahedron (08.07.2011)
Published in Tetrahedron (08.07.2011)
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A Robust Three-Step Telescoped Synthesis of Electron- Deficient Amide Substituted Arylboronic Acids
Zhu, Jason, Razler, Thomas M, Xu, Zhongmin, Conlon, David A, Sortore, Eric W, Fritz, Alan W, Demerzhan, Roman, Sweeney, Jason T
Published in Organic process research & development (18.03.2011)
Published in Organic process research & development (18.03.2011)
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(+)-Phorboxazole A Synthetic Studies. Identification of a Series of Highly Cytotoxic C(45−46) Analogues
Smith, Amos B, Razler, Thomas M, Pettit, George R, Chapuis, Jean-Charles
Published in Organic letters (29.09.2005)
Published in Organic letters (29.09.2005)
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Design and Synthesis of a Potent Phorboxazole C(11−15) Acetal Analogue
Smith, Amos B, Razler, Thomas M, Meis, Regina M, Pettit, George R
Published in Organic letters (16.02.2006)
Published in Organic letters (16.02.2006)
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테트라히드로카르바졸 카르복스아미드 화합물의 제조 방법
GENG PENG, HUANG ERIC C, KATIPALLY KISHTA, WANG JIANJI, LEE ANDREW, RAZLER THOMAS M, WISNIEWSKI STEVEN R, MUDRYK BOGUSLAW, QIAN XINHUA, ZHU YE, WEI CAROLYN S, CARRASQUILLO RONALD
Year of Publication 09.08.2019
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Year of Publication 09.08.2019
Patent
N-((1R,2S,5R)-5-(tert-부틸아미노)-2-((S)-3-(7-tert-부틸피라졸로[1,5-a][1,3,5]트리아진-4-일아미노)-2-옥소피롤리딘-1-일)시클로헥실)아세트아미드의 제조 방법
HICKEY MATTHEW R, RAZLER THOMAS M, LUO HELEN Y, LAUSER KATHLEEN, EASTGATE MARTIN D, AYTAR BURCU SELIN, GONZALEZ BOBES FRANCISCO, BOROVIKA ALINA, LEE HONG GEUN, DEERBERG JOERG, SFOUGGATAKIS CHRIS, LEAHY DAVID K, SOUMEILLANT MAXIME C.D, FAN YU, ZHU YE, KOPP NATHANIEL DAVID, CHAN COLLIN, SAVAGE SCOTT A, DOMAGALSKI NATHAN R, FENSTER MICHAEL DAVID BENGT, GREEN REBECCA A, FOREST ROBERT V, ZHENG BIN, ZARETSKY SERGE, LA CRUZ THOMAS E
Year of Publication 24.03.2020
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Year of Publication 24.03.2020
Patent
Development of a Kilogram-Scale Process for the Enantioselective Synthesis of 3-lsopropenyl-cyclohexan-1-one via Rh/DTBM-SEGPHOS-Catalyzed Asymmetric Hayashi Addition Enabled by 1,3-Diol Additives
Simmons, Eric M., Mudryk, Boguslaw, Lee, Andrew G., Qiu, Yuping, Razler, Thomas M., Hsiao, Yi
Published in Organic process research & development (01.10.2017)
Published in Organic process research & development (01.10.2017)
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Journal Article
Degradation kinetics and mechanism of an oxadiazole derivative, design of a stable drug product for BMS-708163, a [gamma]-secretase inhibitor drug candidate
Hartley, Ruiling F, Huang, Yande, Cassidy, Michael, Razler, Thomas M, Qian, Feng, Hussain, Munir A
Published in Journal of pharmaceutical sciences (01.09.2012)
Published in Journal of pharmaceutical sciences (01.09.2012)
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