T-Cell-Inflamed Gene-Expression Profile, Programmed Death Ligand 1 Expression, and Tumor Mutational Burden Predict Efficacy in Patients Treated With Pembrolizumab Across 20 Cancers: KEYNOTE-028
Ott, Patrick A, Bang, Yung-Jue, Piha-Paul, Sarina A, Razak, Albiruni R Abdul, Bennouna, Jaafar, Soria, Jean-Charles, Rugo, Hope S, Cohen, Roger B, O'Neil, Bert H, Mehnert, Janice M, Lopez, Juanita, Doi, Toshihiko, van Brummelen, Emilie M J, Cristescu, Razvan, Yang, Ping, Emancipator, Kenneth, Stein, Karen, Ayers, Mark, Joe, Andrew K, Lunceford, Jared K
Published in Journal of clinical oncology (01.02.2019)
Published in Journal of clinical oncology (01.02.2019)
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Journal Article
Safety and antitumor activity of the anti-PD-1 antibody pembrolizumab in patients with advanced colorectal carcinoma
O'Neil, Bert H, Wallmark, John M, Lorente, David, Elez, Elena, Raimbourg, Judith, Gomez-Roca, Carlos, Ejadi, Samuel, Piha-Paul, Sarina A, Stein, Mark N, Abdul Razak, Albiruni R, Dotti, Katia, Santoro, Armando, Cohen, Roger B, Gould, Marlena, Saraf, Sanatan, Stein, Karen, Han, Sae-Won
Published in PloS one (28.12.2017)
Published in PloS one (28.12.2017)
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Journal Article
Effect of Doxorubicin Plus Olaratumab vs Doxorubicin Plus Placebo on Survival in Patients With Advanced Soft Tissue Sarcomas: The ANNOUNCE Randomized Clinical Trial
Tap, William D, Wagner, Andrew J, Schöffski, Patrick, Martin-Broto, Javier, Krarup-Hansen, Anders, Ganjoo, Kristen N, Yen, Chueh-Chuan, Abdul Razak, Albiruni R, Spira, Alexander, Kawai, Akira, Le Cesne, Axel, Van Tine, Brian A, Naito, Yoichi, Park, Se Hoon, Fedenko, Alexander, Pápai, Zsuzsanna, Soldatenkova, Victoria, Shahir, Ashwin, Mo, Gary, Wright, Jennifer, Jones, Robin L
Published in JAMA : the journal of the American Medical Association (07.04.2020)
Published in JAMA : the journal of the American Medical Association (07.04.2020)
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Journal Article
Safety and Efficacy of Nivolumab in Combination With Ipilimumab in Metastatic Renal Cell Carcinoma: The CheckMate 016 Study
Hammers, Hans J, Plimack, Elizabeth R, Infante, Jeffrey R, Rini, Brian I, McDermott, David F, Lewis, Lionel D, Voss, Martin H, Sharma, Padmanee, Pal, Sumanta K, Razak, Albiruni R Abdul, Kollmannsberger, Christian, Heng, Daniel Y C, Spratlin, Jennifer, McHenry, M Brent, Amin, Asim
Published in Journal of clinical oncology (01.12.2017)
Published in Journal of clinical oncology (01.12.2017)
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Journal Article
Pharmacokinetics of Selinexor: The First-in-Class Selective Inhibitor of Nuclear Export
Bader, Justin C., Abdul Razak, Albiruni R., Shacham, Sharon, Xu, Hongmei
Published in Clinical pharmacokinetics (01.08.2021)
Published in Clinical pharmacokinetics (01.08.2021)
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Journal Article
First-in-Class, First-in-Human Phase I Study of Selinexor, a Selective Inhibitor of Nuclear Export, in Patients With Advanced Solid Tumors
Abdul Razak, Albiruni R, Mau-Soerensen, Morten, Gabrail, Nashat Y, Gerecitano, John F, Shields, Anthony F, Unger, Thaddeus J, Saint-Martin, Jean R, Carlson, Robert, Landesman, Yosef, McCauley, Dilara, Rashal, Tami, Lassen, Ulrik, Kim, Richard, Stayner, Lee-Anne, Mirza, Mansoor R, Kauffman, Michael, Shacham, Sharon, Mahipal, Amit
Published in Journal of clinical oncology (01.12.2016)
Published in Journal of clinical oncology (01.12.2016)
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Journal Article
Co-Targeting of MDM2 and CDK4/6 with Siremadlin and Ribociclib for the Treatment of Patients with Well-Differentiated or Dedifferentiated Liposarcoma: Results from a Proof-of-Concept, Phase Ib Study
Abdul Razak, Albiruni R, Bauer, Sebastian, Suarez, Cristina, Lin, Chia-Chi, Quek, Richard, Hütter-Krönke, Marie Luise, Cubedo, Ricardo, Ferretti, Stephane, Guerreiro, Nelson, Jullion, Astrid, Orlando, Elena J, Clementi, Giorgia, Sand Dejmek, Janna, Halilovic, Ensar, Fabre, Claire, Blay, Jean-Yves, Italiano, Antoine
Published in Clinical cancer research (15.03.2022)
Published in Clinical cancer research (15.03.2022)
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Journal Article
Evolution of Clinical Trial Design in Early Drug Development: Systematic Review of Expansion Cohort Use in Single-Agent Phase I Cancer Trials
MANJI, Arif, BRANA, Irene, AMIR, Eitan, TOMLINSON, George, TANNOCK, Ian F, BEDARD, Philippe L, OZA, Amit, SIU, Lillian L, ABDUL RAZAK, Albiruni R
Published in Journal of clinical oncology (20.11.2013)
Published in Journal of clinical oncology (20.11.2013)
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Journal Article
Underreporting of Symptomatic Adverse Events in Phase I Clinical Trials
Veitch, Zachary W, Shepshelovich, Daniel, Gallagher, Christina, Wang, Lisa, Abdul Razak, Albiruni R, Spreafico, Anna, Bedard, Philippe L, Siu, Lillian L, Minasian, Lori, Hansen, Aaron R
Published in JNCI : Journal of the National Cancer Institute (02.08.2021)
Published in JNCI : Journal of the National Cancer Institute (02.08.2021)
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Journal Article
The Future of Clinical Trial Design in Oncology
Spreafico, Anna, Hansen, Aaron R, Abdul Razak, Albiruni R, Bedard, Philippe L, Siu, Lillian L
Published in Cancer discovery (01.04.2021)
Published in Cancer discovery (01.04.2021)
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Journal Article
Phase 1 study of GSK3368715, a type I PRMT inhibitor, in patients with advanced solid tumors
El-Khoueiry, Anthony B, Clarke, James, Neff, Tobias, Crossman, Tim, Ratia, Nirav, Rathi, Chetan, Noto, Paul, Tarkar, Aarti, Garrido-Laguna, Ignacio, Calvo, Emiliano, Rodón, Jordi, Tran, Ben, O'Dwyer, Peter J, Cuker, Adam, Abdul Razak, Albiruni R
Published in British journal of cancer (10.08.2023)
Published in British journal of cancer (10.08.2023)
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Journal Article
Nasopharyngeal carcinoma: The next challenges
Razak, Albiruni R.A, Siu, Lillian L, Liu, Fei-Fei, Ito, Emma, O’Sullivan, Brian, Chan, Kelvin
Published in European journal of cancer (1990) (01.07.2010)
Published in European journal of cancer (1990) (01.07.2010)
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Journal Article
Early phase clinical trials to identify optimal dosing and safety
Cook, Natalie, Hansen, Aaron R., Siu, Lillian L., Abdul Razak, Albiruni R.
Published in Molecular oncology (01.05.2015)
Published in Molecular oncology (01.05.2015)
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Journal Article
Real-word experience of pazopanib and sorafenib in patients with desmoid tumors: A CanSaRCC multi-center study
Noujaim, Jonathan, Gupta, Abha A., Holloway, Caroline L., Saleh, Ramy, Srikanthan, Amirrtha, Lemieux, Christopher, Soroka, Hagit Peretz, Tibout, Pauline, Turcotte, Robert, Feng, Xiaolan, Abdul Razak, Albiruni R., Costa, Philippos
Published in European journal of cancer (1990) (01.07.2024)
Published in European journal of cancer (1990) (01.07.2024)
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Journal Article
A phase I study of VS-6063, a second-generation focal adhesion kinase inhibitor, in patients with advanced solid tumors
Jones, Suzanne F., Siu, Lillian L., Bendell, Johanna C., Cleary, James M., Razak, Albiruni R. A., Infante, Jeffrey R., Pandya, Shuchi S., Bedard, Philippe L., Pierce, Kristen J., Houk, Brett, Roberts, W. Gregory, Shreeve, S. Martin, Shapiro, Geoffrey I.
Published in Investigational new drugs (01.10.2015)
Published in Investigational new drugs (01.10.2015)
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Journal Article
Tumor reactive γδ T cells contribute to a complete response to PD-1 blockade in a Merkel cell carcinoma patient
Lien, Scott C, Ly, Dalam, Yang, S Y Cindy, Wang, Ben X, Clouthier, Derek L, St Paul, Michael, Gadalla, Ramy, Noamani, Babak, Garcia-Batres, Carlos R, Boross-Harmer, Sarah, Bedard, Philippe L, Pugh, Trevor J, Spreafico, Anna, Hirano, Naoto, Razak, Albiruni R A, Ohashi, Pamela S
Published in Nature communications (06.02.2024)
Published in Nature communications (06.02.2024)
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Journal Article
Systemic and local immunity following adoptive transfer of NY-ESO-1 SPEAR T cells in synovial sarcoma
Ramachandran, Indu, Lowther, Daniel E., Dryer-Minnerly, Rebecca, Wang, Ruoxi, Fayngerts, Svetlana, Nunez, Daniel, Betts, Gareth, Bath, Natalie, Tipping, Alex J., Melchiori, Luca, Navenot, Jean-Marc, Glod, John, Mackall, Crystal L., D’Angelo, Sandra P., Araujo, Dejka M., Chow, Warren A., Demetri, George D., Druta, Mihaela, Van Tine, Brian A., Grupp, Stephan A., Abdul Razak, Albiruni R., Wilky, Breelyn, Iyengar, Malini, Trivedi, Trupti, Winkle, Erin Van, Chagin, Karen, Amado, Rafael, Binder, Gwendolyn K., Basu, Samik
Published in Journal for immunotherapy of cancer (24.10.2019)
Published in Journal for immunotherapy of cancer (24.10.2019)
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Journal Article
A Phase 1B open-label study of gedatolisib (PF-05212384) in combination with other anti-tumour agents for patients with advanced solid tumours and triple-negative breast cancer
Curigliano, Giuseppe, Shapiro, Geoffrey I, Kristeleit, Rebecca S, Abdul Razak, Albiruni R, Leong, Stephen, Alsina, Maria, Giordano, Antonio, Gelmon, Karen A, Stringer-Reasor, Erica, Vaishampayan, Ulka N, Middleton, Mark, Olszanski, Anthony J, Rugo, Hope S, Kern, Kenneth A, Pathan, Nuzhat, Perea, Rachelle, Pierce, Kristen J, Mutka, Sarah C, Wainberg, Zev A
Published in British journal of cancer (26.01.2023)
Published in British journal of cancer (26.01.2023)
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Journal Article
Evaluation of the patient experience of symptomatic adverse events on Phase I clinical trials using PRO-CTCAE
Watson, Geoffrey A, Veitch, Zachary W, Shepshelovich, Daniel, Liu, Zhihui Amy, Spreafico, Anna, Abdul Razak, Albiruni R, Bedard, Philippe L, Siu, Lillian L, Minasian, Lori, Hansen, Aaron R
Published in British journal of cancer (01.11.2022)
Published in British journal of cancer (01.11.2022)
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Journal Article